BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.5437.p (374 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777690.1| D-3-phosphoglycerate dehydrogenase [Herbaspi... 572 e-161 ref|YP_001355375.1| D-isomer specific 2-hydroxyacid dehydrogenas... 479 e-133 ref|YP_004755071.1| D-3-phosphoglycerate dehydrogenase [Collimon... 466 e-129 ref|YP_001101680.1| glyoxylate reductase [Herminiimonas arsenico... 459 e-127 ref|YP_297623.1| D-isomer specific 2-hydroxyacid dehydrogenase, ... 440 e-121 >ref|YP_003777690.1| D-3-phosphoglycerate dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ65782.1| D-3-phosphoglycerate dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 328 Score = 572 bits (1473), Expect = e-161, Method: Composition-based stats. Identities = 302/328 (92%), Positives = 314/328 (95%) Query: 47 MKIAILDDYQDAVRHLDCFRLLDGHDVKVFTNTVRGTGQLTARLSPFDAVVLIRERTALT 106 MKIAILDDYQDAVRHLDCFRLLDGHDVKVF NT+RG GQL ARLSPFDAVVLIRERTALT Sbjct: 1 MKIAILDDYQDAVRHLDCFRLLDGHDVKVFNNTIRGVGQLAARLSPFDAVVLIRERTALT 60 Query: 107 RPLLEKLPLLKLISQTGKVSGHVDVAAATARGIAIVEGVGDPTAPAELTWALIMAAMRRV 166 RPLLEKLPLLKL+SQTGKVSGHVDVAA T RGIAIVEGVGDPTAPAELTWALIMAAMRRV Sbjct: 61 RPLLEKLPLLKLVSQTGKVSGHVDVAACTERGIAIVEGVGDPTAPAELTWALIMAAMRRV 120 Query: 167 PQYCSALRAGAWQQVSPTPHHNLIGTALKGRTLGIWGYGKIGKLVAGYGRAFGMQVVVWG 226 PQYCSALRAGAWQQVSPTPHHNLIGTALKGRTLGIWGYGKIG+LVAGYGRAFGMQV+VWG Sbjct: 121 PQYCSALRAGAWQQVSPTPHHNLIGTALKGRTLGIWGYGKIGRLVAGYGRAFGMQVLVWG 180 Query: 227 REASREQAVKDGLQAAASKEDFFTQADVLTLHLRLNDATRGIVKASDLARMKPTACFVNT 286 R++SREQA+KDG QAAASKE+FF QADVL+LHLRLNDATRGIVKASDLARMK TACFVNT Sbjct: 181 RDSSREQAIKDGYQAAASKEEFFAQADVLSLHLRLNDATRGIVKASDLARMKATACFVNT 240 Query: 287 SRAELVEADALEAALHAGRPGLAALDVYEREPLPVDSPLLKMDNVVAAPHLGYVEKDGYE 346 SRAELVE DALEAAL AGRPGLAALDVYEREPLPV+S LL+MDNVVAAPHLGYVEKDGYE Sbjct: 241 SRAELVEPDALEAALIAGRPGLAALDVYEREPLPVESALLQMDNVVAAPHLGYVEKDGYE 300 Query: 347 LYFRAAFQNIVDYAAGTPKNVLNPEALG 374 LYFRAAFQNIV YAAG P +VLNPEALG Sbjct: 301 LYFRAAFQNIVAYAAGAPTHVLNPEALG 328 >ref|YP_001355375.1| D-isomer specific 2-hydroxyacid dehydrogenase [Janthinobacterium sp. Marseille] gb|ABR91309.1| D-isomer specific 2-hydroxyacid dehydrogenase [Janthinobacterium sp. Marseille] Length = 323 Score = 479 bits (1233), Expect = e-133, Method: Composition-based stats. Identities = 238/322 (73%), Positives = 274/322 (85%) Query: 47 MKIAILDDYQDAVRHLDCFRLLDGHDVKVFTNTVRGTGQLTARLSPFDAVVLIRERTALT 106 MKIAILDDYQD+VRHLDCF LL GH+VK+FTN RG GQL RL+ FDA+VLIRERT L+ Sbjct: 1 MKIAILDDYQDSVRHLDCFSLLAGHEVKIFTNGARGVGQLAIRLASFDALVLIRERTVLS 60 Query: 107 RPLLEKLPLLKLISQTGKVSGHVDVAAATARGIAIVEGVGDPTAPAELTWALIMAAMRRV 166 R LLEKLP LKLI+QTGKVSGH+D+ AA ARGI IVEGVGDPTAPAELTW LIMAAMR++ Sbjct: 61 RQLLEKLPNLKLIAQTGKVSGHIDLPAAAARGITIVEGVGDPTAPAELTWTLIMAAMRKL 120 Query: 167 PQYCSALRAGAWQQVSPTPHHNLIGTALKGRTLGIWGYGKIGKLVAGYGRAFGMQVVVWG 226 PQY + L+ G WQ S +P N +GTALKGRTL IWGYG+IG+++A YG+AFGM V+VWG Sbjct: 121 PQYVNNLKDGLWQIASMSPARNTLGTALKGRTLAIWGYGRIGQMIAAYGKAFGMDVMVWG 180 Query: 227 REASREQAVKDGLQAAASKEDFFTQADVLTLHLRLNDATRGIVKASDLARMKPTACFVNT 286 R AS E AV+DG +AA+S++ FF++ADVLTLHLRLNDATRGIV A DLARMKP A FVNT Sbjct: 181 RPASCEAAVRDGYRAASSQQAFFSEADVLTLHLRLNDATRGIVTADDLARMKPQALFVNT 240 Query: 287 SRAELVEADALEAALHAGRPGLAALDVYEREPLPVDSPLLKMDNVVAAPHLGYVEKDGYE 346 SRAELV DAL+AAL GRPG AALDV+E EPLP SPLL+M+NV+A+PHLGYVEKD YE Sbjct: 241 SRAELVATDALQAALEQGRPGYAALDVFENEPLPPGSPLLRMENVLASPHLGYVEKDSYE 300 Query: 347 LYFRAAFQNIVDYAAGTPKNVL 368 LYF +AFQNIVD+A GTPKNVL Sbjct: 301 LYFGSAFQNIVDFANGTPKNVL 322 >ref|YP_004755071.1| D-3-phosphoglycerate dehydrogenase [Collimonas fungivorans Ter331] gb|AEK64248.1| D-3-phosphoglycerate dehydrogenase [Collimonas fungivorans Ter331] Length = 330 Score = 466 bits (1198), Expect = e-129, Method: Composition-based stats. Identities = 238/327 (72%), Positives = 279/327 (85%) Query: 47 MKIAILDDYQDAVRHLDCFRLLDGHDVKVFTNTVRGTGQLTARLSPFDAVVLIRERTALT 106 MKIA+LDDYQD+VRHLD FRLLDGHDVKVF N+ RG GQL RL+ F+A+VLIRER++ + Sbjct: 1 MKIAVLDDYQDSVRHLDSFRLLDGHDVKVFNNSARGVGQLAIRLADFEALVLIRERSSFS 60 Query: 107 RPLLEKLPLLKLISQTGKVSGHVDVAAATARGIAIVEGVGDPTAPAELTWALIMAAMRRV 166 R LL+KLP LKLISQTGKVSGH+DV AAT GIAIVEG+GDPTAPAELTWALIMAA RR+ Sbjct: 61 RALLQKLPKLKLISQTGKVSGHIDVEAATECGIAIVEGIGDPTAPAELTWALIMAASRRI 120 Query: 167 PQYCSALRAGAWQQVSPTPHHNLIGTALKGRTLGIWGYGKIGKLVAGYGRAFGMQVVVWG 226 P+Y S L+ G WQ VS P ++++GT LKGRTL IWGYGKIG+++AGYG+AFGM+V+VWG Sbjct: 121 PRYVSNLQQGQWQSVSAIPRNDVLGTVLKGRTLAIWGYGKIGRMIAGYGKAFGMRVLVWG 180 Query: 227 REASREQAVKDGLQAAASKEDFFTQADVLTLHLRLNDATRGIVKASDLARMKPTACFVNT 286 REAS A KDG +AAASK+ FF +ADVL+LHLRLNDATRGIV+A+DLA MK +A FVNT Sbjct: 181 REASLAAAQKDGYEAAASKQQFFAEADVLSLHLRLNDATRGIVEAADLALMKSSAIFVNT 240 Query: 287 SRAELVEADALEAALHAGRPGLAALDVYEREPLPVDSPLLKMDNVVAAPHLGYVEKDGYE 346 SRAELV ALE AL GRPG AALDV+E EPL DSPLL+M+NV+A+PHLGYVEKD YE Sbjct: 241 SRAELVAEGALEPALQQGRPGFAALDVFETEPLAPDSPLLRMENVLASPHLGYVEKDSYE 300 Query: 347 LYFRAAFQNIVDYAAGTPKNVLNPEAL 373 LYFR AFQN++D+A G PKNVLNP+AL Sbjct: 301 LYFRIAFQNVLDFAGGAPKNVLNPDAL 327 >ref|YP_001101680.1| glyoxylate reductase [Herminiimonas arsenicoxydans] emb|CAL63559.1| putative Phosphoglycerate dehydrogenase [Herminiimonas arsenicoxydans] Length = 327 Score = 459 bits (1182), Expect = e-127, Method: Composition-based stats. Identities = 239/325 (73%), Positives = 277/325 (85%) Query: 47 MKIAILDDYQDAVRHLDCFRLLDGHDVKVFTNTVRGTGQLTARLSPFDAVVLIRERTALT 106 MKIAILDDYQD VR LDCF LLDGH+VKVFTN+ RG GQL RL+ FDA+VLIRERTAL+ Sbjct: 1 MKIAILDDYQDCVRQLDCFSLLDGHEVKVFTNSARGVGQLAIRLADFDALVLIRERTALS 60 Query: 107 RPLLEKLPLLKLISQTGKVSGHVDVAAATARGIAIVEGVGDPTAPAELTWALIMAAMRRV 166 RPLLEKLP LKLISQTGKVSGH+D++AA AR I IVEGVGDPTAPAELTWALIMAAMR++ Sbjct: 61 RPLLEKLPKLKLISQTGKVSGHIDLSAAAARNITIVEGVGDPTAPAELTWALIMAAMRKL 120 Query: 167 PQYCSALRAGAWQQVSPTPHHNLIGTALKGRTLGIWGYGKIGKLVAGYGRAFGMQVVVWG 226 PQY L+ G WQ S + HN +G LKGRTLGIWGYG+IG++VAGYG+AFGM+V+VWG Sbjct: 121 PQYVGNLKDGLWQIASLSSAHNTLGAVLKGRTLGIWGYGRIGRMVAGYGQAFGMKVLVWG 180 Query: 227 REASREQAVKDGLQAAASKEDFFTQADVLTLHLRLNDATRGIVKASDLARMKPTACFVNT 286 R+ASR AV+DG QAA+S+E+FF+ ADVL+LHLRLNDATRGIV ASDLA MK +A FVNT Sbjct: 181 RDASRAAAVQDGYQAASSREEFFSTADVLSLHLRLNDATRGIVTASDLAHMKSSALFVNT 240 Query: 287 SRAELVEADALEAALHAGRPGLAALDVYEREPLPVDSPLLKMDNVVAAPHLGYVEKDGYE 346 SRAELV +DAL+ AL GRPG AALDV+E EPL S LL+M+NV+A+PHLGYVEKD YE Sbjct: 241 SRAELVASDALQTALEQGRPGYAALDVFESEPLAPTSSLLRMENVLASPHLGYVEKDSYE 300 Query: 347 LYFRAAFQNIVDYAAGTPKNVLNPE 371 LYFR+AF+NIV +A G PKNVL P+ Sbjct: 301 LYFRSAFENIVAFANGAPKNVLLPK 325 >ref|YP_297623.1| D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding [Ralstonia eutropha JMP134] gb|AAZ62779.1| D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region:D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein [Ralstonia eutropha JMP134] Length = 341 Score = 440 bits (1132), Expect = e-121, Method: Composition-based stats. Identities = 221/335 (65%), Positives = 265/335 (79%), Gaps = 8/335 (2%) Query: 47 MKIAILDDYQDAVRHLDCFRLLDGHDVKVFTNTVRGTGQLTARLSPFDAVVLIRERTALT 106 MKIA+LDDYQDAVR L CF LL+GHDVKVF NTV+G GQL ARLS +AVVLIRERT +T Sbjct: 1 MKIAVLDDYQDAVRKLPCFSLLEGHDVKVFNNTVKGVGQLAARLSDVEAVVLIRERTRIT 60 Query: 107 RPLLEKLPLLKLISQTGKV----SGHVDVAAATARGIAIVEGVGDPTAPAELTWALIMAA 162 R LLEKLP LK+ISQTG+V + H+DV A T RG+A++EGVG P APAELTWALIMAA Sbjct: 61 RQLLEKLPKLKIISQTGRVGTAPNTHIDVEACTDRGVAVLEGVGSPVAPAELTWALIMAA 120 Query: 163 MRRVPQYCSALRAGAWQQV----SPTPHHNLIGTALKGRTLGIWGYGKIGKLVAGYGRAF 218 RR+PQY ++L+ GAWQQ + P + +G L+G+TLGIWGYGKIG+L+AGYGRAF Sbjct: 121 QRRIPQYVASLKHGAWQQSGLKSTTMPPNFGLGQVLRGQTLGIWGYGKIGRLLAGYGRAF 180 Query: 219 GMQVVVWGREASREQAVKDGLQAAASKEDFFTQADVLTLHLRLNDATRGIVKASDLARMK 278 GM V+VWGREAS+E A DGL A SK+ FF DVL+LHLRLND TRGIVK +DL RMK Sbjct: 181 GMNVLVWGREASQEAARADGLAVAESKDQFFADCDVLSLHLRLNDDTRGIVKLTDLTRMK 240 Query: 279 PTACFVNTSRAELVEADALEAALHAGRPGLAALDVYEREPLPVDSPLLKMDNVVAAPHLG 338 PTA FVNTSRAEL+E +AL AAL+ GRPG+AA+DV+E EP+ LL+M+N + PHLG Sbjct: 241 PTALFVNTSRAELLEENALVAALNRGRPGMAAVDVFESEPILQGHALLRMENCICTPHLG 300 Query: 339 YVEKDGYELYFRAAFQNIVDYAAGTPKNVLNPEAL 373 YVE+D YELYFR AFQNI+D AG +++NP+AL Sbjct: 301 YVERDSYELYFRTAFQNILDVLAGQHDSIVNPKAL 335