BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0134.p (184 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value L189881 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthas... 211 5e-55 PA3968 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase... 203 2e-52 NMB1496 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthas... 199 3e-51 ymfC [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase a... 194 6e-50 ECs1607 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthas... 193 2e-49 >L189881 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Lla Lactococcus lactis Length = 185 Score = 211 bits (538), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 100/175 (57%), Positives = 129/175 (73%), Gaps = 2/175 (1%) Query: 1 LILFNKPFGVMSQFSAHPERQTLADYLDLPDIYPAGRLDADSEGLLLLTDDGKLQHAIAH 60 +ILFNKP+ V+++F+ R+TL DY+ +P++Y AGRLD DSEGLLLLTDDGKL H + Sbjct: 9 IILFNKPYDVLTKFTDGEGRKTLKDYIKIPNVYAAGRLDKDSEGLLLLTDDGKLNHLLTD 68 Query: 61 PRRKQPKTYLAQVEGLATPEALQRLRNPLDLGDFVTQPGEARLIQEPAWMWPRTPPIRQR 120 P+ K KTYL QVEG +PEA Q+L+ L L D T P + +LI EP W+W RTPPIR+R Sbjct: 69 PKSKSYKTYLVQVEGEFSPEAAQKLQKGLLLKDGKTLPAKVKLIDEPDWLWERTPPIRER 128 Query: 121 ANQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPLMPGEWR 175 PTSW+ ++I EGKNRQ+RRMTAAVG PTLRL+R +IG +SL L GE++ Sbjct: 129 KAIPTSWVEISIKEGKNRQIRRMTAAVGFPTLRLIRWSIGQYSLGN--LKSGEYK 181 >PA3968 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Pae Pseudomonas aeruginosa Length = 189 Score = 203 bits (517), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 111/183 (60%), Positives = 131/183 (71%), Gaps = 4/183 (2%) Query: 1 LILFNKPFGVMSQFSAHPERQTLADYLDLPDIYPAGRLDADSEGLLLLTDDGKLQHAIAH 60 L+LFNKPF V++QF+ R TL D++ +P +YPAGRLD DSEGLLLLT+DG+LQ IA Sbjct: 11 LLLFNKPFDVLTQFNDEQGRSTLKDFIPVPGVYPAGRLDRDSEGLLLLTNDGRLQARIAD 70 Query: 61 PRRKQPKTYLAQVEGLATPEALQRLRNPLDLGDFVTQPGEARLIQEPAWMWPRTPPIRQR 120 PR K PKTY QVEG E L+RLR + L D T P EARL+ EP +W R PP+R R Sbjct: 71 PRHKLPKTYWVQVEGTPDEEQLRRLREGVTLNDGPTLPAEARLLDEPT-LWERVPPVRFR 129 Query: 121 ANQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPLMPGEWREVDPQ 180 + PT W+ L I EG+NRQVRRMTAAVGLPTLRLVR+ IGP+SL L GEWREV P Sbjct: 130 KSVPTHWLELVIREGRNRQVRRMTAAVGLPTLRLVRVRIGPWSLDGLGL--GEWREV-PA 186 Query: 181 ELD 183 LD Sbjct: 187 RLD 189 >NMB1496 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Nme Neisseria meningitidis MC58 Length = 186 Score = 199 bits (506), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 99/176 (56%), Positives = 121/176 (68%), Gaps = 2/176 (1%) Query: 1 LILFNKPFGVMSQFSAHPERQTLADYLDLPDIYPAGRLDADSEGLLLLTDDGKLQHAIAH 60 LI FNKP+GV+ QFS H + ++L D+++LP YPAGRLD DSEGLLLLTDDG+LQ I Sbjct: 4 LIAFNKPYGVICQFSPHEKHKSLKDFINLPGFYPAGRLDTDSEGLLLLTDDGRLQAQITD 63 Query: 61 PRRKQPKTYLAQVEGLATPEALQRLRNPLDLGDFVTQPGEARLIQ--EPAWMWPRTPPIR 118 P+ K PKTY AQ+EG+ L+ LR +DLG FVT+P R+++ E +W R PPIR Sbjct: 64 PKFKHPKTYWAQLEGVPDESRLESLRKGIDLGGFVTRPASIRILKHGEADSLWERIPPIR 123 Query: 119 QRANQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPLMPGEW 174 R P WI +TISEGKNRQVRRMTA G P LRL+R+A G L L PGEW Sbjct: 124 VRKTVPDFWIEITISEGKNRQVRRMTAKAGYPCLRLIRVASGRLKLFDLDLKPGEW 179 >ymfC [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Eco Escherichia coli K12 Length = 207 Score = 194 bits (494), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 95/177 (53%), Positives = 126/177 (71%), Gaps = 2/177 (1%) Query: 1 LILFNKPFGVMSQFSAHPERQTLADYLDLPDIYPAGRLDADSEGLLLLTDDGKLQHAIAH 60 +ILFNKP+ V+ QF+ R+TL +++ + +Y AGRLD DSEGLL+LT++G LQ + Sbjct: 31 VILFNKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQ 90 Query: 61 PRRKQPKTYLAQVEGLATPEALQRLRNPLDLGDFVTQPGEARLIQEPAWMWPRTPPIRQR 120 P ++ K Y QVEG+ T +AL+ LRN + L D T P A L+ EPAW+WPR PPIR+R Sbjct: 91 PGKRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRER 150 Query: 121 ANQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPLMPGEWREV 177 + PTSW+ +T+ EG+NRQVRRMTA VG PTLRL+R A+G +SL L GEWREV Sbjct: 151 KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDN--LANGEWREV 205 >ECs1607 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Ecs Escherichia coli O157:H7 Length = 217 Score = 193 bits (491), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 94/176 (53%), Positives = 125/176 (71%), Gaps = 2/176 (1%) Query: 1 LILFNKPFGVMSQFSAHPERQTLADYLDLPDIYPAGRLDADSEGLLLLTDDGKLQHAIAH 60 +ILFNKP+ V+ QF+ R+TL +++ + +Y AGRLD DSEGLL+LT++G LQ + Sbjct: 41 VILFNKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQ 100 Query: 61 PRRKQPKTYLAQVEGLATPEALQRLRNPLDLGDFVTQPGEARLIQEPAWMWPRTPPIRQR 120 P ++ K Y QVEG+ T +AL+ LRN + L D T P A L+ EPAW+WPR PPIR+R Sbjct: 101 PGKRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRER 160 Query: 121 ANQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPLMPGEWRE 176 + PTSW+ +T+ EG+NRQVRRMTA VG PTLRL+R A+G +SL L GEWRE Sbjct: 161 KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDN--LANGEWRE 214