BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0015.p (424 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2741 [E] COG0014 Gamma-glutamyl phosphate reductase Rso Ralst... 578 e-165 PA4007 [E] COG0014 Gamma-glutamyl phosphate reductase Pae Pseudo... 534 e-151 aq_1071 [E] COG0014 Gamma-glutamyl phosphate reductase Aae Aquif... 428 e-119 CAC3254 [E] COG0014 Gamma-glutamyl phosphate reductase Cac Clost... 408 e-113 SMc03777 [E] COG0014 Gamma-glutamyl phosphate reductase Sme Sino... 402 e-112 >RSc2741 [E] COG0014 Gamma-glutamyl phosphate reductase Rso Ralstonia solanacearum Length = 426 Score = 578 bits (1490), Expect = e-165, Method: Compositional matrix adjust. Identities = 302/423 (71%), Positives = 343/423 (81%), Gaps = 4/423 (0%) Query: 3 NIDLYMNRIGQQARAASRAMPTCAYDTAAKNQALLLIAAAIRRDADVLRAANALDLDAAR 62 +++ YM +G+QARAASR M TA KN+ALL +AAAIRRDA L+ NA D++ AR Sbjct: 5 DVNEYMALVGRQARAASRGMARAG--TAQKNRALLHLAAAIRRDAARLKDVNARDVERAR 62 Query: 63 ANGLAEAMLDRLTLSDKAIATMAEGLEQIASLPDPIGEISNMKYRPTGIQVGQMRVPLGV 122 ANG A +DRLTL+D+AI TMA GLEQIA+LPDPIGEISN+K+RPTGIQVGQMRVPLGV Sbjct: 63 ANGQDAAFIDRLTLTDRAIETMAAGLEQIAALPDPIGEISNVKFRPTGIQVGQMRVPLGV 122 Query: 123 IGIIYEARPNVTVDAAGLCIKSGNATILRGGSEAIHCNQALAKLVKEGLAGAGLPEQAVQ 182 IGIIYE+RPNVTVDAA LCIKSGNATILRGGSEAI N ALA L++EGLA AGLP AVQ Sbjct: 123 IGIIYESRPNVTVDAAALCIKSGNATILRGGSEAIESNGALAALIEEGLADAGLPATAVQ 182 Query: 183 VVETTDRAAVGALITMQEYVDVIVPRGGKGLIERLMKEAKVPMIKHLDGICHVYIDDKAD 242 VV T DRAAVG LITM EYVDVIVPRGGK LI RLM+EA+VPMIKHLDGICHVYID AD Sbjct: 183 VVATPDRAAVGKLITMTEYVDVIVPRGGKSLIARLMEEARVPMIKHLDGICHVYIDVDAD 242 Query: 243 TRKALDVAFNAKCHRYGTCNTMETLLVSRNIAAAILPPLSELYRVKEVELRCDPEAAEIL 302 KA+ + NAK RY CNTMETLLV+R +AA L PL+ +Y+ K VELR P+ L Sbjct: 243 IDKAVRICDNAKTQRYAPCNTMETLLVAREVAARALTPLARIYQDKGVELRVCPDTRATL 302 Query: 303 --AGYPLLKAATEEDWDTEYLAPILAVKVVADMDEAIEHINRHSSQHTDSIITEDYTRAM 360 AG+ LK ATE DW TEYLAPIL+++ V +D AIEHIN + S HTDSI+TE+Y+ M Sbjct: 303 EAAGFSGLKDATEADWHTEYLAPILSIRTVDGVDAAIEHINTYGSAHTDSIVTENYSTGM 362 Query: 361 RFLREVDSASVMVNASTRFADGFEYGLGAEIGISNDKLHARGPVGLEGLTSLKYVVLGQG 420 RFLREVDSASVM+NASTRFADGFEYGLGAEIGISNDKLHARGPVGLEGLTSLKYVV G G Sbjct: 363 RFLREVDSASVMINASTRFADGFEYGLGAEIGISNDKLHARGPVGLEGLTSLKYVVFGHG 422 Query: 421 QVR 423 ++R Sbjct: 423 EIR 425 >PA4007 [E] COG0014 Gamma-glutamyl phosphate reductase Pae Pseudomonas aeruginosa Length = 421 Score = 534 bits (1375), Expect = e-151, Method: Compositional matrix adjust. Identities = 289/422 (68%), Positives = 334/422 (79%), Gaps = 4/422 (0%) Query: 2 ENIDLYMNRIGQQARAASRAMPTCAYDTAAKNQALLLIAAAIRRDADVLRAANALDLDAA 61 E++ YM+R+G+ ARAASR + A TA KN+ALL A A+ L AN DL A Sbjct: 3 ESVLDYMSRLGRDARAASRLLARAA--TAQKNRALLAAADALDAARAELSHANEQDLAAG 60 Query: 62 RANGLAEAMLDRLTLSDKAIATMAEGLEQIASLPDPIGEISNMKYRPTGIQVGQMRVPLG 121 RANGL AMLDRL L+ I M EGL Q+A+LPDPIGEI +M+Y P+GIQ+G+MRVPLG Sbjct: 61 RANGLEPAMLDRLALTPARIDDMIEGLRQVATLPDPIGEIRDMRYVPSGIQIGKMRVPLG 120 Query: 122 VIGIIYEARPNVTVDAAGLCIKSGNATILRGGSEAIHCNQALAKLVKEGLAGAGLPEQAV 181 V+GIIYE+RPNVT+DAA LC+KSGNATILRGGSEAIH NQA+A+ +++GLA AGLP AV Sbjct: 121 VVGIIYESRPNVTIDAASLCLKSGNATILRGGSEAIHSNQAIARCIQQGLAEAGLPAAAV 180 Query: 182 QVVETTDRAAVGALITMQEYVDVIVPRGGKGLIERLMKEAKVPMIKHLDGICHVYIDDKA 241 QVVETTDRAAVGALI+M EYVDVIVPRGGKGLIER+ +EAKVP+IKHLDGICHVYID A Sbjct: 181 QVVETTDRAAVGALISMPEYVDVIVPRGGKGLIERISREAKVPVIKHLDGICHVYIDVAA 240 Query: 242 DTRKALDVAFNAKCHRYGTCNTMETLLVSRNIAAAILPPLSELYRVKEVELRCDPEAAEI 301 D KA+ VA NAK RY CNTMETLLV IA +LPPL+ +YR K VELR D A Sbjct: 241 DLDKAIRVADNAKTQRYAPCNTMETLLVHAGIAERVLPPLATIYREKGVELRGDA-ATRA 299 Query: 302 LAGYPLLKAATEEDWDTEYLAPILAVKVVADMDEAIEHINRHSSQHTDSIITEDYTRAMR 361 L G +L+ ATEEDW TEY APIL++++V +D AIEHIN + SQHTD+IITE+++ A R Sbjct: 300 LLGADVLE-ATEEDWRTEYNAPILSIRIVDGLDAAIEHINTYGSQHTDAIITENFSDARR 358 Query: 362 FLREVDSASVMVNASTRFADGFEYGLGAEIGISNDKLHARGPVGLEGLTSLKYVVLGQGQ 421 FL EVDSASVMVNASTRFADGFEYGLGAEIGIS DKLHARGPVGLEGLTS KYVV G G Sbjct: 359 FLAEVDSASVMVNASTRFADGFEYGLGAEIGISTDKLHARGPVGLEGLTSEKYVVFGDGH 418 Query: 422 VR 423 VR Sbjct: 419 VR 420 >aq_1071 [E] COG0014 Gamma-glutamyl phosphate reductase Aae Aquifex aeolicus Length = 443 Score = 428 bits (1101), Expect = e-119, Method: Compositional matrix adjust. Identities = 211/422 (50%), Positives = 293/422 (69%), Gaps = 6/422 (1%) Query: 8 MNRIGQQA-RAASRAMPTCAYDTAAKNQALLLIAAAIRRDADVLRAANALDLDAARANGL 66 MN I ++ RA S + T+ KN+ LL +A I ++ D ++ N D++ A+ GL Sbjct: 9 MNYIEEKVNRARSVLRELTSLKTSVKNETLLKVAELIDKNRDYIKEENRKDVEKAKEMGL 68 Query: 67 AEAMLDRLTLSDKAIATMAEGLEQIASLPDPIGEISNMKYRPTGIQVGQMRVPLGVIGII 126 A++DRL L+DK I M + L+ +ASLPDP+GEI M P G++VG+MRVPLGVI I+ Sbjct: 69 RPAVVDRLVLNDKRIDGMVKVLKDVASLPDPVGEIIKMWNLPNGLKVGRMRVPLGVIFIV 128 Query: 127 YEARPNVTVDAAGLCIKSGNATILRGGSEAIHCNQALAKLVKEGLAGAGLPEQAVQVVET 186 YE+RPNVT++A+ LC+KS NA ILRGG EAI+ N+AL L+KE G PE AVQ ++ Sbjct: 129 YESRPNVTIEASSLCMKSSNAVILRGGKEAINSNKALVNLIKEACRETGFPEDAVQFIDR 188 Query: 187 TDRAAVGALITMQEYVDVIVPRGGKGLIERLMKEAKVPMIKHLDGICHVYIDDKADTRKA 246 ++R V ++ M+ +DV +PRGG+ LI +++ AKVP+IKH G+C++Y+DD+AD KA Sbjct: 189 SEREIVWEILKMEGKIDVAIPRGGESLIRAVVEHAKVPVIKHYKGVCNIYVDDEADLEKA 248 Query: 247 LDVAFNAKCHRYGTCNTMETLLVSRNIAAAILPPLSELYRVKEVELRCDPEAAEILAGYP 306 + +NAK R CN +E L+++R I P ++ VELRCD E+ +++ P Sbjct: 249 YHIVYNAKVQRPSVCNAVENLVINRKILKEFFPKMAYYLGKAGVELRCDEESLQVIKENP 308 Query: 307 LL-----KAATEEDWDTEYLAPILAVKVVADMDEAIEHINRHSSQHTDSIITEDYTRAMR 361 L K ATEED+ E+L ILAVKVV D+DEAI I ++ S+H+D+IITE+YT+AM+ Sbjct: 309 KLSFVNAKPATEEDYYEEFLDLILAVKVVDDVDEAIAFIEKYGSKHSDAIITENYTKAMK 368 Query: 362 FLREVDSASVMVNASTRFADGFEYGLGAEIGISNDKLHARGPVGLEGLTSLKYVVLGQGQ 421 FLREVDSA+V VNASTRF DG E+GLGAE+GIS DK+HARGP+ LE LT K+V+LG+GQ Sbjct: 369 FLREVDSAAVYVNASTRFTDGNEFGLGAEMGISTDKIHARGPMALEELTIPKFVILGEGQ 428 Query: 422 VR 423 VR Sbjct: 429 VR 430 >CAC3254 [E] COG0014 Gamma-glutamyl phosphate reductase Cac Clostridium acetobutylicum Length = 418 Score = 408 bits (1049), Expect = e-113, Method: Compositional matrix adjust. Identities = 201/422 (47%), Positives = 294/422 (69%), Gaps = 5/422 (1%) Query: 3 NIDLYMNRIGQQARAASRAMPTCAYDTAAKNQALLLIAAAIRRDADVLRAANALDLDAAR 62 +I Y+ I + ++ A++ + DT KN+AL+ ++ A+ + D + + N +D++ A Sbjct: 2 DIKDYVINIAKNSKLAAKKLSYA--DTNTKNKALIEMSKALLENKDYILSQNKIDIENAE 59 Query: 63 ANGLAEAMLDRLTLSDKAIATMAEGLEQIASLPDPIGEISNMKYRPTGIQVGQMRVPLGV 122 G ++A++DRLTL+DK I MAE L + +SL DPIGE+ M P +Q+GQMRVPLGV Sbjct: 60 KIGTSKALIDRLTLNDKRITDMAEALIKTSSLQDPIGEVIKMWKTPDELQIGQMRVPLGV 119 Query: 123 IGIIYEARPNVTVDAAGLCIKSGNATILRGGSEAIHCNQALAKLVKEGLAGAGLPEQAVQ 182 IGIIYEARPNVTVDAA LCIKSGN+ ILRGG EAI+ N A+AK++K + AGLP+ +++ Sbjct: 120 IGIIYEARPNVTVDAAALCIKSGNSVILRGGKEAINSNTAIAKIIKNAVVTAGLPDGSIE 179 Query: 183 VVETTDRAAVGALITMQEYVDVIVPRGGKGLIERLMKEAKVPMIKHLDGICHVYIDDKAD 242 ++ TDR V ++ + +DV++PRGG GLI+ +++ + VP+I+ G CHVY+D AD Sbjct: 180 FIDITDRETVNVMMRLNGLIDVLIPRGGAGLIKSVVENSSVPVIETGTGNCHVYVDKYAD 239 Query: 243 TRKALDVAFNAKCHRYGTCNTMETLLVSRNIAAAILPPLSELYRVKEVELRCDPEAAEIL 302 KA + NAK R CN ME+LLV +++A LP +S + +V++R +I+ Sbjct: 240 FDKAERIIINAKLQRPAVCNAMESLLVHKDVAHEFLPRISSKLKELKVQIRGCAATQKIV 299 Query: 303 AGYPLLKAATEEDWDTEYLAPILAVKVVADMDEAIEHINRHSSQHTDSIITEDYTRAMRF 362 + AT+ED+ E+L IL+VKVV ++EAI+HI ++S++H+++IITE+YT A RF Sbjct: 300 KD---IVPATDEDFGKEFLDLILSVKVVDSLEEAIDHIFKYSTKHSEAIITENYTNAQRF 356 Query: 363 LREVDSASVMVNASTRFADGFEYGLGAEIGISNDKLHARGPVGLEGLTSLKYVVLGQGQV 422 L+EVD+A+V VNASTRF DG ++G G EIGIS KLHARGP+GLE LT+ KYV+ G GQ+ Sbjct: 357 LKEVDAAAVYVNASTRFTDGEQFGFGGEIGISTQKLHARGPMGLEQLTTTKYVIYGDGQI 416 Query: 423 RQ 424 R+ Sbjct: 417 RK 418 >SMc03777 [E] COG0014 Gamma-glutamyl phosphate reductase Sme Sinorhizobium meliloti Length = 427 Score = 402 bits (1033), Expect = e-112, Method: Compositional matrix adjust. Identities = 210/424 (49%), Positives = 289/424 (68%), Gaps = 8/424 (1%) Query: 2 ENIDLYMNRIGQQARAASRAMPTCAYDTAAKNQALLLIAAAI-RRDADVLRAANALDLDA 60 ++++ M IG++A+AA+R + T + + K+ AL+ +A I R A++L AANALDL+ Sbjct: 9 KDVNAMMLEIGRRAKAAARPLATASAER--KHAALVAMAGVIVTRTAEIL-AANALDLEN 65 Query: 61 ARANGLAEAMLDRLTLSDKAIATMAEGLEQIASLPDPIGEISNMKYRPTGIQVGQMRVPL 120 AR +G+A A +DRLTL++ I MA+G+ IA L DP+GE+ + RP G+ + ++R PL Sbjct: 66 ARESGVASAFIDRLTLTESRIRDMADGIRAIAELIDPVGEVISEWDRPNGLHIERVRTPL 125 Query: 121 GVIGIIYEARPNVTVDAAGLCIKSGNATILRGGSEAIHCNQALAKLVKEGLAGAGLPEQA 180 GVIG+IYE+RPNVT DA LC+K+GNA ILRGGS++ H ++A+ + EGL AGLPE A Sbjct: 126 GVIGVIYESRPNVTADAGALCLKAGNAVILRGGSDSFHSSRAIHACLTEGLKVAGLPEDA 185 Query: 181 VQVVETTDRAAVGALIT-MQEYVDVIVPRGGKGLIERLMKEAKVPMIKHLDGICHVYIDD 239 +Q+V DRAAVGA++T + +DVIVPRGGK L+ R+ EA+VP+ HL+G+CH+Y+D Sbjct: 186 IQMVPVADRAAVGAMLTGLNGAIDVIVPRGGKSLVARVQNEARVPVFAHLEGLCHIYVDA 245 Query: 240 KADTRKALDVAFNAKCHRYGTCNTMETLLVSRNIAAAILPPLSELYRVKEVELRCDPEAA 299 AD A + NAK R G C ETLL+ RN A PL E E+R + A Sbjct: 246 SADRDMAKKIVVNAKMRRTGICGAAETLLIDRNAAEKFAKPLLEALVDAGCEVRASDDLA 305 Query: 300 EILAGYPLLKAATEEDWDTEYLAPILAVKVVADMDEAIEHINRHSSQHTDSIITEDYTRA 359 ++ P LKAAT+EDW TEYL I++ ++V + AIEHIN SS HT+++I ED Sbjct: 306 SVM---PGLKAATDEDWATEYLDAIISARLVDGISGAIEHINTWSSAHTEAVIAEDPAVV 362 Query: 360 MRFLREVDSASVMVNASTRFADGFEYGLGAEIGISNDKLHARGPVGLEGLTSLKYVVLGQ 419 RF E+DSA ++ NAST+FADG E+G+G EIGI+ K+HARGPVG+E LTS KY V G Sbjct: 363 ERFFSEIDSAILLHNASTQFADGGEFGMGGEIGIATGKMHARGPVGVEQLTSFKYRVRGT 422 Query: 420 GQVR 423 GQVR Sbjct: 423 GQVR 426