BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0229.p (297 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 174 2e-43 RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 171 2e-42 RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 155 1e-37 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 152 7e-37 YPO1768 [GEPR] COG0477 Permeases of the major facilitator superf... 145 8e-35 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 174 bits (441), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 105/289 (36%), Positives = 163/289 (56%), Gaps = 7/289 (2%) Query: 1 VMAIFFAGVAVAGVLGGLVSGWIMRDMAGVMGLYGWQWMFAIEGAPAVVLGVLVIFLLAD 60 V +F V ++G++G +SGWIM+ G G GWQWMF +EG P+V++G+L+I+ L D Sbjct: 153 VYGLFVISVPLSGIIGAPLSGWIMQYFNGFQGYAGWQWMFILEGIPSVLVGILIIYKLKD 212 Query: 61 GPAQATWLTPEERSFLQNRQSQEALRTHHVSAHSLTALKQALSHRPTYLFAFIYFALTCG 120 ATWLT +E+ LQ EA H+ AHS L+ A +L IYF L G Sbjct: 213 RITHATWLTDKEKDILQTNIENEA--AHY--AHS--RLRDAFLQPRVWLLTLIYFCLISG 266 Query: 121 SLTLNFWMPLMIRDFGIKDVVQVSLYTVIPNAIGAIGLILIARRSDRRNERHGHFLVCTT 180 T+ FW+P +IRD G+KD++ + T IP+A A+ +I+++R +DR ER H + Sbjct: 267 FYTIGFWLPTLIRDSGVKDILSIGFLTAIPSAAAAVTMIVVSRSADRLRERRWHLALTAV 326 Query: 181 GGALALAALTLHPSSFAVSLGLLSVAAVLIFAALPIFWSLPPGLLPSQTIAPGIAFISSV 240 GA+ + T + V++ L++ A+ + +P+FWSLP L A GIAFI+S Sbjct: 327 LGAVGIILSTYFSDNIVVAMVCLTIGAMGALSTIPLFWSLPTAFLGGSAAAAGIAFINSW 386 Query: 241 GITSGIVSPWLIGLVKTRTGNIDIALYILAGLLLLSGLTMWTMIPRKGV 289 G G V+P+++G +K T + + I++ L + G + +IP K V Sbjct: 387 GNLGGFVAPYMMGYLKDLTQSTTTGMLIISTTLFI-GAALVFLIPAKAV 434 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 171 bits (434), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 95/262 (36%), Positives = 142/262 (54%), Gaps = 8/262 (3%) Query: 2 MAIFFAGVAVAGVLGGLVSGWIMRDMAGVMGLYGWQWMFAIEGAPAVVLGVLVIFLLADG 61 MA+ + GV+GG S WIM AG GL GWQWMF EG P+++LG+ L D Sbjct: 152 MAVVLGAAPLGGVIGGPASTWIMGHFAGAGGLAGWQWMFLAEGIPSILLGIAAYGYLVDK 211 Query: 62 PAQATWLTPEERSFLQNRQSQEALRTHHVSAHSLTALKQALSHRPTYLFAFIYFALTCGS 121 PA A WLT +++ + ++ A ++ +AL+ Y+ A YF L CG Sbjct: 212 PADARWLTDAQKAVIAGDIARAA-------PGQASSFGKALTEPKLYVLAAAYFCLICGV 264 Query: 122 LTLNFWMPLMIRDFGIKDVVQVSLYTVIPNAIGAIGLILIARRSDRRNERHGHFLVCTTG 181 + FW+P +++ G+ D+ Q+ LY+ IPN + + + RRSDRR ERH H + Sbjct: 265 YAVGFWLPSILKSAGLSDLFQIGLYSAIPNLAMIVAMYALGRRSDRRGERHLHSAITAVL 324 Query: 182 GALALAALTLHPSSFAVSLGLLSVAAVLIFAALPIFWSLPPGLLPSQTIAPGIAFISSVG 241 GA L A + +SF +L +++A+ IFA+ +FW++P L A GIA I+S+G Sbjct: 325 GA-GLLAWAAYATSFPAALISITLASAAIFASYSVFWAIPQQHLKGTAAAGGIALINSIG 383 Query: 242 ITSGIVSPWLIGLVKTRTGNID 263 + G SP LIG K TG++ Sbjct: 384 LFGGFFSPTLIGWTKEATGSLQ 405 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 155 bits (392), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 94/274 (34%), Positives = 152/274 (55%), Gaps = 6/274 (2%) Query: 5 FFAGVAVAGVLGGLVSGWIMRDMAGVMGLYGWQWMFAIEGAPAVVLGVLVIFLLADGPAQ 64 F VA++GV+GG +SGW ++ GV GL GWQWMF IEG P+VV+G+ V+ L + + Sbjct: 163 FMTAVALSGVIGGPISGWALKTFGGVYGLAGWQWMFLIEGIPSVVIGLCVLAYLDNRISH 222 Query: 65 ATWLTPEERSFLQNRQSQEALRTHHVSAHSLTALKQALSHRPTYLFAFIYFALTCGSLTL 124 A WLT EE++ L + E + ++ A + +L + IYF+ G + Sbjct: 223 ARWLTDEEKALLTRNIAAEEAQKEDAPIAAIMASPR------VWLMSLIYFSFVMGLYGV 276 Query: 125 NFWMPLMIRDFGIKDVVQVSLYTVIPNAIGAIGLILIARRSDRRNERHGHFLVCTTGGAL 184 +FW+P +I+ G+ D + V L T IP + ++L+AR +DR ER H + GA+ Sbjct: 277 SFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAMVLVARSADRTRERRWHIAIPALAGAI 336 Query: 185 ALAALTLHPSSFAVSLGLLSVAAVLIFAALPIFWSLPPGLLPSQTIAPGIAFISSVGITS 244 L + ++ +++ L++ + I LP+FWSLP L A GIA I+S+G + Sbjct: 337 GLVLSAVWHTNTTLAMAALTLGTMGILTTLPLFWSLPTAFLAGTGAAAGIALINSLGNLA 396 Query: 245 GIVSPWLIGLVKTRTGNIDIALYILAGLLLLSGL 278 G +SP+ +G +K T + D +Y+LA ++L L Sbjct: 397 GFLSPYAVGWLKDTTRSTDSGMYLLAASMVLGAL 430 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 152 bits (385), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 96/275 (34%), Positives = 149/275 (54%), Gaps = 6/275 (2%) Query: 1 VMAIFFAGVAVAGVLGGLVSGWIMRDMAGVMGLYGWQWMFAIEGAPAVVLGVLVIFLLAD 60 + A+F AG AG+ G +SGWIM G GWQWMF +E PAVVLGV+++ L + Sbjct: 168 MFALFQAGSPAAGIFGNPLSGWIMDQFHDTAGWQGWQWMFVLEAIPAVVLGVVILLYLDN 227 Query: 61 GPAQATWLTPEERSFLQNRQSQEALRTHHVSAHSLTALKQALSHRPTYLFAFIYFALTCG 120 A WLT EE++ + + EA ++HSL +L + + ++ IYF G Sbjct: 228 SVKAAKWLTEEEKAIIS--RDIEADSKGKAASHSLMSL---VKNPMLWVMMLIYFCFVMG 282 Query: 121 SLTLNFWMPLMIRDFGIKDVVQVSLYTVIPNAIGAIGLILIARRSDRRNERHGHFLVCTT 180 L WMP +IR G+ V + L IP I +++ +R +D ER H +V Sbjct: 283 QHGLTLWMPTLIRASGVTSNVTIGLLGAIPFICAIIAMVIFSRSADHYRERRWHLVVPAL 342 Query: 181 GGALALAALTLHPSSFAVSLGLLSVAAVLIFAALPIFWSLPPGLLPSQTIAPGIAFISSV 240 GA+ + ++ VS+ LS+AA + A P+FWSLP +L A GIA I+SV Sbjct: 343 LGAVGF-VVAASATNTTVSIIFLSMAAAGVLACAPLFWSLPTAILSGAAAAAGIALINSV 401 Query: 241 GITSGIVSPWLIGLVKTRTGNIDIALYILAGLLLL 275 +G +SP+++G+++ T + ++ +Y+LAG L+L Sbjct: 402 ANLAGFISPYMVGIIRDATHSSELGMYVLAGFLIL 436 >YPO1768 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 145 bits (367), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 104/298 (34%), Positives = 153/298 (51%), Gaps = 19/298 (6%) Query: 3 AIFFAGVAVAGVLGGLVSGWIMRDMAGVMGLYGWQWMFAIEGAPAVVLGVLVIFLLADGP 62 A+F + V LG LVSG+I+ + G + + GWQW+F +EG P+V+LG +V F L D P Sbjct: 162 ALFMVAMPVTMALGSLVSGYILA-LDGFLNMRGWQWLFLLEGFPSVLLGGVVWFYLDDTP 220 Query: 63 AQATWLTPEERSFLQNRQSQEALRTHHVSAHSLTALKQALSHRPTY-----LFAFIYFAL 117 +A WLT E++ LQ + E+ R AL Q+ R + ++ YF L Sbjct: 221 QKARWLTKEDKQCLQ--EMLESDRLQLAKQADYGALPQSAMWREIFTPVVLMYTLAYFCL 278 Query: 118 TCGSLTLNFWMPLMIRDFGIKDV-VQVSLYTVIPNAIGAIGLILIARRSDRRNERHGH-- 174 T +N W P +++ F + + L IP G+I +RRSDR ER H Sbjct: 279 TNTLSAVNIWTPQILQSFNQSSSNITIGLLAAIPQVCTIAGMIWWSRRSDRVQERKMHTV 338 Query: 175 --FLVCTTGGALALAALTLHPSSFAVSLGLLSVAAVLIFAALPIFWSLPPGLLPSQTIAP 232 +L G LA A +S LG++ +A+ F A+ IFW+ P + + A Sbjct: 339 LPYLFAAAGWVLASAT----QNSVIQLLGII-MASTGSFTAMAIFWTTPDQSISLRARAV 393 Query: 233 GIAFISSVGITSGIVSPWLIGLVKTRTGNIDIALYILAGLLLLSGLTMWTMIPRKGVP 290 GIA I++ G VSP LIG +K +TGN + LY +AGLL++ G ++ MIP K P Sbjct: 394 GIAVINATGNIGSAVSPVLIGWLKDQTGNFNSGLYFVAGLLVI-GAVIFLMIPMKKAP 450