BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0008.p (277 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2534 [IQR] COG1028 Dehydrogenases with different specificitie... 358 9e-99 PA2554 [IQR] COG1028 Dehydrogenases with different specificities... 316 3e-86 mlr2803 [IQR] COG1028 Dehydrogenases with different specificitie... 296 2e-80 BMEII0816 [IQR] COG1028 Dehydrogenases with different specificit... 293 4e-79 SMa1452 [IQR] COG1028 Dehydrogenases with different specificitie... 284 2e-76 >RSc2534 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Rso Ralstonia solanacearum Length = 252 Score = 358 bits (918), Expect = 9e-99, Method: Compositional matrix adjust. Identities = 179/252 (71%), Positives = 204/252 (80%) Query: 26 MRIEGNVFIVTGAASGLGAATARMIAAAGGKPVLADLNEEAGSALARELGGVFVRCDVSS 85 M I VFIVTG ASGLGA T R +A AGGK V+ADLNE AG+ALA+E+GG FVRCDVSS Sbjct: 1 MEIRDQVFIVTGGASGLGAGTTRALAEAGGKVVIADLNEAAGAALAQEIGGRFVRCDVSS 60 Query: 86 EDDAQAVVRAAQAAGSLRGLVNCAGIAPAEKLVGKNGPHSMALFMKTLNINLVGSFNMAR 145 E D QA V+AA + G+L GLVNCAGIAPA + VGK GPH + F + +NINL+G+FNM R Sbjct: 61 EADGQAAVQAATSLGALAGLVNCAGIAPASRTVGKAGPHPLDQFARVININLIGTFNMIR 120 Query: 146 FAADAMARTEAQEEGERGIIIHTASVAAYDGQIGQTAYSASKGAIVAMTLPMARDLSRSG 205 AA AM GERG+II+TASVAA+DGQIGQ AY+ASKG +VAMTL +ARDLSR G Sbjct: 121 LAATAMTANAPNAGGERGVIINTASVAAFDGQIGQAAYAASKGGVVAMTLAIARDLSRDG 180 Query: 206 IRVMTIAPGIFETPMMLAMPQEVRDSLGQAVPFPPRLGRATEYAQLARTIIENVMLNGET 265 IRVMTIAPGIFETPM+L MP EV+D+LG+ VPFPPRLG+ EYAQLAR IIEN MLNGET Sbjct: 181 IRVMTIAPGIFETPMLLGMPPEVQDALGKMVPFPPRLGKPAEYAQLARAIIENPMLNGET 240 Query: 266 IRLDGAIRMQPK 277 IRLDGAIRMQPK Sbjct: 241 IRLDGAIRMQPK 252 >PA2554 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Pae Pseudomonas aeruginosa Length = 255 Score = 316 bits (810), Expect = 3e-86, Method: Compositional matrix adjust. Identities = 170/252 (67%), Positives = 201/252 (79%), Gaps = 3/252 (1%) Query: 26 MRIEGNVFIVTGAASGLGAATARMIAAAGGKPVLADLNEEAGSALARELG--GVFVRCDV 83 MRIE VF+VTG +SGLGAATA+M+ GGK VLAD+N EAG+A A ELG FVR D+ Sbjct: 1 MRIENRVFLVTGGSSGLGAATAKMLVEQGGKVVLADINAEAGAAKAAELGAQARFVRADI 60 Query: 84 SSEDDA-QAVVRAAQAAGSLRGLVNCAGIAPAEKLVGKNGPHSMALFMKTLNINLVGSFN 142 +SE D QAV A +A G L GL NCAG+APAEK++G+NG H++ F + ++INLVGSFN Sbjct: 61 ASEADGRQAVAAALEAFGGLHGLANCAGVAPAEKVLGRNGIHALESFRRVIDINLVGSFN 120 Query: 143 MARFAADAMARTEAQEEGERGIIIHTASVAAYDGQIGQTAYSASKGAIVAMTLPMARDLS 202 M R AA+AM++ + E GERG+I++TASVAA+DGQIGQ AYSASK +V MTLP+AR+L+ Sbjct: 121 MLRLAAEAMSQGQPDEGGERGVIVNTASVAAFDGQIGQAAYSASKSGVVGMTLPIARELA 180 Query: 203 RSGIRVMTIAPGIFETPMMLAMPQEVRDSLGQAVPFPPRLGRATEYAQLARTIIENVMLN 262 R GIRVMTIAPGIFETPMM MPQEVRDSLG +VPFPPRLGR EYA L R IIEN MLN Sbjct: 181 RFGIRVMTIAPGIFETPMMAGMPQEVRDSLGASVPFPPRLGRPDEYAALVRQIIENSMLN 240 Query: 263 GETIRLDGAIRM 274 GE IRLDGAIRM Sbjct: 241 GEVIRLDGAIRM 252 >mlr2803 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 253 Score = 296 bits (759), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 153/253 (60%), Positives = 183/253 (72%), Gaps = 1/253 (0%) Query: 26 MRIEGNVFIVTGAASGLGAATARMIAAAGGKPVLADLNEEAGSALARELGGVFVRCDVSS 85 M G + IVTG SGLG ATAR +AA G + + D+ E + +A ++GG+ V+CDVSS Sbjct: 1 MNPNGQIAIVTGGGSGLGEATARALAAKGARVAIFDVGIERAAKVAADIGGISVQCDVSS 60 Query: 86 EDDAQAVV-RAAQAAGSLRGLVNCAGIAPAEKLVGKNGPHSMALFMKTLNINLVGSFNMA 144 D A + A G R LVNCAGIA K +GK+GPH + + K + +NL+G+FNM Sbjct: 61 ADSGTAALAETASKLGEPRILVNCAGIAIGVKTIGKDGPHPLDQYRKVIEVNLIGTFNMI 120 Query: 145 RFAADAMARTEAQEEGERGIIIHTASVAAYDGQIGQTAYSASKGAIVAMTLPMARDLSRS 204 R AD A E + GERG+I++TASVAAYDGQIGQ AYSASKG +V MTLP+ARDL+RS Sbjct: 121 RLVADRAASLEPLQGGERGVIVNTASVAAYDGQIGQAAYSASKGGVVGMTLPVARDLARS 180 Query: 205 GIRVMTIAPGIFETPMMLAMPQEVRDSLGQAVPFPPRLGRATEYAQLARTIIENVMLNGE 264 GIRV TIAPGIF+TPMM MPQEV+DSLG AVPFP RLG +EYA LA IIEN MLNGE Sbjct: 181 GIRVCTIAPGIFKTPMMAGMPQEVQDSLGAAVPFPSRLGEPSEYAALALHIIENQMLNGE 240 Query: 265 TIRLDGAIRMQPK 277 TIRLDGAIRM PK Sbjct: 241 TIRLDGAIRMAPK 253 >BMEII0816 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bme Brucella melitensis Length = 255 Score = 293 bits (749), Expect = 4e-79, Method: Compositional matrix adjust. Identities = 157/255 (61%), Positives = 195/255 (76%), Gaps = 3/255 (1%) Query: 26 MRIEGNVFIVTGAASGLGAATARMIAAAGGKPVLADLNEEAGSALARELGGV--FVRCDV 83 M+IE VF++TGA SGLGAA ++M AG K VL D+N EAG A A+ LG F R DV Sbjct: 1 MQIENRVFLITGAGSGLGAAVSKMAVEAGAKVVLLDVNAEAGEAGAKALGASARFQRTDV 60 Query: 84 SSEDDAQAVVRAAQAAGS-LRGLVNCAGIAPAEKLVGKNGPHSMALFMKTLNINLVGSFN 142 +S+ D +A + AA A S + LVNCAG+AP EK++G+ G H + F +T++INL+G+FN Sbjct: 61 ASDTDGKAAIAAAIEAFSRIDVLVNCAGVAPGEKVLGREGAHKLETFTRTISINLIGTFN 120 Query: 143 MARFAADAMARTEAQEEGERGIIIHTASVAAYDGQIGQTAYSASKGAIVAMTLPMARDLS 202 M R AA+AMA+ E + GERG+II+TASVAA+DGQIGQ AYSASKG + AMTLP+AR+L+ Sbjct: 121 MLRLAAEAMAKNEPGQGGERGVIINTASVAAFDGQIGQAAYSASKGGVAAMTLPVARELA 180 Query: 203 RSGIRVMTIAPGIFETPMMLAMPQEVRDSLGQAVPFPPRLGRATEYAQLARTIIENVMLN 262 R GIRVMTIAPGIF+TPMM MPQEV+D+LG +VPFPPRLG EYA L R I+EN MLN Sbjct: 181 RHGIRVMTIAPGIFKTPMMAGMPQEVQDALGASVPFPPRLGEPAEYAALVRHIVENQMLN 240 Query: 263 GETIRLDGAIRMQPK 277 GE IRLDGA+RM K Sbjct: 241 GEVIRLDGALRMAAK 255 >SMa1452 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 255 Score = 284 bits (726), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 146/255 (57%), Positives = 190/255 (74%), Gaps = 3/255 (1%) Query: 26 MRIEGNVFIVTGAASGLGAATARMIAAAGGKPVLADLNEEAGSALARELGGV--FVRCDV 83 M+++ VFIVTGA+SGLGAA RM+A G + DL AG A ELG F DV Sbjct: 1 MQLKSRVFIVTGASSGLGAAVTRMLAQEGATVLGLDLKPPAGEEPAAELGAAVRFRNADV 60 Query: 84 SSEDDAQAVVRAA-QAAGSLRGLVNCAGIAPAEKLVGKNGPHSMALFMKTLNINLVGSFN 142 ++E DA A + A Q G + GLVNCAG AP EK++G++GPH++ F +T+ +NL+G+FN Sbjct: 61 TNEADATAALAFAKQEFGHVHGLVNCAGTAPGEKILGRSGPHALDSFARTVAVNLIGTFN 120 Query: 143 MARFAADAMARTEAQEEGERGIIIHTASVAAYDGQIGQTAYSASKGAIVAMTLPMARDLS 202 M R AA+ M++ E +GERG+I++TAS+AA+DGQIGQ AY+ASKG + A+TLP AR+L+ Sbjct: 121 MIRLAAEVMSQGEPDADGERGVIVNTASIAAFDGQIGQAAYAASKGGVAALTLPAARELA 180 Query: 203 RSGIRVMTIAPGIFETPMMLAMPQEVRDSLGQAVPFPPRLGRATEYAQLARTIIENVMLN 262 R GIRV+TIAPGIF+TPMM MPQ+V+D+L +VPFPPRLGRA EYA L + I EN MLN Sbjct: 181 RFGIRVVTIAPGIFDTPMMAGMPQDVQDALAASVPFPPRLGRAEEYAALVKHICENTMLN 240 Query: 263 GETIRLDGAIRMQPK 277 GE IRLDGA+RM P+ Sbjct: 241 GEVIRLDGALRMAPR 255