BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0006.0003.p (475 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO1712 [GEPR] COG0477 Permeases of the major facilitator superf... 452 e-127 yebQ [GEPR] COG0477 Permeases of the major facilitator superfami... 440 e-123 Z2875 [GEPR] COG0477 Permeases of the major facilitator superfam... 440 e-123 ECs2538 [GEPR] COG0477 Permeases of the major facilitator superf... 440 e-123 STM1843 [GEPR] COG0477 Permeases of the major facilitator superf... 424 e-118 >YPO1712 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 452 bits (1164), Expect = e-127, Method: Compositional matrix adjust. Identities = 232/444 (52%), Positives = 315/444 (70%), Gaps = 2/444 (0%) Query: 22 EGLPPEQRGRAILALGIAVGLATLDTAIANTALPAMALDLNTTPAASVWIVTAYQLAMMV 81 +GLP QR AIL + + + +A LD IAN ALP +A DLNT+PA S+W+V AYQLA+ + Sbjct: 7 DGLPVPQRYAAILVIALGIMMAVLDGTIANVALPTIARDLNTSPATSIWVVNAYQLAITI 66 Query: 82 ALLPLAALGEIVGYRRIYIWGLVLFTAASLLCAVAWSLPTLVMARFLQGLGGAGIMSVNT 141 +LL +A+LG+I+GYRR+Y GL++F+ SL CA++ SL TL AR LQG G A +MSVNT Sbjct: 67 SLLSMASLGDIIGYRRVYQAGLLIFSVTSLFCALSDSLWTLTFARVLQGFGAAALMSVNT 126 Query: 142 ALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVAAVIL 201 ALIR IYP LGRG+G+NTLIVA++ GPS+A+ +L++A W WLFA+NVP+G+ A L Sbjct: 127 ALIRIIYPRAQLGRGIGINTLIVAVSSAAGPSIAAAVLSVASWQWLFALNVPIGLLAWCL 186 Query: 202 ALPSLP--HTALSTHAFDLRSAVLNAAAFGLLILAIGEGAHQAEASVVGLELGAAIVCGL 259 + LP +T + + FD+ S VLNA FGLLI AI + +V+ ++ A ++ G Sbjct: 187 GIKFLPANNTKSNGNRFDITSCVLNALTFGLLITAISGFSQGQSPAVIAAQVVALLLIGF 246 Query: 260 FLLKRELSHPAPMLPVDLFRHPMFTLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQVEI 319 F ++R+L+ P+LPVDL R P+F LS T++ SFAAQ LA VSLPFF LGR +V Sbjct: 247 FFVRRQLTQSFPLLPVDLLRIPIFALSIGTSIFSFAAQMLAMVSLPFFLQTVLGRDEVAT 306 Query: 320 GLLMTPWPVAVAIMAPIAGRLSDRYPVGLLGGVGLALLCAGLLSMTFMPAAPTVWEISWR 379 GLL+TPWP+A ++APIAGRL +RY GLLGG+GLA+ +GL + +PA P+ +I WR Sbjct: 307 GLLLTPWPLATMVIAPIAGRLVERYHAGLLGGIGLAVFASGLFLLAVLPANPSDVDIIWR 366 Query: 380 MLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCFNLSETQ 439 M+LCG GFG FQ+PN ++++AP HRSGGASG++ TARLLGQ+ GAALVAL FN+ T Sbjct: 367 MILCGAGFGLFQTPNNHTIISAAPQHRSGGASGMLGTARLLGQTSGAALVALMFNMFSTN 426 Query: 440 GSRFALGFGAAFAGVACIASFLRM 463 G+ +L FA +A + S LR+ Sbjct: 427 GTHASLILAGCFASIAALVSLLRV 450 >yebQ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 494 Score = 440 bits (1132), Expect = e-123, Method: Compositional matrix adjust. Identities = 230/429 (53%), Positives = 304/429 (70%), Gaps = 2/429 (0%) Query: 19 IAGEGLPPEQRGRAILALGIAVGLATLDTAIANTALPAMALDLNTTPAASVWIVTAYQLA 78 + +GLP QR AIL + I + +A LD AIAN ALP +A DL+ TPA+S+W+V AYQ+A Sbjct: 41 VQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIA 100 Query: 79 MMVALLPLAALGEIVGYRRIYIWGLVLFTAASLLCAVAWSLPTLVMARFLQGLGGAGIMS 138 ++++LL + LG++ GYRRIY GLV+F +SL CA++ SL L +AR +QG GGA +MS Sbjct: 101 IVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFGGAALMS 160 Query: 139 VNTALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVAA 198 VNTALIR IYP R LGRG+G+N+ IVA++ GP++A+ IL+IA W WLF +NVPLG+ A Sbjct: 161 VNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIA 220 Query: 199 VILALPSLP--HTALSTHAFDLRSAVLNAAAFGLLILAIGEGAHQAEASVVGLELGAAIV 256 ++LA+ LP + S FDL SAV+NA FGLLI A+ A +++ EL +V Sbjct: 221 LLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVV 280 Query: 257 CGLFLLKRELSHPAPMLPVDLFRHPMFTLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQ 316 G+F ++R+LS P P+LPVDL R P+F+LS T+VCSF AQ LA VSLPF+ LGRS+ Sbjct: 281 VGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSE 340 Query: 317 VEIGLLMTPWPVAVAIMAPIAGRLSDRYPVGLLGGVGLALLCAGLLSMTFMPAAPTVWEI 376 VE GLL+TPWP+A +MAP+AG L +R GLLG +GL ++ AGL S+ +PA+P I Sbjct: 341 VETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINI 400 Query: 377 SWRMLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCFNLS 436 W M+LCG GFG FQSPN ++TSAP RSGGASG++ TARLLGQS GAALVAL N Sbjct: 401 IWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVALMLNQF 460 Query: 437 ETQGSRFAL 445 G+ +L Sbjct: 461 GDNGTHVSL 469 >Z2875 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 494 Score = 440 bits (1132), Expect = e-123, Method: Compositional matrix adjust. Identities = 230/429 (53%), Positives = 304/429 (70%), Gaps = 2/429 (0%) Query: 19 IAGEGLPPEQRGRAILALGIAVGLATLDTAIANTALPAMALDLNTTPAASVWIVTAYQLA 78 + +GLP QR AIL + I + +A LD AIAN ALP +A DL+ TPA+S+W+V AYQ+A Sbjct: 41 VQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIA 100 Query: 79 MMVALLPLAALGEIVGYRRIYIWGLVLFTAASLLCAVAWSLPTLVMARFLQGLGGAGIMS 138 ++++LL + LG++ GYRRIY GLV+F +SL CA++ SL L +AR +QG GGA +MS Sbjct: 101 IVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFGGAALMS 160 Query: 139 VNTALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVAA 198 VNTALIR IYP R LGRG+G+N+ IVA++ GP++A+ IL+IA W WLF +NVPLG+ A Sbjct: 161 VNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIA 220 Query: 199 VILALPSLP--HTALSTHAFDLRSAVLNAAAFGLLILAIGEGAHQAEASVVGLELGAAIV 256 ++LA+ LP + S FDL SAV+NA FGLLI A+ A +++ EL +V Sbjct: 221 LLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVV 280 Query: 257 CGLFLLKRELSHPAPMLPVDLFRHPMFTLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQ 316 G+F ++R+LS P P+LPVDL R P+F+LS T+VCSF AQ LA VSLPF+ LGRS+ Sbjct: 281 VGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSE 340 Query: 317 VEIGLLMTPWPVAVAIMAPIAGRLSDRYPVGLLGGVGLALLCAGLLSMTFMPAAPTVWEI 376 VE GLL+TPWP+A +MAP+AG L +R GLLG +GL ++ AGL S+ +PA+P I Sbjct: 341 VETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINI 400 Query: 377 SWRMLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCFNLS 436 W M+LCG GFG FQSPN ++TSAP RSGGASG++ TARLLGQS GAALVAL N Sbjct: 401 IWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVALMLNQF 460 Query: 437 ETQGSRFAL 445 G+ +L Sbjct: 461 GDNGTHVSL 469 >ECs2538 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 494 Score = 440 bits (1132), Expect = e-123, Method: Compositional matrix adjust. Identities = 230/429 (53%), Positives = 304/429 (70%), Gaps = 2/429 (0%) Query: 19 IAGEGLPPEQRGRAILALGIAVGLATLDTAIANTALPAMALDLNTTPAASVWIVTAYQLA 78 + +GLP QR AIL + I + +A LD AIAN ALP +A DL+ TPA+S+W+V AYQ+A Sbjct: 41 VQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIA 100 Query: 79 MMVALLPLAALGEIVGYRRIYIWGLVLFTAASLLCAVAWSLPTLVMARFLQGLGGAGIMS 138 ++++LL + LG++ GYRRIY GLV+F +SL CA++ SL L +AR +QG GGA +MS Sbjct: 101 IVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFGGAALMS 160 Query: 139 VNTALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVAA 198 VNTALIR IYP R LGRG+G+N+ IVA++ GP++A+ IL+IA W WLF +NVPLG+ A Sbjct: 161 VNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIA 220 Query: 199 VILALPSLP--HTALSTHAFDLRSAVLNAAAFGLLILAIGEGAHQAEASVVGLELGAAIV 256 ++LA+ LP + S FDL SAV+NA FGLLI A+ A +++ EL +V Sbjct: 221 LLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVV 280 Query: 257 CGLFLLKRELSHPAPMLPVDLFRHPMFTLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQ 316 G+F ++R+LS P P+LPVDL R P+F+LS T+VCSF AQ LA VSLPF+ LGRS+ Sbjct: 281 VGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSE 340 Query: 317 VEIGLLMTPWPVAVAIMAPIAGRLSDRYPVGLLGGVGLALLCAGLLSMTFMPAAPTVWEI 376 VE GLL+TPWP+A +MAP+AG L +R GLLG +GL ++ AGL S+ +PA+P I Sbjct: 341 VETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINI 400 Query: 377 SWRMLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCFNLS 436 W M+LCG GFG FQSPN ++TSAP RSGGASG++ TARLLGQS GAALVAL N Sbjct: 401 IWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVALMLNQF 460 Query: 437 ETQGSRFAL 445 G+ +L Sbjct: 461 GDNGTHVSL 469 >STM1843 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 457 Score = 424 bits (1091), Expect = e-118, Method: Compositional matrix adjust. Identities = 235/444 (52%), Positives = 313/444 (70%), Gaps = 2/444 (0%) Query: 22 EGLPPEQRGRAILALGIAVGLATLDTAIANTALPAMALDLNTTPAASVWIVTAYQLAMMV 81 +GLP QR AIL + I + +A LD AIAN ALP +A DL+ +PA+S+WIV AYQ+A++V Sbjct: 7 DGLPLPQRYGAILTIIIGISMAVLDGAIANVALPTIATDLHASPASSIWIVNAYQIAIVV 66 Query: 82 ALLPLAALGEIVGYRRIYIWGLVLFTAASLLCAVAWSLPTLVMARFLQGLGGAGIMSVNT 141 +LL L+ LG++ GY RIY GLV+F +SL CA++ SL L +AR QG GGA +MSVNT Sbjct: 67 SLLSLSFLGDMFGYHRIYKCGLVVFLLSSLFCALSDSLQMLTLARIAQGFGGAALMSVNT 126 Query: 142 ALIRFIYPTRSLGRGVGLNTLIVAIAFTVGPSVASGILAIAPWPWLFAVNVPLGVAAVIL 201 ALIR IYP R LGRG+G+N+ IVA++ GP++A+ IL+I+ W WLF +NVPLG+ A+IL Sbjct: 127 ALIRLIYPQRHLGRGMGINSFIVAVSSAAGPTIAAAILSISSWKWLFLINVPLGIIALIL 186 Query: 202 ALPSLP-HTALSTH-AFDLRSAVLNAAAFGLLILAIGEGAHQAEASVVGLELGAAIVCGL 259 A+ LP + A T FDL SAV+NA FGLLI A+ A +++G EL +V G Sbjct: 187 AIRFLPANIAHDTKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIGAELLVLVVVGF 246 Query: 260 FLLKRELSHPAPMLPVDLFRHPMFTLSAITAVCSFAAQGLAFVSLPFFFHHDLGRSQVEI 319 F ++R+LS P P+LP+DL R P+F+LS T++CSF AQ LA VSLPF+ LGRS+VE Sbjct: 247 FFVRRQLSLPVPLLPIDLLRIPLFSLSIGTSICSFCAQMLAMVSLPFYLQTVLGRSEVET 306 Query: 320 GLLMTPWPVAVAIMAPIAGRLSDRYPVGLLGGVGLALLCAGLLSMTFMPAAPTVWEISWR 379 GLL+TPWP+A +MAP+AG L +R GLLG +G+ ++ AGL ++ +PA+P+ I W Sbjct: 307 GLLLTPWPLATMVMAPLAGYLIERLHAGLLGALGMVIMAAGLFALVMLPASPSDLNIIWP 366 Query: 380 MLLCGMGFGFFQSPNLKALMTSAPPHRSGGASGIVATARLLGQSVGAALVALCFNLSETQ 439 M+LCG GFG FQSPN ++TSAP RSGGASG++ TARLLGQS GAALVAL N Sbjct: 367 MILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSTGAALVALMLNQFGDS 426 Query: 440 GSRFALGFGAAFAGVACIASFLRM 463 G+ +L A A +A + S LR+ Sbjct: 427 GTHLSLLAAAILAILAAVVSGLRI 450