BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0003.0051.p (374 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mlr7407 [GEPR] COG0477 Permeases of the major facilitator superf... 267 3e-71 Rv2994 [GEPR] COG0477 Permeases of the major facilitator superfa... 106 9e-23 MT3072 [GEPR] COG0477 Permeases of the major facilitator superfa... 105 1e-22 PA0811 [GEPR] COG0477 Permeases of the major facilitator superfa... 68 4e-11 >mlr7407 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 430 Score = 267 bits (682), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 194/370 (52%), Positives = 237/370 (64%), Gaps = 7/370 (1%) Query: 2 TSLVLRSDYHLSNAQLGLALGLLSLGVALGELPWGVLTDRLGDRKVLLAGLLGTSAALCL 61 T++VLR YHLSNA+LGLALG+L LGVAL ELPWG+LTDR GDR+VLL GL T+A L Sbjct: 57 TAVVLRQGYHLSNAELGLALGVLGLGVALSELPWGLLTDRWGDRRVLLIGLGATAAWLLA 116 Query: 62 LMAMARPGQGGSAFVWL-CVGLTLAGLLGGSVNGASGRAIMAWFAEGERGLAMSIRQTAV 120 + + P + G V L L GLLGGSVNG+SGRAIM WF E ERG AMSIRQTAV Sbjct: 117 MAMLVVPTRSGVPDVMLLSASLLFTGLLGGSVNGSSGRAIMGWFRENERGFAMSIRQTAV 176 Query: 121 PLGGGIGALLLPTLAARAGFGAVYGFLMTLCMTSVALVLLWLREAHEASPSHTATAPAMP 180 PLGGG+GAL+LP+LA GF AV+ L S WL E A+ + A Sbjct: 177 PLGGGLGALVLPSLALAFGFSAVFTLLAGASALSALFAWRWLHEPPAAAHVAASAAAGPA 236 Query: 181 ALRSPLVWRLALGTGLLCAPQVALISFGGIFLHEVGQAGLLLISVLLTLVQVGAAVARIA 240 LR+ VWR+A GLLC PQVA+++F +FLH+ G + IS L VQ+GA V R+ Sbjct: 237 PLRNIEVWRIATAIGLLCFPQVAVLTFASVFLHDFVGLGTVAISASLAAVQIGAMVMRVW 296 Query: 241 SGRWTDRRGQRRPYLRACALGSALLFLLLGVSSLSGLSVS------LQWLGGVLVVAGVV 294 SGR+TDR G RR +LR+C+ S L F +L + L+G +V + L VL+VAG+ Sbjct: 297 SGRFTDRHGNRRQFLRSCSALSGLAFSVLWLMVLAGSAVPGGQSFLIAVLPFVLIVAGIS 356 Query: 295 VSAWHGVAYTELAVAAGPAQVGTALGLGNSCVFGVFFLTAQAIPLLLQWHGWPAVWIVTA 354 VSAWHGVAYTELA AG VGTAL L N+ VF FFL AIP LL WP VW+ + Sbjct: 357 VSAWHGVAYTELATLAGAGHVGTALSLANTFVFVGFFLVPVAIPGLLHLWSWPGVWLSAS 416 Query: 355 AVALLVWPLF 364 AL+ WP+F Sbjct: 417 LCALIAWPIF 426 >Rv2994 [GEPR] COG0477 Permeases of the major facilitator superfamily Mtu Mycobacterium tuberculosis H37Rv Length = 445 Score = 106 bits (264), Expect = 9e-23, Method: Compositional matrix adjust. Identities = 119/374 (31%), Positives = 174/374 (46%), Gaps = 34/374 (9%) Query: 15 AQLGLALGLLSLGVALGELPWGVLTDRLGDRKVLLAGLLGTSAALCLLMAMARPGQGGSA 74 + GL + S G+ + WG L D +G+R V+ G T+AA ++ + Sbjct: 48 SHAGLLASMPSWGLVVTMFAWGYLLDHVGERMVMAVGSALTAAAAYAAASV-------HS 100 Query: 75 FVWLCVGLTLAGLLGGSVNGASGRAIMAWFAEGERGLAMSIRQTAVPLGGGIGALLLPTL 134 +W+ V L L G+ G N A GR + WF +RGLAM IRQTA PLG GAL++P L Sbjct: 101 LLWIGVFLFLGGMAAGGCNSAGGRLVSGWFPPQQRGLAMGIRQTAQPLGIASGALVIPEL 160 Query: 135 AARAGFGAVYGFLMTLC-MTSVALVLLWLREAHEASPSHTATAPAMPALRSPLVWRLALG 193 A R G A F +C + +VA VL + ++ + A P S ++WR+ Sbjct: 161 AER-GVHAGLMFPAVVCTLAAVASVLGIVDPPRKSRTKASEQELASPYRGSSILWRIHAA 219 Query: 194 TGLLCAPQVALISFGGIFL--HE---VGQAGLLLISVLLTLVQVGAAVARIASGRWTDRR 248 + LL PQ ++F ++L H V QAG VL+T+ Q+ A+ R+A GRW+D Sbjct: 220 SALLMMPQTVTVTFMLVWLINHHGWSVAQAG-----VLVTISQLLGALGRVAVGRWSDHV 274 Query: 249 GQRRPYLRACALGSALLFLLLGVSSLSGLSVSLQWLGGVLVVAGVVVSAWHGVAYTELAV 308 G R +R A +A LL G + + + V+A V+ + A TE Sbjct: 275 GSRMRPVRLIAAAAAATLFLLAAVDNEGSRYDVLLMIAISVIA-VLDNGLEATAITEY-- 331 Query: 309 AAGPAQVGTALGLGNSCVFGVFFLTAQAIPL---LLQWHGWPAVWIVT-----AAVALLV 360 AGP G ALG+ N+ + A PL L+ +P W + AAV L+ Sbjct: 332 -AGPYWSGRALGIQNTT---QRLMAAAGPPLFGSLITTAAYPTAWALCGVFPLAAVPLVP 387 Query: 361 WPLFPPARKAPASR 374 L PP + A R Sbjct: 388 VRLLPPGLETRARR 401 >MT3072 [GEPR] COG0477 Permeases of the major facilitator superfamily MtC Mycobacterium tuberculosis CDC1551 Length = 445 Score = 105 bits (263), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 119/374 (31%), Positives = 174/374 (46%), Gaps = 34/374 (9%) Query: 15 AQLGLALGLLSLGVALGELPWGVLTDRLGDRKVLLAGLLGTSAALCLLMAMARPGQGGSA 74 + GL + S G+ + WG L D +G+R V+ G T+AA ++ + Sbjct: 48 SHAGLLASMPSWGLVVTMFAWGYLLDHVGERMVMAVGSALTAAAAYAAASV-------HS 100 Query: 75 FVWLCVGLTLAGLLGGSVNGASGRAIMAWFAEGERGLAMSIRQTAVPLGGGIGALLLPTL 134 +W+ V L L G+ G N A GR + WF +RGLAM IRQTA PLG GAL++P L Sbjct: 101 LLWIGVFLFLGGMAAGGCNSAGGRLVSGWFPPQQRGLAMGIRQTAQPLGIASGALVIPEL 160 Query: 135 AARAGFGAVYGFLMTLC-MTSVALVLLWLREAHEASPSHTATAPAMPALRSPLVWRLALG 193 A R G A F +C + +VA VL + ++ + A P S ++WR+ Sbjct: 161 AER-GVHAGLMFPAVVCTLAAVASVLGIVDPPRKSRTKASEQELASPYRGSSILWRIHAA 219 Query: 194 TGLLCAPQVALISFGGIFL--HE---VGQAGLLLISVLLTLVQVGAAVARIASGRWTDRR 248 + LL PQ ++F ++L H V QAG VL+T+ Q+ A+ R+A GRW+D Sbjct: 220 SALLMMPQTVTVTFMLVWLINHHGWSVAQAG-----VLVTISQLLGALGRVAVGRWSDHV 274 Query: 249 GQRRPYLRACALGSALLFLLLGVSSLSGLSVSLQWLGGVLVVAGVVVSAWHGVAYTELAV 308 G R +R A +A LL G + + + V+A V+ + A TE Sbjct: 275 GSRMRPVRLIAAAAAATLFLLAAVDNEGSRYDVLLMIAISVIA-VLDNGLEAAAITEY-- 331 Query: 309 AAGPAQVGTALGLGNSCVFGVFFLTAQAIPL---LLQWHGWPAVWIVT-----AAVALLV 360 AGP G ALG+ N+ + A PL L+ +P W + AAV L+ Sbjct: 332 -AGPYWSGRALGIQNTT---QRLMAAAGPPLFGSLITTAAYPTAWALCGVFPLAAVPLVP 387 Query: 361 WPLFPPARKAPASR 374 L PP + A R Sbjct: 388 VRLLPPGLETRARR 401 >PA0811 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 415 Score = 67.8 bits (164), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 81/280 (28%), Positives = 131/280 (46%), Gaps = 34/280 (12%) Query: 3 SLVLRSDYHLSNAQLGLALGLLSLGVALGELPWGVLTDRLGDRKVLLAGLLGTSAALCLL 62 ++ +++D LS+ Q+GL + L +G L G L DR +R V+ G L + ALC Sbjct: 39 AVFVQNDLQLSSLQIGLLVSAAQLVPIVGLLVAGELLDRYSERLVVGLGTLIVALALCAS 98 Query: 63 MAMARPGQGGSAFVWLCVGLTLAGLLGGSVNGASGRAIMAWFAEGERGLAMSIRQTAVPL 122 + + ++ + + L + G + +++ WFA+ + G AM IRQ +PL Sbjct: 99 L-------WATDYLTILLFLVVVGAGYSTAQPGGSKSVSRWFAKTQLGFAMGIRQAGLPL 151 Query: 123 GGGIGALLLPTLAA----RAGF--GAVYGFLMTLCMTSVALVLLWLREAHEASPSHTATA 176 GG + A LLP LA R+ F G + FL L +L+ R +A P+ A Sbjct: 152 GGALSAALLPYLAGVYGWRSAFLAGGLVAFLGALAF------MLFYRTPPDA-PAPGAN- 203 Query: 177 PAMPALRSPLVWRLALGT-----GLLCAPQVALIS-------FGGIFLHEVGQAGLLLIS 224 PA L + + RLA+ T ++C+ VALIS F ++LHE + G+ + + Sbjct: 204 PAERDLGAVVKSRLAMITDPAMKNIVCS-GVALISVQYGILVFTVLYLHETLEIGIGMAA 262 Query: 225 VLLTLVQVGAAVARIASGRWTDRRGQRRPYLRACALGSAL 264 LL + Q RI W+DR R + LG+ + Sbjct: 263 TLLFVAQGSGVAGRILLAAWSDRCRAGRYFPVMVCLGAVI 302