BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.4939.p (219 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777183.1| thiopurine S-methyltransferase [Herbaspirill... 362 2e-98 gb|EFV87718.1| thiopurine S-methyltransferase [Achromobacter xyl... 322 4e-86 gb|EGP47985.1| thiopurine S-methyltransferase [Achromobacter xyl... 315 2e-84 ref|NP_884416.1| thiopurine S-methyltransferase [Bordetella para... 313 1e-83 ref|YP_001632454.1| thiopurine S-methyltransferase [Bordetella p... 313 2e-83 >ref|YP_003777183.1| thiopurine S-methyltransferase [Herbaspirillum seropedicae SmR1] gb|ADJ65275.1| thiopurine S-methyltransferase protein [Herbaspirillum seropedicae SmR1] Length = 219 Score = 362 bits (929), Expect = 2e-98, Method: Composition-based stats. Identities = 180/218 (82%), Positives = 199/218 (91%) Query: 1 MKAEFWLERWRDGRTHFHQSRVTPLLQKYWPALALPQGSQVLVPLAGKSLDMLWLAEQGH 60 M+AEFWLERWRDGRTHFHQSRVTPLLQKYWP+LALP GS VLVPL GKSLDMLWLAEQGH Sbjct: 1 MEAEFWLERWRDGRTHFHQSRVTPLLQKYWPSLALPAGSTVLVPLCGKSLDMLWLAEQGH 60 Query: 61 RVLGVELSELAVEQFFDENRLQPQIRESAYGRHYTAGDVEIICGDIFKLDAALLSACVGV 120 RVLGVELSELA+ QFF E++L P + ESA GRHY AG++E+ICGDIF L+ A L+AC G Sbjct: 61 RVLGVELSELAITQFFSEHQLVPLVHESAQGRHYVAGNIELICGDIFALEEATLAACAGA 120 Query: 121 YDRAALIALPPDMRARYVEEIYGRLPAQARSLLITLEYDQEKMEGPPFSVAEEEVLRLYA 180 YDRAALIALPP MRARYV E+YGRLPAQARSLLITLEYDQ+KM+GPPFSV+EEEVLRLYA Sbjct: 121 YDRAALIALPPAMRARYVTEVYGRLPAQARSLLITLEYDQQKMDGPPFSVSEEEVLRLYA 180 Query: 181 PHSDAVAIDRRDILEKEPKFLERGLRALDTVVYRLQRK 218 PHS+A AIDRRDIL+KEPKFLERGL AL+TVVYRLQR+ Sbjct: 181 PHSEAQAIDRRDILDKEPKFLERGLSALETVVYRLQRR 218 >gb|EFV87718.1| thiopurine S-methyltransferase [Achromobacter xylosoxidans C54] Length = 219 Score = 322 bits (824), Expect = 4e-86, Method: Composition-based stats. Identities = 155/215 (72%), Positives = 177/215 (82%) Query: 1 MKAEFWLERWRDGRTHFHQSRVTPLLQKYWPALALPQGSQVLVPLAGKSLDMLWLAEQGH 60 M AEFWLERWRDGRTHFHQ+RVTPLLQKYWP L++P G +VLVPL GKSLDM+WLA QG+ Sbjct: 1 MDAEFWLERWRDGRTHFHQTRVTPLLQKYWPTLSVPAGGKVLVPLCGKSLDMVWLAAQGY 60 Query: 61 RVLGVELSELAVEQFFDENRLQPQIRESAYGRHYTAGDVEIICGDIFKLDAALLSACVGV 120 +VLGVELS+LAVEQFF EN L+P I ESAYGRHY AG++EIICGDIFKLDA LLS CVG Sbjct: 61 QVLGVELSQLAVEQFFTENELKPVIHESAYGRHYVAGNIEIICGDIFKLDAPLLSHCVGA 120 Query: 121 YDRAALIALPPDMRARYVEEIYGRLPAQARSLLITLEYDQEKMEGPPFSVAEEEVLRLYA 180 YDRAAL+ALP DMR YV +YG+L R LLITL+Y QE+M+GPPF+V + E+ L+ Sbjct: 121 YDRAALVALPADMRGDYVRHVYGQLAPGYRGLLITLDYPQEEMDGPPFAVVDAEMRNLFT 180 Query: 181 PHSDAVAIDRRDILEKEPKFLERGLRALDTVVYRL 215 S AV IDRRDIL KEPKF ERG+ LDTVVYRL Sbjct: 181 GVSPAVIIDRRDILAKEPKFAERGVSRLDTVVYRL 215 >gb|EGP47985.1| thiopurine S-methyltransferase [Achromobacter xylosoxidans AXX-A] Length = 219 Score = 315 bits (808), Expect = 2e-84, Method: Composition-based stats. Identities = 153/215 (71%), Positives = 178/215 (82%) Query: 1 MKAEFWLERWRDGRTHFHQSRVTPLLQKYWPALALPQGSQVLVPLAGKSLDMLWLAEQGH 60 M AEFWLERWRDGRTHFHQ+RVTPLLQKYWP L++P G +VLVPL GKSLDM+WLA QG Sbjct: 1 MDAEFWLERWRDGRTHFHQARVTPLLQKYWPTLSVPAGGKVLVPLCGKSLDMVWLAAQGF 60 Query: 61 RVLGVELSELAVEQFFDENRLQPQIRESAYGRHYTAGDVEIICGDIFKLDAALLSACVGV 120 +VLGVELS+LAVEQFF EN L+P I++SAYGRHY AG++EIICGDIFKLDA LLS CVG Sbjct: 61 QVLGVELSQLAVEQFFVENELKPVIQDSAYGRHYVAGNIEIICGDIFKLDAPLLSHCVGA 120 Query: 121 YDRAALIALPPDMRARYVEEIYGRLPAQARSLLITLEYDQEKMEGPPFSVAEEEVLRLYA 180 YDRAAL+ALP +MR YV +YG+L R LLITL+Y QE+M+GPPF+V + E+ L++ Sbjct: 121 YDRAALVALPVEMRGEYVRHVYGQLSPGYRGLLITLDYPQEEMDGPPFAVVDAEMRALFS 180 Query: 181 PHSDAVAIDRRDILEKEPKFLERGLRALDTVVYRL 215 S AV IDRRDIL KEPKF ERG+ LDTVVYRL Sbjct: 181 GVSPAVIIDRRDILTKEPKFAERGVSRLDTVVYRL 215 >ref|NP_884416.1| thiopurine S-methyltransferase [Bordetella parapertussis 12822] ref|NP_888102.1| thiopurine S-methyltransferase [Bordetella bronchiseptica RB50] sp|Q7W8H4|TPMT_BORPA RecName: Full=Thiopurine S-methyltransferase; AltName: Full=Thiopurine methyltransferase sp|Q7WM36|TPMT_BORBR RecName: Full=Thiopurine S-methyltransferase; AltName: Full=Thiopurine methyltransferase emb|CAE32054.1| thiopurine S-methyltransferase [Bordetella bronchiseptica RB50] emb|CAE37460.1| thiopurine S-methyltransferase [Bordetella parapertussis] Length = 219 Score = 313 bits (803), Expect = 1e-83, Method: Composition-based stats. Identities = 153/219 (69%), Positives = 183/219 (83%) Query: 1 MKAEFWLERWRDGRTHFHQSRVTPLLQKYWPALALPQGSQVLVPLAGKSLDMLWLAEQGH 60 M A+FWL+RWR+GRTHFHQ+RVTPLLQKYWPAL +P G QVLVPLAGKSLDM+WLA QG Sbjct: 1 MDADFWLDRWREGRTHFHQTRVTPLLQKYWPALDVPAGGQVLVPLAGKSLDMVWLAGQGL 60 Query: 61 RVLGVELSELAVEQFFDENRLQPQIRESAYGRHYTAGDVEIICGDIFKLDAALLSACVGV 120 RVLGVELS+LAVEQFFDEN L+P+I +SA GRHY AG++E+ICGD+F L+ A L+AC GV Sbjct: 61 RVLGVELSQLAVEQFFDENGLRPEIHQSAQGRHYVAGNLELICGDVFALEDATLAACAGV 120 Query: 121 YDRAALIALPPDMRARYVEEIYGRLPAQARSLLITLEYDQEKMEGPPFSVAEEEVLRLYA 180 YDRAAL+ALP MR RY E+YGRL R +LITL+Y Q++MEGPPFSV + EV LYA Sbjct: 121 YDRAALVALPEPMRKRYAREVYGRLGRGCRGILITLDYPQDQMEGPPFSVDDAEVQALYA 180 Query: 181 PHSDAVAIDRRDILEKEPKFLERGLRALDTVVYRLQRKG 219 H++A IDRRDIL+KEPKF +RG+ LDT+VYRL+R G Sbjct: 181 GHTEARLIDRRDILDKEPKFNQRGVARLDTLVYRLERLG 219 >ref|YP_001632454.1| thiopurine S-methyltransferase [Bordetella petrii DSM 12804] sp|A9I3K3|TPMT_BORPD RecName: Full=Thiopurine S-methyltransferase; AltName: Full=Thiopurine methyltransferase emb|CAP44186.1| thiopurine S-methyltransferase [Bordetella petrii] Length = 219 Score = 313 bits (801), Expect = 2e-83, Method: Composition-based stats. Identities = 151/219 (68%), Positives = 175/219 (79%) Query: 1 MKAEFWLERWRDGRTHFHQSRVTPLLQKYWPALALPQGSQVLVPLAGKSLDMLWLAEQGH 60 M AEFWLERWRDGRTHFHQ RVTPLL KYWP L LP G +VLVPL GK+LDM+WLA+QGH Sbjct: 1 MDAEFWLERWRDGRTHFHQQRVTPLLAKYWPTLQLPPGCRVLVPLCGKTLDMVWLAQQGH 60 Query: 61 RVLGVELSELAVEQFFDENRLQPQIRESAYGRHYTAGDVEIICGDIFKLDAALLSACVGV 120 +VLGVELS LAVEQFF EN LQ +RE+ G +Y+AGD+ I CGDIF L A +L CVG Sbjct: 61 QVLGVELSSLAVEQFFAENGLQATVREAGPGTYYSAGDISIYCGDIFDLGADVLGDCVGA 120 Query: 121 YDRAALIALPPDMRARYVEEIYGRLPAQARSLLITLEYDQEKMEGPPFSVAEEEVLRLYA 180 +DRAAL+ALP MR RY +YG+L A R LLITL+YDQ +M+GPPFSV ++EV +YA Sbjct: 121 FDRAALVALPAAMRPRYARHVYGQLSAAYRGLLITLDYDQSQMDGPPFSVRDDEVQAIYA 180 Query: 181 PHSDAVAIDRRDILEKEPKFLERGLRALDTVVYRLQRKG 219 HS+AV IDRRDIL KEPKF ERGL LDT+VYRLQR+G Sbjct: 181 GHSEAVLIDRRDILSKEPKFAERGLTQLDTLVYRLQRQG 219