BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0058.p (399 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1993 [GEPR] COG0477 Permeases of the major facilitator superfa... 408 e-113 yhhS [GEPR] COG0477 Permeases of the major facilitator superfami... 329 7e-90 STM3581 [GEPR] COG0477 Permeases of the major facilitator superf... 327 3e-89 ZyhhS [GEPR] COG0477 Permeases of the major facilitator superfam... 325 2e-88 ECs4322 [GEPR] COG0477 Permeases of the major facilitator superf... 325 2e-88 >PA1993 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 402 Score = 408 bits (1048), Expect = e-113, Method: Compositional matrix adjust. Identities = 223/395 (56%), Positives = 286/395 (72%), Gaps = 6/395 (1%) Query: 7 RPLTPAK------VTRQIIATAFFTFLVYLAIGIPMAVLPGYIHLDLGYSSVIAGLGISV 60 RP PA+ VT QI++ FTF+ YL IGIP+AVLPGY+H DLGY SV+AGL IS+ Sbjct: 6 RPTPPAQDSARQNVTLQIVSVVMFTFIGYLTIGIPLAVLPGYVHDDLGYGSVLAGLVISL 65 Query: 61 QYFATFVSRANAGRMIDTMGAKHTVMRGMLLCSASGGLLLLSALAQPLPFLSLVLLFASR 120 QY AT ++R AGR+ID +G K V+ GM +ASG +LLS Q P LSL L R Sbjct: 66 QYLATLLARPYAGRVIDGLGPKRAVLYGMAGSAASGLFMLLSVAIQGWPALSLASLLVGR 125 Query: 121 AFLGLGESLVGTGAIMWGVGRVGSENTAKMISWNGIATYAALAIGAPLGVVLDRSLGFAM 180 LG ESLVG+ AI WG+GRVG+ +TAK+ISWNGIA+Y A+A+GAPLGV+L + LG Sbjct: 126 LVLGAAESLVGSAAIGWGIGRVGAPHTAKVISWNGIASYGAIALGAPLGVLLVQWLGLWS 185 Query: 181 IGLTGMLLTVLGFVLARGGPVTPVVQGEQLSFKLVLRKVFAYGMGLAFGTIGFGSIATFI 240 +G + +LL LGF LA P+V GE+L F VL +V +GMGLA G IGFG+IATFI Sbjct: 186 MGASIVLLGALGFALAWPKLPAPLVHGERLPFHHVLGRVTPHGMGLALGAIGFGTIATFI 245 Query: 241 TLYYADQHWSGAAFALTAFSSAFVGARLLFANVITRFGGYRVAVVCFLTESVGLLLLWSA 300 TLYYA + W+ A L+AF F+GARLLFAN I R GG+RVA++C ES+GLLLLWSA Sbjct: 246 TLYYASRGWANAVLCLSAFGGCFIGARLLFANSINRLGGFRVAIICLGVESLGLLLLWSA 305 Query: 301 TTPALALLGAALAGFGFALVFPSLGVEAVSLVSPANRGAALAAYSVFLDLALGITGPLAG 360 P + L GAAL GFGF+LVFP+ GVEAV+LV +NRGAAL AYS+F+DL+LGITGPL G Sbjct: 306 PNPWVGLAGAALTGFGFSLVFPAFGVEAVNLVPASNRGAALGAYSLFVDLSLGITGPLVG 365 Query: 361 AIAGQLGYPQVFLFAAIAAIGGVALSLSLYRSAQQ 395 +A G+ +FLFA +A++GG+AL+++L+R +++ Sbjct: 366 FVANLFGFRSMFLFACLASLGGLALAVALHRRSRR 400 >yhhS [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 419 Score = 329 bits (843), Expect = 7e-90, Method: Compositional matrix adjust. Identities = 188/375 (50%), Positives = 247/375 (65%), Gaps = 1/375 (0%) Query: 2 PAAAPRPLTPAKVTRQIIATAFFTFLVYLAIGIPMAVLPGYIHLDLGYSSVIAGLGISVQ 61 P A P L ++ +I++ F F YL IG+P+AVLPGY+H +G+S+ AGL IS+Q Sbjct: 18 PVAEPA-LNGLRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDVMGFSAFWAGLVISLQ 76 Query: 62 YFATFVSRANAGRMIDTMGAKHTVMRGMLLCSASGGLLLLSALAQPLPFLSLVLLFASRA 121 YFAT +SR +AGR D++G K V+ G+ C SG L + L LP +SL+LL R Sbjct: 77 YFATLLSRPHAGRYADSLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRV 136 Query: 122 FLGLGESLVGTGAIMWGVGRVGSENTAKMISWNGIATYAALAIGAPLGVVLDRSLGFAMI 181 LG+G+S GTG+ +WGVG VGS + ++ISWNGI TY A+A+GAPLGVV G + Sbjct: 137 ILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTYGAMAMGAPLGVVFYHWGGLQAL 196 Query: 182 GLTGMLLTVLGFVLARGGPVTPVVQGEQLSFKLVLRKVFAYGMGLAFGTIGFGSIATFIT 241 L M + ++ +LA P +G+ L F+ VL +V+ YGM LA + GFG IATFIT Sbjct: 197 ALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFIT 256 Query: 242 LYYADQHWSGAAFALTAFSSAFVGARLLFANVITRFGGYRVAVVCFLTESVGLLLLWSAT 301 L+Y + W GAAFALT FS AFVG RLLF N I R GG VA++CF E +GLLL+ AT Sbjct: 257 LFYDAKGWDGAAFALTLFSCAFVGTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGVAT 316 Query: 302 TPALALLGAALAGFGFALVFPSLGVEAVSLVSPANRGAALAAYSVFLDLALGITGPLAGA 361 P +A +G LAG GF+LVFP+LGV AV V N+GAALA Y+VF+DL+LG+TGPLAG Sbjct: 317 MPWMAKIGVLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGVTGPLAGL 376 Query: 362 IAGQLGYPQVFLFAA 376 + G P ++L AA Sbjct: 377 VMSWAGVPVIYLAAA 391 >STM3581 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 419 Score = 327 bits (837), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 196/403 (48%), Positives = 259/403 (64%), Gaps = 15/403 (3%) Query: 2 PAAAPRPLTPAKVTRQIIATAFFTFLVYLAIGIPMAVLPGYIHLDLGYSSVIAGLGISVQ 61 P A P L ++ +I++ F F YL IG+P+AVLPGY+H +G+S+ AGL IS+Q Sbjct: 18 PVAEPA-LNGLRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDAMGFSAFWAGLIISLQ 76 Query: 62 YFATFVSRANAGRMIDTMGAKHTVMRGMLLCSASGGLLLLSALAQPLPFLSLVLLFASRA 121 YFAT +SR +AGR D +G K V+ G+ C SG LL+ +A P +SL+LL R Sbjct: 77 YFATLLSRPHAGRYADVLGPKKIVVFGLCGCFLSGLGYLLADIASAWPMISLLLLGLGRV 136 Query: 122 FLGLGESLVGTGAIMWGVGRVGSENTAKMISWNGIATYAALAIGAPLGVVLDRSLGFAMI 181 LG+G+S GTG+ +WGVG VGS + ++ISWNGI TY A+A+GAPLGV L +A Sbjct: 137 ILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTYGAMAMGAPLGV-----LCYAWG 191 Query: 182 GLTGMLLTVLGFVLARGG-----PVTPVVQGEQLSFKLVLRKVFAYGMGLAFGTIGFGSI 236 GL G+ LTV+G L P +G+ L F+ VL +V+ YGM LA + GFG I Sbjct: 192 GLQGLALTVMGVALLAVLLALPRPSVKANKGKPLPFRAVLGRVWLYGMALALASAGFGVI 251 Query: 237 ATFITLYYADQHWSGAAFALTAFSSAFVGARLLFANVITRFGGYRVAVVCFLTESVGLLL 296 ATFITL+Y + W GAAFALT FS AFVG RLLF N I R GG VA++CF E +GLLL Sbjct: 252 ATFITLFYDAKGWDGAAFALTLFSVAFVGTRLLFPNGINRLGGLNVAMICFGVEIIGLLL 311 Query: 297 LWSATTPALALLGAALAGFGFALVFPSLGVEAVSLVSPANRGAALAAYSVFLDLALGITG 356 + +A P +A +G L G GF+LVFP+LGV AV V P N+GAALA Y+VF+D++LG+TG Sbjct: 312 VGTAAMPWMAKIGVLLTGMGFSLVFPALGVVAVKAVPPQNQGAALATYTVFMDMSLGVTG 371 Query: 357 PLAGAIAGQLGYPQVFLFAAIAAIGGVALSLSLYRSAQQGAKS 399 PLAG + G P ++L AA G VA++L L ++ S Sbjct: 372 PLAGLVMTWAGVPVIYL----AAAGLVAMALLLTWRLKKRPPS 410 >ZyhhS [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 419 Score = 325 bits (832), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 187/375 (49%), Positives = 245/375 (65%), Gaps = 1/375 (0%) Query: 2 PAAAPRPLTPAKVTRQIIATAFFTFLVYLAIGIPMAVLPGYIHLDLGYSSVIAGLGISVQ 61 P A P L ++ +I++ F F YL IG+P+AVLPGY+H +G+S+ AGL IS+Q Sbjct: 18 PVAEPA-LNGLRLNLRILSIVMFNFASYLTIGLPLAVLPGYVHDVMGFSAFWAGLVISLQ 76 Query: 62 YFATFVSRANAGRMIDTMGAKHTVMRGMLLCSASGGLLLLSALAQPLPFLSLVLLFASRA 121 YFAT +SR +AGR D +G K V+ G+ C SG L + L LP +SL+LL R Sbjct: 77 YFATLLSRPHAGRYADLLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRV 136 Query: 122 FLGLGESLVGTGAIMWGVGRVGSENTAKMISWNGIATYAALAIGAPLGVVLDRSLGFAMI 181 LG+G+S GTG+ +WGVG VGS + ++ISWN I TY A+A+GAPLGVV G + Sbjct: 137 ILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNDIVTYGAMAMGAPLGVVFYHWGGLQAL 196 Query: 182 GLTGMLLTVLGFVLARGGPVTPVVQGEQLSFKLVLRKVFAYGMGLAFGTIGFGSIATFIT 241 L M + ++ +LA P +G+ L F+ VL +V+ YGM LA + GFG IATFIT Sbjct: 197 ALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFIT 256 Query: 242 LYYADQHWSGAAFALTAFSSAFVGARLLFANVITRFGGYRVAVVCFLTESVGLLLLWSAT 301 L+Y + W GAAFALT FS AFVG RLLF N I R GG VA++CF E +GLLL+ AT Sbjct: 257 LFYDVKGWDGAAFALTLFSCAFVGTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGVAT 316 Query: 302 TPALALLGAALAGFGFALVFPSLGVEAVSLVSPANRGAALAAYSVFLDLALGITGPLAGA 361 P +A +G LAG GF+LVFP+LGV AV V N+GAALA Y+VF+DL+LG+TGPLAG Sbjct: 317 MPWMAKIGVLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGVTGPLAGL 376 Query: 362 IAGQLGYPQVFLFAA 376 + G P ++L AA Sbjct: 377 VMSWAGVPVIYLAAA 391 >ECs4322 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 419 Score = 325 bits (832), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 187/375 (49%), Positives = 245/375 (65%), Gaps = 1/375 (0%) Query: 2 PAAAPRPLTPAKVTRQIIATAFFTFLVYLAIGIPMAVLPGYIHLDLGYSSVIAGLGISVQ 61 P A P L ++ +I++ F F YL IG+P+AVLPGY+H +G+S+ AGL IS+Q Sbjct: 18 PVAEPA-LNGLRLNLRILSIVMFNFASYLTIGLPLAVLPGYVHDVMGFSAFWAGLVISLQ 76 Query: 62 YFATFVSRANAGRMIDTMGAKHTVMRGMLLCSASGGLLLLSALAQPLPFLSLVLLFASRA 121 YFAT +SR +AGR D +G K V+ G+ C SG L + L LP +SL+LL R Sbjct: 77 YFATLLSRPHAGRYADLLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRV 136 Query: 122 FLGLGESLVGTGAIMWGVGRVGSENTAKMISWNGIATYAALAIGAPLGVVLDRSLGFAMI 181 LG+G+S GTG+ +WGVG VGS + ++ISWN I TY A+A+GAPLGVV G + Sbjct: 137 ILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNDIVTYGAMAMGAPLGVVFYHWGGLQAL 196 Query: 182 GLTGMLLTVLGFVLARGGPVTPVVQGEQLSFKLVLRKVFAYGMGLAFGTIGFGSIATFIT 241 L M + ++ +LA P +G+ L F+ VL +V+ YGM LA + GFG IATFIT Sbjct: 197 ALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFIT 256 Query: 242 LYYADQHWSGAAFALTAFSSAFVGARLLFANVITRFGGYRVAVVCFLTESVGLLLLWSAT 301 L+Y + W GAAFALT FS AFVG RLLF N I R GG VA++CF E +GLLL+ AT Sbjct: 257 LFYDVKGWDGAAFALTLFSCAFVGTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGVAT 316 Query: 302 TPALALLGAALAGFGFALVFPSLGVEAVSLVSPANRGAALAAYSVFLDLALGITGPLAGA 361 P +A +G LAG GF+LVFP+LGV AV V N+GAALA Y+VF+DL+LG+TGPLAG Sbjct: 317 MPWMAKIGVLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGVTGPLAGL 376 Query: 362 IAGQLGYPQVFLFAA 376 + G P ++L AA Sbjct: 377 VMSWAGVPVIYLAAA 391