BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0055.p (288 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc5105 [R] COG3618 Predicted metal-dependent hydrolase of the T... 152 8e-37 mll5767 Non COG 85 2e-16 mlr1708 Non COG 83 9e-16 AGl2610 [R] COG3618 Predicted metal-dependent hydrolase of the T... 76 8e-14 BMEI1718 [R] COG3618 Predicted metal-dependent hydrolase of the ... 75 1e-13 >AGc5105 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 287 Score = 152 bits (384), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 97/284 (34%), Positives = 145/284 (51%), Gaps = 17/284 (5%) Query: 6 IDAHQHFWRYRADDYPWIGKGMELLACDRLPGQLHPVLDAEGLQSSIAVQARVGREETGF 65 IDAHQHFW + W + + D LP L P+L A G+ ++ VQ +T F Sbjct: 17 IDAHQHFWLMKDRAGQWPPPSLAAIYRDFLPTDLSPLLTAAGVSGTVLVQTMETAADTDF 76 Query: 66 LLDLARADRRIAGVVGWEDLSSPHLAANVAQWGRDK-LVGFRHQIQDEADVMAFVEAPAF 124 +L+LA I GVVGW D+ S + A +A+ + G R +Q DV A+++ A Sbjct: 77 MLELAENTDFIKGVVGWVDMKSAEVTAEIARRAKHPAFKGVRPMLQGMEDV-AWIDDAAL 135 Query: 125 NAGIKWLQQQGLVYDVLIHARQMAEVQAFCARHDRHWLVLDHLGKPALVDFGRSEASFNG 184 NA ++ L + GLV+D L+ + + +F ++H +V+DH KP + + + Sbjct: 136 NAAVEALVKHGLVFDALVLPPNLPHLLSFASKHPELPVVIDHGAKPLI-----ATGHYRD 190 Query: 185 WKRQLRALAAMPHVACKLSGLVTEADWLRGLRQKDYDNIALCLDTALEAFGPQRLMFGSD 244 W+R + ALAA P+V CKLSGL+TE R + Y +T LE FG R++FGSD Sbjct: 191 WRRNMAALAARPNVHCKLSGLLTERGEQRPEAVRPY------AETILELFGGDRVIFGSD 244 Query: 245 WPVCLLAASYATVAGVVREWAATRLSAAEQEQLWGGTAARCYGL 288 WPV LA + R+ + A + ++GG A R Y L Sbjct: 245 WPVLRLAGDFQGWLDFCRDI----VPAKDHAAVFGGNAIRFYSL 284 >mll5767 Non COG Length = 297 Score = 84.7 bits (208), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 85/305 (27%), Positives = 131/305 (42%), Gaps = 36/305 (11%) Query: 6 IDAHQHFWRYRADDYPWIGKGMELLACD-----RLPGQLHPVL-DAEGLQSSIAVQARVG 59 ID H H W + YPW+ G++ A R +L L DA +V VG Sbjct: 7 IDPHHHLWDLEVNYYPWLTDGVKPSAFGDYEAIRTNYRLDDYLEDARNQNLVKSVHLDVG 66 Query: 60 RE------ETGFLLDLARADRRIAGVVGWEDLSSPHLAANVAQ-WGRDKLVGFRHQIQDE 112 + ET +L ++A G+VG+ DLS P + + + G R + Sbjct: 67 FDPSDPVGETRWLQEIANKRGFPHGIVGYADLSKPDVGELLDRHMEYPNFRGIRQSMNYH 126 Query: 113 ADVMAFVEA-------PAFNAGIKWLQQQGLVYDVLIHARQMAEVQAFCARHDRHWLVLD 165 AD +A P + G + L ++ L +D+ ++ QM E ++L+ Sbjct: 127 ADPAKTYQARPEVSRTPEWRRGFRELAKRRLSFDLQLYYPQMEEFLQLAHDFPDVQIILN 186 Query: 166 HLGKPALVDFGRSEASFNGWKRQLRALAAMPHVACKLSGL-VTEADWLRGLRQKDYDNIA 224 H G VD FN WK+ + LA P+VACK+SGL + + W +I Sbjct: 187 HTG--MQVD---GPKHFNAWKKGMHRLAQAPNVACKISGLGMGDWSWTTA-------SIR 234 Query: 225 LCLDTALEAFGPQRLMFGSDWPVCLLAASYATVAGVVREWAATRLSAAEQE-QLWGGTAA 283 ++ A+ AFG R MF +++PV L +S+ V +E TR E+ L+ AA Sbjct: 235 PYVEEAIAAFGVGRSMFATNFPVDKLFSSFDAVVNAFKE--ITRYYPHEERLALFHDNAA 292 Query: 284 RCYGL 288 R Y L Sbjct: 293 RHYRL 297 >mlr1708 Non COG Length = 295 Score = 82.8 bits (203), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 81/301 (26%), Positives = 125/301 (41%), Gaps = 33/301 (10%) Query: 6 IDAHQHFWRYRADDYPWIGKGM--------ELLACDRLPGQLHPVLDAEGLQSSIAVQAR 57 IDAH H WR + D PW+ M E + D G+ G++ ++ VQ Sbjct: 5 IDAHFHIWRQK--DQPWLVGPMVPRIFGPYEPIRRDYPIGEFLQDQKGSGVEKAVYVQTN 62 Query: 58 VGRE----ETGFLLDLARADRRIAGVVGWEDLSSPHLAANVAQWGRDKLV-GFRHQIQ-D 111 +E E FL A +VG+ D++ + + + + +L+ G R Q+ Sbjct: 63 WAKEDFEKEVAFLQQTADETGWPHAIVGYADMTVDDVRPQIDRLMKYRLLRGVRMQLHWH 122 Query: 112 EADVMAF------VEAPAFNAGIKWLQQQGLVYDVLIHARQMAEVQAFCARHDRHWLVLD 165 E F V P A + L+ GL +D+ + QM + + +L Sbjct: 123 ETPAFRFAASADQVIDPKVRANVARLKDYGLSFDLQLFPAQMKDGVTLVGENPETNFILT 182 Query: 166 HLGKPALVDFGRSEASFNGWKRQLRALAAMPHVACKLSGLVTEADWLRGLRQKDYDNIAL 225 H G G WK LR L+A P+ KLSGL T + + D IA Sbjct: 183 HAGMLT----GMEPEVTETWKAGLRTLSAAPNFYAKLSGLGT------FVHRNDPALIAY 232 Query: 226 CLDTALEAFGPQRLMFGSDWPVCLLAASYATVAGVVREWAATRLSAAEQEQLWGGTAARC 285 +D A++ G LMFGS++P+ L S+A + R+ A +AAE + W TA + Sbjct: 233 IVDNAIDILGADHLMFGSNFPIEKLWTSHAELIKAHRDAVARHGAAAEADIFW-NTAEKV 291 Query: 286 Y 286 Y Sbjct: 292 Y 292 >AGl2610 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 297 Score = 76.3 bits (186), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 77/294 (26%), Positives = 123/294 (41%), Gaps = 33/294 (11%) Query: 6 IDAHQHFWRYRADDYPWIGKGMELLACDRLPGQLHPVLDAEGLQSSIAVQARVGREETGF 65 ID HQH Y W +G LA +++ G+ +I + ETG Sbjct: 21 IDTHQHLILRGKLGYAWT-RGEPSLAGSFTRADYAALVEGSGVIGTIFM-------ETGV 72 Query: 66 LLDLARADRR-IAGVVGWEDLS--------SPHLAANVAQWGRD----KLVGFRHQIQDE 112 RA+ R +AG+VG L P W + K+VGFR +Q Sbjct: 73 DDGDYRAEARLVAGMVGEGTLPMFGQIASCRPETDQGFDAWLEECRHLKVVGFRRILQVM 132 Query: 113 ADVMAFVEAPAFNAGIKWLQQQGLVYDVLIHARQMAEVQAFCARHDRHWLVLDHLGKPAL 172 D + E + ++ + + G D+ H+RQ+A +LDH G P + Sbjct: 133 PDDTSRAEN--YRRNVRKIGKAGWPVDLCFHSRQLAIAAELVRACPDVRFMLDHCGTPDI 190 Query: 173 VDFGRSEASFNGWKRQLRALAAMPHVACKLSGLVTEADWLRGLRQKDYDNIALCLDTALE 232 + F W ++ LA++P++ KLSG+ Q +++ ++T L+ Sbjct: 191 -----AGNDFPAWSERMADLASLPNLFVKLSGVTAYC----APGQVTLESVRPYVETVLK 241 Query: 233 AFGPQRLMFGSDWPVCLLAASYATVAGVVREWAATRLSAAEQEQLWGGTAARCY 286 FGP R+++G DWPV L + + RE+ +T LS EQ + G A R Y Sbjct: 242 LFGPARMVWGGDWPVVDLGSGLPEWIAMTREFLST-LSPDEQASIGHGNARRFY 294 >BMEI1718 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold Bme Brucella melitensis Length = 282 Score = 75.5 bits (184), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 77/297 (25%), Positives = 125/297 (42%), Gaps = 31/297 (10%) Query: 6 IDAHQHFWRYRADDYPWIGKGMELLACDRLPGQLHPVLDAEGLQSSIAVQARVG----RE 61 ID H H A YPW+ + L D L + G+ ++ ++ V + Sbjct: 3 IDTHLHLIDKNALSYPWL-ESAPALNRDFLFDSYRLQAERAGIGGALHIEVDVAPHAMQA 61 Query: 62 ETGFLLDLAR-ADRRIAGVVGWEDLSSPHLAANVAQWGRDKLV-GFR---HQIQDEADVM 116 ET + +AR + I G + P AA + + D V G R H + DE Sbjct: 62 ETDHIRQIARRSGGFIKGAIASCRPEEPGFAAYLERQLSDPFVKGLRRVLHVVPDEVS-- 119 Query: 117 AFVEAPAFNAGIKWLQQQGLVYDVLIHARQMAEVQAFCARHDRHWLVLDHLGKPALVDFG 176 E F IK L+ GL +D+ + Q+ + A ++DH G P + Sbjct: 120 ---EGALFRENIKRLEGTGLTFDLCVQPHQIGKAIALADLAPDLCFIVDHCGAPDI---- 172 Query: 177 RSEASFNGWKRQLRALAAMPHVACKLSGLVTEADWLRGLRQKDYDNIALCLDTALEAFGP 236 + +GW+ + ++ P+V K+SGLV D + + + +++FG Sbjct: 173 -KAGALDGWREGMAEISRRPNVIAKISGLVVYCD----AESWTVETLRPYAEQVIQSFGW 227 Query: 237 QRLMFGSDWPVCLLAASYATVAGVVREWAATR-----LSAAEQEQLWGGTAARCYGL 288 R+++GSDWPVC LA+S AG+ AAT S E+ +L+ A R + L Sbjct: 228 DRVIWGSDWPVCTLASS--PDAGLSTWVAATHALLEGCSTTEKSRLFCENARRIWNL 282