BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.4959.p (532 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777207.1| long-chain-fatty-acid-CoA ligase [Herbaspiri... 1065 0.0 ref|YP_003911146.1| AMP-dependent synthetase and ligase [Burkhol... 737 0.0 ref|YP_001791401.1| acyl-CoA synthetase [Leptothrix cholodnii SP... 659 0.0 ref|XP_002945010.1| PREDICTED: tyrocidine synthase 2-like [Xenop... 654 0.0 ref|YP_001861065.1| AMP-dependent synthetase and ligase [Burkhol... 644 0.0 >ref|YP_003777207.1| long-chain-fatty-acid-CoA ligase [Herbaspirillum seropedicae SmR1] gb|ADJ65299.1| long-chain-fatty-acid-CoA ligase protein [Herbaspirillum seropedicae SmR1] Length = 556 Score = 1065 bits (2754), Expect = 0.0, Method: Composition-based stats. Identities = 510/532 (95%), Positives = 522/532 (98%) Query: 1 MLSKVMNLGRLLSDVARRFPEEPGLILAQGATDGSDRLIPWREINARVDALAHALTRRGV 60 MLSKVMNLGRLLSDVARRFP+EPGLILAQGA DGSDRLIPWREINARVDALAHALTRRGV Sbjct: 25 MLSKVMNLGRLLSDVARRFPDEPGLILAQGAADGSDRLIPWREINARVDALAHALTRRGV 84 Query: 61 KKGDKMLVHSRNNQQIFESAWAAFKMGVVWVPTNFRITPPEAAYLGQSSEACVMLYDRGF 120 KKGDKMLVHSRNNQQIFESAWAAFKMGVVWVPTNFRITPPEAAYLGQSS ACVMLYDRGF Sbjct: 85 KKGDKMLVHSRNNQQIFESAWAAFKMGVVWVPTNFRITPPEAAYLGQSSGACVMLYDRGF 144 Query: 121 APYVDAVKSASPALEHVVALADARPGELDYETLVADGSGDTFREAEVDYDDPLWFFYTSG 180 A YVDAVK+ASPALEHVVALADAR GELDYE LV +GSG FREAEVDYDDPLWFFYTSG Sbjct: 145 AQYVDAVKAASPALEHVVALADARAGELDYEALVREGSGAAFREAEVDYDDPLWFFYTSG 204 Query: 181 TTGHPKAGMLSHGQMAFVVTNHLADLMPGLTHQSRSLVVAPLSHGAGVHAVVNTARGAAS 240 TTGHPKAGMLSHGQMAFVVTNHLADLMPGLTHQSRSLVVAPLSHGAGVHAV+NTARGAAS Sbjct: 205 TTGHPKAGMLSHGQMAFVVTNHLADLMPGLTHQSRSLVVAPLSHGAGVHAVINTARGAAS 264 Query: 241 ILLSSERLVVEEAWQLVEKYKVDNLFTVPTIVKILVEDESVDRYDHSSLKHVIYAGAPMY 300 ILLSSERLVVEEAWQLVEKY+VDNLFTVPTIVKILVEDESVDRYDHSSLKHVIYAGAPMY Sbjct: 265 ILLSSERLVVEEAWQLVEKYRVDNLFTVPTIVKILVEDESVDRYDHSSLKHVIYAGAPMY 324 Query: 301 RADQVHALKKLGKVLVQYYGLGEVTGNITFLPPYLHFEDDAHPQARVGTCGMPRTGMQVA 360 RADQV+ALKKLGKVLVQYYGLGEVTGNITFLPPYLHFEDDAHPQARVGTCGMPRTGMQ+A Sbjct: 325 RADQVYALKKLGKVLVQYYGLGEVTGNITFLPPYLHFEDDAHPQARVGTCGMPRTGMQIA 384 Query: 361 ILNEDGQELAPFETGEICVRGPAVFMGYHNNPEANAKAFKHDWFHTGDLGHVDKDGFLYI 420 ILN+DGQELAPFETGEICVRGPAVFMGYHNNPEANAKAFKHDWFHTGDLGHVD+DGFLYI Sbjct: 385 ILNDDGQELAPFETGEICVRGPAVFMGYHNNPEANAKAFKHDWFHTGDLGHVDQDGFLYI 444 Query: 421 TGRSSDMYISGGSNVYPREIEEALLTHPAVSEVAVLGVPDPKWGESGLAVIVCKAGQHAD 480 TGRSSDMYISGGSNVYPREIEEALLTHPAVSEVAVLGVPDPKWGESGLAVIVCKAGQ D Sbjct: 445 TGRSSDMYISGGSNVYPREIEEALLTHPAVSEVAVLGVPDPKWGESGLAVIVCKAGQQVD 504 Query: 481 GEALLAHLETRIGKYKWPRRFVYWDSMPKSGYGKIVKKQIKALLEEQGDYRL 532 GEALLAHLE+RIGKYKWPRRF+YWDSMPKSGYGKIVKKQIKALLEEQG+YRL Sbjct: 505 GEALLAHLESRIGKYKWPRRFIYWDSMPKSGYGKIVKKQIKALLEEQGEYRL 556 >ref|YP_003911146.1| AMP-dependent synthetase and ligase [Burkholderia sp. CCGE1003] gb|ADN61855.1| AMP-dependent synthetase and ligase [Burkholderia sp. CCGE1003] Length = 525 Score = 737 bits (1903), Expect = 0.0, Method: Composition-based stats. Identities = 358/524 (68%), Positives = 426/524 (81%), Gaps = 7/524 (1%) Query: 1 MLSKVMNLGRLLSDVARRFPEEPGLILAQGATDGSDRLIPWREINARVDALAHALTRRGV 60 ML+ VMNLG LL+D ARR ++PG I A R + W+EIN RVD++AH L+R GV Sbjct: 1 MLTTVMNLGNLLTDAARRHADQPGFIHA-------GRSMSWQEINTRVDSVAHGLSRLGV 53 Query: 61 KKGDKMLVHSRNNQQIFESAWAAFKMGVVWVPTNFRITPPEAAYLGQSSEACVMLYDRGF 120 KGD++LVHSRNN +FESAW AFK+G VWVPTN RIT EAAYLG+SS A VM+Y+ GF Sbjct: 54 GKGDRILVHSRNNIALFESAWVAFKLGAVWVPTNCRITATEAAYLGESSGAKVMIYEAGF 113 Query: 121 APYVDAVKSASPALEHVVALADARPGELDYETLVADGSGDTFREAEVDYDDPLWFFYTSG 180 +VDAV++AS AL+HVVA+ AR GEL+YE L F A+VD DDPLWFFYTSG Sbjct: 114 DAHVDAVRAASAALKHVVAIGKARVGELEYEVLARQMIAPPFAAADVDRDDPLWFFYTSG 173 Query: 181 TTGHPKAGMLSHGQMAFVVTNHLADLMPGLTHQSRSLVVAPLSHGAGVHAVVNTARGAAS 240 TTG PKAG+L+HGQMAFV+TNH+ADLMPGLTH+SRSLVVAPLSHGAG+HA+VN AR AAS Sbjct: 174 TTGRPKAGVLTHGQMAFVLTNHIADLMPGLTHESRSLVVAPLSHGAGIHAMVNVARAAAS 233 Query: 241 ILLSSERLVVEEAWQLVEKYKVDNLFTVPTIVKILVEDESVDRYDHSSLKHVIYAGAPMY 300 +L +SE+L EEAW LVE+Y+VDN+FTVPTIVK+L E ESV RYDHSSLK+VIYAGAPMY Sbjct: 234 VLPASEKLDAEEAWALVERYRVDNMFTVPTIVKMLTEHESVSRYDHSSLKYVIYAGAPMY 293 Query: 301 RADQVHALKKLGKVLVQYYGLGEVTGNITFLPPYLHFEDDAHPQARVGTCGMPRTGMQVA 360 R DQ HAL+ LG VLVQYYGLGEVTGNIT LP LH DD ARVGTCG RTGM++ Sbjct: 294 REDQKHALRTLGNVLVQYYGLGEVTGNITVLPASLHRADDDSADARVGTCGYARTGMEIG 353 Query: 361 ILNEDGQELAPFETGEICVRGPAVFMGYHNNPEANAKAFKHDWFHTGDLGHVDKDGFLYI 420 IL+++G L+ +GEICVRGPAVF+GY+NNPEANAKAFK+ WFHTGDLGH+D++GFLYI Sbjct: 354 ILDDEGHRLSAGASGEICVRGPAVFIGYYNNPEANAKAFKYGWFHTGDLGHLDEEGFLYI 413 Query: 421 TGRSSDMYISGGSNVYPREIEEALLTHPAVSEVAVLGVPDPKWGESGLAVIVCKAGQHAD 480 TGR+SDMYISGGSNVYPRE+EEA+LTH AV EVAV+G+PD KWGE G+AV+V + G + Sbjct: 414 TGRASDMYISGGSNVYPREVEEAILTHKAVQEVAVVGMPDAKWGEIGVAVVVLREGWALE 473 Query: 481 GEALLAHLETRIGKYKWPRRFVYWDSMPKSGYGKIVKKQIKALL 524 EALLAHLE + +YKWP+R V+WD++PKS YGKIVKK IK +L Sbjct: 474 EEALLAHLEPYLARYKWPKRCVFWDALPKSAYGKIVKKDIKLML 517 >ref|YP_001791401.1| acyl-CoA synthetase [Leptothrix cholodnii SP-6] gb|ACB34636.1| AMP-dependent synthetase and ligase [Leptothrix cholodnii SP-6] Length = 532 Score = 659 bits (1700), Expect = 0.0, Method: Composition-based stats. Identities = 328/529 (62%), Positives = 401/529 (75%), Gaps = 9/529 (1%) Query: 3 SKVMNLGRLLSDVARRFPEEPGLILAQGATDGSDRLIPWREINARVDALAHALTRRGVKK 62 ++ NL +LL AR+FP+ PGLI QG D W +I+ RVDAL AL G++K Sbjct: 4 AQACNLAQLLRQTARQFPDRPGLI--QG-----DNRWSWSQIDRRVDALVAALHALGLQK 56 Query: 63 GDKMLVHSRNNQQIFESAWAAFKMGVVWVPTNFRITPPEAAYLGQSSEACVMLYDRGFAP 122 GD +L SRNN +FE AWAAF+MG VWVPTNFR+TP E AYLG+SS A ML + FA Sbjct: 57 GDCILTQSRNNLAMFECAWAAFRMGCVWVPTNFRLTPQEVAYLGESSGARAMLVETCFAG 116 Query: 123 YVDAVKSASPALEHVVAL-ADARPGELDYETLVADGSGDTFREAEVDYDDPLWFFYTSGT 181 + +AV++A+P L+HVV + ADA G LDYE L+A + EA V +DDPLWFFYTSGT Sbjct: 117 HAEAVQAAAPELKHVVWIGADAPAGSLDYEALLARHADAPAAEATVAHDDPLWFFYTSGT 176 Query: 182 TGHPKAGMLSHGQMAFVVTNHLADLMPGLTHQSRSLVVAPLSHGAGVHAVVNTARGAASI 241 TG PKA +L+HGQM FVVTNHLADL+PG T S+ VAPLSHGAG+HA++N ARGAA++ Sbjct: 177 TGKPKAAILTHGQMGFVVTNHLADLIPGTTETDCSIAVAPLSHGAGIHALLNVARGAATV 236 Query: 242 LLSSERLVVEEAWQLVEKYKVDNLFTVPTIVKILVEDESVDRYDHSSLKHVIYAGAPMYR 301 LL E++ WQL+ +++V NLFTVPTIVK+LVE +VD+ DHSSL+HVIYAGAPMYR Sbjct: 237 LLPGEKMDPAVVWQLIAQHRVSNLFTVPTIVKLLVEHPAVDQCDHSSLRHVIYAGAPMYR 296 Query: 302 ADQVHALKKLGKVLVQYYGLGEVTGNITFLPPYLHFEDDAHPQARVGTCGMPRTGMQVAI 361 ADQ AL+KLG VLVQY+GLGEVTG IT LP ++H DDA P A +G+CG PRTGM+VA+ Sbjct: 297 ADQRLALQKLGPVLVQYFGLGEVTGCITVLPAHMHSADDADPNAHIGSCGRPRTGMEVAV 356 Query: 362 LNEDGQELAPFETGEICVRGPAVFMGYHNNPEANAKAFKHDWFHTGDLGHVDKDGFLYIT 421 L+ + Q +A E GEICVRGPAVF GYH NPEA AKA + WFHTGDLG +D G LYIT Sbjct: 357 LDAEMQPVATGEIGEICVRGPAVFAGYHANPEATAKALRGGWFHTGDLGRLDARGLLYIT 416 Query: 422 GRSSDMYISGGSNVYPREIEEALLTHPAVSEVAVLGVPDPKWGESGLAVIVCKAGQHA-D 480 GR SDMYISGGSNVYPRE EE LLTHP V+EVAVLGVPD WGE G+AV+V + G A + Sbjct: 417 GRESDMYISGGSNVYPRECEELLLTHPGVAEVAVLGVPDRTWGEVGVAVVVRREGVPAVN 476 Query: 481 GEALLAHLETRIGKYKWPRRFVYWDSMPKSGYGKIVKKQIKALLEEQGD 529 E LLAHL+ + +Y+WPR+FV+WD++PKSGYGKI KK ++ALL E+GD Sbjct: 477 AETLLAHLDGHLARYRWPRQFVFWDALPKSGYGKITKKDVRALLYERGD 525 >ref|XP_002945010.1| PREDICTED: tyrocidine synthase 2-like [Xenopus (Silurana) tropicalis] Length = 531 Score = 654 bits (1686), Expect = 0.0, Method: Composition-based stats. Identities = 323/531 (60%), Positives = 397/531 (74%), Gaps = 8/531 (1%) Query: 3 SKVMNLGRLLSDVARRFPEEPGLILAQGATDGSDRLIPWREINARVDALAHALTRRGVKK 62 ++ MNLG+LL+ A P+ GLI QG+ R W EINARVDA+ AL G+K+ Sbjct: 4 AQAMNLGQLLAQTASLHPDRVGLI--QGS-----RQWTWSEINARVDAMVSALRALGLKQ 56 Query: 63 GDKMLVHSRNNQQIFESAWAAFKMGVVWVPTNFRITPPEAAYLGQSSEACVMLYDRGFAP 122 G+++LV SRNN +FES W AF++G VWVPTN+R+TPPE AYLG SS A MLY+ FA Sbjct: 57 GERILVQSRNNLALFESCWIAFRIGCVWVPTNYRLTPPEIAYLGASSGAKAMLYEADFAE 116 Query: 123 YVDAVKSASPALEHVVALADARPGELDYETLVADGSGDTFREAEVDYDDPLWFFYTSGTT 182 +VDAV+ SPAL+HVV + R E YETLV + A V DDPLWFFYTSGTT Sbjct: 117 HVDAVRVVSPALQHVVCIDRPRDAEHGYETLVENHRCAKPEPASVTCDDPLWFFYTSGTT 176 Query: 183 GHPKAGMLSHGQMAFVVTNHLADLMPGLTHQSRSLVVAPLSHGAGVHAVVNTARGAASIL 242 G PKA +L+HGQM FVVTNHLADL+PG S+ VAPLSHGAG+HA++N ARGAA++L Sbjct: 177 GKPKAAVLTHGQMNFVVTNHLADLIPGTDETDCSIAVAPLSHGAGIHALLNVARGAATVL 236 Query: 243 LSSERLVVEEAWQLVEKYKVDNLFTVPTIVKILVEDESVDRYDHSSLKHVIYAGAPMYRA 302 S++L +E W+LVE+++V NLFTVPTIVK+LVE +VD++DHSSL++VIYAGAPMYRA Sbjct: 237 PESDKLDPDEFWRLVEQHRVSNLFTVPTIVKMLVEHPAVDQHDHSSLRYVIYAGAPMYRA 296 Query: 303 DQVHALKKLGKVLVQYYGLGEVTGNITFLPPYLHFEDDAHPQARVGTCGMPRTGMQVAIL 362 DQ AL+KLGKVLVQY+GLGEVTG IT LPP +H DD P A +GTCG PR GM+VA+L Sbjct: 297 DQKLALRKLGKVLVQYFGLGEVTGCITVLPPRMHSVDDEDPNAPIGTCGYPRIGMEVAVL 356 Query: 363 NEDGQELAPFETGEICVRGPAVFMGYHNNPEANAKAFKHDWFHTGDLGHVDKDGFLYITG 422 +D Q +A E GEIC RGPAV GY+++PEA AKA + WFHTGDLG +D G LYITG Sbjct: 357 GDDLQPVATGEIGEICCRGPAVLAGYYDSPEATAKALRGGWFHTGDLGKLDGRGLLYITG 416 Query: 423 RSSDMYISGGSNVYPREIEEALLTHPAVSEVAVLGVPDPKWGESGLAVIVCKAGQHA-DG 481 R SDMYISGGSNVYPRE+EE LLTHP ++EVAVLGVPD KWGE G+AVIV + G+ D Sbjct: 417 RESDMYISGGSNVYPREVEEVLLTHPGIAEVAVLGVPDEKWGEIGVAVIVRREGEAVLDQ 476 Query: 482 EALLAHLETRIGKYKWPRRFVYWDSMPKSGYGKIVKKQIKALLEEQGDYRL 532 +L HLE R KY+WPR +WD++PKSGYGK+VKK ++ LL E+G+ L Sbjct: 477 SGVLDHLEGRCAKYRWPRHMFFWDALPKSGYGKVVKKDVRRLLVERGEISL 527 >ref|YP_001861065.1| AMP-dependent synthetase and ligase [Burkholderia phymatum STM815] gb|ACC74019.1| AMP-dependent synthetase and ligase [Burkholderia phymatum STM815] Length = 531 Score = 644 bits (1661), Expect = 0.0, Method: Composition-based stats. Identities = 310/526 (58%), Positives = 382/526 (72%), Gaps = 8/526 (1%) Query: 3 SKVMNLGRLLSDVARRFPEEPGLILAQGATDGSDRLIPWREINARVDALAHALTRRGVKK 62 + V NL LL AR+FP+ ++ DR W EI++RVDA+ AL GV+ Sbjct: 4 ASVTNLAHLLRQSARQFPQRTAVV-------HRDRTWNWSEIDSRVDAMVAALRSLGVRP 56 Query: 63 GDKMLVHSRNNQQIFESAWAAFKMGVVWVPTNFRITPPEAAYLGQSSEACVMLYDRGFAP 122 GDK+LV SRN Q+FES W AF++G VWVPTNFR+TPPE AYLG SS AC M+ + F Sbjct: 57 GDKILVQSRNCVQMFESCWVAFRLGAVWVPTNFRLTPPEVAYLGSSSGACAMIVEEDFQE 116 Query: 123 YVDAVKSASPALEHVVALADARPGELDYETLVADGSGDTFREAEVDYDDPLWFFYTSGTT 182 Y DAV++ASP L H+V + R GE YE LVA G +A VDYD PLWFFYTSGTT Sbjct: 117 YADAVRAASPDLRHIVVIGSPRQGEHSYEDLVAANLGTKSEDAVVDYDTPLWFFYTSGTT 176 Query: 183 GHPKAGMLSHGQMAFVVTNHLADLMPGLTHQSRSLVVAPLSHGAGVHAVVNTARGAASIL 242 G PKA +L+HGQMAFVV NHLAD++PGLT S+VVAPLSHGAG+ ++N ARGAA+++ Sbjct: 177 GRPKAAILTHGQMAFVVANHLADVLPGLTELDCSIVVAPLSHGAGIQGLLNVARGAAAVI 236 Query: 243 LSSERLVVEEAWQLVEKYKVDNLFTVPTIVKILVEDESVDRYDHSSLKHVIYAGAPMYRA 302 L SE++ E W LVEK+KV N F VPTI+KILVE +VDR+DHSSL+++ Y GAPMYRA Sbjct: 237 LPSEKMEPEVVWALVEKHKVSNFFAVPTIIKILVEHPAVDRHDHSSLRYINYGGAPMYRA 296 Query: 303 DQVHALKKLGKVLVQYYGLGEVTGNITFLPPYLHFEDDAHPQARVGTCGMPRTGMQVAIL 362 DQ AL KLG+VLVQ++GLGE T IT LPP++H DD P A +G+CG PRTGM+VAIL Sbjct: 297 DQKLALTKLGRVLVQHFGLGEATACITVLPPHMHSADDDDPAANIGSCGRPRTGMEVAIL 356 Query: 363 NEDGQELAPFETGEICVRGPAVFMGYHNNPEANAKAFKHDWFHTGDLGHVDKDGFLYITG 422 + D +L E GEIC RGPAVF GY+ N EA KAF+ WFHTGDLG +D+ G LYITG Sbjct: 357 DADLNKLPAGEVGEICCRGPAVFAGYYGNQEATEKAFRGGWFHTGDLGKLDERGLLYITG 416 Query: 423 RSSDMYISGGSNVYPREIEEALLTHPAVSEVAVLGVPDPKWGESGLAVIVCK-AGQHADG 481 R SDMYISGGSNVYPRE+EE LLTHP+V+EVAVLG+PDPKWGE G+AV+V + D Sbjct: 417 RESDMYISGGSNVYPREVEEILLTHPSVAEVAVLGIPDPKWGEVGVAVVVLRDDAPPVDA 476 Query: 482 EALLAHLETRIGKYKWPRRFVYWDSMPKSGYGKIVKKQIKALLEEQ 527 LL HLE +Y+WP+ +W+S+PKSGYGKI KK+++ L E+ Sbjct: 477 AGLLNHLEGCCARYRWPKHVFFWESLPKSGYGKITKKEVRQKLFER 522