BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0022.p (427 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3478 [GC] COG1819 Glycosyl transferases, related to UDP-glucur... 214 3e-55 ML2348 [GC] COG1819 Glycosyl transferases, related to UDP-glucur... 89 2e-17 Rv1524 [GC] COG1819 Glycosyl transferases, related to UDP-glucur... 89 3e-17 MT1575 [GC] COG1819 Glycosyl transferases, related to UDP-glucur... 89 3e-17 Rv1526c [GC] COG1819 Glycosyl transferases, related to UDP-glucu... 86 2e-16 >PA3478 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase Pae Pseudomonas aeruginosa Length = 426 Score = 214 bits (545), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 147/393 (37%), Positives = 209/393 (53%), Gaps = 12/393 (3%) Query: 12 ILATTGTTGDMLPFLSLGLGLQARGHRV-LMVVPRFHAALFEQAGLSCHPLGSVEEFQAV 70 IL G+ GD+ PF+ L L+ RGHRV L +P F A+ EQ G++ PL ++ Sbjct: 4 ILIAIGSAGDVFPFIGLARTLKLRGHRVSLCTIPVFRDAV-EQHGIAFVPLSDELTYRRT 62 Query: 71 LANPDLWDERRGWQVICRAAVPYIDCLHQLVAQLPAEEECVILSHPLLVPAADIARTLRP 130 + +P LWD + + V+ +A I+ +++ V+ ++ V+ S L A IA + Sbjct: 63 MGDPRLWDPKTSFGVLWQAIAGMIEPVYEYVSAQRHDDIVVVGS--LWALGARIAHE-KY 119 Query: 131 GLRVVATYLAPSNLCSSHDLLAMGSLPVPGWLPLPWRKTLWSLAHRWMIDPPALPALNAV 190 G+ ++ ++PS L S+H VP +PL RK LW R+ +D P +NAV Sbjct: 120 GIPYLSAQVSPSTLLSAHLPPVHPKFNVPEQMPLAMRKLLWRCIERFKLDRTCAPEINAV 179 Query: 191 RARLGLP-PVAHFFAHVMQAPDASLGLFPDWFGAVQPDWPQPFLSGQFP---PPSPPSPS 246 R ++GL PV F M +P + LFP WF Q DWPQP FP P +P Sbjct: 180 RRKVGLETPVKRIFTQWMHSPQGVVCLFPAWFAPPQQDWPQPLHMTGFPLFDGSIPGTPL 239 Query: 247 DWTPALRQFLDYGPAPIVFTPGSGHQHAAQFFASAVRAAQALGRRALLVTRHREQLPAVL 306 D L++FLD G P+VFT GS F+A A+RA + LG R + +T ++ L Sbjct: 240 D--DELQRFLDQGSRPLVFTQGSTEHLQGDFYAMALRALERLGARGIFLTGAGQEPLRGL 297 Query: 307 PEGVLWQSYVSFDALLPEVAAIVHHGGIGTTAAALRAGVPQLVVPFAYDQFDNACRVRRL 366 P VL ++Y ALLP A +VH GGIG + AL AGVPQ+++P A+DQFDNA R+ RL Sbjct: 298 PNHVLQRAYAPLGALLPSCAGLVHPGGIGAMSLALAAGVPQVLLPCAHDQFDNAERLVRL 357 Query: 367 GVGDIIPAKRLSASRLQAALARLLAAPDVAQRC 399 G G + L L+ AL RLL P +A C Sbjct: 358 GCGMRLGVP-LREQELRGALWRLLEDPAMAAAC 389 >ML2348 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase Mle Mycobacterium leprae Length = 421 Score = 89.0 bits (219), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 130/419 (31%), Positives = 183/419 (43%), Gaps = 53/419 (12%) Query: 11 LILATTGTTGDMLPFLSLGLGLQARGHRVLMVVPRFHAALFEQAGLSCHPLG-SVEEFQA 69 LA +G+ GD+ PF +LGL LQ RGH V + VP E AGL+ G +EF A Sbjct: 3 FTLAASGSRGDVEPFAALGLELQRRGHEVRIGVPPDMLRFVESAGLAAVAYGPDTQEFLA 62 Query: 70 VLANPDLWDERRGWQVICRAAVPYIDCLHQLVAQLPAEEECVILSHPLLVPAADIARTLR 129 D + + R W I +P I L QL Q A+ + S L AD+ T Sbjct: 63 ----RDTYSQWRQWWKI----LPPIKALQQL-RQAWADMATDLKS---LADGADLVMTGV 110 Query: 130 PGLRVVAT----YLAPSNLCSSHDLLAMGSLPVPGWLPLPWRKTLWSLAHR--WMIDPPA 183 VVA Y P + H + A + + LP P + + + R W++ A Sbjct: 111 VYQGVVANVAEYYGIPFGVL--HFVPARVNGKIIPSLPSPLNRAILATVWRAHWLL---A 165 Query: 184 LPALNAVRARLGLPP--------VAHFFAHVMQAPDASL--GLFPDWFGAVQPDWPQPF- 232 +A R LGLP + A +QA D GL +W + +PF Sbjct: 166 KKPEDAQRRELGLPKATSLSTRRIVKRGALEIQAYDELCFPGLAAEW---AEYGDRRPFV 222 Query: 233 --LSGQFPPPSPPSPSDWTPALRQFLDYGPAPIVFTPGSGHQHAAQFFASAVRAAQA-LG 289 L+ + P + W A G PI F GS + + + AA A LG Sbjct: 223 GALTLELPTAADNEVLSWIAA-------GTPPIYFGFGSMPIVSPTDTVAMIAAACADLG 275 Query: 290 RRALLVTRHREQLPAVLPEGVLWQSYVSFDALLPEVAAIVHHGGIGTTAAALRAGVPQLV 349 RAL+ + ++ + V + VS A+ P A+VHHGG GTTAA+LRAGVP L+ Sbjct: 276 ERALISVKPKDLTQVPKFDHVKIVTSVSHAAVFPACRAVVHHGGAGTTAASLRAGVPTLI 335 Query: 350 VPFAYDQFDNACRVRRLGVGDIIPAKRLSAS--RLQAALARLLAAPDVAQRCHAIARSM 406 + +Q A +++RL VG +R SA+ R AA R + AP A R +A M Sbjct: 336 LWIFIEQPVWAAQIKRLKVG---AGRRFSATTQRSLAADLRTILAPQYATRAREVANRM 391 >Rv1524 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase Mtu Mycobacterium tuberculosis H37Rv Length = 414 Score = 88.6 bits (218), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 115/415 (27%), Positives = 181/415 (43%), Gaps = 44/415 (10%) Query: 11 LILATTGTTGDMLPFLSLGLGLQARGHRVLMVVPRFHAALFEQAGLSCHPLGSVEEFQAV 70 ++A+ GT GD+ P ++GL LQ RGH V + VP E AGLS GS + + + Sbjct: 3 FVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQL 62 Query: 71 LAN--PDLWDERRGWQVICRAAVPYIDCLHQLVAQLP---AEEECVILSHPLLVPAADIA 125 + W + +++ A P + +L A L A + ++ A++A Sbjct: 63 DEQFLHNAWKLQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADLLLTGQIYQEVVANVA 122 Query: 126 RTLRPGLRVVATYLAPSNLCSSHDLLAMGSLPVPGWLPLPW-RKTLWSLAHRWMIDPPAL 184 G+ + A + P + A G + P LP P R T+ ++ W+ Sbjct: 123 E--HHGIPLAALHFYP--------VRANGEIAFPARLPAPLVRSTITAI--DWLYWRMTK 170 Query: 185 PALNAVRARLGLPP--------VAHFFAHVMQAPDASL--GLFPDWFGAVQPDWPQPFLS 234 +A R LGLP +A + +QA DA GL +W G +PF+ Sbjct: 171 GVEDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDALCFPGLAAEWGG------RRPFVG 224 Query: 235 GQFPPPSPPSPSDWTPALRQFLDYGPAPIVFTPGSGHQHAAQFFASAVRAAQA-LGRRAL 293 + S +D + ++ PI F GS + + + AA A LG RAL Sbjct: 225 AL----TMESATDADDEVASWIAADTPPIYFGFGSMPIGSLADRVAMISAACAELGERAL 280 Query: 294 LVTRHREQLPAVLPEGVLWQSYVSFDALLPEVAAIVHHGGIGTTAAALRAGVPQLVVPFA 353 + + + + V VS A+ P A+VHHGG GTTAA LRAG+P L++ Sbjct: 281 ICSGPSDATGIPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVT 340 Query: 354 YDQFDNACRVRRLGVGDIIPAKRLSASRLQAALA--RLLAAPDVAQRCHAIARSM 406 DQ A ++++L VG +R S++ ++ +A R + APD R IA M Sbjct: 341 SDQPIWAAQIKQLKVGR---GRRFSSATKESLIADLRTILAPDYVTRAREIASRM 392 >MT1575 [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase MtC Mycobacterium tuberculosis CDC1551 Length = 414 Score = 88.6 bits (218), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 115/415 (27%), Positives = 181/415 (43%), Gaps = 44/415 (10%) Query: 11 LILATTGTTGDMLPFLSLGLGLQARGHRVLMVVPRFHAALFEQAGLSCHPLGSVEEFQAV 70 ++A+ GT GD+ P ++GL LQ RGH V + VP E AGLS GS + + + Sbjct: 3 FVVASYGTRGDIEPCAAVGLELQRRGHDVCLAVPPNLIGFVETAGLSAVAYGSRDSQEQL 62 Query: 71 LAN--PDLWDERRGWQVICRAAVPYIDCLHQLVAQLP---AEEECVILSHPLLVPAADIA 125 + W + +++ A P + +L A L A + ++ A++A Sbjct: 63 DEQFLHNAWKLQNPIKLLREAMAPVTEGWAELSAMLTPVAAGADLLLTGQIYQEVVANVA 122 Query: 126 RTLRPGLRVVATYLAPSNLCSSHDLLAMGSLPVPGWLPLPW-RKTLWSLAHRWMIDPPAL 184 G+ + A + P + A G + P LP P R T+ ++ W+ Sbjct: 123 E--HHGIPLAALHFYP--------VRANGEIAFPARLPAPLVRSTITAI--DWLYWRMTK 170 Query: 185 PALNAVRARLGLPP--------VAHFFAHVMQAPDASL--GLFPDWFGAVQPDWPQPFLS 234 +A R LGLP +A + +QA DA GL +W G +PF+ Sbjct: 171 GVEDAQRRELGLPKASTPAPRRMAVRGSLEIQAYDALCFPGLAAEWGG------RRPFVG 224 Query: 235 GQFPPPSPPSPSDWTPALRQFLDYGPAPIVFTPGSGHQHAAQFFASAVRAAQA-LGRRAL 293 + S +D + ++ PI F GS + + + AA A LG RAL Sbjct: 225 AL----TMESATDADDEVASWIAADTPPIYFGFGSMPIGSLADRVAMISAACAELGERAL 280 Query: 294 LVTRHREQLPAVLPEGVLWQSYVSFDALLPEVAAIVHHGGIGTTAAALRAGVPQLVVPFA 353 + + + + V VS A+ P A+VHHGG GTTAA LRAG+P L++ Sbjct: 281 ICSGPSDATGIPQFDHVKVVRVVSHAAVFPTCRAVVHHGGAGTTAAGLRAGIPTLILWVT 340 Query: 354 YDQFDNACRVRRLGVGDIIPAKRLSASRLQAALA--RLLAAPDVAQRCHAIARSM 406 DQ A ++++L VG +R S++ ++ +A R + APD R IA M Sbjct: 341 SDQPIWAAQIKQLKVGR---GRRFSSATKESLIADLRTILAPDYVTRAREIASRM 392 >Rv1526c [GC] COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase Mtu Mycobacterium tuberculosis H37Rv Length = 426 Score = 85.5 bits (210), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 124/427 (29%), Positives = 173/427 (40%), Gaps = 66/427 (15%) Query: 11 LILATTGTTGDMLPFLSLGLGLQARGHRVLMVVPRFHAALFEQAGLSCHPLG--SVEEFQ 68 +LA GT GD+ P ++G+ L+ RGH V M VP E AGL+ G S E+ Sbjct: 3 FVLAVHGTRGDVEPCAAVGVELRRRGHAVHMAVPPNLIEFVESAGLTGVAYGPDSDEQIN 62 Query: 69 AVLANPDLWDERRGWQVICRAAVPYIDCLHQLVAQLPAE---EECVILSHPLLVPAADIA 125 V A + + RA P L + V +L E E L+ L AD+ Sbjct: 63 TVAAF---------VRNLTRAQNPL--NLARAVKELFVEGWAEMGTTLT--TLADGADLV 109 Query: 126 RTLRPGLRVVATYLAPSNLCSSHDL---------------LAMGSLPVPGWLPLPWRKTL 170 T + V A N+ +D+ +A+ S+P P L K Sbjct: 110 MTGQTYHGVAA------NVAEYYDIPAAALHHFPMQVNGQIAIPSIPTPATLVRATMKVS 163 Query: 171 WSLAHRWMIDPPALPALNAVRARLGLPP--------VAHFFAHVMQAPDASLGLFPDWFG 222 W L D A A R LGLPP +A A +QA D P +F Sbjct: 164 WRLYAYVSKD-----ADRAQRRELGLPPAPAPAVRRLAERGAPEIQAYD------PVFFP 212 Query: 223 AVQPDWP--QPFLSGQFPPPSPPSPSDWTPALRQFLDYGPAPIVFTPGSG-HQHAAQFFA 279 + +W +PF+ P + S+ L ++ G PI F GS Q Q A Sbjct: 213 GLAAEWSDRRPFVG----PLTMELHSEPNEELESWIAAGTPPIYFGFGSTPVQTPVQTLA 268 Query: 280 SAVRAAQALGRRALLVTRHREQLPAVLPEGVLWQSYVSFDALLPEVAAIVHHGGIGTTAA 339 LG RAL+ + + V V++ +LP+ A+VHHGG GTTAA Sbjct: 269 MISDVCAQLGERALIYSPAANSTRIRHADHVKRVGLVNYSTILPKCRAVVHHGGAGTTAA 328 Query: 340 ALRAGVPQLVVPFAYDQFDNACRVRRLGVGDIIPAKRLSASRLQAALARLLAAPDVAQRC 399 LRAG+P L++ DQ A V+RL VG ++ L L +L AP+ A R Sbjct: 329 GLRAGMPTLILWDVADQPIWAGAVQRLKVGSAKRFTNITRGSLLKELRSIL-APECAARA 387 Query: 400 HAIARSM 406 I+ M Sbjct: 388 REISTRM 394