BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0002.0041.p         (267 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSp0892 [Q] COG3971 2-keto-4-pentenoate hydratase Rso Ralstonia ...    69   1e-11
ZmhpD [Q] COG3971 2-keto-4-pentenoate hydratase EcZ Escherichia ...    67   4e-11
ECs0405 [Q] COG3971 2-keto-4-pentenoate hydratase Ecs Escherichi...    65   2e-10
mhpD [Q] COG3971 2-keto-4-pentenoate hydratase Eco Escherichia c...    64   3e-10

>RSp0892 [Q] COG3971 2-keto-4-pentenoate hydratase Rso Ralstonia
           solanacearum
          Length = 263

 Score = 68.9 bits (167), Expect = 1e-11,   Method: Compositional matrix adjust.
 Identities = 66/243 (27%), Positives = 106/243 (43%), Gaps = 27/243 (11%)

Query: 8   SRIIPRISESEPLSVEDAYEIAHNIRNIRVAQGEQPIGRKIGFVVRKNWERYGIIDEARI 67
           +R I +  E+E L+V DAY I       R+A+GE+  G K+GF  R    + G+ D    
Sbjct: 19  ARAIAQFGEAEQLTVPDAYAIQAASIARRLARGERRTGVKMGFTSRAKMVQMGVHDV--- 75

Query: 68  PTWAPMYDATVRFAEDNYGAQSLTGAVQPRIEPEIVFKLGKTPAPGASLLELADCLEWMA 127
             W  + DA    A +   A  L+  V PR+EPE+ F L K   P ASL E    +  +A
Sbjct: 76  -IWGRLTDA---MALEEGVAVPLSRYVHPRVEPELAFLLAKPLPPRASLAEALASVAAVA 131

Query: 128 HGFEIVVCPFPNWEFTVADSIAAFGLHGTLIVG---EPHVLSSATKHHLPQILASASVSL 184
              E++   + +++F++ D IA        ++G   +P            +  ++  + L
Sbjct: 132 PALEVIDSRYEHFKFSLTDVIADNASSSGYVIGPWADPR-----------RDFSNLGLVL 180

Query: 185 SCNTESSSVLRAAGFCNDEMDSPLHALWHLHQLLQKQTRFRQLQAGEIISTGTWTDACPI 244
           S + +   +   AG     +  PL +L  +            LQAG I+  G  T A  +
Sbjct: 181 SIDGQPRQIGSTAGI----LGHPLRSL--VAAARLAADAGEPLQAGWIVMAGGATAAEAL 234

Query: 245 EPG 247
            PG
Sbjct: 235 APG 237


>ZmhpD [Q] COG3971 2-keto-4-pentenoate hydratase EcZ Escherichia coli
           O157:H7 EDL933
          Length = 269

 Score = 67.0 bits (162), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 63/243 (25%), Positives = 105/243 (43%), Gaps = 30/243 (12%)

Query: 21  SVEDAYEIAHNIRNIRVAQGEQPIGRKIGFVVRKNWERYGIIDEARIPTWAPMYDATVRF 80
           + E AY I H      VAQG + +GRK+G    K  ++ G+ D+    T          F
Sbjct: 34  NAEAAYAIQHINVQYDVAQGRRVVGRKVGLTHPKVQQQLGV-DQPDFGTL---------F 83

Query: 81  AEDNYGAQSL---TGAVQPRIEPEIVFKLGKT-PAPGASLLELADCLEWMAHGFEIVVCP 136
           A+  YG   +   +  +QPRIE EI   L +  PA   +  EL + +EW+    E+V   
Sbjct: 84  ADMCYGDNEIIPFSRVLQPRIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSR 143

Query: 137 FPNWEFTVADSIAAFGLHGTLIVGEPHVLSSATKHHLPQILASASVSLSCNTESSSVLRA 196
             +W     D++A     G  ++G P    +         L + ++ ++ N E  S    
Sbjct: 144 IRDWSIQFVDTVADNASCGVYVIGGPAQRPAGLD------LKNCAMKMTRNNEEVS---- 193

Query: 197 AGFCNDEMDSPLH-ALWHLHQLLQKQTRFRQ-LQAGEIISTGTWTDACPIEPGQTWTTAF 254
           +G  ++ +  PL+ A+W    L +K     + L+AG+II TG       +  G  +    
Sbjct: 194 SGRGSECLGHPLNAAVW----LARKMASLGEPLRAGDIILTGALGPMVAVNAGDRFEAHI 249

Query: 255 SGV 257
            G+
Sbjct: 250 EGI 252


>ECs0405 [Q] COG3971 2-keto-4-pentenoate hydratase Ecs Escherichia coli
           O157:H7
          Length = 269

 Score = 64.7 bits (156), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 62/243 (25%), Positives = 104/243 (42%), Gaps = 30/243 (12%)

Query: 21  SVEDAYEIAHNIRNIRVAQGEQPIGRKIGFVVRKNWERYGIIDEARIPTWAPMYDATVRF 80
           + E AY I H      VAQG + +GRK+G    K  ++ G +D+    T          F
Sbjct: 34  NAEAAYAIQHINVQYDVAQGRRVVGRKVGLTHPKVQQQLG-VDQPDFGTL---------F 83

Query: 81  AEDNYGAQSL---TGAVQPRIEPEIVFKLGKT-PAPGASLLELADCLEWMAHGFEIVVCP 136
           A+  YG   +   +  +QPRIE EI   L +  PA   +  EL + +EW+    E+V   
Sbjct: 84  ADMCYGDNEIIPFSRVLQPRIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSR 143

Query: 137 FPNWEFTVADSIAAFGLHGTLIVGEPHVLSSATKHHLPQILASASVSLSCNTESSSVLRA 196
             +W     D++A     G  ++  P    +         L + ++ ++ N E  S    
Sbjct: 144 IRDWSIQFVDTVADNASCGVYVIAGPAQRPAGLD------LKNCAMKMTRNNEEVS---- 193

Query: 197 AGFCNDEMDSPLH-ALWHLHQLLQKQTRFRQ-LQAGEIISTGTWTDACPIEPGQTWTTAF 254
           +G  ++ +  PL+ A+W    L +K     + L+AG+II TG       +  G  +    
Sbjct: 194 SGRGSECLGHPLNAAVW----LARKMASLGEPLRAGDIILTGALGPMVAVNAGDRFEAHI 249

Query: 255 SGV 257
            G+
Sbjct: 250 EGI 252


>mhpD [Q] COG3971 2-keto-4-pentenoate hydratase Eco Escherichia coli K12
          Length = 271

 Score = 64.3 bits (155), Expect = 3e-10,   Method: Compositional matrix adjust.
 Identities = 62/243 (25%), Positives = 104/243 (42%), Gaps = 30/243 (12%)

Query: 21  SVEDAYEIAHNIRNIRVAQGEQPIGRKIGFVVRKNWERYGIIDEARIPTWAPMYDATVRF 80
           + E AY I H      VAQG + +GRK+G    K  ++ G+ D+    T          F
Sbjct: 36  NAEAAYAIQHINVQHDVAQGRRVVGRKVGLTHPKVQQQLGV-DQPDFGTL---------F 85

Query: 81  AEDNYGAQSL---TGAVQPRIEPEIVFKLGKT-PAPGASLLELADCLEWMAHGFEIVVCP 136
           A+  YG   +   +  +QPRIE EI   L +  PA   +  EL + +EW+    E+V   
Sbjct: 86  ADMCYGDNEIIPFSRVLQPRIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSR 145

Query: 137 FPNWEFTVADSIAAFGLHGTLIVGEPHVLSSATKHHLPQILASASVSLSCNTESSSVLRA 196
             +W     D++A     G  ++G P    +         L + ++ ++ N E  S    
Sbjct: 146 IRDWSIQFVDTVADNASCGVYVIGGPAQRPAGLD------LKNCAMKMTRNNEEVS---- 195

Query: 197 AGFCNDEMDSPLH-ALWHLHQLLQKQTRFRQ-LQAGEIISTGTWTDACPIEPGQTWTTAF 254
           +G  ++ +  PL+ A+W    L +K     + L+ G+II TG       +  G  +    
Sbjct: 196 SGRGSECLGHPLNAAVW----LARKMASLGEPLRTGDIILTGALGPMVAVNAGDRFEAHI 251

Query: 255 SGV 257
            G+
Sbjct: 252 EGI 254