BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0054.p (344 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0381 [H] COG2022 Uncharacterized enzyme of thiazole biosynthes... 333 3e-91 XF0783 [H] COG2022 Uncharacterized enzyme of thiazole biosynthes... 310 3e-84 CC1880 Non COG 273 5e-73 aq_2178 [H] COG2022 Uncharacterized enzyme of thiazole biosynthe... 254 2e-67 BS_yjbT [H] COG2022 Uncharacterized enzyme of thiazole biosynthe... 220 3e-57 >PA0381 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis Pae Pseudomonas aeruginosa Length = 265 Score = 333 bits (854), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 163/220 (74%), Positives = 187/220 (85%) Query: 10 SEDKGLTIAGKTYRSRLLVGSGKYKDLDETRAATVASGAEIITVAIRRVNIGQDPNAPSL 69 S D IAG+TY SRLLVG+GKYKDLDETR A ASGAEI+TVA+RR NIGQ+P+ P+L Sbjct: 6 STDTPFVIAGRTYGSRLLVGTGKYKDLDETRRAIEASGAEIVTVAVRRTNIGQNPDEPNL 65 Query: 70 LDAVPPSEFTILPNTAGCYNAADAVYTLQLARELLGGHKLVKLEVLGDEKTLFPNMPETL 129 LD +PP +TILPNTAGCY+A +AV T +LARELL GH LVKLEVL D+KTLFPN+ ETL Sbjct: 66 LDVIPPDRYTILPNTAGCYDAVEAVRTCRLARELLDGHNLVKLEVLADQKTLFPNVVETL 125 Query: 130 KAAETLVKDGFDVMVYCSDDPIQARMLEDLGVAAVMPLASLIGSGMGILNPWNLSLIIEQ 189 KAAE LVKDGFDVMVY SDDPI AR L ++G AVMPLA LIGSG+GI NP+NL +I+E+ Sbjct: 126 KAAEQLVKDGFDVMVYTSDDPIIARQLAEIGCIAVMPLAGLIGSGLGICNPYNLRIILEE 185 Query: 190 ARVPVLVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDP 229 A+VPVLVDAGVGTASDAAIAMELGC+ VLMNTAIA A+DP Sbjct: 186 AKVPVLVDAGVGTASDAAIAMELGCEAVLMNTAIAHAKDP 225 >XF0783 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis Xfa Xylella fastidiosa 9a5c Length = 275 Score = 310 bits (794), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 159/247 (64%), Positives = 191/247 (77%), Gaps = 5/247 (2%) Query: 15 LTIAGKTYRSRLLVGSGKYKDLDETRAATVASGAEIITVAIRRVNIGQDPNAPSLLDAVP 74 L IAG Y SRLL G+GK+KDLDETR AT A+G++I+TVAIRRVNIGQDP+ P+LL+ + Sbjct: 21 LVIAGIVYSSRLLTGTGKFKDLDETRLATEAAGSQIVTVAIRRVNIGQDPHQPNLLNVLS 80 Query: 75 PSEFTILPNTAGCYNAADAVYTLQLARELLGGHKLVKLEVLGDEKTLFPNMPETLKAAET 134 P +TILPNTAGCY A DAV T +LARELL GH+L KLEVLGD+KTL+P++ +TLKAAE Sbjct: 81 PDRYTILPNTAGCYTAEDAVRTCRLARELLDGHRLTKLEVLGDKKTLYPDVVQTLKAAEQ 140 Query: 135 LVKDGFDVMVYCSDDPIQARMLEDLGVAAVMPLASLIGSGMGILNPWNLSLIIEQARVPV 194 LV + F VMVY SDDPI A+ LE++G AVMPLA+ IGSG+G+ N +NL IIE A+VP+ Sbjct: 141 LVAEDFQVMVYTSDDPILAKRLEEIGCVAVMPLAAPIGSGLGVQNRYNLLEIIENAQVPI 200 Query: 195 LVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDPKXRWRNRSWRWKRAAKPSSRDALRA 254 +VDAGVGTASDAAIAMELGCD VLMNTAIAGARDP R A + R+A A Sbjct: 201 IVDAGVGTASDAAIAMELGCDAVLMNTAIAGARDPVLM-----ASAMRKAVEAGREAFLA 255 Query: 255 SLPPRRR 261 PR+R Sbjct: 256 GRIPRKR 262 >CC1880 Non COG Length = 269 Score = 273 bits (697), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 145/225 (64%), Positives = 174/225 (77%), Gaps = 2/225 (0%) Query: 5 DAPLLSEDKGLTIAGKTYRSRLLVGSGKYKDLDETRAATVASGAEIITVAIRRVNIGQDP 64 D+ D+ T+AG+T+RSRL+VG+GKYKD AA A+GAEI+TVA+RRVN+ DP Sbjct: 8 DSVTADSDETWTVAGRTFRSRLIVGTGKYKDYATNAAAARAAGAEIVTVAVRRVNL-TDP 66 Query: 65 NAPSLLDAVPPSEFTILPNTAGCYNAADAVYTLQLARELLGGHKLVKLEVLGDEKTLFPN 124 + P L+D V P+EFT LPNTAGC+ DAV TL+LARE GG LVKLEVL D KTLFP+ Sbjct: 67 SQPLLVDYVKPTEFTYLPNTAGCFTGEDAVRTLRLAREA-GGWDLVKLEVLSDPKTLFPD 125 Query: 125 MPETLKAAETLVKDGFDVMVYCSDDPIQARMLEDLGVAAVMPLASLIGSGMGILNPWNLS 184 M ETL++ + LV DGF VMVYCSDDP+ AR LE+ G A+MPL + IGSG+GI N NL Sbjct: 126 MEETLRSLKLLVADGFQVMVYCSDDPVYARKLEEAGAVAIMPLGAPIGSGLGIQNRVNLR 185 Query: 185 LIIEQARVPVLVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDP 229 +IIE A+VPVLVDAGVGTASDAAI MELGCD +LMNTAIA A+DP Sbjct: 186 IIIENAKVPVLVDAGVGTASDAAIGMELGCDAILMNTAIAEAKDP 230 >aq_2178 [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis Aae Aquifex aeolicus Length = 267 Score = 254 bits (649), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 129/227 (56%), Positives = 166/227 (73%), Gaps = 2/227 (0%) Query: 3 MNDAPLLSEDKGLTIAGKTYRSRLLVGSGKYKDLDETRAATVASGAEIITVAIRRVNIGQ 62 M D L +D L IAG+ ++SRL++GSGK+KD +T+ ASGAEIITVA+RRVNI Sbjct: 1 MQDWEKLLQDDYLEIAGRKFKSRLIIGSGKFKDFQQTKEVLEASGAEIITVAVRRVNI-T 59 Query: 63 DPNAPSLLDAVPPSEFTILPNTAGCYNAADAVYTLQLARELLGGHKLVKLEVLGDEKTLF 122 DP +LLD + P ++ ILPNTAGCY A +A+ T +ARE G + VKLEV+GD+KTL Sbjct: 60 DPTKENLLDYIDPKKYLILPNTAGCYTAEEAIKTAMMAREATGIN-WVKLEVIGDQKTLL 118 Query: 123 PNMPETLKAAETLVKDGFDVMVYCSDDPIQARMLEDLGVAAVMPLASLIGSGMGILNPWN 182 P+M ET KAA+ LVK+GF V+ Y DDP+ A+ ED+G AAVMPLA+ IGSG+G+ NP+N Sbjct: 119 PDMEETYKAAKVLVKEGFVVLPYIFDDPVFAKKFEDIGCAAVMPLAAPIGSGLGLQNPYN 178 Query: 183 LSLIIEQARVPVLVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDP 229 L I E VPV+VDAG+G+A+D MELG DGVL NTA+A A+DP Sbjct: 179 LIFIKEAVSVPVIVDAGIGSATDIPPVMELGVDGVLTNTALAEAKDP 225 >BS_yjbT [H] COG2022 Uncharacterized enzyme of thiazole biosynthesis Bsu Bacillus subtilis Length = 256 Score = 220 bits (561), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 116/220 (52%), Positives = 160/220 (72%), Gaps = 2/220 (0%) Query: 15 LTIAGKTYRSRLLVGSGKYKDLDETRAATVASGAEIITVAIRRVNIGQDPNAPSLLDAVP 74 LTI GK+++SRLL+G+GKY D + A S ++I+T A+RR+NI + + P+ L+ + Sbjct: 4 LTIGGKSFQSRLLLGTGKYPSFDIQKEAVAVSESDILTFAVRRMNIFE-ASQPNFLEQLD 62 Query: 75 PSEFTILPNTAGCYNAADAVYTLQLARELLGGHKLVKLEVLGDEKTLFPNMPETLKAAET 134 S++T+LPNTAG A +AV +LA+ G ++K+EV+G ++L P+ ETLKA+E Sbjct: 63 LSKYTLLPNTAGASTAEEAVRIARLAKAS-GLCDMIKVEVIGCSRSLLPDPVETLKASEQ 121 Query: 135 LVKDGFDVMVYCSDDPIQARMLEDLGVAAVMPLASLIGSGMGILNPWNLSLIIEQARVPV 194 L+++GF V+ Y SDD + AR LE+LGV A+MP AS IGSG GILNP NLS IIEQA+VPV Sbjct: 122 LLEEGFIVLPYTSDDVVLARKLEELGVHAIMPGASPIGSGQGILNPLNLSFIIEQAKVPV 181 Query: 195 LVDAGVGTASDAAIAMELGCDGVLMNTAIAGARDPKXRWR 234 +VDAG+G+ DAA AMELG DGVL+NTA++GA DP R Sbjct: 182 IVDAGIGSPKDAAYAMELGADGVLLNTAVSGADDPVKMAR 221