BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0028.p (174 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4098 [IQR] COG1028 Dehydrogenases with different specificities... 172 2e-43 SMc02336 [IQR] COG1028 Dehydrogenases with different specificiti... 156 2e-38 BS_kduD [IQR] COG1028 Dehydrogenases with different specificitie... 153 2e-37 mll4054 [IQR] COG1028 Dehydrogenases with different specificitie... 147 1e-35 CAC0361 [IQR] COG1028 Dehydrogenases with different specificitie... 145 3e-35 >PA4098 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Pae Pseudomonas aeruginosa Length = 241 Score = 172 bits (437), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 87/174 (50%), Positives = 114/174 (65%) Query: 1 VRAVLAGLTQLDIVVNCAGIIKRGEELETDVFEQVIAVNLTGTMRVCAASRALLKQSGGC 60 ++ + L +LD++VN AGI + EE + FE+V+ +NL+ M +R LL Q GG Sbjct: 68 LQRLFEALPRLDVLVNNAGISRDREEYDLATFERVLRLNLSAAMLASQLARPLLAQRGGS 127 Query: 61 IVNTASMLSFFGGGLVPGYSASKGGVAQLTKSLAIAYAADGIRVNAVAPGWIATPLTQAL 120 I+N ASM S FG P YSASKG + QLT+SLA YAA+ IRVNA+APGWI TPL L Sbjct: 128 ILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAIAPGWIDTPLGAGL 187 Query: 121 QDDPVRAGPILARTPLGRWGKPEDIGNVVAFLCSPAASFMTGAIVPVDGGYLVA 174 + D I+ RTPL RWG+ ++ + AFLC P ASF+TGA++ VDGGYL A Sbjct: 188 KADVEATRRIMQRTPLARWGEAPEVASAAAFLCGPGASFVTGAVLAVDGGYLCA 241 >SMc02336 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 252 Score = 156 bits (395), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 83/166 (50%), Positives = 106/166 (63%) Query: 8 LTQLDIVVNCAGIIKRGEELETDVFEQVIAVNLTGTMRVCAASRALLKQSGGCIVNTASM 67 L +LD++VN AGI + E E + +V+ VNL MR A LLK S G I+NTASM Sbjct: 84 LRKLDVLVNGAGIARPEAEFEDATYMEVMDVNLNSQMRFAMAVLPLLKASRGVILNTASM 143 Query: 68 LSFFGGGLVPGYSASKGGVAQLTKSLAIAYAADGIRVNAVAPGWIATPLTQALQDDPVRA 127 LS+ LVP Y ASK GV LT+ LA A+ DGIRVNA++PG+ T +T+ L DPV A Sbjct: 144 LSYVSDPLVPAYGASKSGVLGLTRHLAHAFGPDGIRVNAISPGYHKTDMTKGLWTDPVPA 203 Query: 128 GPILARTPLGRWGKPEDIGNVVAFLCSPAASFMTGAIVPVDGGYLV 173 I R+ L RWG +D+ FL SPAA F+TGA +PVDGG++V Sbjct: 204 EKIAQRSALKRWGTVDDLVGTALFLASPAAKFITGADLPVDGGFVV 249 >BS_kduD [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bsu Bacillus subtilis Length = 254 Score = 153 bits (387), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 81/166 (48%), Positives = 109/166 (65%), Gaps = 3/166 (1%) Query: 10 QLDIVVNCAGIIKR--GEELETDVFEQVIAVNLTGTMRVCA-ASRALLKQSGGCIVNTAS 66 Q+DI+VN AGII R E+ + ++ V+ VNL + A R +LK+ G I+N AS Sbjct: 87 QIDILVNNAGIIHREKAEDFPEENWQHVLNVNLNSLFILTQLAGRHMLKRGHGKIINIAS 146 Query: 67 MLSFFGGGLVPGYSASKGGVAQLTKSLAIAYAADGIRVNAVAPGWIATPLTQALQDDPVR 126 +LSF GG LVP Y+ASK VA LTKS A +AA GI+VNA+APG+I+T T+ ++DD R Sbjct: 147 LLSFQGGILVPAYTASKHAVAGLTKSFANEWAASGIQVNAIAPGYISTANTKPIRDDEKR 206 Query: 127 AGPILARTPLGRWGKPEDIGNVVAFLCSPAASFMTGAIVPVDGGYL 172 IL R P GRWG+ +DIG FL S A+ ++ G I+ VDGG+L Sbjct: 207 NEDILKRIPAGRWGQADDIGGTAVFLASRASDYVNGHILAVDGGWL 252 >mll4054 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 258 Score = 147 bits (371), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 85/167 (50%), Positives = 109/167 (65%), Gaps = 6/167 (3%) Query: 11 LDIVVNCAGIIKRGEEL---ETDVFEQVIAVNLTGTMRVCA--ASRALLKQSGGCIVNTA 65 LD +VN AGII+R + + ETD ++ V+ VNL +C A RAL G IVN A Sbjct: 91 LDGLVNNAGIIRRADAVDLTETD-WDDVMDVNLKTVFLLCQSFARRALADGRRGKIVNIA 149 Query: 66 SMLSFFGGGLVPGYSASKGGVAQLTKSLAIAYAADGIRVNAVAPGWIATPLTQALQDDPV 125 S+LSF GG V Y+ASK GV +T+ LA +AA GI VNA+APG++ T TQAL+ DP Sbjct: 150 SVLSFQGGIRVASYTASKHGVLGITRLLACEWAAKGINVNAIAPGYVETNNTQALRADPD 209 Query: 126 RAGPILARTPLGRWGKPEDIGNVVAFLCSPAASFMTGAIVPVDGGYL 172 R+ IL R P GRWG+P DIG+ FL + A+ +M GA VPVDGG+L Sbjct: 210 RSAAILGRIPAGRWGEPSDIGDAAVFLLARASDYMHGAAVPVDGGWL 256 >CAC0361 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Cac Clostridium acetobutylicum Length = 260 Score = 145 bits (367), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 76/167 (45%), Positives = 106/167 (63%), Gaps = 3/167 (1%) Query: 10 QLDIVVNCAGIIKRG--EELETDVFEQVIAVNLTGTMRVCA-ASRALLKQSGGCIVNTAS 66 +LDI+VN AG I+R E + +E +I NL + A++ ++KQ G I+N AS Sbjct: 93 RLDILVNNAGTIRRAPITEYRDEDWEYIINTNLNSIYHLSQRAAKIMIKQGSGKIINIAS 152 Query: 67 MLSFFGGGLVPGYSASKGGVAQLTKSLAIAYAADGIRVNAVAPGWIATPLTQALQDDPVR 126 MLSF GG VP Y+ASK GVA LTK+ A A I++NA+APG+I T T+A+++D R Sbjct: 153 MLSFQGGKFVPPYTASKHGVAGLTKAFANELADKNIQINAIAPGYIVTKNTEAIRNDESR 212 Query: 127 AGPILARTPLGRWGKPEDIGNVVAFLCSPAASFMTGAIVPVDGGYLV 173 IL+R P G+WG P D+ V FL S A+ ++ G I+ VDGG+LV Sbjct: 213 NNEILSRIPAGKWGYPFDVMGTVVFLASRASDYINGHILAVDGGWLV 259