BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0040.p (351 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0500 [L] COG2255 Holliday junction resolvasome, helicase subu... 596 e-170 NMA1412 [L] COG2255 Holliday junction resolvasome, helicase subu... 513 e-145 NMB1243 [L] COG2255 Holliday junction resolvasome, helicase subu... 512 e-145 VC1845 [L] COG2255 Holliday junction resolvasome, helicase subun... 481 e-136 STM1894 [L] COG2255 Holliday junction resolvasome, helicase subu... 479 e-135 >RSc0500 [L] COG2255 Holliday junction resolvasome, helicase subunit Rso Ralstonia solanacearum Length = 357 Score = 596 bits (1536), Expect = e-170, Method: Compositional matrix adjust. Identities = 299/352 (84%), Positives = 321/352 (91%), Gaps = 5/352 (1%) Query: 3 IQTDDF-----SEQRIISATPASANEEAVERALRPKQLDEYVGQEKVRSQLEIFISAARK 57 I+TD S +R+ISA+PAS NEEA ERALRPK LDEYVGQEKVR QL+IF++AA+K Sbjct: 2 IETDKLAAKAVSAERLISASPASPNEEAFERALRPKLLDEYVGQEKVRGQLDIFMTAAKK 61 Query: 58 RGEPLDHTLLFGPPGLGKTTMAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVL 117 R E LDH LLFGPPGLGKTT+AHIIAREMGVNLRQTSGPVLER GDLAALLTNLEANDVL Sbjct: 62 RREALDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERPGDLAALLTNLEANDVL 121 Query: 118 FIDEIHRMSPVVEEILYPALEDYQIDIMIGEGPAARSVRLDLQPFTLVGATTRAGMLTNP 177 FIDEIHR+SPVVEEILYPALEDYQIDIMIGEGPAARSV+LDLQPFTLVGATTRAGMLTNP Sbjct: 122 FIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTNP 181 Query: 178 LRDRFGIVARLEFYTPPELARIVTRSAGLLNAPIVEEGALEIARRSRGTPRIANRLLRRV 237 LRDRFGIVARLEFYTP ELARIVTRSAGLL+A I E+GALEIA+RSRGTPRIANRLLRRV Sbjct: 182 LRDRFGIVARLEFYTPTELARIVTRSAGLLDARIAEDGALEIAKRSRGTPRIANRLLRRV 241 Query: 238 RDYAEVKGEGRITREMADAALVMLDVDPVGFDLMDRKLLEAVLFKFGGGPVGLDNLAAAI 297 RDYAEVK +G ITR +ADAAL MLDVD VGFDLMDRKLLEA+L KF GGPVG+DNLAAAI Sbjct: 242 RDYAEVKADGVITRAVADAALAMLDVDAVGFDLMDRKLLEAILHKFNGGPVGIDNLAAAI 301 Query: 298 GEERDTIEDVLEPYLIQQGYLQRTPRGRIATGLAYQHFGVTAPQTGPNGELW 349 GEERDTIEDVLEPYLIQQGYLQRTPRGR+AT AYQHFG+ AP+TGP +LW Sbjct: 302 GEERDTIEDVLEPYLIQQGYLQRTPRGRVATASAYQHFGLGAPKTGPARDLW 353 >NMA1412 [L] COG2255 Holliday junction resolvasome, helicase subunit NmA Neisseria meningitidis Z2491 Length = 343 Score = 513 bits (1321), Expect = e-145, Method: Compositional matrix adjust. Identities = 258/338 (76%), Positives = 292/338 (86%), Gaps = 3/338 (0%) Query: 3 IQTDDFSE---QRIISATPASANEEAVERALRPKQLDEYVGQEKVRSQLEIFISAARKRG 59 +QTD+ + QRI++A ASA EE +ERALRPK LD+Y+GQ K + QL IFI AA+KRG Sbjct: 2 LQTDNLTAAQPQRIVAAQTASAQEELLERALRPKTLDDYIGQHKAKEQLAIFIQAAKKRG 61 Query: 60 EPLDHTLLFGPPGLGKTTMAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFI 119 E LDH LLFGPPGLGKTT+AHIIA+E+GVNLRQTSGPVLERAGDLAALLTNL+ +DVLFI Sbjct: 62 EALDHVLLFGPPGLGKTTLAHIIAKELGVNLRQTSGPVLERAGDLAALLTNLDPHDVLFI 121 Query: 120 DEIHRMSPVVEEILYPALEDYQIDIMIGEGPAARSVRLDLQPFTLVGATTRAGMLTNPLR 179 DEIHR+SPVVEEILYPALEDY++DIMIGEGPAARSV++DL PFTLVGATTRAGMLTNPLR Sbjct: 122 DEIHRLSPVVEEILYPALEDYRLDIMIGEGPAARSVKIDLPPFTLVGATTRAGMLTNPLR 181 Query: 180 DRFGIVARLEFYTPPELARIVTRSAGLLNAPIVEEGALEIARRSRGTPRIANRLLRRVRD 239 DRFGIV+RLEFY +LA IV+RSA LL + EEGA EIA+RSRGTPRIANRLLRRVRD Sbjct: 182 DRFGIVSRLEFYENRDLATIVSRSAQLLQLDMSEEGAEEIAKRSRGTPRIANRLLRRVRD 241 Query: 240 YAEVKGEGRITREMADAALVMLDVDPVGFDLMDRKLLEAVLFKFGGGPVGLDNLAAAIGE 299 +A+VK G I +ADAAL MLDVD G D+MDRK LEAVL KFGGGPVGLDN+AAAIGE Sbjct: 242 FADVKNNGTIDGGIADAALSMLDVDVQGLDVMDRKFLEAVLHKFGGGPVGLDNVAAAIGE 301 Query: 300 ERDTIEDVLEPYLIQQGYLQRTPRGRIATGLAYQHFGV 337 DTIEDV+EPYLIQQG+LQRTPRGR+AT AY HFG+ Sbjct: 302 STDTIEDVIEPYLIQQGFLQRTPRGRMATERAYLHFGL 339 >NMB1243 [L] COG2255 Holliday junction resolvasome, helicase subunit Nme Neisseria meningitidis MC58 Length = 343 Score = 512 bits (1319), Expect = e-145, Method: Compositional matrix adjust. Identities = 256/338 (75%), Positives = 292/338 (86%), Gaps = 3/338 (0%) Query: 3 IQTDDFSE---QRIISATPASANEEAVERALRPKQLDEYVGQEKVRSQLEIFISAARKRG 59 +QTD+ + QRI++A ASA EE +ERALRPK LD+Y+GQ+K + QL IFI AA+KRG Sbjct: 2 LQTDNLTAAQPQRIVAAQTASAQEELLERALRPKTLDDYIGQDKAKEQLAIFIQAAKKRG 61 Query: 60 EPLDHTLLFGPPGLGKTTMAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFI 119 E LDH LLFGPPGLGKTT+AHIIA+E+GVNLRQTSGPVLERAGDLAALLTNL+ +DVLFI Sbjct: 62 EALDHVLLFGPPGLGKTTLAHIIAKELGVNLRQTSGPVLERAGDLAALLTNLDPHDVLFI 121 Query: 120 DEIHRMSPVVEEILYPALEDYQIDIMIGEGPAARSVRLDLQPFTLVGATTRAGMLTNPLR 179 DEIHR+SPVVEEILYPALEDY++DIMIGEGPAARSV++DL PFTL+GATTRAGMLTNPLR Sbjct: 122 DEIHRLSPVVEEILYPALEDYRLDIMIGEGPAARSVKIDLPPFTLIGATTRAGMLTNPLR 181 Query: 180 DRFGIVARLEFYTPPELARIVTRSAGLLNAPIVEEGALEIARRSRGTPRIANRLLRRVRD 239 DRFGIV+RLEFY +L IV+RSA LL + EEGA EIA+RSRGTPRIANRLLRRVRD Sbjct: 182 DRFGIVSRLEFYENRDLTTIVSRSAQLLQLDMSEEGAEEIAKRSRGTPRIANRLLRRVRD 241 Query: 240 YAEVKGEGRITREMADAALVMLDVDPVGFDLMDRKLLEAVLFKFGGGPVGLDNLAAAIGE 299 +A+VK G I +ADAAL MLDVD G D+MDRK LEAVL KFGGGPVGLDN+AAAIGE Sbjct: 242 FADVKNNGTIDGGIADAALSMLDVDAQGLDVMDRKFLEAVLHKFGGGPVGLDNVAAAIGE 301 Query: 300 ERDTIEDVLEPYLIQQGYLQRTPRGRIATGLAYQHFGV 337 DTIEDV+EPYLIQQG+LQRTPRGR+AT AY HFG+ Sbjct: 302 STDTIEDVIEPYLIQQGFLQRTPRGRMATERAYLHFGL 339 >VC1845 [L] COG2255 Holliday junction resolvasome, helicase subunit Vch Vibrio cholerae Length = 334 Score = 481 bits (1239), Expect = e-136, Method: Compositional matrix adjust. Identities = 234/316 (74%), Positives = 272/316 (86%) Query: 22 NEEAVERALRPKQLDEYVGQEKVRSQLEIFISAARKRGEPLDHTLLFGPPGLGKTTMAHI 81 +EE ++RA+RPK+L +Y GQ+ VR Q+EIFI AA+ R E LDH L+FGPPGLGKTT+A+I Sbjct: 17 DEEVIDRAIRPKKLADYQGQDHVRDQMEIFIQAAQMRQEALDHLLIFGPPGLGKTTLANI 76 Query: 82 IAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRMSPVVEEILYPALEDYQ 141 +A EMGVN+R TSGPVLE+AGDLAALLTNLE NDVLFIDEIHR+SP+VEE+LYPA+EDYQ Sbjct: 77 VANEMGVNIRTTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPMVEEVLYPAMEDYQ 136 Query: 142 IDIMIGEGPAARSVRLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTPPELARIVT 201 +DIMIGEGPAARS+++DL PFTL+GATTRAG LT+PLRDRFGIV RLE+Y +L IV Sbjct: 137 LDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEYYKVADLQHIVQ 196 Query: 202 RSAGLLNAPIVEEGALEIARRSRGTPRIANRLLRRVRDYAEVKGEGRITREMADAALVML 261 RSA L + EGALE+ARR+RGTPRIANRLLRRVRDYAEVKG+G I + AD AL ML Sbjct: 197 RSAQCLGLSMDSEGALEVARRARGTPRIANRLLRRVRDYAEVKGDGHICAQTADRALNML 256 Query: 262 DVDPVGFDLMDRKLLEAVLFKFGGGPVGLDNLAAAIGEERDTIEDVLEPYLIQQGYLQRT 321 DVD GFD MDRKLL A++ KF GGPVG+DNLAAAIGEE+DTIEDVLEP+LIQQGYLQRT Sbjct: 257 DVDHQGFDYMDRKLLLAIMEKFSGGPVGIDNLAAAIGEEKDTIEDVLEPFLIQQGYLQRT 316 Query: 322 PRGRIATGLAYQHFGV 337 PRGRIAT AY HFG+ Sbjct: 317 PRGRIATDRAYLHFGI 332 >STM1894 [L] COG2255 Holliday junction resolvasome, helicase subunit Sty Salmonella typhimurium LT2 Length = 336 Score = 479 bits (1234), Expect = e-135, Method: Compositional matrix adjust. Identities = 240/330 (72%), Positives = 285/330 (86%), Gaps = 1/330 (0%) Query: 12 RIISATPASANEEAVERALRPKQLDEYVGQEKVRSQLEIFISAARKRGEPLDHTLLFGPP 71 R+ISA A+ E+ +RA+RPK L EYVGQ +VRSQ+EIFI AA++RG+ LDH L+FGPP Sbjct: 6 RLISAG-ATIAEDVADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKRRGDALDHLLIFGPP 64 Query: 72 GLGKTTMAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRMSPVVEE 131 GLGKTT+A+I+A EMGVNLR TSGPVLE+AGDLAA+LTNLE +DVLFIDEIHR+SPVVEE Sbjct: 65 GLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEE 124 Query: 132 ILYPALEDYQIDIMIGEGPAARSVRLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFY 191 +LYPA+EDYQ+DIMIGEGPAARS+++DL PFTL+GATTRAG LT+PLRDRFGIV RLEFY Sbjct: 125 VLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFY 184 Query: 192 TPPELARIVTRSAGLLNAPIVEEGALEIARRSRGTPRIANRLLRRVRDYAEVKGEGRITR 251 P+L IV RSA + + ++GALE+ARR+RGTPRIANRLLRRVRD+AEVK +G I+ Sbjct: 185 QVPDLQHIVGRSARHMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGAISA 244 Query: 252 EMADAALVMLDVDPVGFDLMDRKLLEAVLFKFGGGPVGLDNLAAAIGEERDTIEDVLEPY 311 E+A AL ML+VD GFD MDRKLL AV+ KF GGPVGLDNLAAAIGEER+TIEDVLEPY Sbjct: 245 EIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPY 304 Query: 312 LIQQGYLQRTPRGRIATGLAYQHFGVTAPQ 341 LIQQG+LQRTPRGR+AT A+ HFG+T P+ Sbjct: 305 LIQQGFLQRTPRGRMATVRAWNHFGITPPE 334