BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0147.p (427 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 342 1e-93 RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 313 6e-85 RSp0536 [GEPR] COG0477 Permeases of the major facilitator superf... 305 1e-82 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 296 4e-80 PA5476 [GEPR] COG0477 Permeases of the major facilitator superfa... 286 7e-77 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 342 bits (877), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 181/409 (44%), Positives = 270/409 (66%), Gaps = 8/409 (1%) Query: 19 RAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGAV 78 R + ++ IGNALEW+D ++YG + +IA+ FFP+GD+ SLL+ ATFGV FFMRP+G V Sbjct: 12 RQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFGVGFFMRPVGGV 71 Query: 79 VLGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYATIGLLAPAGIALGKMIQGFSAGGE 138 +LG Y+DR GRKAA+ L I+LMT+ AMIAF P+YA IG+ AP I + +M+QGF+ GGE Sbjct: 72 LLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIARMLQGFATGGE 131 Query: 139 FGSSTAFLVEHA-PHRRGFFSSWQVASQGISLLLAAIFGAVLNNMLTPEQLASWGWRVPF 197 + S+TAFLVE A PHRRG + SWQ+ Q +++ A GA++ + L E L SWGWRVPF Sbjct: 132 YASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAEALESWGWRVPF 191 Query: 198 IFGLLIAPAGIYIRRHLDEAPEF----KESSEKTDAPLRDTFAHQKMRLLIGAGSVIMAT 253 +FGLLI P G++IRR++ E F +E E+ L + +L+ G ++ T Sbjct: 192 LFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQG--LLGVLREYRRSVLVSMGLTVVGT 249 Query: 254 VSVYLSLY-IPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGAMSDKIGRTPFMITSS 312 VS Y+ L +PT+A KQLGLP F A +M + PL G +SD++GR P ++ ++ Sbjct: 250 VSFYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLVIPLAGGLSDRVGRRPVLLVAT 309 Query: 313 ALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFASMPALLADIFPVATRGTGMSL 372 ++++ YP+F ++ +P +LLL+Q ++ + +F P +A+ FPV R TG+++ Sbjct: 310 LAFMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFPVRVRSTGLAV 369 Query: 373 AYNIAVTIFGGFAGLIITWLIDFTGNKLSVSYFVIFGAVLSLIATLAAR 421 AYN+AV +FGGFA I+TWL + G+ ++ +++V+ A L L+ATL R Sbjct: 370 AYNLAVMLFGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLATLYLR 418 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 313 bits (801), Expect = 6e-85, Method: Compositional matrix adjust. Identities = 179/406 (44%), Positives = 247/406 (60%), Gaps = 9/406 (2%) Query: 19 RAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGAV 78 R+I GN LE +D ++YG +A IA FFP ++ +SL+L+ TFGV F MRPLGA+ Sbjct: 12 RSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFGVGFLMRPLGAL 71 Query: 79 VLGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYATIGLLAPAGIALGKMIQGFSAGGE 138 +LGAY DR GR+A L+L++ LM GT +IA +P YATIGL AP + +G+++QGFSAG E Sbjct: 72 ILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGRLLQGFSAGVE 131 Query: 139 FGSSTAFLVE-HAPHRRGFFSSWQVASQGISLLLAAIFGAVLNNMLTPEQLASWGWRVPF 197 G + +L E P R+GFF SWQ ASQ ++++ AA+ G +L+ L+P+++ WGWRVPF Sbjct: 132 LGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKEMGEWGWRVPF 191 Query: 198 IFGLLIAPAGIYIRRHLDEAPEFKESSEKTDAPLRDTFAH--QKMRLLIGAGS--VIMAT 253 + G LI P IRR L E EFK+ K L + F + R L+GAG+ V+M T Sbjct: 192 LVGCLIVPFLFLIRRSLQETEEFKQ--RKHRPALGEIFRSMGENWR-LVGAGTLLVVMTT 248 Query: 254 VSVYL-SLYIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGAMSDKIGRTPFMITSS 312 VS YL + Y PT+ L L S G F P++G++SD+IGR P +IT + Sbjct: 249 VSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGRRPLLITFT 308 Query: 313 ALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFASMPALLADIFPVATRGTGMSL 372 AL ++ YP +L P F +LL ++ + L Y +M L +I P A R TG SL Sbjct: 309 ALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPAVRTTGFSL 368 Query: 373 AYNIAVTIFGGFAGLIITWLIDFTGNKLSVSYFVIFGAVLSLIATL 418 AY++A IFGGF I TWLI TGNK ++ F A+ L+ATL Sbjct: 369 AYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVATL 414 >RSp0536 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 441 Score = 305 bits (781), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 172/414 (41%), Positives = 254/414 (61%), Gaps = 4/414 (0%) Query: 12 TTHPQARRAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFF 71 T+ P+ R A+ ++ +GNA EWFD +YG FA VIA FP+ + +LLL ATFGV F Sbjct: 13 TSLPRQRHAVATAILGNAFEWFDFTLYGFFAPVIATVLFPSANPFTALLLAIATFGVGFV 72 Query: 72 MRPLGAVVLGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYATIGLLAPAGIALGKMIQ 131 RPLG +VLG Y+DR GR+ AL LS +LM +GTA+IA P+YA G+ AP + +++Q Sbjct: 73 TRPLGGIVLGIYADRRGRRPALALSALLMALGTALIAIAPTYAQAGIAAPVIAVIARLLQ 132 Query: 132 GFSAGGEFGSSTAFLVEHAPH-RRGFFSSWQVASQGISLLLAAIFGAVLNNMLTPEQLAS 190 GFSAGGE G +TA+L E AP +R F++SW AS G++++ A+ G + ++L E L + Sbjct: 133 GFSAGGEMGGATAYLNEIAPPGKRAFYTSWIQASVGLAIVCGAMLGTLATSLLDAEALRA 192 Query: 191 WGWRVPFIFGLLIAPAGIYIRRHLDEAPEFKESSE--KTDAPLRDTFAHQKMRLLIGAGS 248 WGWR+PF G+LI P G IR LDE P F ++ + D+PL + + +LIGA Sbjct: 193 WGWRIPFALGVLIGPIGYVIRSRLDETPAFARAATEARADSPLLEVVRRHRRAVLIGASI 252 Query: 249 VIMATVSVYLSL-YIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGAMSDKIGRTPF 307 VI+ TV Y+ L Y+ TYA+ L LP+ + FA +G+ M + +PL G ++D++G Sbjct: 253 VILWTVCTYVLLFYMQTYAIHVLKLPSSAGFAGSMASGVTMMLTAPLFGWLADRLGYQRV 312 Query: 308 MITSSALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFASMPALLADIFPVATRG 367 + ++ +VL YP++ +L ++P L+ +Q V G+L Y +P AD+FP Sbjct: 313 LSGAALAILVLAYPLYAYLNHAPAAGTLIGVQIVFGLLSAAYTGPIPVAFADLFPTKVLS 372 Query: 368 TGMSLAYNIAVTIFGGFAGLIITWLIDFTGNKLSVSYFVIFGAVLSLIATLAAR 421 TG+S AYN+ V + GGFA +TWL L+ +V+ A++SLI TL R Sbjct: 373 TGLSTAYNLTVMLIGGFAPFYLTWLSHAFDPMLAPVLYVMVAALVSLIGTLWLR 426 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 296 bits (759), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 173/406 (42%), Positives = 243/406 (59%), Gaps = 9/406 (2%) Query: 19 RAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGAV 78 RAI GN LE FD ++YG +A IA FFP G+ +SL+L+ TFG F MRPLGA+ Sbjct: 12 RAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTFGAGFLMRPLGAI 71 Query: 79 VLGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYATIGLLAPAGIALGKMIQGFSAGGE 138 VLGAY DR GR+A L+L+++LM GT +IA +P Y TIGL AP + +G+++QGFSAGGE Sbjct: 72 VLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIGRLLQGFSAGGE 131 Query: 139 FGSSTAFLVEHA-PHRRGFFSSWQVASQGISLLLAAIFGAVLNNMLTPEQLASWGWRVPF 197 G + +L E A P R+GF+ SWQ SQ ++++ AA+ G +L+ L+P+++ WGWRVPF Sbjct: 132 PGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPKEMGEWGWRVPF 191 Query: 198 IFGLLIAPAGIYIRRHLDEAPEFKESSEKTD--APLRDTFAHQKMRLLIGAGSV--IMAT 253 + G LI P +IRR L E EF++ + LR + + L GAG++ +M T Sbjct: 192 LIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMGELLRSMGENWR---LAGAGTLLAVMTT 248 Query: 254 VSVYL-SLYIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGAMSDKIGRTPFMITSS 312 VS YL + Y PT+ L + + S G I P++G++SD+IGR +I S Sbjct: 249 VSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGRRTPLIVFS 308 Query: 313 ALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFASMPALLADIFPVATRGTGMSL 372 AL ++ YP +L P F +LL ++ + L Y +M L +I P R TG SL Sbjct: 309 ALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQLRTTGFSL 368 Query: 373 AYNIAVTIFGGFAGLIITWLIDFTGNKLSVSYFVIFGAVLSLIATL 418 AY++A IFGGF I T LI TGNK ++ F A+ L+ATL Sbjct: 369 AYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVATL 414 >PA5476 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 429 Score = 286 bits (732), Expect = 7e-77, Method: Compositional matrix adjust. Identities = 163/383 (42%), Positives = 228/383 (59%), Gaps = 3/383 (0%) Query: 20 AIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGAVV 79 AI GN LE +D ++YG +A IAK FFP + SL+L+ ATFG F MRPLGAV Sbjct: 10 AIFRVVSGNFLEMYDFMVYGFYATAIAKTFFPGDNPFASLMLSLATFGAGFLMRPLGAVF 69 Query: 80 LGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYATIGLLAPAGIALGKMIQGFSAGGEF 139 LGAY DR GR+ L++++ LM +GT +IAF+P YAT+G+ AP + G+++QGFSAG E Sbjct: 70 LGAYIDRHGRRQGLIITLGLMAMGTLLIAFVPGYATLGVAAPLLVLFGRLLQGFSAGVEL 129 Query: 140 GSSTAFLVEHA-PHRRGFFSSWQVASQGISLLLAAIFGAVLNNMLTPEQLASWGWRVPFI 198 G + +L E A P R+GFF SWQ ASQ ++++ A + G +LN L+P+ + WGWRVPF Sbjct: 130 GGVSVYLSEIATPGRKGFFVSWQSASQQVAVVFAGLLGVLLNQWLSPQDMGEWGWRVPFF 189 Query: 199 FGLLIAPAGIYIRRHLDEAPEFKESSEKTD-APLRDTFAHQKMRLLIGAGSVIMATVSVY 257 G LI PA IRR L+E PEF+ + + + + + +L G V+M TVS Y Sbjct: 190 IGCLIVPALFVIRRSLEETPEFEARTHRPSLSQVLRSIGQNFGVVLAGTAMVVMTTVSFY 249 Query: 258 L-SLYIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGAMSDKIGRTPFMITSSALYI 316 L + Y PT+ +L L S GL FI P++GA SD+IGR P ++ +SAL + Sbjct: 250 LITAYTPTFGKNELQLSDLDSLLVTMCIGLSNFIWLPVMGAFSDRIGRKPLLLGASALAL 309 Query: 317 VLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFASMPALLADIFPVATRGTGMSLAYNI 376 + YP +L P F LL ++ + L + Y +M L ++ P R TG SLAY++ Sbjct: 310 LTAYPALSWLVREPSFAGLLGVELWLSFLYSSYNGAMVVALTEVMPADVRTTGFSLAYSL 369 Query: 377 AVTIFGGFAGLIITWLIDFTGNK 399 A FGGF + TWLI N+ Sbjct: 370 ATATFGGFTPAVCTWLIHTLDNR 392