BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0106.p (461 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2324 [GEPR] COG0477 Permeases of the major facilitator superf... 261 3e-69 Rv1634 [GEPR] COG0477 Permeases of the major facilitator superfa... 192 2e-48 MT1670 [GEPR] COG0477 Permeases of the major facilitator superfa... 192 2e-48 CC3078 [GEPR] COG0477 Permeases of the major facilitator superfa... 163 9e-40 SMc01217 [GEPR] COG0477 Permeases of the major facilitator super... 150 5e-36 >RSc2324 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 475 Score = 261 bits (667), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 192/461 (41%), Positives = 277/461 (60%), Gaps = 23/461 (4%) Query: 9 RAVALTGGVALYAINVHIVTTILPSVVRDIGGLAYYAWNVTLFVAASIVGSALTGKLMGA 68 R + L GVAL+AIN+++ TTILPSVV DIGG+A+YAWN TLF+ ASI G+A+ +++ Sbjct: 24 RVLVLAAGVALHAINLYLTTTILPSVVDDIGGVAFYAWNTTLFIVASITGAAVAAQVIQH 83 Query: 69 MGARATYLMALALFGSGALLCGSAGSMGWMLAGRAVQGIGGGLLAALAYALIPLVFEPRM 128 +G R YL+ +FG G+ LC A M +L GR +QG+GGG+L + Y L+ V + Sbjct: 84 LGPRGAYLLGAMVFGGGSALCALAPIMQVLLVGRVLQGLGGGVLLSAPYVLMRSVLPEPL 143 Query: 129 WPRAIALVSGMWGVSTLLGPAVGGLFAASGHWRVAFFA---LLPLLAAQAWLVWRQLGPA 185 WPRA+AL+SGMWG++TLLGPAVGG+FA WR+AF++ L+ L AA A +V + P Sbjct: 144 WPRALALLSGMWGIATLLGPAVGGIFAQYATWRLAFWSLVVLIALAAAAAVVVLKPAAPQ 203 Query: 186 TVRSASGPAQAVPQFLLGRIALLASSVLLVALAAQADDDWLASACVLAGVLLAVWMARID 245 R P + ++ LLA +V+ + A+ +D WL + ++A L + + R++ Sbjct: 204 AERPTPVPTR--------QLVLLAVAVVAASWASVSDSPWLGALGLIAAALTLLAIRRVE 255 Query: 246 LRHRANLLPHAAYRPRTVMGGVMACIALL-VMGSCVEIFLPYFLQGLHGYDPLGAGYATA 304 +R +LP AY RT + + ALL V +C EIF+P FLQ LHG PL AGY A Sbjct: 256 MRSSRRILPADAYTGRTALAALYGVSALLAVTVTCTEIFVPLFLQRLHGQSPLIAGYIAA 315 Query: 305 AMAAGWSLGSLGGSGLSGRAALRMIRLGPCMMTLGMALLAFLMP----AQWLPAGALADG 360 +AGW+LG++ + L + R IRL P LG+ +LA L+P + W+ Sbjct: 316 TASAGWTLGAILSAALRAASVTRAIRLAPWACALGLLVLAMLVPIGAGSAWM------TT 369 Query: 361 LIVLALGVTGLGIGMGWPHLVARALHAAQPGEENLTSSAITTVQLFAMALGAALAGLVAN 420 LI++AL + GLG+G+ WPHL R + AA + + S++I TVQL A ALGAAL G+V N Sbjct: 370 LIIVALTLVGLGVGVVWPHLGNRIMTAAPAEDHDRASASIVTVQLVATALGAALGGVVLN 429 Query: 421 QAGLGAGGAEATARAAWVLLALFTLAPALAIFVARSVTRDR 461 G + A + W+ L LF +AP A+ +A + R R Sbjct: 430 TLGAAGPAPDLGAASRWLFL-LFAVAPVGALVIAHTGLRTR 469 >Rv1634 [GEPR] COG0477 Permeases of the major facilitator superfamily Mtu Mycobacterium tuberculosis H37Rv Length = 471 Score = 192 bits (488), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 172/460 (37%), Positives = 247/460 (53%), Gaps = 22/460 (4%) Query: 10 AVALTGGVALYAINVHIVTTILPSVVRDIGGLAYYAWNVTLFVAASIVGSALTGKLMGAM 69 ++ L GGVALYA N + ++LPS + DIGG YAW TL++ S+V + ++ + Sbjct: 22 SIVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVTTLYLVGSVVAATTVNTMLLRV 81 Query: 70 GARATYLMALALFGSGALLCGSAGSMGWMLAGRAVQGIGGGLLAALAYALIPLVFEPRMW 129 GAR++YLM LA+FG +L+C +A SM ++AGR +QGI GGLLA L YALI +W Sbjct: 82 GARSSYLMGLAVFGLASLVCAAAPSMQILVAGRTLQGIAGGLLAGLGYALINSTLPKSLW 141 Query: 130 PRAIALVSGMWGVSTLLGPAVGGLFAASGHWRVAFFALLPLLAAQAWLVWRQL----GPA 185 R ALVS MWGV+TL+GPA GGLFA G WR AF + L A A LV L Sbjct: 142 TRGSALVSAMWGVATLIGPATGGLFAQLGLWRWAFGVMTLLTALMAMLVPVALGAGGVGP 201 Query: 186 TVRSASGPAQAVPQFLLGRIALLASSVLLVALAAQADDDWLASAC--VLAGVLLAVWMAR 243 + G VP + L + A ++ + AL ++L + A LL Sbjct: 202 GGETPVGSTHKVPVWSLLLMGAAALAISVAAL-----PNYLVQTAGLLAAAALLVAVFVV 256 Query: 244 IDLRHRANLLPHAAYRPRTVMGGVMACIALLVMGSCVEIFLPYFLQGLHGYDPLGAGYAT 303 +D R A +LP + + + + +++ ++ + V+ ++P F Q L P+ AG+ Sbjct: 257 VDWRIHAAVLPPSVFGSGP-LKWIYLTMSVQMIAAMVDTYVPLFGQRLGHLTPVAAGFLG 315 Query: 304 AAMAAGWSLGSLGGSGL-SGRAALRMIRLGPCMMTLGMALLAFLMPAQWLPAGALADGLI 362 AA+A GW++G + + L S R ++ P +M G+AL A A P G +A L Sbjct: 316 AALAVGWTVGEVASASLNSARVIGHVVAAAPLVMASGLALGAVTQRAD-APVGIIA--LW 372 Query: 363 VLALGVTGLGIGMGWPHLVARALHA-AQPGEENLTSSAITTVQLFAMALGAALAGLVANQ 421 LAL + G GIG+ WPHL RA+ + A P E + ++AI VQL + A GA LAG+V N Sbjct: 373 ALALLIIGTGIGIAWPHLTVRAMDSVADPAESSAAAAAINVVQLISGAFGAGLAGVVVNT 432 Query: 422 AGLGAGGAEATARAAWVLLALFTLAPALAIFVARSVTRDR 461 A GG A AR + +A LA A I ++ RDR Sbjct: 433 A---KGGEVAAARGLY--MAFTVLAAAGVIASYQATHRDR 467 >MT1670 [GEPR] COG0477 Permeases of the major facilitator superfamily MtC Mycobacterium tuberculosis CDC1551 Length = 471 Score = 192 bits (488), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 172/460 (37%), Positives = 247/460 (53%), Gaps = 22/460 (4%) Query: 10 AVALTGGVALYAINVHIVTTILPSVVRDIGGLAYYAWNVTLFVAASIVGSALTGKLMGAM 69 ++ L GGVALYA N + ++LPS + DIGG YAW TL++ S+V + ++ + Sbjct: 22 SIVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVTTLYLVGSVVAATTVNTMLLRV 81 Query: 70 GARATYLMALALFGSGALLCGSAGSMGWMLAGRAVQGIGGGLLAALAYALIPLVFEPRMW 129 GAR++YLM LA+FG +L+C +A SM ++AGR +QGI GGLLA L YALI +W Sbjct: 82 GARSSYLMGLAVFGLASLVCAAAPSMQILVAGRTLQGIAGGLLAGLGYALINSTLPKSLW 141 Query: 130 PRAIALVSGMWGVSTLLGPAVGGLFAASGHWRVAFFALLPLLAAQAWLVWRQL----GPA 185 R ALVS MWGV+TL+GPA GGLFA G WR AF + L A A LV L Sbjct: 142 TRGSALVSAMWGVATLIGPATGGLFAQLGLWRWAFGVMTLLTALMAMLVPVALGAGGVGP 201 Query: 186 TVRSASGPAQAVPQFLLGRIALLASSVLLVALAAQADDDWLASAC--VLAGVLLAVWMAR 243 + G VP + L + A ++ + AL ++L + A LL Sbjct: 202 GGETPVGSTHKVPVWSLLLMGAAALAISVAAL-----PNYLVQTAGLLAAAALLVAVFVV 256 Query: 244 IDLRHRANLLPHAAYRPRTVMGGVMACIALLVMGSCVEIFLPYFLQGLHGYDPLGAGYAT 303 +D R A +LP + + + + +++ ++ + V+ ++P F Q L P+ AG+ Sbjct: 257 VDWRIHAAVLPPSVFGSGP-LKWIYLTMSVQMIAAMVDTYVPLFGQRLGHLTPVAAGFLG 315 Query: 304 AAMAAGWSLGSLGGSGL-SGRAALRMIRLGPCMMTLGMALLAFLMPAQWLPAGALADGLI 362 AA+A GW++G + + L S R ++ P +M G+AL A A P G +A L Sbjct: 316 AALAVGWTVGEVASASLNSARVIGHVVAAAPLVMASGLALGAVTQRAD-APVGIIA--LW 372 Query: 363 VLALGVTGLGIGMGWPHLVARALHA-AQPGEENLTSSAITTVQLFAMALGAALAGLVANQ 421 LAL + G GIG+ WPHL RA+ + A P E + ++AI VQL + A GA LAG+V N Sbjct: 373 ALALLIIGTGIGIAWPHLTVRAMDSVADPAESSAAAAAINVVQLISGAFGAGLAGVVVNT 432 Query: 422 AGLGAGGAEATARAAWVLLALFTLAPALAIFVARSVTRDR 461 A GG A AR + +A LA A I ++ RDR Sbjct: 433 A---KGGEVAAARGLY--MAFTVLAAAGVIASYQATHRDR 467 >CC3078 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 462 Score = 163 bits (412), Expect = 9e-40, Method: Compositional matrix adjust. Identities = 145/424 (34%), Positives = 208/424 (49%), Gaps = 28/424 (6%) Query: 16 GVALYAINVHIVTTILPSVVRDIGGLAYYAWNVTLFVAASIVGSALTGKLMGAMGARATY 75 G+ L A + + TI+PSV ++IGG Y+ W+V ++ SIV A +GKL AMG RA Sbjct: 28 GIWLNAADTLVTATIMPSVAKEIGGYQYFGWSVAAYLTGSIVAGACSGKLSIAMGLRAAT 87 Query: 76 LMALALFGSGALLCGSAGSMGWMLAGRAVQGIGGGLLAALAYALIPLVFEPRMWPRAIAL 135 ++ ++ G + A + GR VQG+G G + AL Y I +F +WPR Sbjct: 88 AISGLVYAIGCAMSALAPEFITFIVGRLVQGLGAGAVVALCYVAISALFPQNLWPRVYGA 147 Query: 136 VSGMWGVSTLLGPAVGGLFAASGHWRVAF--FALLPLLAAQAWLVWRQLGPATVRSASGP 193 ++G+WG +TLLGPA+GGLFAA G WR F F + ++ A +V G P Sbjct: 148 IAGVWGAATLLGPALGGLFAAVGFWRGVFWMFVVQAVIFVGAVMVMLPGGKREEGGGRIP 207 Query: 194 AQAVPQFLLGRIALLASSVLLVALAAQADDDWLASACVLAGVLLAVWMARIDLRHRANLL 253 + ++ALL V L+ A LA + G++ V M + R + LL Sbjct: 208 SL--------QLALLVIGVSLIGGAGVVASPRLAVILAIGGMIGMVAMLAANTRTQDRLL 259 Query: 254 PHAAYRPRTVMG----GVMACIALLVMGSCVEIFLPYFLQGLHGYDPLGAGYATAAMAAG 309 P +A RT G + AC A ++ ++ P F+Q H PL AGY T A+AAG Sbjct: 260 PKSAADLRTATGLGLLTIFACEAAVI---GFTVYGPAFIQARHDASPLLAGYVTGAIAAG 316 Query: 310 WSLGSLGGSGLSGRAALRMIRLGPCMMTLGMALLAFLMPAQWLPAGALADGLIVLALGVT 369 W+ +L + R +RLG ++ LG AL AF +P L+ +L Sbjct: 317 WTACALIFGHVPAHKDGRFVRLGAGVIALGAALSAFAVP---------RGNLVETSLAFV 367 Query: 370 GLGIGMGWPH-LVARALHAAQPGEEN-LTSSAITTVQLFAMALGAALAGLVANQAGLGAG 427 LG G G H +AR A P EE + S A+ T QL A+G+A AG +AN G G Sbjct: 368 VLGAGFGLCHAFIARRTIAGAPAEEQAMASGAVPTSQLIGGAVGSAGAGAMANVLGFGHH 427 Query: 428 GAEA 431 G +A Sbjct: 428 GIDA 431 >SMc01217 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 489 Score = 150 bits (379), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 139/441 (31%), Positives = 214/441 (48%), Gaps = 14/441 (3%) Query: 11 VALTGGVALYAINVHIVTTILPSVVRDIGGLAYYAWNVTLFVAASIVGSALTGKLMGAMG 70 V L GVAL+A N V+T LP+ V + GG A +W TL++ +IVG AL L G Sbjct: 39 VTLCLGVALFAFNEFFVSTALPTAVAEFGGAALLSWAFTLYLVFAIVGGALAASLKVRFG 98 Query: 71 ARATYLMALALFGSGALLCGSAGSMGWMLAGRAVQGIGGGLLAALAYALIPLVFEPRMWP 130 AR T ++A +F +G + A SM +LAGR +QG G G++AAL YALIP +F R+ P Sbjct: 99 ARNTLIVAALVFATGTAIATMASSMPQVLAGRVLQGFGEGIIAALCYALIPELFPQRLVP 158 Query: 131 RAIALVSGMWGVSTLLGPAVGGLFAASGHWRVAFFALLPLLAAQAWLVWRQLGPATVRSA 190 + + +W + GP + GL WR AFF +P A ++ L A +R Sbjct: 159 KIFGAEAIVWAAAAFGGPLISGLLTEYWSWRAAFFVNIPAAA-----IFIALVVAILRQP 213 Query: 191 SGPAQAVPQFLLGRIALLASSVLLVALAAQADDDWLASACVLAGVLLAVWMARIDLRHRA 250 +A L R+ ++L++L+ A D + SA + A + + V D R Sbjct: 214 KQSPRAAGSVPLLRLVAFGFGIMLISLSNTAADGYSMSALLAAALAVFVATVHFDRRSPQ 273 Query: 251 NLLPHAAYRPRTVMGGVMACIALLVMGSCV-EIFLPYFLQGLHGYDPLGAGYATAAMAAG 309 ++LP A+ +G + + L+ + ++L Y LQ L G+ P AG++ A MA Sbjct: 274 SILPFGAFSFDRPLGTGLWVVLLMPLAQASGSVYLVYALQHLWGFGPTAAGFSNALMAIS 333 Query: 310 WSLGSLGGSGLSGRAALRMIRLGPCMMTLGMALLAFLMPAQWLPAGALADGLIVLALGVT 369 WSL ++ + L R+ +RL L L A + +G GL+ ++ Sbjct: 334 WSLTAIIVASL--RSHETRVRLVWTGPLFLCLGLGGLTLA--VASGEY--GLVFVSQSAV 387 Query: 370 GLGIGMGWPHLVARALHAAQPGEENLTSSAITTVQLFAMALGAALAGLVANQAGLGAGGA 429 G G G+ W L ++ + E + TS+ + T+Q A+GAA+ G VAN G G + Sbjct: 388 GAGFGLCWGTLSQLLMNVSSIEERDKTSALLPTLQSAGYAIGAAVFGAVANAGGFDEGVS 447 Query: 430 EATARAAWVLLALFTLAPALA 450 AA +L +F L LA Sbjct: 448 ARVISAA--MLGVFALGCVLA 466