BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0029.p (269 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM0255 [R] COG0656 Aldo/keto reductases, related to diketogulon... 360 1e-99 yafB [R] COG0656 Aldo/keto reductases, related to diketogulonate... 360 1e-99 ZyafB [R] COG0656 Aldo/keto reductases, related to diketogulonat... 360 2e-99 ECs0203 [R] COG0656 Aldo/keto reductases, related to diketogulon... 360 2e-99 YPO1075 [R] COG0656 Aldo/keto reductases, related to diketogulon... 350 3e-96 >STM0255 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Sty Salmonella typhimurium LT2 Length = 267 Score = 360 bits (925), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 174/265 (65%), Positives = 214/265 (80%), Gaps = 1/265 (0%) Query: 6 LPALGLGTFRLKDQQVIDSIRNGLDLGYRHIDTAQIYGNEAEVGQAIAESGVARDDLFVT 65 +PA GLGTFRLKD VI S++ L+LGYR +DTAQIY NEA VGQAIAESGV R++L++T Sbjct: 3 IPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAAVGQAIAESGVPRNELYIT 62 Query: 66 TKIWTENLSRDKLLPSLKESLHKLRLDQVDLTLIHWPSPQDELPVADYLQALAEAKAQGL 125 TKIW ENLS+DKL+PSLKESL KLR D VDLTLIHWPSP D + V +++QAL EAK QGL Sbjct: 63 TKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWPSPGDAVSVEEFMQALLEAKKQGL 122 Query: 126 TRLIGISNFTIAHMEQAIAAVGAEAIATNQVEIHPFLQNRKVIDFARAKGIHLTAYMPLA 185 TR IGISNFTI ME+AIAAVGA+ IATNQ+E+ P+LQNRKV+D+A+A GIH+T+YM LA Sbjct: 123 TREIGISNFTIPLMEKAIAAVGADNIATNQIELSPYLQNRKVVDWAKAHGIHITSYMTLA 182 Query: 186 YGKVMEDATLLEIAARHGVSAAQVALAWSLQQGFAVIPSSTRRENLAANLQAQRLTLSEA 245 YGK ++D + IAA+H + AQV LAW++ +G++VIPSSTRRENLA++L AQ L L Sbjct: 183 YGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSVIPSSTRRENLASSLLAQDLHLDAE 242 Query: 246 EMQAIAALDRGERLANP-GFAPQWD 269 + AIAALD +RL +P G AP WD Sbjct: 243 DKNAIAALDCNDRLVSPEGLAPAWD 267 >yafB [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Eco Escherichia coli K12 Length = 267 Score = 360 bits (925), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 173/265 (65%), Positives = 213/265 (80%), Gaps = 1/265 (0%) Query: 6 LPALGLGTFRLKDQQVIDSIRNGLDLGYRHIDTAQIYGNEAEVGQAIAESGVARDDLFVT 65 +PA GLGTFRLKD VI S+ L+LGYR IDTAQIY NEA VGQAIAESGV R +L++T Sbjct: 3 IPAFGLGTFRLKDDVVISSVITALELGYRAIDTAQIYDNEAAVGQAIAESGVPRHELYIT 62 Query: 66 TKIWTENLSRDKLLPSLKESLHKLRLDQVDLTLIHWPSPQDELPVADYLQALAEAKAQGL 125 TKIW ENLS+DKL+PSLKESL KLR D VDLTLIHWPSP DE+ V +++QAL EAK QGL Sbjct: 63 TKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPNDEVSVEEFMQALLEAKKQGL 122 Query: 126 TRLIGISNFTIAHMEQAIAAVGAEAIATNQVEIHPFLQNRKVIDFARAKGIHLTAYMPLA 185 TR IGISNFTI ME+AIAAVGAE IATNQ+E+ P+LQNRKV+ +A+ GIH+T+YM LA Sbjct: 123 TREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQNRKVVAWAKQHGIHITSYMTLA 182 Query: 186 YGKVMEDATLLEIAARHGVSAAQVALAWSLQQGFAVIPSSTRRENLAANLQAQRLTLSEA 245 YGK ++D + IAA+H + AQV LAW++ +G++VIPSST+R+NL +NL+AQ L L Sbjct: 183 YGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSVIPSSTKRKNLESNLKAQNLQLDAE 242 Query: 246 EMQAIAALDRGERLANP-GFAPQWD 269 + +AIAALD +RL +P G AP+WD Sbjct: 243 DKKAIAALDCNDRLVSPEGLAPEWD 267 >ZyafB [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase EcZ Escherichia coli O157:H7 EDL933 Length = 267 Score = 360 bits (923), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 172/265 (64%), Positives = 213/265 (80%), Gaps = 1/265 (0%) Query: 6 LPALGLGTFRLKDQQVIDSIRNGLDLGYRHIDTAQIYGNEAEVGQAIAESGVARDDLFVT 65 +PA GLGTFRLKD VI S++ L+LGYR IDTAQIY NEA VG AIAESGV R +L++T Sbjct: 3 IPAFGLGTFRLKDDVVISSVKTALELGYRAIDTAQIYDNEAAVGLAIAESGVPRHELYIT 62 Query: 66 TKIWTENLSRDKLLPSLKESLHKLRLDQVDLTLIHWPSPQDELPVADYLQALAEAKAQGL 125 TKIW ENLS+DKL+PSLKESL KLR D VDLTLIHWPSP DE+ V +++QAL EAK +GL Sbjct: 63 TKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPNDEVSVEEFMQALLEAKKEGL 122 Query: 126 TRLIGISNFTIAHMEQAIAAVGAEAIATNQVEIHPFLQNRKVIDFARAKGIHLTAYMPLA 185 TR IGISNFTI ME+AIAAVGAE IATNQ+E+ P+LQNRKV+ +A+ GIH+T+YM LA Sbjct: 123 TREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQNRKVVAWAKQHGIHITSYMTLA 182 Query: 186 YGKVMEDATLLEIAARHGVSAAQVALAWSLQQGFAVIPSSTRRENLAANLQAQRLTLSEA 245 YGK ++D + IAA+H + AQV LAW++ +G++VIPSST+RENL +NL+AQ L L Sbjct: 183 YGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSVIPSSTKRENLESNLKAQNLQLDAE 242 Query: 246 EMQAIAALDRGERLANP-GFAPQWD 269 + +AIAALD +RL +P G AP+WD Sbjct: 243 DKKAIAALDCNDRLVSPEGLAPEWD 267 >ECs0203 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Ecs Escherichia coli O157:H7 Length = 267 Score = 360 bits (923), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 172/265 (64%), Positives = 213/265 (80%), Gaps = 1/265 (0%) Query: 6 LPALGLGTFRLKDQQVIDSIRNGLDLGYRHIDTAQIYGNEAEVGQAIAESGVARDDLFVT 65 +PA GLGTFRLKD VI S++ L+LGYR IDTAQIY NEA VG AIAESGV R +L++T Sbjct: 3 IPAFGLGTFRLKDDVVISSVKTALELGYRAIDTAQIYDNEAAVGLAIAESGVPRHELYIT 62 Query: 66 TKIWTENLSRDKLLPSLKESLHKLRLDQVDLTLIHWPSPQDELPVADYLQALAEAKAQGL 125 TKIW ENLS+DKL+PSLKESL KLR D VDLTLIHWPSP DE+ V +++QAL EAK +GL Sbjct: 63 TKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPNDEVSVEEFMQALLEAKKEGL 122 Query: 126 TRLIGISNFTIAHMEQAIAAVGAEAIATNQVEIHPFLQNRKVIDFARAKGIHLTAYMPLA 185 TR IGISNFTI ME+AIAAVGAE IATNQ+E+ P+LQNRKV+ +A+ GIH+T+YM LA Sbjct: 123 TREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQNRKVVAWAKQHGIHITSYMTLA 182 Query: 186 YGKVMEDATLLEIAARHGVSAAQVALAWSLQQGFAVIPSSTRRENLAANLQAQRLTLSEA 245 YGK ++D + IAA+H + AQV LAW++ +G++VIPSST+RENL +NL+AQ L L Sbjct: 183 YGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSVIPSSTKRENLESNLKAQNLQLDAE 242 Query: 246 EMQAIAALDRGERLANP-GFAPQWD 269 + +AIAALD +RL +P G AP+WD Sbjct: 243 DKKAIAALDCNDRLVSPEGLAPEWD 267 >YPO1075 [R] COG0656 Aldo/keto reductases, related to diketogulonate reductase Ype Yersinia pestis Length = 267 Score = 350 bits (897), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 167/265 (63%), Positives = 206/265 (77%), Gaps = 1/265 (0%) Query: 6 LPALGLGTFRLKDQQVIDSIRNGLDLGYRHIDTAQIYGNEAEVGQAIAESGVARDDLFVT 65 +P GLGTFRL+DQ VIDS+ L LGYR IDTAQIY NEA VGQAI ESG+ RD+LF+T Sbjct: 3 IPVFGLGTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQAIQESGINRDELFIT 62 Query: 66 TKIWTENLSRDKLLPSLKESLHKLRLDQVDLTLIHWPSPQDELPVADYLQALAEAKAQGL 125 TKIW NLS+DKL+PSL+ES+ KL+ D VDLTLIHWPSP DE+ VA+++ L +AK GL Sbjct: 63 TKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWPSPNDEVSVAEFMSELLKAKGLGL 122 Query: 126 TRLIGISNFTIAHMEQAIAAVGAEAIATNQVEIHPFLQNRKVIDFARAKGIHLTAYMPLA 185 TR IGISNFTI M+QAIAAVGAE IATNQ+E+ P LQNR V+DFA+ GI +T+YM LA Sbjct: 123 TRQIGISNFTIDLMKQAIAAVGAEEIATNQIELSPLLQNRNVVDFAKQNGIAVTSYMTLA 182 Query: 186 YGKVMEDATLLEIAARHGVSAAQVALAWSLQQGFAVIPSSTRRENLAANLQAQRLTLSEA 245 YGK + + + IA +HG + AQV L+W++Q G+ VIPSST+ NLA+NL AQ+L L+ A Sbjct: 183 YGKALAEPVIKTIAEQHGATPAQVILSWAMQLGYGVIPSSTKAANLASNLLAQKLCLNAA 242 Query: 246 EMQAIAALDRGERLANP-GFAPQWD 269 +M IA LDR ERL +P G AP+WD Sbjct: 243 DMALIATLDRNERLVSPDGLAPKWD 267