BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0019.p (212 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value XF0167 [M] COG0739 Membrane proteins related to metalloendopepti... 201 8e-52 PA0667 [M] COG0739 Membrane proteins related to metalloendopepti... 192 5e-49 NMB0315 [M] COG0739 Membrane proteins related to metalloendopept... 177 2e-44 NMA2172 [M] COG0739 Membrane proteins related to metalloendopept... 176 3e-44 RC0557 [M] COG0739 Membrane proteins related to metalloendopepti... 161 1e-39 >XF0167 [M] COG0739 Membrane proteins related to metalloendopeptidases Xfa Xylella fastidiosa 9a5c Length = 417 Score = 201 bits (512), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 99/191 (51%), Positives = 127/191 (66%), Gaps = 5/191 (2%) Query: 1 VLAGEFDNAGNRYQAVWFSDPASKTGGGGYYAFDGKSLKKAFLKSPLAFTRISSGFSMRL 60 +LA F+ G Y + F + G Y+ DG+ LKK+F++ P+++ R+SS F +R Sbjct: 203 ILAATFNTGGKIYSGMRFM----RDGKVEYFDKDGRPLKKSFIRMPISYARLSSTFGLRR 258 Query: 61 HPILGQWKQHTGVDFAAPTGTPIHAAADGVVDFVGQQNGYGNIVVIKHWSGYSTAYGHMS 120 HPILG + H GVD+AA TGTPI AA D V F+GQQ GYGN+V++ H GY T YGHMS Sbjct: 259 HPILGTMRMHKGVDYAAATGTPIMAAGDARVQFIGQQRGYGNVVILNHGKGYRTLYGHMS 318 Query: 121 RFAPNIKKGMKVSQNDVIGFVGMTGWATGPHLHYEFRVNNQPRNPLSVEVPNNQALTGPQ 180 RF IK G K++Q VIG+VGMTG ATGPHLHYEF+VN Q RNPLS+ +P + L G Sbjct: 319 RFG-KIKAGQKINQGTVIGYVGMTGLATGPHLHYEFQVNGQHRNPLSITMPPPEPLRGKD 377 Query: 181 LQRFRTVAADM 191 L FRT A + Sbjct: 378 LIAFRTQTAPL 388 >PA0667 [M] COG0739 Membrane proteins related to metalloendopeptidases Pae Pseudomonas aeruginosa Length = 447 Score = 192 bits (488), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 97/196 (49%), Positives = 125/196 (63%), Gaps = 4/196 (2%) Query: 1 VLAGEFDNAGNRYQAVWFSDPASKTGGGGYYAFDGKSLKKAFLKSPLAFTRISSGFSM-R 59 +LA F N G Y AV +++ K G YY DG S++KAF+++P+ F RISS FS+ R Sbjct: 241 ILAARFVNRGKTYTAVRYTN---KQGNTSYYRADGSSMRKAFIRTPVDFARISSRFSLGR 297 Query: 60 LHPILGQWKQHTGVDFAAPTGTPIHAAADGVVDFVGQQNGYGNIVVIKHWSGYSTAYGHM 119 HPIL + + H GVD+AAP GTPI A DG + G++ GYGN VVI+H Y T YGHM Sbjct: 298 RHPILNKIRAHKGVDYAAPIGTPIKATGDGKILEAGRKGGYGNAVVIQHGQRYRTIYGHM 357 Query: 120 SRFAPNIKKGMKVSQNDVIGFVGMTGWATGPHLHYEFRVNNQPRNPLSVEVPNNQALTGP 179 SRFA I+ G V Q +IG+VGMTG ATGPHLHYEF++N + +PLS ++P L G Sbjct: 358 SRFAKGIRAGTSVKQGQIIGYVGMTGLATGPHLHYEFQINGRHVDPLSAKLPMADPLGGA 417 Query: 180 QLQRFRTVAADMQHRM 195 +RF M RM Sbjct: 418 DRKRFMAQTQPMIARM 433 >NMB0315 [M] COG0739 Membrane proteins related to metalloendopeptidases Nme Neisseria meningitidis MC58 Length = 430 Score = 177 bits (449), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 89/177 (50%), Positives = 115/177 (64%), Gaps = 11/177 (6%) Query: 1 VLAGEFDNAGNRYQAVWFSDPASKTGGGGYYAFDGKSL--KKAFLKSPLAFTRISSGFSM 58 +LA E G R+QA ++ GGG YY DGK L K F PL +TRISS F Sbjct: 224 ILAAEVVKGGTRHQAFYYRSDKEGGGGGNYYDEDGKVLQEKGGFNIEPLVYTRISSPFGY 283 Query: 59 RLHPILGQWKQHTGVDFAAPTGTPIHAAADGVVDFVGQQNGYGNIVVIKHWSGYSTAYGH 118 R+HPIL W+ HTG+D+AAP GTP+ A+ADGV+ F G++ GYGN V+I+H +G T Y H Sbjct: 284 RMHPILHTWRLHTGIDYAAPQGTPVRASADGVITFKGRKGGYGNAVMIRHANGVETLYAH 343 Query: 119 MSRFAP---NIKKGMKVSQNDVIGFVGMTGWATGPHLHYEFRVNNQPRNPLSVEVPN 172 +S F+ N++ G +VIGFVG TG +TGPHLHYE R+N QP NP+SV +P Sbjct: 344 LSAFSQAEGNVRGG------EVIGFVGSTGRSTGPHLHYEARINGQPVNPVSVALPT 394 >NMA2172 [M] COG0739 Membrane proteins related to metalloendopeptidases NmA Neisseria meningitidis Z2491 Length = 430 Score = 176 bits (446), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 88/177 (49%), Positives = 115/177 (64%), Gaps = 11/177 (6%) Query: 1 VLAGEFDNAGNRYQAVWFSDPASKTGGGGYYAFDGKSL--KKAFLKSPLAFTRISSGFSM 58 +LA E G R+QA ++ GGG YY DG+ L K F PL +TRISS F Sbjct: 224 ILAAEVVKGGTRHQAFYYRSDKEGGGGGNYYDEDGRVLQEKGGFNIEPLVYTRISSPFGY 283 Query: 59 RLHPILGQWKQHTGVDFAAPTGTPIHAAADGVVDFVGQQNGYGNIVVIKHWSGYSTAYGH 118 R+HPIL W+ HTG+D+AAP GTP+ A+ADGV+ F G++ GYGN V+I+H +G T Y H Sbjct: 284 RMHPILHTWRLHTGIDYAAPQGTPVRASADGVITFKGRKGGYGNAVMIRHANGVETLYAH 343 Query: 119 MSRFAP---NIKKGMKVSQNDVIGFVGMTGWATGPHLHYEFRVNNQPRNPLSVEVPN 172 +S F+ N++ G +VIGFVG TG +TGPHLHYE R+N QP NP+SV +P Sbjct: 344 LSAFSQAEGNVRGG------EVIGFVGSTGRSTGPHLHYEARINGQPVNPVSVALPT 394 >RC0557 [M] COG0739 Membrane proteins related to metalloendopeptidases Rco Rickettsia conorii Length = 476 Score = 161 bits (407), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 78/192 (40%), Positives = 117/192 (60%), Gaps = 1/192 (0%) Query: 1 VLAGEFDNAGNRYQAVWFSDPASKTGGGGYYAFDGKSLKKAFLKSPLAFTRISSGFSMRL 60 +L + +G Y +S + +++ DGKS+K++ LK+PL ++SS + R Sbjct: 266 ILYVSLNLSGKEYNIYRYSHD-NNANNHAFFSEDGKSVKRSLLKTPLKVIKVSSHYGNRK 324 Query: 61 HPILGQWKQHTGVDFAAPTGTPIHAAADGVVDFVGQQNGYGNIVVIKHWSGYSTAYGHMS 120 HPILG K H GVDFAAPTGTPI++A +GV+ +G ++GYG + +KH STAY H S Sbjct: 325 HPILGYTKMHRGVDFAAPTGTPIYSAGNGVITEIGWKSGYGKFIQVKHSGTLSTAYAHAS 384 Query: 121 RFAPNIKKGMKVSQNDVIGFVGMTGWATGPHLHYEFRVNNQPRNPLSVEVPNNQALTGPQ 180 FA N+K G V Q +I +VG TG AT PHLHYE +++ + NP+SV+ L G Sbjct: 385 NFAKNLKVGSIVKQGQIIAYVGSTGRATAPHLHYEVKIDGKHVNPMSVKTTPGIELNGKN 444 Query: 181 LQRFRTVAADMQ 192 L++F+ +++ Sbjct: 445 LEKFKQFKKEIK 456