BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.5427.p (283 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777681.1| bifunctional biotin operon repressor/biotin-... 358 8e-97 ref|YP_004754850.1| biotin-protein ligase [Collimonas fungivoran... 239 4e-61 ref|YP_001354930.1| bifunctional biotin operon repressor /biotin... 224 1e-56 ref|YP_001101222.1| bifunctional biotin-[acetylCoA carboxylase] ... 219 3e-55 ref|ZP_08274265.1| Biotin-protein ligase [Oxalobacteraceae bacte... 213 2e-53 >ref|YP_003777681.1| bifunctional biotin operon repressor/biotin-[acetyl-CoA- carboxylase] synthetase [Herbaspirillum seropedicae SmR1] gb|ADJ65773.1| bifunctional: biotin operon repressor/biotin-[acetyl-CoA- carboxylase] synthetase protein [Herbaspirillum seropedicae SmR1] Length = 257 Score = 358 bits (918), Expect = 8e-97, Method: Composition-based stats. Identities = 191/261 (73%), Positives = 223/261 (85%), Gaps = 5/261 (1%) Query: 23 LIASSSNDNAKTVAVEVVAETGSTNADLLARVTAVDGARLVAPVLLVAESQTAGRGRAGR 82 L+A S + + + VE VA TGSTN DL+ RVT+ L P+LLVA+ QTAGRGRAGR Sbjct: 2 LLAGSDSQGQQRIDVEAVACTGSTNVDLMQRVTS-----LTRPLLLVADRQTAGRGRAGR 56 Query: 83 PWQTSKTSALTFSLAWKFGRPLHALIGLPLAVGVALAEALEVFGIDVELKWPNDVLRDGA 142 PW+ + +LTFSLAW+F RP+HAL+GLPLAVGVALAEALEVFG+ +LKWPNDVLR+GA Sbjct: 57 PWRAAPEDSLTFSLAWRFERPMHALLGLPLAVGVALAEALEVFGVRPQLKWPNDVLREGA 116 Query: 143 KLAGVLIETAAEGGRADATWAVIGIGLNLAVPSGLEDELQRAVGSAPELQKPPRETVLAI 202 KLAG+LIETA++G R DATWAVIGIGLNL VP GLE ELQRA+ + PEL+KPPRETVLAI Sbjct: 117 KLAGILIETASDGRRGDATWAVIGIGLNLGVPQGLEQELQRAIAAVPELRKPPRETVLAI 176 Query: 203 IASALSEVLTEFEQRGFGAFVKRWEAFHAYAGQAVKIVENGRVLQEGTAVGVDMMGRFLM 262 IASAL+EVLTEFEQRGFGAFV+RWEAFHAYAGQAVKIV+NGR+L EG AVGVDMMGRFL+ Sbjct: 177 IASALAEVLTEFEQRGFGAFVRRWEAFHAYAGQAVKIVDNGRLLHEGRAVGVDMMGRFLL 236 Query: 263 DTESGQVEILAGDVSLRLQDA 283 DTE+GQV ++ GD+SLRLQD Sbjct: 237 DTEAGQVAVMVGDLSLRLQDG 257 >ref|YP_004754850.1| biotin-protein ligase [Collimonas fungivorans Ter331] gb|AEK64027.1| Biotin-protein ligase [Collimonas fungivorans Ter331] Length = 325 Score = 239 bits (610), Expect = 4e-61, Method: Composition-based stats. Identities = 144/289 (49%), Positives = 193/289 (66%), Gaps = 12/289 (4%) Query: 1 MCAMHATETSLATTISAQRIAALIASSSNDNAKTVAVEVVAETGSTNADLLARVTA--VD 58 M A S A+ +SA RIAA + +A+ +EVVAETGSTNADLLARV+ D Sbjct: 43 MTAQFIAPISPASQLSAARIAAF----AGHHAEQCLIEVVAETGSTNADLLARVSGNGRD 98 Query: 59 GAR--LVAPVLLVAESQTAGRGRAGRPWQTSKTSALTFSLAWKFGRPLHALIGLPLAVGV 116 + L AP LLVA +QTAGRGRAGR W T+ +ALTFSLAW F PL AL+GLPLAVGV Sbjct: 99 SGKDALRAPTLLVALTQTAGRGRAGRAWLTAPAAALTFSLAWPFASPLQALVGLPLAVGV 158 Query: 117 ALAEALEVFGIDVELKWPNDVLRDGAKLAGVLIETAAEGGRADATWAVIGIGLNLAVPSG 176 +AE L FG++V+LKWPNDVL+ G KLAG+LIETA + WAVIGIG+NL++P Sbjct: 159 TIAETLADFGVEVQLKWPNDVLQGGRKLAGILIETATAPDQ--QLWAVIGIGINLSIPEK 216 Query: 177 LEDELQRAVGSAPELQKPPRETVLAIIASALSEVLTEFEQRGFGAFVKRWEAFHAYAGQA 236 L++++ R + P R+ +L + S L++ + +FE G AFV+RW HA+AGQ Sbjct: 217 LQEQIGRRTANLPAAAAQDRDLLLGSLLSGLAQNMWQFESEGLSAFVERWNRLHAFAGQQ 276 Query: 237 VKIVENGRVLQEGTAVGVDMMGRFLMDTESGQ--VEILAGDVSLRLQDA 283 V I++ G+ L EG A+G+D +GR L+ T+ G + I+AGD+SLR ++ Sbjct: 277 VAILDQGKTLHEGKALGIDQIGRLLLQTDGGSNPIAIMAGDISLRPKEG 325 >ref|YP_001354930.1| bifunctional biotin operon repressor /biotin--[acetyl-CoA-carboxylase] synthetase [Janthinobacterium sp. Marseille] gb|ABR89902.1| bifunctional biotin operon repressor /biotin--[acetyl-CoA-carboxylase] synthetase [Janthinobacterium sp. Marseille] Length = 307 Score = 224 bits (570), Expect = 1e-56, Method: Composition-based stats. Identities = 143/268 (53%), Positives = 180/268 (67%), Gaps = 10/268 (3%) Query: 16 SAQRIAALIASSSNDNAKTVAVEVVAETGSTNADLLARVTAVDGARLVAPVLLVAESQTA 75 SAQR+A L ++ A+ +A+E+VAETGSTNADLLAR L P LL A+ QTA Sbjct: 50 SAQRLAGLCTNA----AQAIALEIVAETGSTNADLLAR-----APHLQQPTLLWAQVQTA 100 Query: 76 GRGRAGRPWQTSKTSALTFSLAWKFGRPLHALIGLPLAVGVALAEALEVFGIDVELKWPN 135 G+GRAGR W T +ALTFSLAWKF PL L+GLPLAVGV +AEAL FG+D LKWPN Sbjct: 101 GKGRAGRAWHTPAGAALTFSLAWKFNLPLQGLLGLPLAVGVVIAEALRTFGVDARLKWPN 160 Query: 136 DVLRDGAKLAGVLIETAAEGGRADATWAVIGIGLNLAVPSGLEDELQRAVGSAPELQKPP 195 DVL+D KLAG+LIET A+ A+W VIG+G+N+A S L + RAV +A EL P Sbjct: 161 DVLKDDGKLAGILIETVADKSGQPASWVVIGVGINIARASDLSAQTGRAVVAATELAAEP 220 Query: 196 RETVLAIIASALSEVLTEFEQRGFGAFVKRWEAFHAYAGQAVKIVENGRVLQEGTAVGVD 255 E +A + ++ L FEQ GF FV W A AYAGQAV I++ G+VL G A GVD Sbjct: 221 -ERAMAALLDGFAQALPRFEQEGFAGFVDAWNALDAYAGQAVNILDQGQVLHSGHAAGVD 279 Query: 256 MMGRFLMDTESGQVEILAGDVSLRLQDA 283 GR L+DT G++ ++AGDVSLR+++ Sbjct: 280 AGGRLLLDTAQGRITVVAGDVSLRIREG 307 >ref|YP_001101222.1| bifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase/transcriptional repressor [Herminiimonas arsenicoxydans] emb|CAL63101.1| Putative bifunctional protein birA [Includes: Biotin operon repressor; Biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase)] [Herminiimonas arsenicoxydans] Length = 263 Score = 219 bits (559), Expect = 3e-55, Method: Composition-based stats. Identities = 128/259 (49%), Positives = 168/259 (64%), Gaps = 8/259 (3%) Query: 24 IASSSNDNAKTVAVEVVAETGSTNADLLARVTAVDGARLVAPVLLVAESQTAGRGRAGRP 83 +A+ + + + +V ETGSTNADLLA T + G P LL A QTAG+GRAGR Sbjct: 12 LAALCGSEVQNMTLRIVTETGSTNADLLAETTQLQG-----PTLLWAGVQTAGKGRAGRR 66 Query: 84 WQTSKTSALTFSLAWKFGRPLHALIGLPLAVGVALAEALEVFGIDVELKWPNDVLRDGAK 143 W ++ + LTFSLAWKF P+ AL GL LAVGV + E L FG+D +LKWPNDVLR+G K Sbjct: 67 WHSAADATLTFSLAWKFALPVQALAGLSLAVGVTVVETLISFGVDAQLKWPNDVLRNGNK 126 Query: 144 LAGVLIETAAEGGRADATWAVIGIGLNLAVPSGLEDELQRAVGSAPELQKPPRETVLAII 203 LAG+LIETA + + WA+IG+G+NLA L ++ R V A L+ R ++A + Sbjct: 127 LAGILIETAMDKTDRQSIWAIIGVGINLADARNLSAQIGRTVADASGLE---RVRLMAAL 183 Query: 204 ASALSEVLTEFEQRGFGAFVKRWEAFHAYAGQAVKIVENGRVLQEGTAVGVDMMGRFLMD 263 A S+ L FEQ+GF AF W A AYAGQAV I++ ++LQ G A GVD GR L+D Sbjct: 184 LDAFSKALPLFEQQGFKAFAPAWNALDAYAGQAVNILDQEKILQHGDAAGVDEAGRLLLD 243 Query: 264 TESGQVEILAGDVSLRLQD 282 T G++ I AGDVSLR+++ Sbjct: 244 TAQGRIAISAGDVSLRIRE 262 >ref|ZP_08274265.1| Biotin-protein ligase [Oxalobacteraceae bacterium IMCC9480] gb|EGF32274.1| Biotin-protein ligase [Oxalobacteraceae bacterium IMCC9480] Length = 264 Score = 213 bits (543), Expect = 2e-53, Method: Composition-based stats. Identities = 131/258 (50%), Positives = 169/258 (65%), Gaps = 5/258 (1%) Query: 22 ALIASSSNDNAKTVAVEVVAETGSTNADLLARVTAVDGARLVAPVLLVAESQTAGRGRAG 81 A IA++ + +E VAETGSTNADLLAR+ + G PV LVA+ QTAGRGRAG Sbjct: 8 ARIAAALRTAVPGLTIEAVAETGSTNADLLARLDQLHG-----PVFLVADQQTAGRGRAG 62 Query: 82 RPWQTSKTSALTFSLAWKFGRPLHALIGLPLAVGVALAEALEVFGIDVELKWPNDVLRDG 141 R W + + ++LTFSLAW PL AL+GLPLAVGVALA+ L GI V+LKWPND+L DG Sbjct: 63 RTWHSERGASLTFSLAWPVRVPLQALVGLPLAVGVALADVLAGHGIAVQLKWPNDLLADG 122 Query: 142 AKLAGVLIETAAEGGRADATWAVIGIGLNLAVPSGLEDELQRAVGSAPELQKPPRETVLA 201 +KLAG+LIETA + WAVIGIG+NL + L + + V + P+ R+ +LA Sbjct: 123 SKLAGILIETAVDRQAGARLWAVIGIGINLTDNAALAARIGQPVAALPDAGAIDRDLLLA 182 Query: 202 IIASALSEVLTEFEQRGFGAFVKRWEAFHAYAGQAVKIVENGRVLQEGTAVGVDMMGRFL 261 + L L EFE+ GF F +RW A H + GQ V I++ G+ + EG AVGVD GR L Sbjct: 183 DLLGHLCLTLQEFEEYGFAVFAERWNALHTHRGQPVSIIDRGQTVCEGVAVGVDAQGRLL 242 Query: 262 MDTESGQVEILAGDVSLR 279 +DT G+ ++AGDVSLR Sbjct: 243 LDTAQGRRTVVAGDVSLR 260