BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0008.0005.p (318 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2126 [G] COG0158 Fructose-1,6-bisphosphatase Rso Ralstonia so... 471 e-133 PA5110 [G] COG0158 Fructose-1,6-bisphosphatase Pae Pseudomonas a... 433 e-121 CC1385 Non COG 319 6e-87 NMB1060 [G] COG0158 Fructose-1,6-bisphosphatase Nme Neisseria me... 318 8e-87 NMA1259 [G] COG0158 Fructose-1,6-bisphosphatase NmA Neisseria me... 314 2e-85 >RSc2126 [G] COG0158 Fructose-1,6-bisphosphatase Rso Ralstonia solanacearum Length = 338 Score = 471 bits (1213), Expect = e-133, Method: Compositional matrix adjust. Identities = 222/287 (77%), Positives = 253/287 (88%) Query: 1 MKRISLTQHLIEQQRLHNKIPSELRLLIEVVGRACKSISHAVGKGALGEVLGSAGSENVQ 60 MKRI+LT++LIE+QR HN IP+ELRLL+EVV RACK+ISH+V KGAL VLGSAG+ NVQ Sbjct: 1 MKRINLTRYLIEEQREHNTIPAELRLLLEVVARACKAISHSVNKGALAGVLGSAGTGNVQ 60 Query: 61 GEVQKKLDVISNEILLEANEWGGHLAAMASEEMETIHRIPNRYPKGEYLLMFDPLDGSSN 120 GE Q+KLDVI+NE+LLEANE+GG+LAAMASEEME+ + IP+RYPKGEYLL+FDPLDGSSN Sbjct: 61 GETQQKLDVIANEVLLEANEYGGNLAAMASEEMESFYEIPHRYPKGEYLLLFDPLDGSSN 120 Query: 121 IDVNVSIGTIFSVLKAPEGMTEPSEQDFMQPGTKQVAAGYAVYGPQTVLVLTTGDGVHCF 180 IDVNVSIGTIFSVL P+ +E DFMQPG +QVAAGYAVYGPQT LVLT G+GVH F Sbjct: 121 IDVNVSIGTIFSVLHMPKPGQTVTEADFMQPGVRQVAAGYAVYGPQTTLVLTVGNGVHMF 180 Query: 181 TLDREMGAWVLTQKDIKIPEDTKEFAINASNQRHWFPPVTRYVDEMLAGSTGPRGKDFNM 240 TLDRE+G+++LT +D+KIP DTKEFAIN SN RHW PPV RY+DE LAG+ GPRGKDFNM Sbjct: 181 TLDREVGSFILTNRDVKIPADTKEFAINMSNMRHWAPPVRRYIDECLAGTEGPRGKDFNM 240 Query: 241 RWIASMVADVHRILNRGGIFMYPADAREPGKPGKLRLMYEANPMAFM 287 RWIASMVADVHRIL RGGIFMYP D REPGK GKLRLMYEANPMAF+ Sbjct: 241 RWIASMVADVHRILTRGGIFMYPWDKREPGKAGKLRLMYEANPMAFL 287 >PA5110 [G] COG0158 Fructose-1,6-bisphosphatase Pae Pseudomonas aeruginosa Length = 336 Score = 433 bits (1114), Expect = e-121, Method: Compositional matrix adjust. Identities = 208/291 (71%), Positives = 243/291 (83%), Gaps = 5/291 (1%) Query: 1 MKRISLTQHLIEQQRLHNKIPSELRLLIEVVGRACKSISHAVGKGALGEVLGSAGSENVQ 60 M R++L+++LIEQ R HN P++LR LIEVV RACK ISHAV KGALG VLGS G+ENVQ Sbjct: 1 MSRVTLSRYLIEQTRSHNT-PADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQ 59 Query: 61 GEVQKKLDVISNEILLEANEWGGHLAAMASEEMETIHRIPNRYPKGEYLLMFDPLDGSSN 120 GEVQKKLDV+SNEILLEANEW G+LA MASEEM+ ++IP RYPKG YLL+FDPLDGSSN Sbjct: 60 GEVQKKLDVMSNEILLEANEWAGNLAGMASEEMDHPYQIPGRYPKGAYLLVFDPLDGSSN 119 Query: 121 IDVNVSIGTIFSVLKAPEGMTEPS----EQDFMQPGTKQVAAGYAVYGPQTVLVLTTGDG 176 IDVNVS+GTIFSVL+ P + E+ F+QPGT QVAAGYA+YGPQT+L+LT G+G Sbjct: 120 IDVNVSVGTIFSVLRCPNEYLNQNDTLREEAFLQPGTTQVAAGYAIYGPQTMLMLTLGNG 179 Query: 177 VHCFTLDREMGAWVLTQKDIKIPEDTKEFAINASNQRHWFPPVTRYVDEMLAGSTGPRGK 236 V FTLDRE+G++VLT +I +PE T EFAIN SNQRHW PV RYV+E+LAG GP GK Sbjct: 180 VKGFTLDRELGSFVLTHDNISVPESTAEFAINMSNQRHWEAPVKRYVEELLAGKEGPLGK 239 Query: 237 DFNMRWIASMVADVHRILNRGGIFMYPADAREPGKPGKLRLMYEANPMAFM 287 ++NMRWIASMVADVHRIL RGG+FMYP DAREP KPGKLRLMYEANPM+F+ Sbjct: 240 NYNMRWIASMVADVHRILTRGGVFMYPRDAREPEKPGKLRLMYEANPMSFI 290 >CC1385 Non COG Length = 336 Score = 319 bits (817), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 162/269 (60%), Positives = 194/269 (72%), Gaps = 5/269 (1%) Query: 22 SELRLLIEVVGRACKSISHAVGKGALGEVLGSAGSENVQGEVQKKLDVISNEILLEANEW 81 + L+ ++ + C IS V GAL LG+AGS NVQ E QKKLDVI+N++L +A + Sbjct: 29 AALKDVVLTIAETCAQISRVVASGALSGSLGAAGSTNVQDEEQKKLDVITNDMLSDALKA 88 Query: 82 GGHLAAMASEEMETIHRIPNRYPKGEYLLMFDPLDGSSNIDVNVSIGTIFSVLKAPEGMT 141 G +A +ASEE+E + G YL+ FDPLDGSSNIDVNVS+GTIFSVL AP G Sbjct: 89 CGPVAGLASEELEEVEPTGR---VGGYLVTFDPLDGSSNIDVNVSVGTIFSVLPAPAGHA 145 Query: 142 EPSEQDFMQPGTKQVAAGYAVYGPQTVLVLTTGDGVHCFTLDREMGAWVLTQKDIKIPED 201 P+E DF+QPG QVAAGYAVYGPQT+LV+T GV+ FTL + G W+LT D+ I D Sbjct: 146 -PTEGDFLQPGRNQVAAGYAVYGPQTMLVVTLSGGVNGFTLSAD-GRWLLTHPDLAIKPD 203 Query: 202 TKEFAINASNQRHWFPPVTRYVDEMLAGSTGPRGKDFNMRWIASMVADVHRILNRGGIFM 261 T EFAIN SNQRHW P V RY+D L G G RGK+FNMRW+ASMVADVHRI+ RGG+FM Sbjct: 204 TAEFAINMSNQRHWAPAVRRYIDGCLQGKDGARGKNFNMRWVASMVADVHRIMMRGGVFM 263 Query: 262 YPADAREPGKPGKLRLMYEANPMAFMXWR 290 YP DAREP KPGKLRLMYEANPM+ + R Sbjct: 264 YPWDAREPDKPGKLRLMYEANPMSLLAER 292 >NMB1060 [G] COG0158 Fructose-1,6-bisphosphatase Nme Neisseria meningitidis MC58 Length = 324 Score = 318 bits (816), Expect = 8e-87, Method: Compositional matrix adjust. Identities = 158/283 (55%), Positives = 208/283 (73%), Gaps = 7/283 (2%) Query: 5 SLTQHLIEQQRLHNKIPSELRLLIEVVGRACKSISHAVGKGALGEVLGSAGSENVQGEVQ 64 +LT+ L E + N++P L ++ V AC I+ V GAL VLG AG+ N+QGE Q Sbjct: 3 TLTRFLPEHLQ-QNQLPEALGGVLLSVVSACTEINAKVRLGALAGVLGMAGTGNIQGEDQ 61 Query: 65 KKLDVISNEILLEANEWGGHLAAMASEEMETIHRIPNRYPKGEYLLMFDPLDGSSNIDVN 124 KKLDVI+N I+++ + +A +ASEE +T N G YL++FDPLDGSSNIDVN Sbjct: 62 KKLDVIANNIMIDTLKANSAVAGLASEEEDTF---VNAGENGRYLVLFDPLDGSSNIDVN 118 Query: 125 VSIGTIFSVLKAPEGMTEPSEQDFMQPGTKQVAAGYAVYGPQTVLVLTTGDGVHCFTLDR 184 +S+GTIFS+L+ PEG + + F+Q G +Q+AAGY +YGPQT LV T G GV+ FTL+ Sbjct: 119 ISVGTIFSILEKPEGAL--ATESFLQTGRQQLAAGYVLYGPQTQLVFTFGHGVYMFTLNA 176 Query: 185 EMGAWVLTQKDIKIPEDTKEFAINASNQRHWFPPVTRYVDEMLAGSTGPRGKDFNMRWIA 244 E +VLT+++ K+PE TKEFAIN SN+RHW PPV +Y+DE+LAG TG RGK++NMRW+A Sbjct: 177 E-NEFVLTKENPKVPESTKEFAINMSNRRHWLPPVQQYIDELLAGETGTRGKNYNMRWVA 235 Query: 245 SMVADVHRILNRGGIFMYPADAREPGKPGKLRLMYEANPMAFM 287 SMVA++HRIL RGG+FMYP D R+P KPGKLRLMYEANPM+ + Sbjct: 236 SMVAEIHRILMRGGVFMYPQDKRDPAKPGKLRLMYEANPMSLI 278 >NMA1259 [G] COG0158 Fructose-1,6-bisphosphatase NmA Neisseria meningitidis Z2491 Length = 324 Score = 314 bits (804), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 157/283 (55%), Positives = 207/283 (73%), Gaps = 7/283 (2%) Query: 5 SLTQHLIEQQRLHNKIPSELRLLIEVVGRACKSISHAVGKGALGEVLGSAGSENVQGEVQ 64 +LT+ L E + N++P L ++ V AC I+ V GAL VLG AG+ N+QGE Q Sbjct: 3 TLTRFLPEHLQ-QNQLPEALGGVLLSVVSACTEINAKVRLGALAGVLGMAGTGNIQGEDQ 61 Query: 65 KKLDVISNEILLEANEWGGHLAAMASEEMETIHRIPNRYPKGEYLLMFDPLDGSSNIDVN 124 KKLDVI+N I+++ + +A +ASEE ++ + G YL++FDPLDGSSNIDVN Sbjct: 62 KKLDVIANNIMIDTLKANPAVAGLASEEEDSF---VSAGENGRYLVLFDPLDGSSNIDVN 118 Query: 125 VSIGTIFSVLKAPEGMTEPSEQDFMQPGTKQVAAGYAVYGPQTVLVLTTGDGVHCFTLDR 184 +S+GTIFS+L+ PEG + + F+Q G +Q+AAGY +YGPQT LV T G GV+ FTL+ Sbjct: 119 ISVGTIFSILEKPEGAL--ATESFLQTGRQQLAAGYVLYGPQTQLVFTFGHGVYMFTLNA 176 Query: 185 EMGAWVLTQKDIKIPEDTKEFAINASNQRHWFPPVTRYVDEMLAGSTGPRGKDFNMRWIA 244 E +VLT++ K+PE TKEFAIN SN+RHW PPV +Y+DE+LAG TG RGK++NMRW+A Sbjct: 177 E-NEFVLTKEKPKVPESTKEFAINMSNRRHWLPPVQQYIDELLAGETGTRGKNYNMRWVA 235 Query: 245 SMVADVHRILNRGGIFMYPADAREPGKPGKLRLMYEANPMAFM 287 SMVA++HRIL RGG+FMYP D R+P KPGKLRLMYEANPMA + Sbjct: 236 SMVAEIHRILMRGGVFMYPQDKRDPSKPGKLRLMYEANPMALI 278