BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.5266.p (512 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777510.1| 3-hydroxyacyl-CoA dehydrogenase [Herbaspiril... 724 0.0 ref|YP_283601.1| 3-hydroxybutyryl-CoA dehydrogenase [Dechloromon... 526 e-147 ref|ZP_02376706.1| 3-hydroxybutyryl-CoA dehydrogenase [Burkholde... 496 e-138 ref|ZP_04947471.1| 3-hydroxyacyl-CoA dehydrogenase [Burkholderia... 494 e-137 ref|ZP_04941604.1| 3-hydroxybutyryl-CoA dehydrogenase [Burkholde... 493 e-137 >ref|YP_003777510.1| 3-hydroxyacyl-CoA dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ65602.1| 3-hydroxyacyl-CoA dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 512 Score = 724 bits (1869), Expect = 0.0, Method: Composition-based stats. Identities = 371/512 (72%), Positives = 424/512 (82%) Query: 1 MSAAESPHALPATARVAVIGSGTMGAGIAQVAAVAGHPVQLYDSRDGAAAKAIADIRASL 60 M+ + PHAL +A VAVIGSGTMGAGIAQVAAVAGHPV LYDSR+GAA KAI I +L Sbjct: 1 MNNRKYPHALSRSALVAVIGSGTMGAGIAQVAAVAGHPVLLYDSREGAAGKAIGAICTNL 60 Query: 61 DKLANKGKITHEQAQGASDRLSVAHALQEMRDARLVVEAIVEQLAAKQELFGKLEAIVDA 120 DKL +K K+T AQ AS R+SVA +L+E+ A LV+EAIVEQLAAK ELFGKLEAIV Sbjct: 61 DKLVSKDKLTPALAQAASQRISVAQSLEELHQADLVIEAIVEQLAAKHELFGKLEAIVST 120 Query: 121 QCILASNTSSISITQIAATLRHPERLAGMHFFNPVPMMALVEIIRGVCSDATVVQCLHDT 180 +CILA+NTSS+SITQIAA L+HPER+ GMHFFNPVPMMALVEII G+ SDA + QCLHDT Sbjct: 121 RCILATNTSSLSITQIAAGLQHPERVVGMHFFNPVPMMALVEIISGLASDAALAQCLHDT 180 Query: 181 ALAWGKVPVVAASTPGFIVNRLARPYYAEALRVLNERGAQPATIDAILRESGGFRMGAFE 240 ALAWGK PV+A STPGFIVNRLARPYYAE LR+L+E GAQPATIDA++RE+GGFRMG FE Sbjct: 181 ALAWGKTPVMARSTPGFIVNRLARPYYAEGLRMLHEGGAQPATIDAVMREAGGFRMGPFE 240 Query: 241 LMDLIGHDVNFAVTQSVFQAYFNDPRFTPSLIQQELVHAGFLGRKSGRGFYRYGEAPETP 300 LMDLIGHDVNFAVTQSVF AYFNDPRFTPSLIQQELVHAG+LGRKSGRGFYRYGEA P Sbjct: 241 LMDLIGHDVNFAVTQSVFHAYFNDPRFTPSLIQQELVHAGYLGRKSGRGFYRYGEAAGAP 300 Query: 301 QPVTVPAFDTPTVPLQLFGTHPLVEVIRARYQGRVEYCEARADHLLMKAGPGRLYMTGGR 360 +P T + PT QL+G HPLVE+I RY G+V+ AR D LLMK L +T GR Sbjct: 301 RPETERDYPKPTATPQLYGDHPLVEMIHTRYPGQVQRHPARPDQLLMKVNAACLCITDGR 360 Query: 361 SATQQSYDYNMPDVVLVDLALDYATAPRLALTRADQCRDRAWEAVAGVLQHCGFALSPLQ 420 SAT +++++ PD+VLVDLALDYA A RLAL +ADQCR + + VAGVLQ CG LSP+Q Sbjct: 361 SATLRAWEHQEPDLVLVDLALDYADATRLALAKADQCRPQRYAEVAGVLQACGLDLSPMQ 420 Query: 421 DVPGMVVMRTVCMLINEAADAVSQGVCSKQDADLAMQKGVNYPRGPLAWADAIGVDTVAN 480 DVPGM+VMRTVCML+NEAADAV+QGVC+ DAD+AM+KGVNYPRGPLAWA+ IG+DTV Sbjct: 421 DVPGMMVMRTVCMLVNEAADAVNQGVCNAADADMAMRKGVNYPRGPLAWANEIGIDTVNQ 480 Query: 481 VLRQLSATYGEDRYRVAPLLQRLQASGRKFHE 512 VL L ATYGEDRYR++PLLQRL ASGRKFHE Sbjct: 481 VLHHLCATYGEDRYRISPLLQRLYASGRKFHE 512 >ref|YP_283601.1| 3-hydroxybutyryl-CoA dehydrogenase [Dechloromonas aromatica RCB] gb|AAZ45131.1| 3-hydroxyacyl-CoA dehydrogenase [Dechloromonas aromatica RCB] Length = 519 Score = 526 bits (1356), Expect = e-147, Method: Composition-based stats. Identities = 300/505 (59%), Positives = 365/505 (72%), Gaps = 3/505 (0%) Query: 10 LPATARVAVIGSGTMGAGIAQVAAVAGHPVQLYDSRDGAAAKAIADIRASLDKLANKGKI 69 LP A +AV+G+G MGAGIAQVAA AGHPV+L D+R GAA KA+A IRA KLA KGK+ Sbjct: 16 LPQQAVIAVVGTGAMGAGIAQVAAAAGHPVKLLDNRPGAADKAVAGIRAQFAKLAEKGKL 75 Query: 70 THEQAQGASDRLSVAHALQEMRDARLVVEAIVEQLAAKQELFGKLEAIVDAQCILASNTS 129 T E AQ A +RLS L ++ DA LVVEAIVE L AKQ+L+ LEAIV A CI +NTS Sbjct: 76 TTEAAQAAGERLSAVEQLADLADAALVVEAIVENLDAKQKLYADLEAIVGADCIFGTNTS 135 Query: 130 SISITQIAATLRHPERLAGMHFFNPVPMMALVEIIRGVCSDATVVQCLHDTALAWGKVPV 189 SIS+T I A L+HPERLAG+HFFNP P+MALVEI+ G+ +D V L TA AWGK V Sbjct: 136 SISVTAIGAALKHPERLAGLHFFNPAPLMALVEIVSGLATDKAVADTLFSTANAWGKTAV 195 Query: 190 VAASTPGFIVNRLARPYYAEALRVLNERGAQPATIDAILRESGGFRMGAFELMDLIGHDV 249 A STPGFIVNR+ARPYYAEALRV E A ATIDA RE+GGFRMG FELMD+IGHDV Sbjct: 196 HAKSTPGFIVNRVARPYYAEALRVAQEGAADYATIDACCREAGGFRMGPFELMDMIGHDV 255 Query: 250 NFAVTQSVFQAYFNDPRFTPSLIQQELVHAGFLGRKSGRGFYRYGEAPETPQPVTVPAFD 309 NFAVT SV++A++ND RF PSLIQQELV AGF GRKSGRGFY Y E P+P T A Sbjct: 256 NFAVTNSVWRAFYNDQRFLPSLIQQELVDAGFYGRKSGRGFYDYREGAVKPEPQTEAA-Q 314 Query: 310 TPTVPLQLFGTHPLVEVIRARYQ-GRVEYCEA-RADHLLMKAGPGRLYMTGGRSATQQSY 367 TP + +FG L E++ R Q + Y A +D + + G +LY+T GRSATQ++ Sbjct: 315 TPAGKITVFGESDLAELLVERLQHSALSYNRAPDSDGRIAEIGFAKLYVTDGRSATQRAA 374 Query: 368 DYNMPDVVLVDLALDYATAPRLALTRADQCRDRAWEAVAGVLQHCGFALSPLQDVPGMVV 427 + + + VL+DLALDY+ A RLA+ A+QC A + G+LQ GFA+S DVPG++V Sbjct: 375 ETGVANTVLIDLALDYSKATRLAIAAAEQCEPAAVASAVGLLQATGFAVSRFLDVPGLIV 434 Query: 428 MRTVCMLINEAADAVSQGVCSKQDADLAMQKGVNYPRGPLAWADAIGVDTVANVLRQLSA 487 MRTV ML NEAADAV+QGVCS+ AD AM+ GVNYP+GPLAWAD +GV + +VL L A Sbjct: 435 MRTVAMLANEAADAVNQGVCSEAGADQAMRLGVNYPQGPLAWADQVGVAAIRDVLANLGA 494 Query: 488 TYGEDRYRVAPLLQRLQASGRKFHE 512 +YGEDRYR++PL+QR +GR H+ Sbjct: 495 SYGEDRYRISPLIQRAVFAGRNIHD 519 >ref|ZP_02376706.1| 3-hydroxybutyryl-CoA dehydrogenase [Burkholderia ubonensis Bu] Length = 518 Score = 496 bits (1278), Expect = e-138, Method: Composition-based stats. Identities = 299/496 (60%), Positives = 359/496 (72%), Gaps = 4/496 (0%) Query: 6 SPHALPATARVAVIGSGTMGAGIAQVAAVAGHPVQLYDSRDGAAAKAIADIRASLDKLAN 65 +P AL A V VIG+G MGAGIAQVAA AGHPV LYD + A KA+A IRA +LA Sbjct: 10 NPGALAPAAVVGVIGAGAMGAGIAQVAAAAGHPVLLYDLNEAACDKALAGIRAQFARLAE 69 Query: 66 KGKITHEQAQGASDRLSVAHALQEMRDARLVVEAIVEQLAAKQELFGKLEAIVDAQCILA 125 KG++ QAQ A++R+S AL + A LVVEA E+L K+E+F LE VD C+LA Sbjct: 70 KGRLDPAQAQAAANRVSAVRALADFAPAALVVEAAAERLDVKREIFATLERHVDDACLLA 129 Query: 126 SNTSSISITQIAATLRHPERLAGMHFFNPVPMMALVEIIRGVCSDATVVQCLHDTALAWG 185 +NTSSISIT IAA LR P+R+AG+HFFNP P+MALVE++ G+ + V Q L+DTA AWG Sbjct: 130 TNTSSISITAIAAGLRAPQRVAGLHFFNPAPLMALVEVVSGLATAPEVAQVLYDTAAAWG 189 Query: 186 KVPVVAASTPGFIVNRLARPYYAEALRVLNERGAQPATIDAILRESGGFRMGAFELMDLI 245 K PV+A STPGFIVNR+ARPYYAEALRVLNE+G PA+IDA++RE+GGFRMG FELMDLI Sbjct: 190 KRPVLAKSTPGFIVNRVARPYYAEALRVLNEQGGAPASIDAVMREAGGFRMGPFELMDLI 249 Query: 246 GHDVNFAVTQSVFQAYFNDPRFTPSLIQQELVHAGFLGRKSGRGFYRYGEAPETPQPVTV 305 GHDVNFAVT+SVF+AYFNDPRFTPSLIQQELV+AGFLGRKSGRGFY Y + P P Sbjct: 250 GHDVNFAVTESVFRAYFNDPRFTPSLIQQELVNAGFLGRKSGRGFYSYADGATPPAPDVE 309 Query: 306 PAFDTPTVPLQLFGTHPLVEVIRARYQGRV---EYCEARADHLLMKAGPGRLYMTGGRSA 362 P D P + LF + +R R RV + +A D LL AG + +T GR+A Sbjct: 310 PPCDAPAA-VTLFAQDGPADALRVRVAERVAGARHADAHPDDLLATAGRASIALTDGRTA 368 Query: 363 TQQSYDYNMPDVVLVDLALDYATAPRLALTRADQCRDRAWEAVAGVLQHCGFALSPLQDV 422 T+++ + D+VLVDLA DYA A +ALTRA QC D A+ G+ Q GF + L DV Sbjct: 369 TERAAQTGVADLVLVDLARDYAQAGLVALTRALQCSDAAYADAVGLFQQAGFRVVGLADV 428 Query: 423 PGMVVMRTVCMLINEAADAVSQGVCSKQDADLAMQKGVNYPRGPLAWADAIGVDTVANVL 482 PGM+VMRTV ML NEAAD V+QGVCS D DLAM+KGVNYP GPLAWADAIG+ V VL Sbjct: 429 PGMIVMRTVAMLANEAADTVNQGVCSPADLDLAMEKGVNYPSGPLAWADAIGIARVHRVL 488 Query: 483 RQLSATYGEDRYRVAP 498 L+A+YGEDRYRV+P Sbjct: 489 SHLAASYGEDRYRVSP 504 >ref|ZP_04947471.1| 3-hydroxyacyl-CoA dehydrogenase [Burkholderia dolosa AUO158] gb|EAY70642.1| 3-hydroxyacyl-CoA dehydrogenase [Burkholderia dolosa AUO158] Length = 518 Score = 494 bits (1272), Expect = e-137, Method: Composition-based stats. Identities = 295/505 (58%), Positives = 360/505 (71%), Gaps = 4/505 (0%) Query: 9 ALPATARVAVIGSGTMGAGIAQVAAVAGHPVQLYDSRDGAAAKAIADIRASLDKLANKGK 68 ALPA+A V VIG+G MGAGIAQVAA AGH V LYD + A A+A IRA +LA+KG+ Sbjct: 13 ALPASAVVGVIGAGAMGAGIAQVAAAAGHTVLLYDLSEAACDNALAGIRAQFARLADKGR 72 Query: 69 ITHEQAQGASDRLSVAHALQEMRDARLVVEAIVEQLAAKQELFGKLEAIVDAQCILASNT 128 + QA A++R+ AL + DA L+VEA E+L K+E+F LE V C+LA+NT Sbjct: 73 LEPAQADAAANRIRAVRALADCADAALIVEAAAERLDVKREIFATLERHVGDACVLATNT 132 Query: 129 SSISITQIAATLRHPERLAGMHFFNPVPMMALVEIIRGVCSDATVVQCLHDTALAWGKVP 188 SSISIT IAA LR PER+AG+HFFNP P+MALVE++ G+ + V Q L+ TA+AWGK P Sbjct: 133 SSISITSIAAGLRAPERVAGLHFFNPAPLMALVEVVSGLATAPAVAQMLYATAVAWGKRP 192 Query: 189 VVAASTPGFIVNRLARPYYAEALRVLNERGAQPATIDAILRESGGFRMGAFELMDLIGHD 248 V+ STPGFIVNR+ARPYYAEALR LNE+G PA+IDA++RE+GGFRMG FELMDLIGHD Sbjct: 193 VMVKSTPGFIVNRVARPYYAEALRALNEQGGTPASIDAVMREAGGFRMGPFELMDLIGHD 252 Query: 249 VNFAVTQSVFQAYFNDPRFTPSLIQQELVHAGFLGRKSGRGFYRYGEAPETPQPVTVPAF 308 VNFAVT+SVF+AYFNDPR+TPSLIQQELV+AGFLGRKSGRGFY Y + P P P Sbjct: 253 VNFAVTESVFRAYFNDPRYTPSLIQQELVNAGFLGRKSGRGFYSYADDATPPAPDVEPPC 312 Query: 309 DTPTVPLQLFGTHPLVEVIRARYQGRV---EYCEARADHLLMKAGPGRLYMTGGRSATQQ 365 D P + LF + AR R+ + +A D LL AG + +T GR+AT + Sbjct: 313 DAPA-DVVLFAQDGPAAALHARLAQRIAGARHADAHRDDLLASAGRASIALTDGRTATVR 371 Query: 366 SYDYNMPDVVLVDLALDYATAPRLALTRADQCRDRAWEAVAGVLQHCGFALSPLQDVPGM 425 + +PD+VLVDLA DYA A +ALTRA QC D A+ G+ Q GF + + DVPGM Sbjct: 372 AQQTGVPDLVLVDLARDYAQAGLVALTRALQCSDAAYADAVGLFQQAGFRVVRIGDVPGM 431 Query: 426 VVMRTVCMLINEAADAVSQGVCSKQDADLAMQKGVNYPRGPLAWADAIGVDTVANVLRQL 485 + MRTV ML NEAAD V+QGVCS D DLAM+KGVNYP GPLAWADAIG+ V VL L Sbjct: 432 IAMRTVAMLANEAADTVNQGVCSPADLDLAMEKGVNYPCGPLAWADAIGIGRVHRVLSNL 491 Query: 486 SATYGEDRYRVAPLLQRLQASGRKF 510 +A+YGEDRYRV+P + L A+GR F Sbjct: 492 AASYGEDRYRVSPRIVALHAAGRTF 516 >ref|ZP_04941604.1| 3-hydroxybutyryl-CoA dehydrogenase [Burkholderia cenocepacia PC184] gb|EAY64775.1| 3-hydroxybutyryl-CoA dehydrogenase [Burkholderia cenocepacia PC184] Length = 518 Score = 493 bits (1270), Expect = e-137, Method: Composition-based stats. Identities = 298/505 (59%), Positives = 355/505 (70%), Gaps = 4/505 (0%) Query: 9 ALPATARVAVIGSGTMGAGIAQVAAVAGHPVQLYDSRDGAAAKAIADIRASLDKLANKGK 68 AL +A V VIG+G MGAGIAQVAA AGH V LYD + A KA+A IRA +LA KG+ Sbjct: 13 ALAPSAVVGVIGAGAMGAGIAQVAAAAGHAVLLYDLNEAACDKALAGIRAQFARLAEKGR 72 Query: 69 ITHEQAQGASDRLSVAHALQEMRDARLVVEAIVEQLAAKQELFGKLEAIVDAQCILASNT 128 + QA A +RL AL + A L+VEA E+L K+E+F LE VD C+LA+NT Sbjct: 73 LEPAQADAAGNRLRAVRALADFAGAALIVEAAAERLDVKREIFATLERHVDDACVLATNT 132 Query: 129 SSISITQIAATLRHPERLAGMHFFNPVPMMALVEIIRGVCSDATVVQCLHDTALAWGKVP 188 SSISIT IAA LR P+R+AG+HFFNP P+MALVE++ G+ + V LH TA AWGK P Sbjct: 133 SSISITSIAAGLRVPQRVAGLHFFNPAPLMALVEVVSGLATAPEVAGMLHATAAAWGKQP 192 Query: 189 VVAASTPGFIVNRLARPYYAEALRVLNERGAQPATIDAILRESGGFRMGAFELMDLIGHD 248 V+A STPGFIVNR+ARPYYAEALRVLNE+G PATIDA++RE+GGFRMG FELMDLIGHD Sbjct: 193 VMAKSTPGFIVNRVARPYYAEALRVLNEQGGTPATIDAVMREAGGFRMGPFELMDLIGHD 252 Query: 249 VNFAVTQSVFQAYFNDPRFTPSLIQQELVHAGFLGRKSGRGFYRYGEAPETPQPVTVPAF 308 VNFAVT+SVF+AYFNDPR+TPSLIQQELV+AGFLGRKSGRGFY Y + P P P Sbjct: 253 VNFAVTESVFRAYFNDPRYTPSLIQQELVNAGFLGRKSGRGFYSYADGATPPAPDLEPPR 312 Query: 309 DTPTVPLQLFGTHPLVEVIRARYQGRVEYCE---ARADHLLMKAGPGRLYMTGGRSATQQ 365 P + LF + AR R+E A AD LL AG + +T GR+AT + Sbjct: 313 AAPA-EIALFAQDGPAAALHARLAERIEGARRNGAHADELLAVAGRASIALTDGRTATAR 371 Query: 366 SYDYNMPDVVLVDLALDYATAPRLALTRADQCRDRAWEAVAGVLQHCGFALSPLQDVPGM 425 + + D+VLVDLA DYA A +ALTRA QC D A+ G+ Q GF + + DVPGM Sbjct: 372 AAQTGVADLVLVDLARDYAQAGLVALTRALQCNDAAYADAVGLFQQAGFRVVGIADVPGM 431 Query: 426 VVMRTVCMLINEAADAVSQGVCSKQDADLAMQKGVNYPRGPLAWADAIGVDTVANVLRQL 485 V MRTV ML NEAAD V+QGVCS D DLAM+KGVNYP GPLAWADAIG+ V VL L Sbjct: 432 VAMRTVAMLANEAADTVNQGVCSPADLDLAMEKGVNYPCGPLAWADAIGIGRVHRVLSNL 491 Query: 486 SATYGEDRYRVAPLLQRLQASGRKF 510 +A+YGEDRYRV+P + L A+GR F Sbjct: 492 AASYGEDRYRVSPRVAALHAAGRTF 516