BLASTP 2.2.17 [Aug-26-2007]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for composition-based statistics:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= 0001.4323.p         (193 letters)

Database: All non-redundant GenBank CDS
translations+PDB+SwissProt+PIR+PRF excluding environmental samples
from WGS projects 
           15,459,386 sequences; 5,307,515,862 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

ref|YP_003776838.1| dihydrofolate reductase oxidoreductase [Herb...   278   3e-73
ref|YP_001352882.1| dihydrofolate reductase [Janthinobacterium s...   258   3e-67
ref|YP_001099361.1| dihydrofolate reductase [Herminiimonas arsen...   255   3e-66
ref|YP_004752083.1| dihydrofolate reductase [Collimonas fungivor...   233   9e-60
ref|ZP_08274137.1| Dihydrofolate reductase [Oxalobacteraceae bac...   230   9e-59

>ref|YP_003776838.1| dihydrofolate reductase oxidoreductase [Herbaspirillum seropedicae
           SmR1]
 gb|ADJ64930.1| dihydrofolate reductase oxidoreductase protein [Herbaspirillum
           seropedicae SmR1]
          Length = 164

 Score =  278 bits (711), Expect = 3e-73,   Method: Composition-based stats.
 Identities = 142/164 (86%), Positives = 149/164 (90%)

Query: 30  MTTASGSLTIVVATDLNNGIGIRNTLPWHLPEDLAHFKRTTSGHAILMGRKTFESIGRPL 89
           MTT+SG LT++VATDLNNGIGI NTLPW LPEDLAHFKRTTSGHAILMGRKTF+SIGRPL
Sbjct: 1   MTTSSGQLTLIVATDLNNGIGINNTLPWRLPEDLAHFKRTTSGHAILMGRKTFDSIGRPL 60

Query: 90  PNRRNIVITRNTEWQHAGVETAASLQDAAALAQGAPAFIIGGAQIYAEALPLVDRLIITR 149
           PNRRNIVITRN  WQH GVETA SLQ+AAAL  GAPAFIIGGAQIYAEALPL DRLIITR
Sbjct: 61  PNRRNIVITRNAGWQHDGVETAGSLQEAAALCAGAPAFIIGGAQIYAEALPLADRLIITR 120

Query: 150 INQAFDCDAFFPALDPLLWQETAREDHRSETSGLDYAFVTYERR 193
           I Q FDCDAFFPALD  +WQETARE+H SETSGLDYAFVTYERR
Sbjct: 121 IAQTFDCDAFFPALDQQVWQETAREEHHSETSGLDYAFVTYERR 164


>ref|YP_001352882.1| dihydrofolate reductase [Janthinobacterium sp. Marseille]
 gb|ABR88509.1| dihydrofolate reductase [Janthinobacterium sp. Marseille]
          Length = 162

 Score =  258 bits (659), Expect = 3e-67,   Method: Composition-based stats.
 Identities = 120/156 (76%), Positives = 132/156 (84%)

Query: 37  LTIVVATDLNNGIGIRNTLPWHLPEDLAHFKRTTSGHAILMGRKTFESIGRPLPNRRNIV 96
           LTIVVATD NNGIGI NTLPWHLPEDLAHFKRTTSGH I+MGRKTF+SIGRPLPNRRNIV
Sbjct: 5   LTIVVATDSNNGIGINNTLPWHLPEDLAHFKRTTSGHPIIMGRKTFDSIGRPLPNRRNIV 64

Query: 97  ITRNTEWQHAGVETAASLQDAAALAQGAPAFIIGGAQIYAEALPLVDRLIITRINQAFDC 156
           ITRN EWQHAGVE   SL  A AL     AFIIGGAQIY + +  VDRLI+T+I+++FDC
Sbjct: 65  ITRNAEWQHAGVEAVTSLDSAKALVGDNQAFIIGGAQIYTDTVGQVDRLIVTKIDKSFDC 124

Query: 157 DAFFPALDPLLWQETAREDHRSETSGLDYAFVTYER 192
           DAFFPA+DP LWQETARE H SE +G DYA+VTYER
Sbjct: 125 DAFFPAIDPKLWQETAREQHHSEANGYDYAYVTYER 160


>ref|YP_001099361.1| dihydrofolate reductase [Herminiimonas arsenicoxydans]
 emb|CAL61234.1| dihydrofolate reductase [Herminiimonas arsenicoxydans]
          Length = 162

 Score =  255 bits (651), Expect = 3e-66,   Method: Composition-based stats.
 Identities = 118/156 (75%), Positives = 133/156 (85%)

Query: 37  LTIVVATDLNNGIGIRNTLPWHLPEDLAHFKRTTSGHAILMGRKTFESIGRPLPNRRNIV 96
           LTIVVA D NNGIGI NTLPWHLPEDLAHFKRTTSGH I+MGRKTF+SIGRPLPNRRNIV
Sbjct: 5   LTIVVAIDTNNGIGINNTLPWHLPEDLAHFKRTTSGHPIIMGRKTFDSIGRPLPNRRNIV 64

Query: 97  ITRNTEWQHAGVETAASLQDAAALAQGAPAFIIGGAQIYAEALPLVDRLIITRINQAFDC 156
           ITRNTEWQHAGVET  SL  A AL  G PAFIIGG QI+A+ L   +RLI+TRI++ FDC
Sbjct: 65  ITRNTEWQHAGVETVTSLAAAKALVDGTPAFIIGGGQIFADTLADSNRLIVTRIDKTFDC 124

Query: 157 DAFFPALDPLLWQETAREDHRSETSGLDYAFVTYER 192
           DAFFPA+DP  WQETARE+H SE +G D+A++TY+R
Sbjct: 125 DAFFPAIDPRQWQETAREEHHSEVNGFDFAYITYDR 160


>ref|YP_004752083.1| dihydrofolate reductase [Collimonas fungivorans Ter331]
 gb|AEK61260.1| Dihydrofolate reductase [Collimonas fungivorans Ter331]
          Length = 170

 Score =  233 bits (595), Expect = 9e-60,   Method: Composition-based stats.
 Identities = 113/156 (72%), Positives = 124/156 (79%)

Query: 37  LTIVVATDLNNGIGIRNTLPWHLPEDLAHFKRTTSGHAILMGRKTFESIGRPLPNRRNIV 96
           LTI+VATD  NGIGIRNTLPWHLPEDLAHFKRTTSGH I+MGRKTFESIGRPLP RRNIV
Sbjct: 5   LTIIVATDARNGIGIRNTLPWHLPEDLAHFKRTTSGHPIIMGRKTFESIGRPLPQRRNIV 64

Query: 97  ITRNTEWQHAGVETAASLQDAAALAQGAPAFIIGGAQIYAEALPLVDRLIITRINQAFDC 156
           ITRN  W+H GVE+A SL  AA +   A AFIIGGA+IYA A  L  RLI+T I  +FDC
Sbjct: 65  ITRNPGWRHDGVESAPSLAAAAVMVGDAEAFIIGGAEIYAAAQDLTQRLIVTEIQHSFDC 124

Query: 157 DAFFPALDPLLWQETAREDHRSETSGLDYAFVTYER 192
           DAFFPA DP  WQE +RE H SE +G DYAFV Y+R
Sbjct: 125 DAFFPARDPSQWQEISRETHHSEANGFDYAFVVYQR 160


>ref|ZP_08274137.1| Dihydrofolate reductase [Oxalobacteraceae bacterium IMCC9480]
 gb|EGF32394.1| Dihydrofolate reductase [Oxalobacteraceae bacterium IMCC9480]
          Length = 162

 Score =  230 bits (586), Expect = 9e-59,   Method: Composition-based stats.
 Identities = 108/158 (68%), Positives = 128/158 (81%)

Query: 36  SLTIVVATDLNNGIGIRNTLPWHLPEDLAHFKRTTSGHAILMGRKTFESIGRPLPNRRNI 95
           +LT++VA D   GIGIRNT+PW LPEDLAHFKRTT+GH ILMGRKTFESIGRPLPNRRNI
Sbjct: 3   TLTLIVAIDNAGGIGIRNTMPWKLPEDLAHFKRTTTGHPILMGRKTFESIGRPLPNRRNI 62

Query: 96  VITRNTEWQHAGVETAASLQDAAALAQGAPAFIIGGAQIYAEALPLVDRLIITRINQAFD 155
           VI+RN +W+H GVET ASLQ A  L + A  F+IGGA+IY  ALPL DRLI+T I Q F+
Sbjct: 63  VISRNPDWRHEGVETVASLQAALDLPEAAEVFVIGGAEIYRLALPLADRLIVTEIKQRFE 122

Query: 156 CDAFFPALDPLLWQETAREDHRSETSGLDYAFVTYERR 193
           CDAFFP +DP  W  TARE H+S ++G D+AFVTY+R+
Sbjct: 123 CDAFFPTIDPAEWIATAREPHQSISNGFDFAFVTYQRQ 160