BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0063.p (301 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1280 [G] COG0524 Sugar kinases, ribokinase family Rso Ralston... 311 9e-85 DR0728 [G] COG0524 Sugar kinases, ribokinase family Dra Deinococ... 232 8e-61 ECs3242 [G] COG0524 Sugar kinases, ribokinase family Ecs Escheri... 104 3e-22 alr0517 [G] COG0524 Sugar kinases, ribokinase family Nos Nostoc ... 103 4e-22 TM0296 [G] COG0524 Sugar kinases, ribokinase family Tma Thermoto... 99 2e-20 >RSp1280 [G] COG0524 Sugar kinases, ribokinase family Rso Ralstonia solanacearum Length = 307 Score = 311 bits (798), Expect = 9e-85, Method: Compositional matrix adjust. Identities = 163/297 (54%), Positives = 208/297 (70%), Gaps = 2/297 (0%) Query: 7 FVVFGEALTDFIRQPDGQWRAIPGGACWNVARAAARLGVATGYAGSVSTDVFGAELYALT 66 VVFGEALTDFIR+ DG+WR++ GG+CWNVAR ARLG TG+AG+VS DVFG EL AL+ Sbjct: 10 LVVFGEALTDFIREADGRWRSVAGGSCWNVARVCARLGAPTGFAGTVSRDVFGDELTALS 69 Query: 67 EAAGLDMRFTQQHAKAPLLAMVTSTTPPDYFFIGDDSADLHFDPQRLPAGWMDEARVLHF 126 AGLDMRF +Q A+ PLLAMV + PP YFFIG++SADL FD LP GW++ A+++HF Sbjct: 70 RQAGLDMRFMRQVARPPLLAMVPAAHPPQYFFIGENSADLAFDTGVLPDGWIEAAQIVHF 129 Query: 127 GCISLTREPLASRLLQIAQEAALRNKKIAFDPNWRKLMDSPSYRILLQQLLSLSHYVKVS 186 G +SL R+PLA+ LL+ A K+IAFDPN+R M P YR L+++ L+ Y+KVS Sbjct: 130 GSLSLARQPLAAHLLETATAVHAAGKRIAFDPNYRDAMAGPDYRPTLRRMAGLASYIKVS 189 Query: 187 DEDLERLFP--GDGNALATLQALAPQAEILYTLGAKGMQWIKGEQVIEQPAYRVEVVDTV 244 DEDL LFP + +ALA L+A AP A IL T GA GM I E + QPA V DTV Sbjct: 190 DEDLRGLFPELDETSALAQLRAWAPTAAILMTRGAAGMTLITPEGTLFQPALPTLVADTV 249 Query: 245 GCGDASMGGWIASQLRQPDAPAQVHLQCAAAGAAIAASKAGAYAATWDEVQAMIAAA 301 G GDASMGGW+AS L +P+A HL+ +AA AA ++ GAYA T +E+ + +A + Sbjct: 250 GAGDASMGGWLASLLTRPEAMPASHLEFSAASAAAVCARQGAYAPTREEIVSALAVS 306 >DR0728 [G] COG0524 Sugar kinases, ribokinase family Dra Deinococcus radiodurans Length = 303 Score = 232 bits (592), Expect = 8e-61, Method: Compositional matrix adjust. Identities = 132/299 (44%), Positives = 169/299 (56%), Gaps = 2/299 (0%) Query: 1 MTQSAAFVVFGEALTDFIRQPDGQWRAIPGGACWNVARAAARLGVATGYAGSVSTDVFGA 60 MT V GEALTD + W A PGGA WNVARA ARLGV + +AG+V D FG Sbjct: 1 MTSLPLIVSAGEALTDLVTAGGNTWHAHPGGAGWNVARACARLGVPSAFAGAVGQDNFGD 60 Query: 61 ELYALTEAAGLDMRFTQQHAKAPLLAMVTSTTPPDYFFIGDDSADLHFDPQRLPAGWMDE 120 +L+ + AGLD RF Q+ L+A+V ST PP Y F+G++SADLHFDP RLP GW+ Sbjct: 61 DLHRESLEAGLDPRFLQRVPAPTLMAVVYSTRPPQYRFLGENSADLHFDPTRLPGGWLGA 120 Query: 121 ARVLHFGCISLTREPLASRLLQIAQEAALRNKKIAFDPNWRKLMDSPSYRILLQQLLSLS 180 AR LH G ISL R PLA LL + + A +I+FDPN R P Y + + + Sbjct: 121 ARWLHVGGISLARWPLADTLLGVIEAARAAGVRISFDPNARIAHRHPDYPAVFAAVTKRA 180 Query: 181 HYVKVSDEDLERLFPG--DGNALATLQALAPQAEILYTLGAKGMQWIKGEQVIEQPAYRV 238 +K SDEDL FPG + AL L+ L P+ I+ T GA G ++ P V Sbjct: 181 DLLKFSDEDLAFFFPGASEAQALQELRGLNPRCPIVVTRGAAGASLYHSAGRVDLPTVPV 240 Query: 239 EVVDTVGCGDASMGGWIASQLRQPDAPAQVHLQCAAAGAAIAASKAGAYAATWDEVQAM 297 EV DTVG GD+ G + S +PDA HL+ A++ + AGAYA T +EV A+ Sbjct: 241 EVADTVGAGDSLCAGLLVSATERPDALWTEHLRFGLGAASVTCAHAGAYAPTREEVAAL 299 >ECs3242 [G] COG0524 Sugar kinases, ribokinase family Ecs Escherichia coli O157:H7 Length = 304 Score = 104 bits (259), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 91/298 (30%), Positives = 137/298 (45%), Gaps = 15/298 (5%) Query: 4 SAAFVVFGEALTDFIRQPDGQWRAIPGGACWNVARAAARLGVATGYAGSVSTDVFGAELY 63 SA V G+A+ D + + DG+ PGGA NVA ARLG +G+ G V D FGA + Sbjct: 2 SAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGTSGFIGRVGDDPFGALMQ 61 Query: 64 ALTEAAGLDMRFTQQ---HAKAPLLAMVTSTTPPDYFFIGDDSADLHFDPQRLPAGWMDE 120 G+D+ + +Q H + +L + + F+ SADL + LP W Sbjct: 62 RTLLTEGVDITYLKQDEWHRTSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPC-WR-H 119 Query: 121 ARVLHFGCISLTREPLASRLLQIAQEAALRNKKIAFDPNWRKLM--DSPSYRILLQQLLS 178 LH I+L+ EP + E ++FDPN R+ + D R+ L+Q L Sbjct: 120 GEWLHLCSIALSAEPSRTSAFTAMTEIRHAGGFVSFDPNIREDLWQDEHLLRLCLRQALQ 179 Query: 179 LSHYVKVSDEDLERLFPGDGNALATLQALAPQAEI---LYTLGAKGMQWIKGEQVIEQPA 235 L+ VK+S+E+ RL G + ALA + EI L T GA+G+ QV Sbjct: 180 LADVVKLSEEEW-RLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAG 238 Query: 236 YRVEVVDTVGCGDASMGGWI----ASQLRQPDAPAQVHLQCAAAGAAIAASKAGAYAA 289 V+ VD+ G GDA + G + ++ L + + + A A+A + GA A Sbjct: 239 MSVDCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTA 296 >alr0517 [G] COG0524 Sugar kinases, ribokinase family Nos Nostoc sp. PCC 7120 Length = 325 Score = 103 bits (257), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 95/297 (31%), Positives = 138/297 (46%), Gaps = 26/297 (8%) Query: 25 WRAIPGGACWNVARAAARLGVATGYAGSVSTDVFGAELYALTEAAGLDMRFTQQHAKAPL 84 W A PGGA NVA A +LG G+ G+V D G L L + G+D Q+H+ AP Sbjct: 31 WTAYPGGAPANVACALVKLGTPAGFIGAVGEDEPGNVLVKLLQEVGVDTTGVQRHSTAPT 90 Query: 85 LAM-VTSTTPPDYFFIG------DDSADLHFDPQRLPAGWMDEARVLHFGCISLT---RE 134 + V D F G + AD H ++LP EA L G + L E Sbjct: 91 RQVYVVRDLAGDRTFAGFGQYDTSEFADTHLQAKQLPESVFQEADFLILGTLELAYPDSE 150 Query: 135 PLASRLLQIAQEAALRNKKIAFDPNWRKLM--DSPSYRILLQQLLSLSHYVKVSDEDLER 192 R L++A++ L KI D NWR + D R +Q++ ++K++ E+ E Sbjct: 151 KAIHRALELAEQYDL---KIVLDVNWRPVFWHDENIARQKIQEIFKRVDFLKLAKEEAEW 207 Query: 193 LFPGDGNALATLQALAPQAEILYTLGAKGMQWIKGEQVIEQPAYRVEVVDTVGCGDASMG 252 LF T + L +L T G G + GE + PA+ V VVDT G GD+ + Sbjct: 208 LFDTSDPGAITYR-LGSIEGVLVTDGENGCGYCLGENEGKIPAFAVSVVDTTGAGDSFLA 266 Query: 253 GWIASQLRQ------PDAP-AQVHLQCAAAGAAIAASKAGAYAA--TWDEVQAMIAA 300 G+I QL + DA A+ + A+A A+ +KAGA A+ T EV+ +A+ Sbjct: 267 GFI-HQLSEHGIHNLNDAETAKRIITYASAVGALTTTKAGAIASQPTAMEVETFLAS 322 >TM0296 [G] COG0524 Sugar kinases, ribokinase family Tma Thermotoga maritima Length = 315 Score = 98.6 bits (244), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 85/310 (27%), Positives = 136/310 (43%), Gaps = 26/310 (8%) Query: 11 GEALTDFIRQPDGQ-------WRAIPGGACWNVARAAARLGVATGYAGSVSTDVFGAELY 63 GE L DFI + G+ +R GG+ NVA A RLG + G + D F L Sbjct: 7 GEILIDFISEDKGKNLSQSELFRKKAGGSPLNVAVALKRLGREVSFLGKLGGDQFSEFLL 66 Query: 64 ALTEAAGLDM-RFTQQHAKAPLLAMVTSTT--PPDYFFIGDDSADLHFDPQRL---PAGW 117 + + G+D + LA V PD+ F + AD + P+ + PA + Sbjct: 67 EVMKKEGIDTTHIIFDSSCKTTLAFVARDAQGNPDFVFFREKPADTNLRPEEVNIDPAQF 126 Query: 118 MDEARVLHFGCISLTREPLASRLLQIAQEAALRNKKIAFDPNWRK--LMDSPSYRILLQQ 175 LH G SL EP S L++ + K +++DPN R + D ++ + Sbjct: 127 ----SFLHIGSYSLAVEPSRSAYLKVMETFLEEGKPVSYDPNVRPSLIEDRNTFVKDFLE 182 Query: 176 LLSLSHYVKVSDEDLERLFPGDGNALATLQALAPQAEILYTLGAKG-MQWIKGEQVIEQP 234 + S VK+SD+DLE +F D + + T+G +G + KGE+ + P Sbjct: 183 ISSKVDIVKLSDKDLEYIFQEDLETAVDKIPIKENGLLFVTMGERGCLVKFKGEKRM-VP 241 Query: 235 AYRVEVVDTVGCGDASMGGWIASQLRQPDAPAQVHLQC---AAAGAAIAASKAGAYAA-- 289 +++V+ VD GCGD+ I L + + ++ A A AAI ++ G A Sbjct: 242 SFKVKPVDATGCGDSFTAAVIHKYLEKTPETIEDAVEIGKFANAVAAIVITRVGGVDAMP 301 Query: 290 TWDEVQAMIA 299 DEV+ ++ Sbjct: 302 VLDEVEMFLS 311