BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0006.p (898 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2125 [E] COG0308 Aminopeptidase N Rso Ralstonia solanacearum 1134 0.0 PA3083 [E] COG0308 Aminopeptidase N Pae Pseudomonas aeruginosa 909 0.0 YPO1414 [E] COG0308 Aminopeptidase N Ype Yersinia pestis 867 0.0 ECs1015 [E] COG0308 Aminopeptidase N Ecs Escherichia coli O157:H7 859 0.0 pepN [E] COG0308 Aminopeptidase N Eco Escherichia coli K12 857 0.0 >RSc2125 [E] COG0308 Aminopeptidase N Rso Ralstonia solanacearum Length = 905 Score = 1134 bits (2933), Expect = 0.0, Method: Compositional matrix adjust. Identities = 592/923 (64%), Positives = 688/923 (74%), Gaps = 45/923 (4%) Query: 1 MRTDTPQTIYRKDYAAPNYLADTVEMGFDLDPADTHVATRITLTRNPAAKGRDLILFGEE 60 +RTDT TIYR+DY AP + D V + DL P T + +R+ +TR A G L L GE Sbjct: 2 LRTDTAVTIYRQDYTAPAFRIDDVALEIDLVPERTRIVSRLRMTRLRA--GAPLTLVGEG 59 Query: 61 LELVALRLNGKTLSQAKGDFRIAGGVLTIPAAPAKV----TLEIETLVHPDRNTSLMGLY 116 LEL + L+G+ L + D G LTI AAPA+ TLE+ T +P N+SLMGLY Sbjct: 60 LELAGVTLDGQALPGIQPD----GDTLTIEAAPAQADTAFTLELTTFCNPAANSSLMGLY 115 Query: 117 VSNGNFFTQCEAEGFRKITYFPDRPDVMAKFTVMLRADKARYPVLLSNGNLIEEGELPDG 176 VSN NFFTQCEAEGFRKITYF DRPDVMA +TV LRA KA YPVLLSNGNL+ + +LPDG Sbjct: 116 VSNDNFFTQCEAEGFRKITYFLDRPDVMAVYTVTLRAAKADYPVLLSNGNLVSQRDLPDG 175 Query: 177 RHYAKWEDPFKKPSYLFALVAGQLVCQEETVRLHSGRDALLQVWVEEGNLDKTQHAMESL 236 RH A W DPFKKPSYLFALVAG L C E + SG++ LLQVWVE +L KT+HAM+SL Sbjct: 176 RHEAVWHDPFKKPSYLFALVAGTLECIEARILSASGKEKLLQVWVEPHDLGKTRHAMDSL 235 Query: 237 KNSITWDVERFGLDLDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPRIATDVDFAN 296 ++I WD +RFGL+LDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLAN ATDVDFAN Sbjct: 236 IHAIRWDEQRFGLELDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANAETATDVDFAN 295 Query: 297 IEAVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFS-----------ADMIGSDS 345 IE+VVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFS + + S Sbjct: 296 IESVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMAAQAAAQAGNAAAAAS 355 Query: 346 GRAVKRIDDVRVLRQAQFPEDAGPMAHPVRPDSFVEINNFYTVTVYEKGAEVVRMYQTLL 405 RAVKRI+DVR+LRQ QFPEDAGPMAHPVRPDS+ EINNFYTVTVYEKGAEVVRMYQTLL Sbjct: 356 ARAVKRIEDVRLLRQVQFPEDAGPMAHPVRPDSYEEINNFYTVTVYEKGAEVVRMYQTLL 415 Query: 406 GRDGFRKGMDLYFKRHDGQAVTCDDFRAAMADANGRDLSQFERWYSQAGTPLVQASADYD 465 GR+ FRKGMDLYF+RHDGQAVTCDDFRAAMADANGRDL++F RWYSQAGTP+V +D Sbjct: 416 GREAFRKGMDLYFQRHDGQAVTCDDFRAAMADANGRDLTRFGRWYSQAGTPVVAVEGRHD 475 Query: 466 AKRKTLTLTLEQSC-----PATPGQKKKQPFHIPVAVGLLDAQGRDLALTLQGEKKAGA- 519 A +T TLTL Q C G KQPFHIP A+GLLDAQGRDL L L+GE + Sbjct: 476 AATRTYTLTLRQRCEPVGIETADGSLHKQPFHIPFAIGLLDAQGRDLPLRLRGEPASAQP 535 Query: 520 -TTRVLELTKAKQSFTFINVDEKPVPSLLRGFSAPVVLQYDYSDAELAFLMAHDSDAFNR 578 TTRVL+ T+A+Q+F F +V E P+PSLLR FSAPVV++Y Y+ +L FL+AHD+D FNR Sbjct: 536 LTTRVLDFTEAEQTFVFEDVAEAPLPSLLRNFSAPVVVEYGYTTGQLTFLLAHDADPFNR 595 Query: 579 WEAGQRLATRRLLNLTVAVQAARQSGHVVAVDTVLNNIEHDGALADALRATLKDESLDPA 638 WEAGQRLAT LL + VQ R + D AL +ALRA L D SLDPA Sbjct: 596 WEAGQRLATDALLRMVADVQQGRTP-------------QVDPALVEALRAVLADASLDPA 642 Query: 639 FRELVLTLPSETMIAEQMEVIDPHAIHVARQFLRRSLARELRDDLLAVYHAHQTPGAYSP 698 FRE +L LP+ET +AE+M+V DP AIHVAR+ LRR+LA L + L YH T G Y+P Sbjct: 643 FREQMLILPAETYLAERMDVADPAAIHVARRALRRTLAEALGAEFLRAYHDSTTDGPYTP 702 Query: 699 DAASAGHRALKNVALSYLAELDDEEAMALAQQQDQDANNMTDRLAALSAVLNSAAPGKSE 758 DA SAG RAL+N+AL YLAE + EA+ALA+QQ A +MTDR+ AL+A++NS APG+ Sbjct: 703 DAVSAGKRALRNIALGYLAEAESAEALALAEQQYTSAASMTDRMGALAALVNSYAPGREA 762 Query: 759 ALQRFYAEFEQEALVIDKWFTLQA----TARNADVNTVRTLTEHPAFTLKNPNRARSLIF 814 AL FY F +ALVIDKWF LQA A + TVR L HPAFTL+NPNRAR+LIF Sbjct: 763 ALADFYTRFADDALVIDKWFALQAMQPGAAGKPTLATVRALMAHPAFTLRNPNRARALIF 822 Query: 815 SFCNGNPSAFHALDGNGYAFWAEQVIALNGSNPQVAARLARSLDRWRKYTPALQEKMRLA 874 SFC+GNP+ FHA DG+GYAFWAEQV+AL+ NPQV+ARLARSLDRWRKY PAL+E M A Sbjct: 823 SFCSGNPAQFHAADGSGYAFWAEQVLALDAINPQVSARLARSLDRWRKYVPALREAMHDA 882 Query: 875 LQQVAATPKLSRDVAEVITKALA 897 L++VAA P LSRDV E++ KALA Sbjct: 883 LKRVAAHPSLSRDVREIVGKALA 905 >PA3083 [E] COG0308 Aminopeptidase N Pae Pseudomonas aeruginosa Length = 885 Score = 909 bits (2350), Expect = 0.0, Method: Compositional matrix adjust. Identities = 479/904 (52%), Positives = 608/904 (67%), Gaps = 26/904 (2%) Query: 1 MRTDTPQTIYRKDYAAPNYLADTVEMGFDLDPADTHVATRITLTRNP--AAKGRDLILFG 58 MRT+ P+ I+ KDY AP+YL D + F+L + V + L RNP A L+L G Sbjct: 1 MRTEQPKVIHLKDYQAPDYLIDETHLKFELFEDHSLVHAELKLRRNPERGAGLPPLLLHG 60 Query: 59 EELELVALRLNGKTLSQAKGDFRIAGGVLTIPAAPAKVTLEIETLVHPDRNTSLMGLYVS 118 ++LEL+AL L+G+ L D+++ L + A+ L +HP+ NT+L GLY S Sbjct: 61 QQLELLALELDGQAL--GADDYQLDDEQLGVQPRQAEFVLRSTVRIHPESNTALEGLYKS 118 Query: 119 NGNFFTQCEAEGFRKITYFPDRPDVMAKFTVMLRADKARYPVLLSNGNLIEEGELPDGRH 178 F TQCEAEGFRKITY+ DRPDVM++FT + A++ RYPVLLSNGN + G +GRH Sbjct: 119 GKMFCTQCEAEGFRKITYYLDRPDVMSRFTTTVSAEQQRYPVLLSNGNPVASGSEGNGRH 178 Query: 179 YAKWEDPFKKPSYLFALVAGQLVCQEETVRLHSGRDALLQVWVEEGNLDKTQHAMESLKN 238 +A WEDPFKKP+YLFALVAG L C E++ R S RD L+++VE N+DK QHAM+SLK Sbjct: 179 WATWEDPFKKPAYLFALVAGDLWCVEDSFRTMSQRDVALRIYVEPENIDKVQHAMDSLKK 238 Query: 239 SITWDVERFGLDLDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPRIATDVDFANIE 298 S+ WD E +G + DLD FMIVAV DFNMGAMENKGLNIFN+ VLA ATD +E Sbjct: 239 SMRWDEEVYGREYDLDIFMIVAVNDFNMGAMENKGLNIFNSSCVLARAETATDAAHQRVE 298 Query: 299 AVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMIGSDSGRAVKRIDDVRVL 358 VV HEYFHNW+GNRVTCRDWFQLSLKEG TVFRD EFSADM + R VKR++DV L Sbjct: 299 GVVAHEYFHNWSGNRVTCRDWFQLSLKEGFTVFRDSEFSADM----NSRTVKRVEDVAFL 354 Query: 359 RQAQFPEDAGPMAHPVRPDSFVEINNFYTVTVYEKGAEVVRMYQTLLGRDGFRKGMDLYF 418 R QF EDAGPMAHPVRPDSF+EI+NFYT+TVYEKG+EVVRM TLLG +GFRKG DLYF Sbjct: 355 RTNQFAEDAGPMAHPVRPDSFIEISNFYTLTVYEKGSEVVRMIHTLLGAEGFRKGSDLYF 414 Query: 419 KRHDGQAVTCDDFRAAMADANGRDLSQFERWYSQAGTPLVQASADYDAKRKTLTLTLEQS 478 +RHDGQAVTCDDF AM DANG DL+QF+RWYSQ+GTP + +YDA + TLT+ QS Sbjct: 415 QRHDGQAVTCDDFVKAMEDANGVDLTQFKRWYSQSGTPRLAVEGEYDAAARRYTLTVRQS 474 Query: 479 CPATPGQKKKQPFHIPVAVGLLDAQGRDLALTLQGEKKAGATTRVLELTKAKQSFTFINV 538 CP TPGQ K+PF IP+ +GLLD QG +L L L+GE A RVL +T+A+Q F F+ V Sbjct: 475 CPPTPGQPSKEPFVIPLELGLLDGQGHELPLRLEGEAVAQGGNRVLAVTEAEQRFVFVEV 534 Query: 539 DEKPVPSLLRGFSAPVVLQYDYSDAELAFLMAHDSDAFNRWEAGQRLATRRLLNLTVAVQ 598 E+P+PSLLRGFSAPV L + YS +L FLM HDSD FNRWEAGQ+L+ + L L Sbjct: 535 PEQPLPSLLRGFSAPVKLSFPYSRDQLLFLMQHDSDGFNRWEAGQQLSVQVLQELI---- 590 Query: 599 AARQSGHVVAVDTVLNNIEHDGALADALRATLKDESLDPAFRELVLTLPSETMIAEQMEV 658 Q G + +D L +A R L DE+LD A +L+LPSE + E EV Sbjct: 591 GQHQRGEQLVLDP---------RLIEAYRTLLADEALDQAMVAEMLSLPSEAYLTEISEV 641 Query: 659 IDPHAIHVARQFLRRSLARELRDDLLAVYHAHQTPG---AYSPDAASAGHRALKNVALSY 715 D AIH AR+F R+ + L + L Y A++ AY +A+ R+L+N+ALSY Sbjct: 642 ADVDAIHAAREFARQRIGEALFEPLWQRYQANRKISRDTAYLAEASHIARRSLQNIALSY 701 Query: 716 LAELDDEEAMALAQQQDQDANNMTDRLAALSAVLNSAAPG-KSEALQRFYAEFEQEALVI 774 L+ EE +A +Q + +NMT+RL AL+ ++NS K +AL F F+ + LV+ Sbjct: 702 LSLSGREEILAACLEQYEGCDNMTERLTALAVLVNSGFEAEKGKALAMFADYFKDDPLVM 761 Query: 775 DKWFTLQA-TARNADVNTVRTLTEHPAFTLKNPNRARSLIFSFCNGNPSAFHALDGNGYA 833 D+WF++QA + + V+ L +HPAFTLKNPN+ R+LI +F N N FH DG GY Sbjct: 762 DQWFSVQAGSPLPGGLERVQELMQHPAFTLKNPNKVRALIGAFANQNLVNFHRPDGAGYR 821 Query: 834 FWAEQVIALNGSNPQVAARLARSLDRWRKYTPALQEKMRLALQQVAATPKLSRDVAEVIT 893 F A+QVI LN NPQ+A+RL L RWRKY A Q MR L+++ A+ +LS DV EV++ Sbjct: 822 FLADQVIVLNALNPQIASRLLVPLTRWRKYDEARQALMRGELERILASGELSSDVYEVVS 881 Query: 894 KALA 897 K+LA Sbjct: 882 KSLA 885 >YPO1414 [E] COG0308 Aminopeptidase N Ype Yersinia pestis Length = 871 Score = 867 bits (2240), Expect = 0.0, Method: Compositional matrix adjust. Identities = 466/896 (52%), Positives = 580/896 (64%), Gaps = 28/896 (3%) Query: 3 TDTPQTIYRKDYAAPNYLADTVEMGFDLDPADTHVATRITLTRNPAAKGRDLILFGEELE 62 T PQ YR DY AP+Y +++ F LD T V T ++ + LIL GE+L Sbjct: 2 TQQPQAKYRHDYRAPDYTITDIDLDFALDAQKTTV-TAVSKVKRQGTDVTPLILNGEDLT 60 Query: 63 LVALRLNGKTLSQAKGDFRIAGGVLTIPAAPAKVTLEIETLVHPDRNTSLMGLYVSNGNF 122 L+++ ++G QA +R L I PA TL I +HP N++L GLY+S Sbjct: 61 LISVSVDG----QAWPHYRQQDNTLVIEQLPADFTLTIVNDIHPATNSALEGLYLSGEAL 116 Query: 123 FTQCEAEGFRKITYFPDRPDVMAKFTVMLRADKARYPVLLSNGNLIEEGELPDGRHYAKW 182 TQCEAEGFR ITY+ DRPDV+A+FT + ADK+RYP LLSNGN + +GEL DGRH+ KW Sbjct: 117 CTQCEAEGFRHITYYLDRPDVLARFTTRIVADKSRYPYLLSNGNRVGQGELDDGRHWVKW 176 Query: 183 EDPFKKPSYLFALVAGQLVCQEETVRLHSGRDALLQVWVEEGNLDKTQHAMESLKNSITW 242 EDPF KPSYLFALVAG ++ SGR+ L+++V+ GNLD+ AM SLKNS+ W Sbjct: 177 EDPFPKPSYLFALVAGDFDVLQDKFITRSGREVALEIFVDRGNLDRADWAMTSLKNSMKW 236 Query: 243 DVERFGLDLDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPRIATDVDFANIEAVVG 302 D RFGL+ DLD +MIVAV FNMGAMENKGLN+FN+KYVLA ATD D+ NIEAV+G Sbjct: 237 DETRFGLEYDLDIYMIVAVDFFNMGAMENKGLNVFNSKYVLAKAETATDKDYLNIEAVIG 296 Query: 303 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMIGSDSGRAVKRIDDVRVLRQAQ 362 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFS+D+ R+V RI++VRV+R AQ Sbjct: 297 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL----GSRSVNRIENVRVMRAAQ 352 Query: 363 FPEDAGPMAHPVRPDSFVEINNFYTVTVYEKGAEVVRMYQTLLGRDGFRKGMDLYFKRHD 422 F EDA PMAH +RPD +E+NNFYT+TVYEKG+EV+RM TLLG F+ GM LYF+RHD Sbjct: 353 FAEDASPMAHAIRPDKVIEMNNFYTLTVYEKGSEVIRMMHTLLGEQQFQAGMRLYFERHD 412 Query: 423 GQAVTCDDFRAAMADANGRDLSQFERWYSQAGTPLVQASADYDAKRKTLTLTLEQSCPAT 482 G A TCDDF AM D + DLS F RWYSQ+GTPL+ DYD +++ L + Q T Sbjct: 413 GSAATCDDFVQAMEDVSNVDLSLFRRWYSQSGTPLLTVHDDYDVEKQQYHLFVSQKTLPT 472 Query: 483 PGQKKKQPFHIPVAVGLLDAQGRDLALTLQGEKKAGATTRVLELTKAKQSFTFINVDEKP 542 Q +K P HIP+ + L D++G + L G VL +T+A+Q+FTF NV +KP Sbjct: 473 ADQPEKLPLHIPLDIELYDSKGNVIPLQHNGL----PVHHVLNVTEAEQTFTFDNVAQKP 528 Query: 543 VPSLLRGFSAPVVLQYDYSDAELAFLMAHDSDAFNRWEAGQRLATRRLLNLTVAVQAARQ 602 +PSLLR FSAPV L Y YSD +L FLM H + F+RW+A Q L + L VA +Q Sbjct: 529 IPSLLREFSAPVKLDYPYSDQQLTFLMQHARNEFSRWDAAQSLLA-TYIKLNVAKYQQQQ 587 Query: 603 SGHVVAVDTVLNNIEHDGALADALRATLKDESLDPAFRELVLTLPSETMIAEQMEVIDPH 662 + A +ADA RA L DE LDPA +LTLPSE +AE IDP Sbjct: 588 PLSLPA------------HVADAFRAILLDEHLDPALAAQILTLPSENEMAELFTTIDPQ 635 Query: 663 AIHVARQFLRRSLARELRDDLLAVYHAHQTPGAYSPDAASAGHRALKNVALSYLAELDDE 722 AI + + R LA+EL D+LLAVY A+ TP Y + RAL+N L+YLA D+E Sbjct: 636 AISTVHEAITRCLAQELSDELLAVYVANMTP-VYRIEHGDIAKRALRNTCLNYLAFGDEE 694 Query: 723 EAMALAQQQDQDANNMTDRLAALSAVLNSAAPGKSEALQRFYAEFEQEALVIDKWFTLQA 782 A L Q A+NMTD LAAL+A + + P + E L F + + LV+DKWF LQA Sbjct: 695 FANKLVSSQYHQADNMTDSLAALAAAVAAQLPCRDELLAAFDVRWNHDGLVMDKWFALQA 754 Query: 783 TARNADVNT-VRTLTEHPAFTLKNPNRARSLIFSFCNGNPSAFHALDGNGYAFWAEQVIA 841 T+ A+V VRTL +HPAF+L NPNR RSLI SF +GNP+AFHA DG+GY F E + Sbjct: 755 TSPAANVLVQVRTLLKHPAFSLSNPNRTRSLIGSFASGNPAAFHAADGSGYQFLVEILSD 814 Query: 842 LNGSNPQVAARLARSLDRWRKYTPALQEKMRLALQQVAATPKLSRDVAEVITKALA 897 LN NPQVAARL L R ++Y Q MR AL+Q+ LS D+ E ITKALA Sbjct: 815 LNTRNPQVAARLIEPLIRLKRYDAGRQALMRKALEQLKTLDNLSGDLYEKITKALA 870 >ECs1015 [E] COG0308 Aminopeptidase N Ecs Escherichia coli O157:H7 Length = 870 Score = 859 bits (2219), Expect = 0.0, Method: Compositional matrix adjust. Identities = 460/897 (51%), Positives = 587/897 (65%), Gaps = 30/897 (3%) Query: 3 TDTPQTIYRKDYAAPNYLADTVEMGFDLDPADTHVATRITLTRNPAAKGRDLILFGEELE 62 T PQ YR DY AP+Y +++ FDLD T V T ++ A L L GE+L+ Sbjct: 2 TQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKT-VVTAVSQAVRHGASDAPLCLNGEDLK 60 Query: 63 LVALRLNGKTLSQAKGDFRIAGGVLTIPAAPAKVTLEIETLVHPDRNTSLMGLYVSNGNF 122 LV++ +N + + K + G L I P + TL+I + P NT+L GLY S Sbjct: 61 LVSVHINDEPWTAWKEE----EGALVISNLPERFTLKIINEISPAANTALEGLYQSGDAL 116 Query: 123 FTQCEAEGFRKITYFPDRPDVMAKFTVMLRADKARYPVLLSNGNLIEEGELPDGRHYAKW 182 TQCEAEGFR ITY+ DRPDV+A+FT + ADK +YP LLSNGN + +GEL +GRH+ +W Sbjct: 117 CTQCEAEGFRHITYYLDRPDVLARFTTKIIADKTKYPFLLSNGNRVAQGELENGRHWVQW 176 Query: 183 EDPFKKPSYLFALVAGQLVCQEETVRLHSGRDALLQVWVEEGNLDKTQHAMESLKNSITW 242 +DPF KP YLFALVAG +T SGR+ L+++V+ GNLD+ AM SLKNS+ W Sbjct: 177 QDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKW 236 Query: 243 DVERFGLDLDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPRIATDVDFANIEAVVG 302 D ERFGL+ DLD +MIVAV FNMGAMENKGLNIFN+KYVLA ATD D+ +IE V+G Sbjct: 237 DEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIG 296 Query: 303 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMIGSDSGRAVKRIDDVRVLRQAQ 362 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFS+D+ RAV RI++VR +R Q Sbjct: 297 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL----GSRAVNRINNVRTMRGLQ 352 Query: 363 FPEDAGPMAHPVRPDSFVEINNFYTVTVYEKGAEVVRMYQTLLGRDGFRKGMDLYFKRHD 422 F EDA PMAHP+RPD +E+NNFYT+TVYEKGAEV+RM TLLG + F+KGM LYF+RHD Sbjct: 353 FAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGMQLYFERHD 412 Query: 423 GQAVTCDDFRAAMADANGRDLSQFERWYSQAGTPLVQASADYDAKRKTLTLTLEQSCPAT 482 G A TCDDF AM DA+ DLS F RWYSQ+GTP+V DY+ + + TLT+ Q PAT Sbjct: 413 GSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPVVTVKDDYNPETEQYTLTISQRTPAT 472 Query: 483 PGQKKKQPFHIPVAVGLLDAQGRDLALTLQGEKKAGATTRVLELTKAKQSFTFINVDEKP 542 P Q +KQP HIP A+ L D +G+ + L +K VL +T+A+Q+F F NV +P Sbjct: 473 PDQAEKQPLHIPFAIELYDNEGKVIPL----QKGGHPVNSVLNVTQAEQTFVFDNVYFQP 528 Query: 543 VPSLLRGFSAPVVLQYDYSDAELAFLMAHDSDAFNRWEAGQR-LATRRLLNLTVAVQAAR 601 VP+LL FSAPV L+Y +SD +L FLM H + F+RW+A Q LAT LN+ A Sbjct: 529 VPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWDAAQSLLATYIKLNV-----ARH 583 Query: 602 QSGHVVAVDTVLNNIEHDGALADALRATLKDESLDPAFRELVLTLPSETMIAEQMEVIDP 661 Q G +++ +ADA RA L DE +DPA +LTLPS +AE ++IDP Sbjct: 584 QQGQPLSLPV---------HVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDP 634 Query: 662 HAIHVARQFLRRSLARELRDDLLAVYHAHQTPGAYSPDAASAGHRALKNVALSYLAELDD 721 AI R+ L R+LA EL D+LLA+Y+A+ Y + R L+N L +LA + Sbjct: 635 IAIAEVREALTRTLATELADELLAIYNANYQ-SEYRVEHEDIAKRTLRNACLRFLAFGET 693 Query: 722 EEAMALAQQQDQDANNMTDRLAALSAVLNSAAPGKSEALQRFYAEFEQEALVIDKWFTLQ 781 A L +Q +ANNMTD LAALSA + + P + +Q + ++ Q+ LV+DKWF LQ Sbjct: 694 HLADVLVSKQYHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWHQDGLVMDKWFILQ 753 Query: 782 ATARNADV-NTVRTLTEHPAFTLKNPNRARSLIFSFCNGNPSAFHALDGNGYAFWAEQVI 840 AT+ A+V TVR L +H +FT+ NPNR RSLI +F NP+AFHA DG+GY F E + Sbjct: 754 ATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAEDGSGYQFLVEMLT 813 Query: 841 ALNGSNPQVAARLARSLDRWRKYTPALQEKMRLALQQVAATPKLSRDVAEVITKALA 897 LN NPQVA+RL L R ++Y QEKMR AL+Q+ LS D+ E ITKALA Sbjct: 814 DLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLENLSGDLYEKITKALA 870 >pepN [E] COG0308 Aminopeptidase N Eco Escherichia coli K12 Length = 870 Score = 857 bits (2214), Expect = 0.0, Method: Compositional matrix adjust. Identities = 460/897 (51%), Positives = 586/897 (65%), Gaps = 30/897 (3%) Query: 3 TDTPQTIYRKDYAAPNYLADTVEMGFDLDPADTHVATRITLTRNPAAKGRDLILFGEELE 62 T PQ YR DY AP+Y +++ FDLD T V T ++ A L L GE+L+ Sbjct: 2 TQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKT-VVTAVSQAVRHGASDAPLRLNGEDLK 60 Query: 63 LVALRLNGKTLSQAKGDFRIAGGVLTIPAAPAKVTLEIETLVHPDRNTSLMGLYVSNGNF 122 LV++ +N + + K + G L I P + TL+I + P NT+L GLY S Sbjct: 61 LVSVHINDEPWTAWKEE----EGALVISNLPERFTLKIINEISPAANTALEGLYQSGDAL 116 Query: 123 FTQCEAEGFRKITYFPDRPDVMAKFTVMLRADKARYPVLLSNGNLIEEGELPDGRHYAKW 182 TQCEAEGFR ITY+ DRPDV+A+FT + ADK +YP LLSNGN + +GEL +GRH+ +W Sbjct: 117 CTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGNRVAQGELENGRHWVQW 176 Query: 183 EDPFKKPSYLFALVAGQLVCQEETVRLHSGRDALLQVWVEEGNLDKTQHAMESLKNSITW 242 +DPF KP YLFALVAG +T SGR+ L+++V+ GNLD+ AM SLKNS+ W Sbjct: 177 QDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKW 236 Query: 243 DVERFGLDLDLDRFMIVAVGDFNMGAMENKGLNIFNTKYVLANPRIATDVDFANIEAVVG 302 D ERFGL+ DLD +MIVAV FNMGAMENKGLNIFN+KYVLA ATD D+ +IE V+G Sbjct: 237 DEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIG 296 Query: 303 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMIGSDSGRAVKRIDDVRVLRQAQ 362 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFS+D+ RAV RI++VR +R Q Sbjct: 297 HEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL----GSRAVNRINNVRTMRGLQ 352 Query: 363 FPEDAGPMAHPVRPDSFVEINNFYTVTVYEKGAEVVRMYQTLLGRDGFRKGMDLYFKRHD 422 F EDA PMAHP+RPD +E+NNFYT+TVYEKGAEV+RM TLLG + F+KGM LYF+RHD Sbjct: 353 FAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENFQKGMQLYFERHD 412 Query: 423 GQAVTCDDFRAAMADANGRDLSQFERWYSQAGTPLVQASADYDAKRKTLTLTLEQSCPAT 482 G A TCDDF AM DA+ DLS F RWYSQ+GTP+V DY+ + + TLT+ Q PAT Sbjct: 413 GSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTVKDDYNPETEQYTLTISQRTPAT 472 Query: 483 PGQKKKQPFHIPVAVGLLDAQGRDLALTLQGEKKAGATTRVLELTKAKQSFTFINVDEKP 542 P Q +KQP HIP A+ L D +G+ + L +K VL +T+A+Q+F F NV +P Sbjct: 473 PDQAEKQPLHIPFAIELYDNEGKVIPL----QKGGHPVNSVLNVTQAEQTFVFDNVYFQP 528 Query: 543 VPSLLRGFSAPVVLQYDYSDAELAFLMAHDSDAFNRWEAGQR-LATRRLLNLTVAVQAAR 601 VP+LL FSAPV L+Y +SD +L FLM H + F+RW+A Q LAT LN+ A Sbjct: 529 VPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWDAAQSLLATYIKLNV-----ARH 583 Query: 602 QSGHVVAVDTVLNNIEHDGALADALRATLKDESLDPAFRELVLTLPSETMIAEQMEVIDP 661 Q G +++ +ADA RA L DE +DPA +LTLPS +AE ++IDP Sbjct: 584 QQGQPLSLPV---------HVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDP 634 Query: 662 HAIHVARQFLRRSLARELRDDLLAVYHAHQTPGAYSPDAASAGHRALKNVALSYLAELDD 721 AI R+ L R+LA EL D+LLA+Y+A+ Y + R L+N L +LA + Sbjct: 635 IAIAEVREALTRTLATELADELLAIYNANYQ-SEYRVEHEDIAKRTLRNACLRFLAFGET 693 Query: 722 EEAMALAQQQDQDANNMTDRLAALSAVLNSAAPGKSEALQRFYAEFEQEALVIDKWFTLQ 781 A L +Q +ANNMTD LAALSA + + P + +Q + ++ Q LV+DKWF LQ Sbjct: 694 HLADVLVSKQFHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWHQNGLVMDKWFILQ 753 Query: 782 ATARNADV-NTVRTLTEHPAFTLKNPNRARSLIFSFCNGNPSAFHALDGNGYAFWAEQVI 840 AT+ A+V TVR L +H +FT+ NPNR RSLI +F NP+AFHA DG+GY F E + Sbjct: 754 ATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAEDGSGYLFLVEMLT 813 Query: 841 ALNGSNPQVAARLARSLDRWRKYTPALQEKMRLALQQVAATPKLSRDVAEVITKALA 897 LN NPQVA+RL L R ++Y QEKMR AL+Q+ LS D+ E ITKALA Sbjct: 814 DLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLENLSGDLYEKITKALA 870