BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.4510.p (653 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776993.1| 16S rRNA uridine-516 pseudouridylate synthas... 653 0.0 ref|YP_001100689.1| putative pseudouridine synthase (Uracil hydr... 459 e-127 ref|YP_001354188.1| ribosomal large subunit pseudouridine syntha... 455 e-125 ref|YP_004754093.1| ribosomal large subunit pseudouridine syntha... 448 e-123 ref|ZP_08276235.1| Ribosomal large subunit pseudouridine synthas... 433 e-119 >ref|YP_003776993.1| 16S rRNA uridine-516 pseudouridylate synthase [Herbaspirillum seropedicae SmR1] gb|ADJ65085.1| 16S rRNA uridine-516 pseudouridylate synthase protein [Herbaspirillum seropedicae SmR1] Length = 560 Score = 653 bits (1685), Expect = 0.0, Method: Composition-based stats. Identities = 444/566 (78%), Positives = 474/566 (83%), Gaps = 28/566 (4%) Query: 93 RAKKVVADADTAPAPAPVAESASPAAEAPKVIVTIGEEITAAPVLLDAPTDSARTKPARR 152 +AK V A+ APAPA E PKVIVT+G+E+ A PVLLDAP D R KPARR Sbjct: 18 KAKPVEAEQIAAPAPA----------ELPKVIVTVGDEVVAPPVLLDAPADPNRNKPARR 67 Query: 153 GVRGPRALRNNRAAQRAAEAGQG----EQHHAVAGDEQPLSVDANAPVPVADQAMAESRR 208 GVRGPRALRNNRAAQRAA + +G + + A ++QP Q + Sbjct: 68 GVRGPRALRNNRAAQRAAASAEGGVPGKADNGAAPEQQPRG-----------QFGKGHGQ 116 Query: 209 DGQGQDRNRQQKGKKPFVKGGK-PKAPQLGLRSHDAGDDVFSFVTSDAYDKEDGARSGAR 267 GQ + Q+GKK F K GK PKAPQLGLR+ + DD+FS+VTS+AYD+++ + GAR Sbjct: 117 GGQNAQNGQGQQGKKNFDKNGKKPKAPQLGLRAAEPVDDIFSYVTSEAYDRDENPKGGAR 176 Query: 268 GTHQMRGKNGRRDLTAEDDAPKLHKVLADAGLGSRRDMEELIVAGRVSVNGEPAHIGQRI 327 HQMRGKNGRRDLTAEDDAPKLHKVLADAGLGSRRDMEELIVAGRVSVNGEPAHIGQRI Sbjct: 177 QPHQMRGKNGRRDLTAEDDAPKLHKVLADAGLGSRRDMEELIVAGRVSVNGEPAHIGQRI 236 Query: 328 LPTDAVRINGKLIQRKVSKRPPRVLVYHKPSGEIVSHADPEGRSSVFDRLPTMKAGKWLA 387 LPTDAVRINGKLIQRKVSKRPPRVLVYHKP+GEIVSHADPEGR+SVFDRLPTMKAGKWLA Sbjct: 237 LPTDAVRINGKLIQRKVSKRPPRVLVYHKPAGEIVSHADPEGRNSVFDRLPTMKAGKWLA 296 Query: 388 VGRLDFNTEGLLLFTTSGDLANRLMHPRYNIEREYAVRTLGELEEGMRQKLLSGVELDDG 447 VGRLD+NTEGLLLFTTSGDLANRLMHPRYNIEREYAVRTLGELEEGMRQKLLSGVELDDG Sbjct: 297 VGRLDYNTEGLLLFTTSGDLANRLMHPRYNIEREYAVRTLGELEEGMRQKLLSGVELDDG 356 Query: 448 PAQFSRIADGGGEGVNKWYRVTIGEGRNREVRRMFEAVGLTVSRLIRTRYGAMTLPQTLK 507 PAQFSRIADGGGEGVNKWYRVTIGEGRNREVRRMFEAVGLTVSRLIRTRYGAMTLPQTL+ Sbjct: 357 PAQFSRIADGGGEGVNKWYRVTIGEGRNREVRRMFEAVGLTVSRLIRTRYGAMTLPQTLR 416 Query: 508 RGRWEELEENAVRNLMAACGLEKQAGEAKSGNGGNAGQASRGQGNGPRGNAMQNKGPQKG 567 RGRWEELEENAVRNLMAACGLEKQAGE KSGNGG+AG+ +G GNGPRGNAMQNKGPQKG Sbjct: 417 RGRWEELEENAVRNLMAACGLEKQAGEGKSGNGGHAGKG-QGNGNGPRGNAMQNKGPQKG 475 Query: 568 RQGGNFGQGGNGGNGGNYGNGGGYGGGGGNKGGQPKSRQPDPLQTALGFPDAGNQRRGNR 627 R G QGGN GN G G G GGGNKGGQPKSRQPDPLQTALGFPDAG QRR NR Sbjct: 476 RGGNYGNQGGNYGNQGGNYGNQGGGYGGGNKGGQPKSRQPDPLQTALGFPDAG-QRRNNR 534 Query: 628 PQRGGNSAPNFMLGGLPGMNRRRGGR 653 PQRGGNSAPNFMLGGLPGMNRRRGGR Sbjct: 535 PQRGGNSAPNFMLGGLPGMNRRRGGR 560 >ref|YP_001100689.1| putative pseudouridine synthase (Uracil hydrolyase) [Herminiimonas arsenicoxydans] emb|CAL62568.1| Pseudouridine synthase [Herminiimonas arsenicoxydans] Length = 538 Score = 459 bits (1180), Expect = e-127, Method: Composition-based stats. Identities = 311/494 (62%), Positives = 350/494 (70%), Gaps = 29/494 (5%) Query: 148 KPARRGVRGPRALRNNRAAQRAAEAGQGEQHHAVAGDEQPLSVDANAPVPVADQAMAESR 207 KP +RG+RGPR LR R A R+ G +H ++ + V+ A VP A E R Sbjct: 42 KPVKRGLRGPRTLRRARNAPRS-----GPANHDTPEEQNAVVVETQA-VP----ASGEVR 91 Query: 208 RDGQGQDRNRQQKGKKPFVKGGKP--KAPQLGLRSHDAG---DDVFSFVTSDAYDKEDGA 262 R+ + RQ K P GK P G + H G DDVFSFVTS+A+D Sbjct: 92 RERNPRRDERQPGTKGPQKSSGKSGGAGPNRGSKPHSRGGDADDVFSFVTSEAFDTLSVD 151 Query: 263 RSGARGTHQMRGKNGRRDLTAEDDAPKLHKVLADAGLGSRRDMEELIVAGRVSVNGEPAH 322 A G + K+ RRDLTA+DDAPKLHKVLA+AGLGSRRDMEELI+AGRVSVNGEPAH Sbjct: 152 DDKAGGKRRPEQKSVRRDLTADDDAPKLHKVLAEAGLGSRRDMEELIIAGRVSVNGEPAH 211 Query: 323 IGQRILPTDAVRINGKLIQRKVSKRPPRVLVYHKPSGEIVSHADPEGRSSVFDRLPTMKA 382 IGQRILP D VRINGKLIQRKVS +PPRVLVYHKP+GEIVS DPEGR SVF+RLPTMKA Sbjct: 212 IGQRILPADQVRINGKLIQRKVSNKPPRVLVYHKPAGEIVSTNDPEGRPSVFERLPTMKA 271 Query: 383 GKWLAVGRLDFNTEGLLLFTTSGDLANRLMHPRYNIEREYAVRTLGELEEGMRQKLLSGV 442 KWLAVGRLDFNTEGLLLFTTSGDLANRLMHPRY I+REYAVRTLGELEEGMRQKLL+GV Sbjct: 272 AKWLAVGRLDFNTEGLLLFTTSGDLANRLMHPRYGIDREYAVRTLGELEEGMRQKLLAGV 331 Query: 443 ELDDGPAQFSRIADGGGEGVNKWYRVTIGEGRNREVRRMFEAVGLTVSRLIRTRYGAMTL 502 EL+DG AQFS+IADGGGEGVNKWYRVTIGEGRNREVRRMFEA+GLTVSRLIRTRYG +TL Sbjct: 332 ELEDGLAQFSKIADGGGEGVNKWYRVTIGEGRNREVRRMFEAIGLTVSRLIRTRYGTLTL 391 Query: 503 PQTLKRGRWEELEENAVRNLMAACGLEKQAGEAKSGNGGNAGQASRGQGNGPRGNAMQNK 562 P+ LKRGRWEE+EE+AVR+L+A GLEK KS +G G+ N P N+ Sbjct: 392 PKNLKRGRWEEMEEHAVRDLLAMSGLEK-----KSVDGAPKGR------NSPADRQNGNR 440 Query: 563 GPQKGRQGG---NFGQGGNGGNGGNYGNGGGYGGGGGNKGGQPKSRQPDPLQTALGFPDA 619 P+ G + Q GN G G G GG GQP+SRQPDPLQT+LGFP Sbjct: 441 APRVDNGMGLPRSPSQWGNLGGQGRPQGQNGKPAGGRQGQGQPRSRQPDPLQTSLGFPGM 500 Query: 620 GNQRRGNRPQRGGN 633 G RR N P RG N Sbjct: 501 GQPRRSNGPNRGPN 514 >ref|YP_001354188.1| ribosomal large subunit pseudouridine synthase B [Janthinobacterium sp. Marseille] gb|ABR89575.1| ribosomal large subunit pseudouridine synthase B [Janthinobacterium sp. Marseille] Length = 546 Score = 455 bits (1170), Expect = e-125, Method: Composition-based stats. Identities = 312/492 (63%), Positives = 345/492 (70%), Gaps = 16/492 (3%) Query: 140 APTDSARTKPARRGVRGPRALRNNRAAQR-AAEAGQGEQHHAVAGDEQPLSVDANAPVP- 197 A + A KPA+RG+RGPR LR R R A E + A E P +AP Sbjct: 30 AAQEGAGAKPAKRGLRGPRTLRRARNTPREATEPAVVKVDGAEGAQEMPQGEAGSAPADG 89 Query: 198 VADQAMAESRRDGQGQDRNRQQKGKKPFVKGGKPKA--PQLGLRSH---DAGDDVFSFVT 252 A + + R G+ Q + KG GKP PQ G + H D DDVFSFVT Sbjct: 90 EARRERTNNNRRGERQPGAKGAKGATRPQGRGKPNGAGPQRGGKPHGKADNADDVFSFVT 149 Query: 253 SDAYDKEDGARSGARGTHQMRGKNGRRDLTAEDDAPKLHKVLADAGLGSRRDMEELIVAG 312 SD +D A A G + K RRDLTA+DDAPKLHKVLA+AGLGSRRDMEELI+AG Sbjct: 150 SDDFDSL-AAEDSAGGKRRHEQKTVRRDLTADDDAPKLHKVLAEAGLGSRRDMEELIIAG 208 Query: 313 RVSVNGEPAHIGQRILPTDAVRINGKLIQRKVSKRPPRVLVYHKPSGEIVSHADPEGRSS 372 RVSVNGEPAHIGQRILPTD VRINGKLIQRKVSK+PPRVLVYHKP+GEIVS DPEGR S Sbjct: 209 RVSVNGEPAHIGQRILPTDQVRINGKLIQRKVSKKPPRVLVYHKPAGEIVSTNDPEGRPS 268 Query: 373 VFDRLPTMKAGKWLAVGRLDFNTEGLLLFTTSGDLANRLMHPRYNIEREYAVRTLGELEE 432 VFDRLPTMKA KWLAVGRLDFNTEGLLLFTTSGDLANRLMHPRY I+REYAVRTLGELEE Sbjct: 269 VFDRLPTMKAAKWLAVGRLDFNTEGLLLFTTSGDLANRLMHPRYGIDREYAVRTLGELEE 328 Query: 433 GMRQKLLSGVELDDGPAQFSRIADGGGEGVNKWYRVTIGEGRNREVRRMFEAVGLTVSRL 492 GMRQKLL+GVEL+DG AQFS+IADGGGEGVNKWYRVTIGEGRNREVRRMFEA+GLTVSRL Sbjct: 329 GMRQKLLAGVELEDGLAQFSKIADGGGEGVNKWYRVTIGEGRNREVRRMFEAIGLTVSRL 388 Query: 493 IRTRYGAMTLPQTLKRGRWEELEENAVRNLMAACGLEKQAGEAKSGNGGNAGQASRGQGN 552 IRTRYG +TLP+ LKRGRWEE+EE+AVR+L+A GL+K GEA N G A R GN Sbjct: 389 IRTRYGLLTLPKNLKRGRWEEMEEHAVRDLLALSGLDKNTGEAGPANKGRAAGGDRVNGN 448 Query: 553 GPRGNAMQNKGPQKGRQGGNFGQGGNGGNGGNYGNGGGYGGGGGNKGGQPKSRQPDPLQT 612 P+ Q N G G G G G N+ GQ +SRQPDPLQT Sbjct: 449 RAPRVDNGLGQPRSPSQWQNTGTG--------QGRSQGQNPGKPNRQGQQRSRQPDPLQT 500 Query: 613 ALGFPDAGNQRR 624 +LGFP G RR Sbjct: 501 SLGFPGMGQPRR 512 >ref|YP_004754093.1| ribosomal large subunit pseudouridine synthase B [Collimonas fungivorans Ter331] gb|AEK63270.1| Ribosomal large subunit pseudouridine synthase B [Collimonas fungivorans Ter331] Length = 668 Score = 448 bits (1152), Expect = e-123, Method: Composition-based stats. Identities = 366/653 (56%), Positives = 413/653 (63%), Gaps = 52/653 (7%) Query: 1 MKPSSSNDDQQIDLLGAAADNATAVKPARKRVKKAAAEDVATEVAPIEKPAKAPAKPRAK 60 M P SSND +DL A D A KP ++V A V A + Sbjct: 1 MNPPSSNDAPVVDLT-ATTDPKPAKKPRARKVAADAPIAADAAVPAAAAAEPAKPARAPR 59 Query: 61 KVAAEAPAETVAPAPVAAEVAADAPAPKKRAPRAKKVVADADTAPAPAPVAESASPAAEA 120 K A A A A PA K APR K P+ E AA A Sbjct: 60 KKAVAAAESGAAET--AVAAETATPAKPKAAPRKK-----VQVVVEPSTAVEFVVEAAPA 112 Query: 121 PKVIVTIGEEITAAPVLLDAPTDSARTKPARRGVRGPRALRNNRAAQRAAEAGQGEQHHA 180 V V +EI+ AP AR +PA+RGVRGPRALR+NRAAQRA E+ A Sbjct: 113 VVVPVVANQEISEAP---------ARERPAKRGVRGPRALRSNRAAQRAQESAAAASSAA 163 Query: 181 VAG-----DEQPLSVDANAPVPVADQAMAESR-----------RDGQGQDRNRQQKGKKP 224 AG + QP A P D A E R R+G+ R RQ KGKKP Sbjct: 164 EAGNAAVTEGQPSVAQVQA--PAGDPAAGEPRQQRGDRNNGAGRNGERNSRERQPKGKKP 221 Query: 225 FVKGGKPKAPQLGLRSHDAG--DDVFSFVTSDAYDKEDGARSGARGTHQMRGKNGRRDLT 282 + GKP G + G D+ FSFVTS+++D A A Q K+ RRDLT Sbjct: 222 LAQNGKPGQGPRGGKPSRGGDADEAFSFVTSESFDTLVTAEDAAGRQAQ---KSVRRDLT 278 Query: 283 AEDDAPKLHKVLADAGLGSRRDMEELIVAGRVSVNGEPAHIGQRILPTDAVRINGKLIQR 342 AEDDAPKLHKVLAD GLGSRRDMEELI+AGRVSVNGEPAHIGQRILPTD VRINGKL+QR Sbjct: 279 AEDDAPKLHKVLADVGLGSRRDMEELIIAGRVSVNGEPAHIGQRILPTDQVRINGKLLQR 338 Query: 343 KVSKRPPRVLVYHKPSGEIVSHADPEGRSSVFDRLPTMKAGKWLAVGRLDFNTEGLLLFT 402 KVSKRPPRVLVYHKP+GEIVSH DP+GR SVFDRLP MKA KWLAVGRLDFNTEGLLLFT Sbjct: 339 KVSKRPPRVLVYHKPAGEIVSHNDPDGRPSVFDRLPNMKAAKWLAVGRLDFNTEGLLLFT 398 Query: 403 TSGDLANRLMHPRYNIEREYAVRTLGELEEGMRQKLLSGVELDDGPAQFSRIADGGGEGV 462 TSGDLANRLMHPRY I+REYAVRTLGELE+GMRQKLL+GVEL+DG AQF++IADGGGEG+ Sbjct: 399 TSGDLANRLMHPRYGIDREYAVRTLGELEQGMRQKLLAGVELEDGVAQFTKIADGGGEGI 458 Query: 463 NKWYRVTIGEGRNREVRRMFEAVGLTVSRLIRTRYGAMTLPQTLKRGRWEELEENAVRNL 522 NKWYRV IGEGRNREVRRMFEA+GLTVSRLIRTRYGAMTLP+ LKRGRWEEL+ENAVR++ Sbjct: 459 NKWYRVVIGEGRNREVRRMFEAIGLTVSRLIRTRYGAMTLPRGLKRGRWEELDENAVRDM 518 Query: 523 MAACGLEKQAGEAKSGNGGNAGQASRG-QGNGPRGNAMQNKGPQK----------GRQGG 571 +AA GL+K A +G G ++ Q NG R ++ G+ G Sbjct: 519 LAAHGLDKPAAGQGAGGGKGRPDFNKDRQPNGNRADSAPQGPGGGGYRGGDQGFGGQPRG 578 Query: 572 NFGQGGNGGNGGNYGNGGGYGGGGGNKGGQPKSRQPDPLQTALGFPDAGNQRR 624 NFG G GN G GG GG+ G P+SRQPDPLQTALGFPDAG QRR Sbjct: 579 NFG-GQPRGNQGRGPGGGQGRPQGGSGGQPPRSRQPDPLQTALGFPDAGQQRR 630 >ref|ZP_08276235.1| Ribosomal large subunit pseudouridine synthase B [Oxalobacteraceae bacterium IMCC9480] gb|EGF30293.1| Ribosomal large subunit pseudouridine synthase B [Oxalobacteraceae bacterium IMCC9480] Length = 621 Score = 433 bits (1114), Expect = e-119, Method: Composition-based stats. Identities = 320/572 (55%), Positives = 363/572 (63%), Gaps = 47/572 (8%) Query: 81 AADAPAPKKRAPRAKKVVADADTAPAPAPVAESASPAAEAPKVIVTIGEEITAAPVLLDA 140 +A+ P+KR PRAK V A A +A AS AP + ++ + AAP Sbjct: 19 SAEPKVPRKRTPRAKPPVQAVAEASAAPAIATVASGEPAAPSMSLSSTPDAAAAP----- 73 Query: 141 PTDSARTKPARRGVRGPRALRNNR-AAQRAAEAGQGEQHHAVAGDEQPLSVDANAPVPVA 199 RR VRGPR LR R +R A A G A G P A V Sbjct: 74 ----------RRNVRGPRNLRRTRDPVERNAVAQDGTAVVAQEGAPDPAQ---PAQVRPP 120 Query: 200 DQAMAESRRDGQGQDRNRQQKG-KKPFVKGGKPKAPQLGLRSHDAGDDVFSFVTSDAYDK 258 Q R +DR + Q G +K K A + R DA D VFSFVTS A+D Sbjct: 121 RQHAPREARPRSNEDRPKGQGGAQKSRQKQPAGNAARNAPRGTDA-DSVFSFVTSAAFDD 179 Query: 259 EDGARSGARGTHQMRGKNGRRDLTAEDDAPKLHKVLADAGLGSRRDMEELIVAGRVSVNG 318 G G K RRDLTA+DDAPKLHKVLA+AGLGSRRDMEELI++GRVSVNG Sbjct: 180 STGDEPG--NGRSPAAKVVRRDLTADDDAPKLHKVLAEAGLGSRRDMEELIISGRVSVNG 237 Query: 319 EPAHIGQRILPTDAVRINGKLIQRKVSKRPPRVLVYHKPSGEIVSHADPEGRSSVFDRLP 378 EPAHIGQRIL D VRINGKLIQR+VSK+PPRVLVYHKP+GEIVSH DP+GR SVF+RLP Sbjct: 238 EPAHIGQRILAQDQVRINGKLIQRRVSKKPPRVLVYHKPAGEIVSHDDPDGRPSVFERLP 297 Query: 379 TMKAGKWLAVGRLDFNTEGLLLFTTSGDLANRLMHPRYNIEREYAVRTLGELEEGMRQKL 438 MKAGKWLAVGRLDFNTEGLLLFTTSGDLANRLMHPRYNI+REYAVRTLGELEEGMRQKL Sbjct: 298 NMKAGKWLAVGRLDFNTEGLLLFTTSGDLANRLMHPRYNIDREYAVRTLGELEEGMRQKL 357 Query: 439 LSGVELDDGPAQFSRIADGGGEGVNKWYRVTIGEGRNREVRRMFEAVGLTVSRLIRTRYG 498 L+GVELDDG AQFSR+ADGGGEGVNKWYRVTIGEGRNREVRRMFEA+GLTVSRLIRTRYG Sbjct: 358 LAGVELDDGVAQFSRVADGGGEGVNKWYRVTIGEGRNREVRRMFEAIGLTVSRLIRTRYG 417 Query: 499 AMTLPQTLKRGRWEELEENAVRNLMAACGLEKQAGEAKSGNGGNAGQASRGQGNGPR--- 555 AM LP LKRGRWEE++E++VR+L+ GLEK G+++ G + S G NG R Sbjct: 418 AMVLPPNLKRGRWEEMDEHSVRDLLKISGLEKTVGKSEPSRGRSDEHDSEGGVNGNRIER 477 Query: 556 ---------GNAMQNKGPQKGRQGGNFGQGGNGGNGGNYGNGGGYGGGG----------- 595 N + P+ G+ G G G GG G G G G Sbjct: 478 APATARHGAPNGNRANAPEPGQWQGKGRSGPARGPGGFAGQGQPRGPGAYPAQGQGGQGQ 537 Query: 596 -GNKGGQPKSRQPDPLQTALGFPDAGNQRRGN 626 + +SRQPDP+QTALGFP G RR N Sbjct: 538 GRGAPAKARSRQPDPMQTALGFPGMGQPRRSN 569