BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0120.p (658 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value FN1971 [P] COG1629 Outer membrane receptor proteins, mostly Fe t... 117 7e-26 FN0886 [P] COG1629 Outer membrane receptor proteins, mostly Fe t... 103 1e-21 fecA [P] COG4772 Outer membrane receptor for Fe3+-dicitrate Eco ... 94 9e-19 PA2289 [P] COG1629 Outer membrane receptor proteins, mostly Fe t... 83 2e-15 FN0768 [P] COG1629 Outer membrane receptor proteins, mostly Fe t... 81 8e-15 >FN1971 [P] COG1629 Outer membrane receptor proteins, mostly Fe transport Fnu Fusobacterium nucleatum Length = 657 Score = 117 bits (294), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 169/671 (25%), Positives = 274/671 (40%), Gaps = 68/671 (10%) Query: 27 LSAFAASTHAADTSQPLSAVVVSASRFPNDPAFPPVAATVITAEQIREAGIDNANEAIRK 86 + AFA + + Q VV++ F TVI A++I+E G +A+R Sbjct: 16 MCAFAEESPVLELKQ----TVVTSDSFGTPVRETAKNMTVINAKEIKEKGAKTIADALRG 71 Query: 87 LGGVYGRQSLSGPRDFPLDLRGFGTNGDQNMVVLVDGVRISENELATPLLSAIPIETIER 146 + GV RQ + G +DLRG G N V+L+DG+ +S LA L+ +P++ IE+ Sbjct: 72 VPGVVVRQ-MDGASPM-VDLRGSGATSQFNTVILLDGIPVSG--LAGFNLNTVPVDEIEK 127 Query: 147 IEIVRGGSSVLYGSGATGGTIQIITRRPQANTVRGTVIGEVGSNGQRAGRAAVSRG---W 203 IE+++G +V+YG GA GG + IIT+ P V G EVGS R R V G Sbjct: 128 IEVLQGAGAVMYGDGAIGGVVNIITKAPTKKAVYGGAGLEVGS--WRTIRENVYLGGKIG 185 Query: 204 DNMSIDASYAKSHADNWRD------NSKSNQENFSTTVQWFASDWRFGLRANLSRADFGL 257 D ++ASY+ + + ++RD N K +++ ++ + + N S Sbjct: 186 DKFLLNASYSGNSSKDYRDRSPQYENKKDKRDSLWLRGKYLLDNGSIAINYNHSEDKDYY 245 Query: 258 PGSLSQAQYDANARQTSKPLDHGSYDNDSITAFLERRFG----AFDVAAELSHREKISRS 313 GSLS+ Q+D N RQ + ND I A ++ F + ++ K ++ Sbjct: 246 TGSLSKEQFDKNPRQVGSWSGYTYGINDIINAKYNQKINDKIDIFLTSGYYHNKNKFQKN 305 Query: 314 TYVSSASTAQANIRTTQFSPRLRHVLDS--GLWKNEAIAGVDLAEWSSATNASYGNSDAS 371 ST++ IR +L + DS L + D + S D Sbjct: 306 ------STSEYFIRP---EVKLTYAKDSYVTLGLDYRDGKRDFKDDVFVNGVSQKAPDDK 356 Query: 372 QHSKALYLRDEIEFDRNARVAAGVRREQFTQQSDSGAY--------------GRTSAVNA 417 + S A Y+ ++ FD N + G RRE+ + S Y S ++ Sbjct: 357 RESFAGYVMNKTTFD-NWQFTQGYRREKVKYEYSSKVYDPMTWQLKEIKPKSADYSNNDS 415 Query: 418 WDLQASYAPLPLLRGFVKTGQSYRLATADENGFTALPSGAVLKPQVSHDLELGATLGHTA 477 ++ +Y F ++ R T + G P +K Q + E+G + Sbjct: 416 FEFGVNYLYSDTGNVFFNYARALRTPTIQDAGAWYGP----VKTQKNDIFEIGLRDAYKN 471 Query: 478 RQVTLRWFRHRVRDELYYDPTANAGFGANSNL-APTRHQGVELEGRVQLTETLGWSATYQ 536 ++ F ++E+YYD T N+ N N R G +L + L Sbjct: 472 TSISTSIFYVNSKNEIYYDKT-NSFNENNKNFDGKVRRIGAQLS-LAHYFDKLTLRERVS 529 Query: 537 HINARFEEGDNSGKQLALVP---ANTLSTRLNWKSGQQSADVGARWVDRQRMGNDFANTC 593 +I + G GK+ A V AN +T N G +A+V + +DF N Sbjct: 530 YIVPKVTSGIYDGKEFAGVSRWTANVGAT-YNITKG-LTANVDGYYQSDAYAEDDFDNYF 587 Query: 594 ARMPSFTTFDA--RYAVRVSAWEFAVTGTNLADRKY----YSQAYDCSGGAVSGIYPEDG 647 ++ ++ T DA YA + E +NL D+KY S G YP +G Sbjct: 588 SKGNNYVTVDASLSYAFE-NGIELYTGVSNLFDKKYANAVTSTRSTFGAGPRKVYYPANG 646 Query: 648 RALKFTARYDF 658 R++ +Y F Sbjct: 647 RSVYAGIKYTF 657 >FN0886 [P] COG1629 Outer membrane receptor proteins, mostly Fe transport Fnu Fusobacterium nucleatum Length = 660 Score = 103 bits (257), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 132/601 (21%), Positives = 245/601 (40%), Gaps = 104/601 (17%) Query: 25 LILSAFAASTHAADTSQPLSAVVVSASRFPNDPAFPPVAATVITAEQIREAGIDNANEAI 84 LIL+ + AD L+ V++A F T++TA+ I E G N +A+ Sbjct: 10 LILATAVYANDEADIK--LNESVITAQNFKTTVRNTASNVTIVTAKDIEEKGAQNLVDAL 67 Query: 85 RKLGGVYGRQSLSGPRDFPLDLRGFGT-NGDQNMVVLVDGVRISENELATPLLSAIPIET 143 R + G+ + + D+ G+ + + ++N ++ DGVRIS E + IPI Sbjct: 68 RMVPGIMVKNYYG---NIAFDIGGYSSVHAERNSIITYDGVRISAKEA-----TNIPISV 119 Query: 144 IERIEIVRGGSSVLYGSGATGGTIQIITR----RPQANTVRGTVIGEVGSNGQ-RAGRAA 198 IER+E++ G +LYG GA GG I I+++ + + G V E GS G + G + Sbjct: 120 IERVEVIPNGGGILYGDGANGGVINILSKSIYGKDNNKKISGNVRTEYGSRGSYKYGFST 179 Query: 199 VSRGWDNMSIDASYAKSHADNWRDN-------SKSNQENFSTTVQWFASDWRFGL-RANL 250 +++ D ++ Y++ + RD+ S+S + + ++ +D R Sbjct: 180 IAKATDKLTFKVDYSRDRYRSERDSDENGKVVSRSQEVSIDIKYKFDNADLTVKYTRNEK 239 Query: 251 SRADFGLPGSLSQAQYDAN-------ARQTSKPLD---------------------HGSY 282 RAD G L +A Y N AR ++ D + + Sbjct: 240 HRAD---GGDLEEADYYKNRKMVTWVARDFTRSNDWYVNYRQNIGENTELLTYIDLYDTR 296 Query: 283 DNDSITAFLERRFGAFDVAAELSHREKISRSTYVSSASTAQANIR----TTQFSPRLRHV 338 +ND I+ L+R + +L H+ ++ ++ + ++ +++ + Sbjct: 297 ENDDISKTLDRDYSRKTAKLQLKHK-YLNSHYFIIGTDYMKEKLKGLGYNGEYTGKNTEK 355 Query: 339 LDSGLWKNEAIAGVDLAEWSSATNASYGNSDASQHSKALYLRDEIEFDRNARVAAGVRRE 398 D G++ A+ + +++ A Y ++ Y R++ RN +R E Sbjct: 356 TDYGIF---AMNELKFGKFTFAQGLRYNKAEYD-----FYWRNKYPVPRN------IRGE 401 Query: 399 QFTQQSDSGAYGRTSAVNAWDLQASYAPLPLLRGFVKTGQSYRLATADENGFTALPSGAV 458 Q+ + A N +L+ Y+ ++ G K + +R A E +T G+ Sbjct: 402 HGEQEY------KNYAANL-ELRYDYSDTGMVYG--KWSRDFRTPIAREMYYTL--EGSK 450 Query: 459 LKPQVSHDLELGATLGHTARQVTLRWFRHRVRDELYYDPTAN-------AGFGANSNLAP 511 LK Q + E+GA ++L F + E+YY T N A N+ Sbjct: 451 LKAQTQNTFEIGAKDYIAGTYISLSTFYKKTNGEIYYQGTPNKESTRPGAVVFPYYNMGD 510 Query: 512 TRHQGVELEGRVQLTETLGWSATYQHINARFEEGD---NSGKQLALVPANTLSTRLNWKS 568 TR G+EL Q + ++ + ++N + + D K++ +VP NWK Sbjct: 511 TRRLGIELLTE-QYVKNFTFTESISYLNHKIVDSDFESRKNKEIPMVP--------NWKL 561 Query: 569 G 569 G Sbjct: 562 G 562 >fecA [P] COG4772 Outer membrane receptor for Fe3+-dicitrate Eco Escherichia coli K12 Length = 774 Score = 94.4 bits (233), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 155/668 (23%), Positives = 257/668 (38%), Gaps = 101/668 (15%) Query: 63 AATVITAEQIREAGIDNANEAIRKLGGVYGRQSL-SGPRDFPLD--LRGFGTNGDQNMVV 119 A VI E + G E + ++ GV ++ +G D ++ +RG V Sbjct: 136 ARDVIRREDFAKTGATTMREVLNRIPGVSAPENNGTGSHDLAMNFGIRGLNPRLASRSTV 195 Query: 120 LVDGVRISENELATPLLSAIPIE--TIERIEIVRGGSSVLYGSGATGGTIQIITRR-PQA 176 L+DG+ + P LS P+ ++ I++VRGG +V YG + GG + +TR PQ Sbjct: 196 LMDGIPVPFAPYGQPQLSLAPVSLGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQD 255 Query: 177 NTVRGTVIGEVG-----SNGQRAGRAAVSRGWDN-MSIDASYAKSHADNWRDNSKSNQEN 230 + V G++ +N + V DN Y+ + +WR++S + ++ Sbjct: 256 FGIEAGVEGQLSPTSSQNNPKETHNLMVGGTADNGFGTALLYSGTRGSDWREHSATRIDD 315 Query: 231 FSTTVQWFASDWRFGLRANLSRAD--FGLPGSLSQAQYDANARQTSKPLDHGSYDNDSIT 288 + +A D + L D +PG LS+A YDA+ Q+++P D Sbjct: 316 LMLKSK-YAPDEVHTFNSLLQYYDGEADMPGGLSRADYDADRWQSTRPYDR--------- 365 Query: 289 AFLERRFGA---FDVAAELSHREKIS-------RSTYVSSA---STAQANIRTTQFSPRL 335 F RR A + + H+ I RS Y+ + + N PR Sbjct: 366 -FWGRRKLASLGYQFQPDSQHKFNIQGFYTQTLRSGYLEQGKRITLSPRNYWVRGIEPRY 424 Query: 336 RHVLDSGLWKNEAIAGVDLAEWSSATNASYGNSDASQ----------------HSKALYL 379 + G +E G S+ Y + + Q + A YL Sbjct: 425 SQIFMIGPSAHEVGVGYRYLNESTHEMRYYTATSSGQLPSGSSPYDRDTRSGTEAHAWYL 484 Query: 380 RDEIEFDRNARVAAGVRREQFTQQSDSGAYGRTSAVNAWDLQASY-APLPLLRGFVKTGQ 438 D+I+ N + G+R E + +A+ + SY APLP L Sbjct: 485 DDKIDIG-NWTITPGMRFEHIESY-------QNNAITGTHEEVSYNAPLPALNVLYHLTD 536 Query: 439 SYRLATADENGF---------TALPSGAVLKPQVSHDLELGATLGHTARQVTLRWFRHRV 489 S+ L E F A+ SG V +P+ + ELG A + F Sbjct: 537 SWNLYANTEGSFGTVQYSQIGKAVQSGNV-EPEKARTWELGTRYDDGALTAEMGLFLINF 595 Query: 490 RDELYYDPTANAGFGANSNLAPTRHQGVELEGRVQ---LTETL---GWSATYQHINARF- 542 ++ YD +N + TRH G+E + R LT TL A+Y ++NA Sbjct: 596 NNQ--YD--SNQTNDTVTARGKTRHTGLETQARYDLGTLTPTLDNVSIYASYAYVNAEIR 651 Query: 543 EEGDNSGKQLALVPANTLSTRLNWKSGQQSADVGARWVDRQRMGNDFANTC--------A 594 E+GD G + P + + +++K G + ++ + + Q N ANT Sbjct: 652 EKGDTYGNLVPFSPKHKGTLGVDYKPGNWTFNLNSDFQSSQFADN--ANTVKESADGSTG 709 Query: 595 RMPSFTTFDARYAV----RVSAWEFAVTGTNLADRKYYSQAYDCSGGAVSGIYPEDGRAL 650 R+P F + AR A +++ A N+ D+ Y+ ++YD + GIY R L Sbjct: 710 RIPGFMLWGARVAYDFGPQMADLNLAFGVKNIFDQDYFIRSYDDNN---KGIYAGQPRTL 766 Query: 651 KFTARYDF 658 F Sbjct: 767 YMQGSLKF 774 >PA2289 [P] COG1629 Outer membrane receptor proteins, mostly Fe transport Pae Pseudomonas aeruginosa Length = 710 Score = 82.8 bits (203), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 158/681 (23%), Positives = 262/681 (38%), Gaps = 73/681 (10%) Query: 13 PRPRIA--LRTASVLILSAFAASTHAADTSQPLSAVVVSASRFPNDPAFPPVAATVITAE 70 PRP L S+ + A + + L +VV+ S P+D P + I Sbjct: 5 PRPSFVSHLLPGSLALCGLAIACAVQGEERRSLEPMVVTGSYNPSDTFDLPFSVDSIERR 64 Query: 71 QIREAGID-NANEAIRKLGGVYGRQSLSGPRDFPLDLRGFGTN---GDQNMVVLVDGVRI 126 QI + + N +E + ++ G+ + + +D + RG+G G + + +L DG+ Sbjct: 65 QIADGQLGINLSEVLPRVPGLVVQNRQNYAQDLQISSRGYGARSAFGIRGLKLLADGIPA 124 Query: 127 SENELATPLLSAIPIETIERIEIVRGGSSVLYGSGATGGTIQIITRRPQANTVRGTVIGE 186 S + + + ++ ERIE++RG +S +YGS A GG IQ+ +R Q R Sbjct: 125 STPD-GQGQAATLNLDVAERIEVLRGPASTIYGSNA-GGVIQMFSRDGQG-APRVGAEAT 181 Query: 187 VGSNGQRAGRAAVSRGWDNMSIDASYAKSHADNWRDNSKSNQENFSTTVQWFA-SDWRFG 245 VGS+G D + ++ D +RD+S + ++ + + +D R Sbjct: 182 VGSDGLSRNHLYTEGEGDGVGFLVDASRMDTDGYRDHSAARRDQTFAKLNFRPDADSRLA 241 Query: 246 L-RANLSRADFGLPGSLSQAQYDANARQTSKPLD----HGSYDNDSITAFLERRFG--AF 298 L ++L + D P + Y + R + + S D+ ER FG Sbjct: 242 LIYSSLEQNDIEDPLGQTWDAYKYDPRSVTANAELYDTRKSIDHQQAGMNYERYFGEATL 301 Query: 299 DVAAELSHR-----EKISRSTYVSSASTAQANIRTTQF-------SPRLRHVLDSGLWKN 346 V A + R + I + S Q N F + R + + Sbjct: 302 QVNAYVGKRSVVQYQAIPKQIGCESNPRCQRNGAVIDFDRDFHGGTVRWLQPVSQAPGEL 361 Query: 347 EAIAGVDLAEWSSATNASYGNSDASQHS-KALYLRDEIE----FDRNAR---------VA 392 G+D + S Y N + Q K RDE++ D + + Sbjct: 362 NLTVGLDYDQ-SRDDRRGYQNFNGDQLGVKGKLRRDEVDTATSLDPYLQASWAIDAWTLQ 420 Query: 393 AGVRREQFTQQSD-------SGAYGRTSAVNAWDLQASYAPLPLLRGFVKTGQSYRLATA 445 AGVR + D + R N YA P L G++ G+ + T Sbjct: 421 AGVRHSTMKMEVDDRYLSNGDASGSRRYRKNTPSFSVMYAFTPDLHGYLSAGKGFETPTQ 480 Query: 446 DENGFTALPSGAV------LKPQVSHDLELG--ATLGHTARQVTLRWFRHRVRDELYYDP 497 E + + + A LKP S E G A L R V F+ R DE+ Sbjct: 481 AEMAYAPVAANAPDVFNFGLKPATSSQYEAGLKARLWGNTR-VNAAIFQVRTEDEIVV-A 538 Query: 498 TANAGFGANSNLAPTRHQGVELEGRVQLTETLGWSATYQHINAR----FEEGDNS---GK 550 ++ G + N T +G EL +L+E + Y ++A FE G + GK Sbjct: 539 SSLGGRTSYQNAGKTLRRGFELGLESELSEHWNANLAYTRLSATYDSDFEAGGKTIGKGK 598 Query: 551 QLALVPANTLSTRLNWKSGQQSADVGARWVDRQRMGNDFANTCARMPSFTTFD--ARYAV 608 L VP ++L L WK + +G + R ++ + +N+ PS+ F+ R+ Sbjct: 599 HLPGVPESSLFGELVWKPA-EGISMGWEGMYRSQVYVEDSNSEKAAPSYAVFNWRTRFEQ 657 Query: 609 RVSAWEF--AVTGTNLADRKY 627 R+ AW F V NL DR+Y Sbjct: 658 RLGAWTFHQLVRLDNLFDRQY 678 >FN0768 [P] COG1629 Outer membrane receptor proteins, mostly Fe transport Fnu Fusobacterium nucleatum Length = 715 Score = 81.3 bits (199), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 69/230 (30%), Positives = 115/230 (50%), Gaps = 17/230 (7%) Query: 66 VITAEQIREAGIDNANEAIRKLGGVYGRQSLSGPRDFPLDLRGFGTNGDQNMV-VLVDGV 124 +IT++ I G + +E + + GV ++ L P +D+RG G + V +LVDGV Sbjct: 43 IITSKDIETKGYTSVSEILDSVPGVNVQEGLR-P---AVDVRGQGFQKAKATVQLLVDGV 98 Query: 125 ---RISENELATPLLSAIPIETIERIEIVRGGSSVLYGSGATGGTIQIITRRPQA-NTVR 180 + + + P+ + I IERIE++ GG +VLYGSG +GG I IIT++ + N VR Sbjct: 99 PANMLDTSHMNVPI-DVVNINEIERIEVIPGGGAVLYGSGTSGGVINIITKKYKGNNNVR 157 Query: 181 GTVIGEVGS--NGQRAGRAAVSRGWDNMSIDASYAKSHADNWRDNSKSNQENFSTTVQW- 237 G V ++ S N + A S G + D +Y+K+ +RD +N + FS + + Sbjct: 158 GGVGYQLASFRNNKFDVSAGTSVG--DFDFDINYSKNRKYGYRDYDFTNSDYFSGRINYN 215 Query: 238 FASDWRFGLRANLSRADFGLPGSLSQAQYDANARQTSKPLDHGSYDNDSI 287 + + R + P L Q + D N RQ+ +D + +N+ I Sbjct: 216 INKTSNIAFKYSGYRDKYTYPNFLDQKELDENRRQSG--IDKEAKENNRI 263