BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.4549.p (373 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777040.1| bifunctional diaminohydroxyphosphoribosyl am... 654 0.0 ref|YP_004754043.1| 5-amino-6-(5-phosphoribosylamino)uracil redu... 509 e-142 ref|YP_001354124.1| 5-amino-6-(5-phosphoribosylamino)uracil redu... 506 e-141 ref|YP_001100624.1| bifunctional diaminohydroxyphosphoribosylami... 484 e-134 ref|ZP_08273466.1| Diamino hydroxy phospho ribosyl amin opyrimid... 479 e-133 >ref|YP_003777040.1| bifunctional diaminohydroxyphosphoribosyl aminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino) uracil reductase [Herbaspirillum seropedicae SmR1] gb|ADJ65132.1| bifunctional enzyme: diaminohydroxyphosphoribosyl aminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino) uracil reductase protein [Herbaspirillum seropedicae SmR1] Length = 354 Score = 654 bits (1688), Expect = 0.0, Method: Composition-based stats. Identities = 332/353 (94%), Positives = 347/353 (98%) Query: 20 MALALLQAGFGMLDTTPNPRVGCVIVKDRRIIGAGFTQPPGGNHAEIQAMADAAARGHDV 79 MALAL+QAGFGMLDTTPNPRVGCVIVKD+RIIGAGFTQPPGGNHAEIQAMADAAARGHDV Sbjct: 1 MALALIQAGFGMLDTTPNPRVGCVIVKDQRIIGAGFTQPPGGNHAEIQAMADAAARGHDV 60 Query: 80 RGATVYVTLEPCSHFGRTPPCADALVRAGVARVVAAIADPNPLVAGQGLARLQAAGIEVA 139 RGATVYVTLEPCSHFGRTPPCADAL+RAGVARVVAAIADPNP+VAGQGLARLQAAGIEV+ Sbjct: 61 RGATVYVTLEPCSHFGRTPPCADALIRAGVARVVAAIADPNPMVAGQGLARLQAAGIEVS 120 Query: 140 CGMLEEEAREINIGFLHRMRTGRPWVRMKSAASLDGKTALHNGVSQWITSQAARDDGHIW 199 CG+LEEEAR+INIGFLHRMRTGRPWVRMKSAASLDGKTALHNGVSQWIT QAARDDGHIW Sbjct: 121 CGLLEEEARDINIGFLHRMRTGRPWVRMKSAASLDGKTALHNGVSQWITGQAARDDGHIW 180 Query: 200 RARACAIMAGIGTIQKDDAQLTVRAIDTPRQPRRIVVDSKLIVSPEARVIQGGNTWVFTA 259 RARACAIMAGIGTIQKDDAQLTVRAI+TPRQPRRIV+DSKLIVSPEARVIQGGNTWVFTA Sbjct: 181 RARACAIMAGIGTIQKDDAQLTVRAIETPRQPRRIVIDSKLIVSPEARVIQGGNTWVFTA 240 Query: 260 TDDREKRAALEAEGAEVILLDNAEGKVDLPGLVRELGQRQINELHVEAGAKLNGALIRAG 319 TDDR+KRAALEAEGAEVILL N +GKVDLPGL+RELGQRQINELHVEAGA+LNGAL+R G Sbjct: 241 TDDRDKRAALEAEGAEVILLANEQGKVDLPGLMRELGQRQINELHVEAGARLNGALLREG 300 Query: 320 CVDELLVYLAPALIGDGRNMFELPPLEDLSGKIGIHFHEVKQVGPDLRILARF 372 CVDELLVYLAP+LIGDGRNMFELPPLEDLSGKIGI FHEVKQVG DLRILARF Sbjct: 301 CVDELLVYLAPSLIGDGRNMFELPPLEDLSGKIGIRFHEVKQVGADLRILARF 353 >ref|YP_004754043.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Collimonas fungivorans Ter331] gb|AEK63220.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Collimonas fungivorans Ter331] Length = 382 Score = 509 bits (1311), Expect = e-142, Method: Composition-based stats. Identities = 252/363 (69%), Positives = 304/363 (83%), Gaps = 1/363 (0%) Query: 11 FDIENDQQAMALALLQAGFGMLDTTPNPRVGCVIVKDRRIIGAGFTQPPGGNHAEIQAMA 70 F + +Q M+ AL A G+L + PNP VGCVIVKD ++IG+GFTQPPGGNHAEIQA+ Sbjct: 19 FPMTAVEQLMSQALQLAENGLLSSAPNPAVGCVIVKDGQVIGSGFTQPPGGNHAEIQALQ 78 Query: 71 DAAARGHDVRGATVYVTLEPCSHFGRTPPCADALVRAGVARVVAAIADPNPLVAGQGLAR 130 DAAA+GHDVRGATVYVTLEPCSHFGRTPPCADALV AGVA+VVAAI DPNPLVAGQG+AR Sbjct: 79 DAAAKGHDVRGATVYVTLEPCSHFGRTPPCADALVLAGVAKVVAAIGDPNPLVAGQGMAR 138 Query: 131 LQAAGIEVACGMLEEEAREINIGFLHRMRTGRPWVRMKSAASLDGKTALHNGVSQWITSQ 190 LQAAGI V G+L +ARE+NIGF RM+TG+PWVR+K AASLDGKTALHNG SQWITSQ Sbjct: 139 LQAAGIAVESGVLAAQARELNIGFFTRMQTGKPWVRLKVAASLDGKTALHNGQSQWITSQ 198 Query: 191 AARDDGHIWRARACAIMAGIGTIQKDDAQLTVRAI-DTPRQPRRIVVDSKLIVSPEARVI 249 AARDDGH+WRARA AI+ GIGT+++D+ QLTVR + RQP R++VDSKL +SP+A+++ Sbjct: 199 AARDDGHMWRARAGAILTGIGTVKEDNPQLTVRTVPPILRQPLRVIVDSKLSISPDAKIL 258 Query: 250 QGGNTWVFTATDDREKRAALEAEGAEVILLDNAEGKVDLPGLVRELGQRQINELHVEAGA 309 GG +F+AT D K+A LE +GAEV++L NA+GKVDLP ++ ELG+RQ+NELHVEAG+ Sbjct: 259 AGGGNLIFSATADANKQALLEQQGAEVVVLSNADGKVDLPQVILELGKRQVNELHVEAGS 318 Query: 310 KLNGALIRAGCVDELLVYLAPALIGDGRNMFELPPLEDLSGKIGIHFHEVKQVGPDLRIL 369 KLN +LIR CVDELLVYLAP+++GDGR MF LP LE+L K+ + FHE+KQVG DLRIL Sbjct: 319 KLNASLIREHCVDELLVYLAPSILGDGRGMFSLPALENLDHKLSLKFHEIKQVGEDLRIL 378 Query: 370 ARF 372 ARF Sbjct: 379 ARF 381 >ref|YP_001354124.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Janthinobacterium sp. Marseille] gb|ABR88862.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Janthinobacterium sp. Marseille] Length = 363 Score = 506 bits (1302), Expect = e-141, Method: Composition-based stats. Identities = 254/361 (70%), Positives = 294/361 (81%) Query: 12 DIENDQQAMALALLQAGFGMLDTTPNPRVGCVIVKDRRIIGAGFTQPPGGNHAEIQAMAD 71 +I +D Q + LAL A GM TTPNPRVGCVIVK+ ++IG+G+TQP G HAE+QA+ D Sbjct: 2 EIHSDVQGIRLALELAAKGMFTTTPNPRVGCVIVKENKVIGSGYTQPVGHAHAEVQALND 61 Query: 72 AAARGHDVRGATVYVTLEPCSHFGRTPPCADALVRAGVARVVAAIADPNPLVAGQGLARL 131 AA RG DV G+TVYVTLEPCSH GRTPPCADAL++A VARVVAAIADPNPLVAGQGLARL Sbjct: 62 AADRGFDVSGSTVYVTLEPCSHHGRTPPCADALIKARVARVVAAIADPNPLVAGQGLARL 121 Query: 132 QAAGIEVACGMLEEEAREINIGFLHRMRTGRPWVRMKSAASLDGKTALHNGVSQWITSQA 191 +AAGI+V+CG+LE EARE+NIGFL RM+ G+PWVRMKSAASLDG TALHNG+SQWIT Sbjct: 122 EAAGIQVSCGVLEAEAREMNIGFLSRMQHGKPWVRMKSAASLDGMTALHNGISQWITGDE 181 Query: 192 ARDDGHIWRARACAIMAGIGTIQKDDAQLTVRAIDTPRQPRRIVVDSKLIVSPEARVIQG 251 AR DGH WRARACAI+ GIGT+ +DD QLTVRAIDTPRQP+RIV+DS L +SP ARV+ G Sbjct: 182 ARADGHYWRARACAILTGIGTVMEDDPQLTVRAIDTPRQPQRIVIDSHLQISPHARVLSG 241 Query: 252 GNTWVFTATDDREKRAALEAEGAEVILLDNAEGKVDLPGLVRELGQRQINELHVEAGAKL 311 G T + A + EK L G E+I+L NA GKVDL L++ELG+RQINELHVEAG KL Sbjct: 242 GGTLIVAAQANPEKEKPLRDLGHEIIVLPNAGGKVDLAALMQELGRRQINELHVEAGFKL 301 Query: 312 NGALIRAGCVDELLVYLAPALIGDGRNMFELPPLEDLSGKIGIHFHEVKQVGPDLRILAR 371 NG+LIR GCVDELLVYLAP L+GD + MF LPPLE L K + FHEVKQ+G DLRILAR Sbjct: 302 NGSLIREGCVDELLVYLAPTLLGDAQRMFNLPPLESLEHKKNLTFHEVKQIGADLRILAR 361 Query: 372 F 372 F Sbjct: 362 F 362 >ref|YP_001100624.1| bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal)/5-amino-6-(5-phosphoribosylamino) uracil reductase [Herminiimonas arsenicoxydans] emb|CAL62503.1| bifunctional riboflavin biosynthesis protein ribD [Includes: Diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase); 5-amino-6-(5-phosphoribosylamino)uracil reductase (HTP reductase)] [Herminiimonas arsenicoxydans] Length = 363 Score = 484 bits (1245), Expect = e-134, Method: Composition-based stats. Identities = 253/361 (70%), Positives = 294/361 (81%) Query: 12 DIENDQQAMALALLQAGFGMLDTTPNPRVGCVIVKDRRIIGAGFTQPPGGNHAEIQAMAD 71 +I +D Q + LAL A GM T PNPRVGCVIVK+ ++IG+G+TQP G HAE+QA+ D Sbjct: 2 EIHSDVQGIRLALELAARGMFTTAPNPRVGCVIVKENQVIGSGYTQPAGHAHAEVQALND 61 Query: 72 AAARGHDVRGATVYVTLEPCSHFGRTPPCADALVRAGVARVVAAIADPNPLVAGQGLARL 131 AA +G+DV G+TVYVTLEPCSH GRTPPCADAL+RA VARVVAAIADPNPLVAGQGLARL Sbjct: 62 AANKGYDVAGSTVYVTLEPCSHHGRTPPCADALIRARVARVVAAIADPNPLVAGQGLARL 121 Query: 132 QAAGIEVACGMLEEEAREINIGFLHRMRTGRPWVRMKSAASLDGKTALHNGVSQWITSQA 191 +AAGIEVACG+LE EAREINIGFL RM+ G+PWVRMKSAASLDG TALHNG+SQWIT Sbjct: 122 EAAGIEVACGVLEAEAREINIGFLSRMQHGKPWVRMKSAASLDGMTALHNGISQWITGDE 181 Query: 192 ARDDGHIWRARACAIMAGIGTIQKDDAQLTVRAIDTPRQPRRIVVDSKLIVSPEARVIQG 251 AR DGH+WRARACAI+ GIGT+++DD QLTVRAID PRQP+RIV+DS+L +SP ARV+ G Sbjct: 182 ARADGHVWRARACAILTGIGTVREDDPQLTVRAIDIPRQPQRIVIDSQLQISPHARVLSG 241 Query: 252 GNTWVFTATDDREKRAALEAEGAEVILLDNAEGKVDLPGLVRELGQRQINELHVEAGAKL 311 G TW+ A + L G E+I+L NA+GKVDLP L+ ELG+RQINELHVEAG KL Sbjct: 242 GGTWIVAAQAHPAREKILRDLGNEIIVLPNADGKVDLPALMLELGRRQINELHVEAGFKL 301 Query: 312 NGALIRAGCVDELLVYLAPALIGDGRNMFELPPLEDLSGKIGIHFHEVKQVGPDLRILAR 371 NG+LIR CVDELLVYLAP L+GD + MF LP LE L K + FHEVKQ+G DLRILAR Sbjct: 302 NGSLIREDCVDELLVYLAPTLLGDAQRMFNLPVLESLEQKKNMTFHEVKQIGADLRILAR 361 Query: 372 F 372 F Sbjct: 362 F 362 >ref|ZP_08273466.1| Diamino hydroxy phospho ribosyl amin opyrimidine deaminase [Oxalobacteraceae bacterium IMCC9480] gb|EGF33053.1| Diamino hydroxy phospho ribosyl amin opyrimidine deaminase [Oxalobacteraceae bacterium IMCC9480] Length = 363 Score = 479 bits (1234), Expect = e-133, Method: Composition-based stats. Identities = 248/360 (68%), Positives = 294/360 (81%) Query: 13 IENDQQAMALALLQAGFGMLDTTPNPRVGCVIVKDRRIIGAGFTQPPGGNHAEIQAMADA 72 I NDQQ MALAL A GM T PNPRVGCV+V+D ++GAG TQ G HAEIQA+ADA Sbjct: 3 IANDQQGMALALEWAAKGMFITAPNPRVGCVVVRDGVVLGAGHTQAAGQAHAEIQALADA 62 Query: 73 AARGHDVRGATVYVTLEPCSHFGRTPPCADALVRAGVARVVAAIADPNPLVAGQGLARLQ 132 ARG+ V GAT+YVTLEPCSH GRTPPCADA++RAGV RVV+AIADPNPLVAG GL RL+ Sbjct: 63 QARGNSVTGATLYVTLEPCSHHGRTPPCADAIIRAGVVRVVSAIADPNPLVAGAGLERLR 122 Query: 133 AAGIEVACGMLEEEAREINIGFLHRMRTGRPWVRMKSAASLDGKTALHNGVSQWITSQAA 192 AAGI V +L + A E+NIGF RM++G+PWVRMK+AASLDGKTALHNG SQWIT+ A Sbjct: 123 AAGIAVTTEVLRDAALEMNIGFFSRMQSGKPWVRMKAAASLDGKTALHNGASQWITAAPA 182 Query: 193 RDDGHIWRARACAIMAGIGTIQKDDAQLTVRAIDTPRQPRRIVVDSKLIVSPEARVIQGG 252 RDDGH+WRARACA++ GIGT++ DD QLTVRA+ TPRQPRRIV+DS+L + +AR++Q Sbjct: 183 RDDGHVWRARACAVLTGIGTVKADDPQLTVRAVATPRQPRRIVIDSRLEIDLQARILQDA 242 Query: 253 NTWVFTATDDREKRAALEAEGAEVILLDNAEGKVDLPGLVRELGQRQINELHVEAGAKLN 312 WV A D +K+AALE+ G EVI L NA GKVDLPGL+RELG+RQINELHVEAG KLN Sbjct: 243 PVWVVCAQADADKQAALESLGHEVICLPNAAGKVDLPGLMRELGRRQINELHVEAGFKLN 302 Query: 313 GALIRAGCVDELLVYLAPALIGDGRNMFELPPLEDLSGKIGIHFHEVKQVGPDLRILARF 372 G+L+R GCVDELL+YLAP+LIGD + +F+LP L LSGK G+ FH+VKQ+GPDLRILAR Sbjct: 303 GSLLREGCVDELLLYLAPSLIGDAQGLFDLPALTSLSGKTGLVFHDVKQIGPDLRILARL 362