BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.4852.p (478 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775892.1| two component heavy metal sensor histidine k... 761 0.0 ref|YP_995151.1| heavy metal sensor signal transduction histidin... 575 e-162 ref|YP_004751898.1| heavy metal sensor histidine kinase [Collimo... 479 e-133 gb|EGP44711.1| heavy metal sensor signal transduction histidine ... 435 e-119 ref|YP_004156914.1| heavy metal sensor signal transduction histi... 418 e-114 >ref|YP_003775892.1| two component heavy metal sensor histidine kinase [Herbaspirillum seropedicae SmR1] gb|ADJ63984.1| two component heavy metal sensor histidine kinase protein [Herbaspirillum seropedicae SmR1] Length = 467 Score = 761 bits (1964), Expect = 0.0, Method: Composition-based stats. Identities = 404/464 (87%), Positives = 423/464 (91%) Query: 15 RRLPLRQSITARLVLMSAASALLIFAVAGVVLYTVLKGELLRHERDALFTTLNDISYQIE 74 R LPLRQSITARLV MSAASALLIFA+ G+VLYTVLKGELLRHERD L TTLNDISYQI Sbjct: 4 RWLPLRQSITARLVWMSAASALLIFALTGMVLYTVLKGELLRHERDGLVTTLNDISYQIG 63 Query: 75 RAGNTERWARVQLKLSTLSQADQHVFFWIASDDPRYTYGDLTRLAPSAINHADGKQVGRL 134 RAGNTERW RVQ KL+TLSQADQHV FWI+S D R+TYGDL+RLAP AI +G VGRL Sbjct: 64 RAGNTERWGRVQAKLATLSQADQHVSFWISSSDARFTYGDLSRLAPQAIRADEGNSVGRL 123 Query: 135 HLPGRAYPLHIMTRTLPAFEDRPEVRVTVGVDGAPYFEMRRTFLLATSISSLLGIVLAVI 194 HLPGR YPLHIMTRTLPAFE+RP V VTVGVDG PYFEMRRTFLLATS+ SLLGIVLAVI Sbjct: 124 HLPGRRYPLHIMTRTLPAFEERPAVDVTVGVDGEPYFEMRRTFLLATSVFSLLGIVLAVI 183 Query: 195 SSYWIARAGLAPLRRMSARAQSFSPRKLSARMPVEALPEELSVLADAFNGALERIEQAYT 254 SSYWIARAGLAPLR+MS RAQSFSPRKLSARMPVEA+P+ELSVLA AFNGAL+RIE AYT Sbjct: 184 SSYWIARAGLAPLRQMSDRAQSFSPRKLSARMPVEAMPQELSVLALAFNGALDRIEDAYT 243 Query: 255 QLEAFNADVAHELRTPLANLIGETQVALARERSAGEFKDVLQSNLEELDRIRSIVNDMLF 314 QLEAFNADVAHELRTPLANLIGETQVALARERSAGEFKDVLQSNLEELDRIRSIVNDMLF Sbjct: 244 QLEAFNADVAHELRTPLANLIGETQVALARERSAGEFKDVLQSNLEELDRIRSIVNDMLF 303 Query: 315 LARSDQGEAATARVPVRVAEAVQKTVDFFEFVLDDTGMSITVAGDLEATATMETALFKRA 374 LARSDQGEAATARVP RVA+ VQKTVDFFEFVLDD+GM I VAGD EATA METALFKRA Sbjct: 304 LARSDQGEAATARVPARVADEVQKTVDFFEFVLDDSGMRIEVAGDTEATAMMETALFKRA 363 Query: 375 LTNLIQNAIQHSPQGAQLRIDISGGEEMVRVAVTNPGPAIDEQHLPRLFDRFYRVDSARQ 434 LTNLIQNAIQHSP+GA LRIDI+ EE VRVAV+NPG IDE HLPRLFDRFYRVDSARQ Sbjct: 364 LTNLIQNAIQHSPEGALLRIDIACQEETVRVAVSNPGKPIDEHHLPRLFDRFYRVDSARQ 423 Query: 435 DINGSHGHGLGLAIVKAVARMHGGRAFASSSGGHNTIGFTIARQ 478 DINGSHGHGLGLAIVKAVARMHGGRAFASS G N+IGFTIARQ Sbjct: 424 DINGSHGHGLGLAIVKAVARMHGGRAFASSKEGVNSIGFTIARQ 467 >ref|YP_995151.1| heavy metal sensor signal transduction histidine kinase [Verminephrobacter eiseniae EF01-2] gb|ABM56133.1| heavy metal sensor signal transduction histidine kinase [Verminephrobacter eiseniae EF01-2] Length = 458 Score = 575 bits (1482), Expect = e-162, Method: Composition-based stats. Identities = 292/460 (63%), Positives = 360/460 (78%), Gaps = 4/460 (0%) Query: 19 LRQSITARLVLMSAASALLIFAVAGVVLYTVLKGELLRHERDALFTTLNDISYQIERAGN 78 ++ SI ARLV+M AA+AL+IF++ G VLY V+ ELL HER++L TT DI Y + RAG Sbjct: 1 MKNSIIARLVIMFAAAALIIFSLIGSVLYAVVDNELLHHERNSLVTTFKDIEYMVSRAGT 60 Query: 79 TERWARVQLKLSTLSQADQHVFFWIASDDPRYTYG-DLTRLAPSAINHADGKQVGRLHLP 137 TERWA VQ+KL TL+ AD V FWI SDDPR+ YG DL L A NH + +GR+ + Sbjct: 61 TERWAHVQVKLDTLTPADGKVRFWIFSDDPRFGYGKDLAELHEFA-NHPN--NLGRMSIK 117 Query: 138 GRAYPLHIMTRTLPAFEDRPEVRVTVGVDGAPYFEMRRTFLLATSISSLLGIVLAVISSY 197 G+ YPLH +TR LPA+ DRP +R+TVGVD A YFE RTF+ A + SL G++L ++ Y Sbjct: 118 GKKYPLHTLTRILPAYLDRPAIRLTVGVDAASYFETLRTFVAAMTGLSLAGVLLVILCGY 177 Query: 198 WIARAGLAPLRRMSARAQSFSPRKLSARMPVEALPEELSVLADAFNGALERIEQAYTQLE 257 WIAR GL PL++MS +AQ+ SP+ LS R+ + ALP+ELS LA AFNGAL+R+E AY QLE Sbjct: 178 WIARTGLQPLKKMSDKAQTLSPKTLSERLTLSALPDELSDLAQAFNGALDRMENAYKQLE 237 Query: 258 AFNADVAHELRTPLANLIGETQVALARERSAGEFKDVLQSNLEELDRIRSIVNDMLFLAR 317 AFNADVAHELRTPLANLIGETQVAL+RERSA EF+ VLQSNLEE+DR+RSI+NDMLFLAR Sbjct: 238 AFNADVAHELRTPLANLIGETQVALSRERSAPEFESVLQSNLEEMDRLRSIINDMLFLAR 297 Query: 318 SDQGEAATARVPVRVAEAVQKTVDFFEFVLDDTGMSITVAGDLEATATMETALFKRALTN 377 DQGEAAT V +A+ VQKT+DFFEFVLD+TGM + ++GD ATA +ET+LF+RALTN Sbjct: 298 CDQGEAATGLVHALIADEVQKTMDFFEFVLDETGMRVEISGDTHATALIETSLFRRALTN 357 Query: 378 LIQNAIQHSPQGAQLRIDISGGEEMVRVAVTNPGPAIDEQHLPRLFDRFYRVDSARQDIN 437 L+QNAIQHSP GA + + I V++AV+NPG +++ HLPRLFDRFYRVD+AR+DIN Sbjct: 358 LLQNAIQHSPAGACIEVAIDAKNHGVQIAVSNPGEPVEQGHLPRLFDRFYRVDTARRDIN 417 Query: 438 GSHGHGLGLAIVKAVARMHGGRAFASSSGGHNTIGFTIAR 477 G HGHGLGLAIVKA+A MHGG FA+S+GG TIGFT AR Sbjct: 418 GIHGHGLGLAIVKAIALMHGGSVFAASTGGVTTIGFTTAR 457 >ref|YP_004751898.1| heavy metal sensor histidine kinase [Collimonas fungivorans Ter331] gb|AEK61075.1| Heavy metal sensor histidine kinase [Collimonas fungivorans Ter331] Length = 465 Score = 479 bits (1234), Expect = e-133, Method: Composition-based stats. Identities = 258/459 (56%), Positives = 334/459 (72%), Gaps = 4/459 (0%) Query: 19 LRQSITARLVLMSAASALLIFAVAGVVLYTVLKGELLRHERDALFTTLNDISYQIERAGN 78 +++SIT RLV M A +ALLIF++ G LY VL+ EL RH++D L T D Y I G+ Sbjct: 1 MKRSITVRLVAMFALAALLIFSLIGSALYGVLQRELARHQQDELNTRFLDTRYMIGHNGD 60 Query: 79 TERWARVQLKLSTLSQADQHVFFWIASDDPRYTYGDLTRLAPSAINHADGKQVGRLHLPG 138 RW RVQ KL TL+ AD + +W+ SDDPR+ YG + +G +G + L G Sbjct: 61 PARWPRVQTKLETLTPADGSIRYWVLSDDPRFQYGKGLADVEQLDRNPNG--MGIMSLRG 118 Query: 139 RAYPLHIMTRTLPAFEDRPEVRVTVGVDGAPYFEMRRTFLLATSISSLLGIVLAVISSYW 198 R YPLH M T+ F++RP VR+ V VD APY F++A SLLG++L ++ YW Sbjct: 119 REYPLHTMIGTIEPFQERPAVRLIVAVDAAPYMHTLHAFMIALVGLSLLGVLLVMLLGYW 178 Query: 199 IARAGLAPLRRMSARAQSFSPRKLSARMPVEALPEELSVLADAFNGALERIEQAYTQLEA 258 IA+ GL PL+++S+ AQS P+ LS R+ + LP ELS L AFNG LER+E AY QLEA Sbjct: 179 IAQVGLRPLKQLSSAAQSLGPKTLSQRLQISPLPGELSDLTIAFNGVLERMEGAYNQLEA 238 Query: 259 FNADVAHELRTPLANLIGETQVALARERSAGEFKDVLQSNLEELDRIRSIVNDMLFLARS 318 FNADVAHELRTPLANLIGETQVAL+R+R+A +F++VLQSNLEEL+R+RSI+NDMLFLAR+ Sbjct: 239 FNADVAHELRTPLANLIGETQVALSRQRTAPQFEEVLQSNLEELERLRSIINDMLFLARA 298 Query: 319 DQGEAATARVPVRVAEAVQKTVDFFEFVLDDTGMSITVAGDLEATATMETALFKRALTNL 378 DQGEAAT+ V +A+ V KTV+FFEF+LDD+ M++ VAGD+ A A++ET+LFKRA++NL Sbjct: 299 DQGEAATSLVRTSIAQEVGKTVEFFEFLLDDSKMTVKVAGDVSAEASIETSLFKRAMSNL 358 Query: 379 IQNAIQHSPQGAQLRIDISGGEEMVRVAVTNPGPAIDEQHLPRLFDRFYRVDSARQDING 438 + NAIQHS GA + + I+ E +R+AV+NPG I + HLPRLFDRFYRVD+AR D + Sbjct: 359 LHNAIQHSSPGAAIAVTITQEPEAIRIAVSNPGKPISDNHLPRLFDRFYRVDAARNDKDQ 418 Query: 439 S--HGHGLGLAIVKAVARMHGGRAFASSSGGHNTIGFTI 475 S HGHGLGLAIVKA+A+MHGG FA S+ G TIGF+I Sbjct: 419 SQLHGHGLGLAIVKAIAKMHGGGVFADSTDGTTTIGFSI 457 >gb|EGP44711.1| heavy metal sensor signal transduction histidine kinase [Achromobacter xylosoxidans AXX-A] Length = 460 Score = 435 bits (1118), Expect = e-119, Method: Composition-based stats. Identities = 247/462 (53%), Positives = 324/462 (70%), Gaps = 10/462 (2%) Query: 19 LRQSITARLVLMSAASALLIFAVAGVVLYTVLKGELLRHERDALFTTLNDISYQIERAGN 78 ++ S+ +RLV+M A +A FA+ GV LY VL +L R ++DAL TT +++SY + R+G+ Sbjct: 1 MKSSLKSRLVVMFAVAAAATFALTGVALYGVLDRQLDRIQQDALRTTAHEVSYSLTRSGD 60 Query: 79 TERWARVQLKLSTLSQADQHVFFWIASDDPRYTYG----DLTRLAPSAINHADGKQVGRL 134 ERW R + KL TL+ AD + FW+ SDDP Y YG D+ RL HADG G + Sbjct: 61 PERWGRFKAKLDTLTPADGSLRFWVLSDDPAYEYGKGLADVDRLE----RHADG--FGTI 114 Query: 135 HLPGRAYPLHIMTRTLPAFEDRPEVRVTVGVDGAPYFEMRRTFLLATSISSLLGIVLAVI 194 LP R L +T T+ AF+ RP VR+ VG+D APY R FL A + SL I+L + Sbjct: 115 TLPDRENELLTITVTVEAFQQRPRVRLIVGMDSAPYAHTLRYFLWAMAGLSLTAILLVGL 174 Query: 195 SSYWIARAGLAPLRRMSARAQSFSPRKLSARMPVEALPEELSVLADAFNGALERIEQAYT 254 +W+AR GL PL R+SA A++ P LS R+ + ALP EL LA +FNGAL R+E AY Sbjct: 175 LGFWVARLGLRPLNRLSAEARALRPSALSQRLSMAALPVELEDLATSFNGALARLEGAYN 234 Query: 255 QLEAFNADVAHELRTPLANLIGETQVALARERSAGEFKDVLQSNLEELDRIRSIVNDMLF 314 QLE FNADVAHELRTPL NLIG+TQVAL+R R +GE ++VLQSNLEELDR+R++VNDMLF Sbjct: 235 QLEDFNADVAHELRTPLTNLIGQTQVALSRPRGSGELREVLQSNLEELDRLRAMVNDMLF 294 Query: 315 LARSDQGEAATARVPVRVAEAVQKTVDFFEFVLDDTGMSITVAGDLEATATMETALFKRA 374 LAR+DQGEAAT R+ +A+ V KTV+FFEF+LD+ GM + + G+ +A A ++TALF+RA Sbjct: 295 LARADQGEAATGRIHAVLADEVGKTVEFFEFLLDEAGMRVRIQGERDAVALIDTALFRRA 354 Query: 375 LTNLIQNAIQHSPQGAQLRIDISGGEEMVRVAVTNPGPAIDEQHLPRLFDRFYRVDSARQ 434 +TNL+QNAIQ+S GA++ +DI+ + ++ VAV+NPGP I QHLP LF RFYRVD+AR Sbjct: 355 VTNLLQNAIQYSSAGAEITVDIARRDGLLEVAVSNPGPPIAPQHLPHLFQRFYRVDAARG 414 Query: 435 DINGSHGHGLGLAIVKAVARMHGGRAFASSSGGHNTIGFTIA 476 H HGLGLAIVKAVA MHGG A+S GG + F++ Sbjct: 415 GDGVEHSHGLGLAIVKAVAAMHGGSVSAASGGGVTRVAFSVG 456 >ref|YP_004156914.1| heavy metal sensor signal transduction histidine kinase [Variovorax paradoxus EPS] gb|ADU38803.1| heavy metal sensor signal transduction histidine kinase [Variovorax paradoxus EPS] Length = 464 Score = 418 bits (1075), Expect = e-114, Method: Composition-based stats. Identities = 251/460 (54%), Positives = 324/460 (70%), Gaps = 2/460 (0%) Query: 19 LRQSITARLVLMSAASALLIFAVAGVVLYTVLKGELLRHERDALFTTLNDISYQIERAGN 78 ++ SIT RLV M AA+AL FA+ G L+ VL EL RH+ + L TTL + Y I G Sbjct: 4 VKGSITVRLVAMFAAAALATFALIGAALHGVLVRELERHQYEELDTTLKSLQYWIGAIGT 63 Query: 79 TERWARVQLKLSTLSQADQHVFFWIASDDPRYTYGDLTRLAPSAINHADGKQVGRLHLPG 138 +RW+RVQ ++ L+ D V FW+ SDDPR+ YG A+G+ L LPG Sbjct: 64 ADRWSRVQTRMDALTPEDGSVRFWVLSDDPRFQYGKGLAELDGLTREANGRSSSIL-LPG 122 Query: 139 RAYPLHIMTRTLPAFEDRPEVRVTVGVDGAPYFEMRRTFLLATSISSLLGIVLAVISSYW 198 + P ++ +P FE RP VR+ VG + PY R+TFL A + L G+++ V++ YW Sbjct: 123 QERPFRTLSVHIPPFEGRPAVRLIVGRNSEPYERTRKTFLSALLMLGLGGVLVVVLAGYW 182 Query: 199 IARAGLAPLRRMSARAQSFSPRKLSARMPVEALPEELSVLADAFNGALERIEQAYTQLEA 258 IAR GL PL R+S AQ+ P+ LS R+ ALP ELS LA+AFNGAL R+E+AY QLEA Sbjct: 183 IARVGLRPLERLSGEAQALRPKTLSQRLQTTALPVELSALAEAFNGALSRLEEAYGQLEA 242 Query: 259 FNADVAHELRTPLANLIGETQVALARERSAGEFKDVLQSNLEELDRIRSIVNDMLFLARS 318 FNADVAHELRTPLANLIG TQVAL+R+RSAG+F++VLQ+NLE+L+R+RSIVNDMLFLAR+ Sbjct: 243 FNADVAHELRTPLANLIGSTQVALSRQRSAGDFEEVLQANLEDLERLRSIVNDMLFLARA 302 Query: 319 DQGEAATARVPVRVAEAVQKTVDFFEFVLDDTGMSITVAGDLEATATMETALFKRALTNL 378 D+GE AT V VA V+KT+DFFEFVLD++ + +AGD++A A +E+ALF+RA++NL Sbjct: 303 DRGEVATGLVLTPVALEVRKTIDFFEFVLDESRTQVGIAGDVQAEARLESALFRRAMSNL 362 Query: 379 IQNAIQHSPQGAQLRIDISGGEEMVRVAVTNPGPAIDEQHLPRLFDRFYRVDSARQD-IN 437 +QNAI+HS GAQ+ + + G +AV+NPG AIDE HL LFDRFYRVD+AR D Sbjct: 363 LQNAIEHSTPGAQITVTLREGPAATWIAVSNPGAAIDEAHLQHLFDRFYRVDAARNDGGG 422 Query: 438 GSHGHGLGLAIVKAVARMHGGRAFASSSGGHNTIGFTIAR 477 HGHGLGLAIVKAVA MHGG+ ASS GG NT F+++R Sbjct: 423 EHHGHGLGLAIVKAVASMHGGQVSASSEGGVNTFAFSVSR 462