BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0065.p (199 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEI1235 [IQR] COG1028 Dehydrogenases with different specificiti... 324 7e-89 AGc2465 [IQR] COG1028 Dehydrogenases with different specificitie... 313 2e-85 mll1830 [IQR] COG1028 Dehydrogenases with different specificitie... 295 4e-80 SMc00136 [IQR] COG1028 Dehydrogenases with different specificiti... 289 2e-78 TM1724 [IQR] COG1028 Dehydrogenases with different specificities... 119 3e-27 >BMEI1235 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Bme Brucella melitensis Length = 241 Score = 324 bits (831), Expect = 7e-89, Method: Compositional matrix adjust. Identities = 151/198 (76%), Positives = 167/198 (84%) Query: 2 SSKVALFQRXLGGIGVTGSNQSVDDLQKLVDQAVARWGRVDVLVNSAGHGPRAPILDITD 61 S K + LGGIGVTGSNQS DDLQKLVDQ + +WGR+DVLVNSAGHGPRAPIL+ITD Sbjct: 44 SGKGEALAKELGGIGVTGSNQSNDDLQKLVDQTLEKWGRIDVLVNSAGHGPRAPILEITD 103 Query: 62 EDWHRGMDTYLLNVIRPTRLVTPLMQAQGGGAIINISSAWAFEPSDMFPTSAVFRAGLAA 121 EDWH+GMDTY LN +RP RLV P MQ Q G IINIS+AWAFEPS MFPTSAVFRAGLA+ Sbjct: 104 EDWHKGMDTYFLNAVRPARLVVPAMQKQKSGVIINISTAWAFEPSAMFPTSAVFRAGLAS 163 Query: 122 FIKLFADKYAPENIRINNVLPGWIDSLPQREERRAGVPMQRYGTSEEVAATIAFLASSGA 181 F K+FAD YA ENIR+NNVLPGWIDSLP EERR VPMQRYG SEE+AAT++FLAS GA Sbjct: 164 FTKIFADTYAAENIRMNNVLPGWIDSLPTTEERRESVPMQRYGKSEEIAATVSFLASDGA 223 Query: 182 GYITGQNIKVDGGLMRSV 199 YITGQN++VDGGL RSV Sbjct: 224 AYITGQNLRVDGGLTRSV 241 >AGc2465 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 248 Score = 313 bits (801), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 146/198 (73%), Positives = 167/198 (84%) Query: 2 SSKVALFQRXLGGIGVTGSNQSVDDLQKLVDQAVARWGRVDVLVNSAGHGPRAPILDITD 61 S K + LGGIGVTGSNQS DDLQ+L DQ + ++GR+DVLVNSAGHGPRA ILDITD Sbjct: 51 SGKGEALAKELGGIGVTGSNQSNDDLQRLTDQTLEKFGRIDVLVNSAGHGPRASILDITD 110 Query: 62 EDWHRGMDTYLLNVIRPTRLVTPLMQAQGGGAIINISSAWAFEPSDMFPTSAVFRAGLAA 121 E WH G+D YL+NVIRPTR+V P+M Q GAI+NIS+AWAFEPS MFPTSAVFRAGLA+ Sbjct: 111 EQWHTGLDVYLMNVIRPTRIVAPIMVKQKAGAIVNISTAWAFEPSSMFPTSAVFRAGLAS 170 Query: 122 FIKLFADKYAPENIRINNVLPGWIDSLPQREERRAGVPMQRYGTSEEVAATIAFLASSGA 181 + K+FAD YA +N+R+NNVLPGWIDSLP EERR VPMQRYG SEE+AAT+AFLAS GA Sbjct: 171 YSKIFADTYAADNVRMNNVLPGWIDSLPATEERRDSVPMQRYGKSEEIAATVAFLASEGA 230 Query: 182 GYITGQNIKVDGGLMRSV 199 GYITGQNI+VDGGL RSV Sbjct: 231 GYITGQNIRVDGGLTRSV 248 >mll1830 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 234 Score = 295 bits (755), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 139/198 (70%), Positives = 163/198 (82%) Query: 2 SSKVALFQRXLGGIGVTGSNQSVDDLQKLVDQAVARWGRVDVLVNSAGHGPRAPILDITD 61 S K + LGG+GVTGSNQS DDLQ+L D + R+GR+DVLVNS GHGPRAPIL+ITD Sbjct: 37 SGKGEALAKELGGLGVTGSNQSSDDLQRLADLTLERFGRIDVLVNSGGHGPRAPILEITD 96 Query: 62 EDWHRGMDTYLLNVIRPTRLVTPLMQAQGGGAIINISSAWAFEPSDMFPTSAVFRAGLAA 121 E W GMD YL+NVIRP R+V P M Q GGAIINIS+AW EP+ MFPTSAVFRAG+ A Sbjct: 97 EQWRTGMDVYLMNVIRPVRIVAPQMVKQKGGAIINISTAWVAEPNVMFPTSAVFRAGVTA 156 Query: 122 FIKLFADKYAPENIRINNVLPGWIDSLPQREERRAGVPMQRYGTSEEVAATIAFLASSGA 181 + K+F++ YA +N+R+NNVLPGWIDSLP EERR VPMQRYGTSEEVAATIAFLAS GA Sbjct: 157 YTKIFSNTYAADNVRMNNVLPGWIDSLPTVEERRDNVPMQRYGTSEEVAATIAFLASEGA 216 Query: 182 GYITGQNIKVDGGLMRSV 199 GYITGQNI+VDGG++R++ Sbjct: 217 GYITGQNIRVDGGVIRAL 234 >SMc00136 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 234 Score = 289 bits (740), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 136/198 (68%), Positives = 160/198 (80%) Query: 2 SSKVALFQRXLGGIGVTGSNQSVDDLQKLVDQAVARWGRVDVLVNSAGHGPRAPILDITD 61 S K + LGGIGVTGSNQS DDL++LVD A WGRVD L+NSAGHGPRAP+L++TD Sbjct: 37 SGKGEALAKELGGIGVTGSNQSNDDLKRLVDTAYDAWGRVDALINSAGHGPRAPVLELTD 96 Query: 62 EDWHRGMDTYLLNVIRPTRLVTPLMQAQGGGAIINISSAWAFEPSDMFPTSAVFRAGLAA 121 E+WHRGMD Y LNV+RPTRLVTP+M Q G+I+NIS+ AFEP +FPTS VFR+GLAA Sbjct: 97 EEWHRGMDVYFLNVVRPTRLVTPIMVEQKSGSIVNISTYAAFEPDPLFPTSGVFRSGLAA 156 Query: 122 FIKLFADKYAPENIRINNVLPGWIDSLPQREERRAGVPMQRYGTSEEVAATIAFLASSGA 181 F KLFAD+YA +NIR+NNVLPG+IDSLP+ EERR +PM RYG SEEVA IA LAS Sbjct: 157 FTKLFADRYAADNIRMNNVLPGFIDSLPETEERRRRIPMGRYGASEEVAELIALLASDRG 216 Query: 182 GYITGQNIKVDGGLMRSV 199 GYITGQNI++DGG+ RSV Sbjct: 217 GYITGQNIRIDGGITRSV 234 >TM1724 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Tma Thermotoga maritima Length = 246 Score = 119 bits (299), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 67/179 (37%), Positives = 106/179 (59%), Gaps = 7/179 (3%) Query: 25 DDLQKLVDQAVARWGRVDVLVNSAGHGPRAPILDITDEDWHRGMDTYLLNVIRPTRLVTP 84 D ++++V++ V ++GR+DVLVN+AG A ++ + +EDW ++ L V T++V P Sbjct: 67 DQIKEVVEKVVQKYGRIDVLVNNAGITRDALLVRMKEEDWDAVINVNLKGVFNVTQMVVP 126 Query: 85 LMQAQGGGAIINISSAWAFEPSDMFPTSAVFRAGLAAFIKLFADKYAPENIRINNVLPGW 144 M Q G+I+N+SS + A +AG+ K +A + A NIR+N V PG+ Sbjct: 127 YMIKQRNGSIVNVSSVVGIYGNPGQTNYAASKAGVIGMTKTWAKELAGRNIRVNAVAPGF 186 Query: 145 IDS-----LPQ--REERRAGVPMQRYGTSEEVAATIAFLASSGAGYITGQNIKVDGGLM 196 I++ LP+ RE + +P+ R+G EEVA I FLAS + Y+TGQ I +DGGL+ Sbjct: 187 IETPMTEKLPEKARETALSRIPLGRFGKPEEVAQVILFLASDESSYVTGQVIGIDGGLV 245