BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.4189.p (362 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776719.1| malate/L-lactate dehydrogenase [Herbaspirill... 640 0.0 ref|YP_999254.1| malate/L-lactate dehydrogenase [Verminephrobact... 542 e-152 ref|YP_004349131.1| malate/L-lactate dehydrogenase [Burkholderia... 440 e-121 ref|YP_001858614.1| malate/L-lactate dehydrogenase [Burkholderia... 432 e-119 ref|YP_004155642.1| malate/L-lactate dehydrogenase [Variovorax p... 416 e-114 >ref|YP_003776719.1| malate/L-lactate dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ64811.1| malate/L-lactate dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 357 Score = 640 bits (1650), Expect = 0.0, Method: Composition-based stats. Identities = 342/353 (96%), Positives = 350/353 (99%) Query: 9 SMAMPERFSADALRQFASTLLQRAGLEADKADSVAATLVDGDLLGHDTHGLALLAPYVKE 68 +MA PERFSADALRQFA+TLLQ+AGLEADKADSVAATLVDGDLLGHDTHGLALLAPYVKE Sbjct: 4 AMAAPERFSADALRQFATTLLQKAGLEADKADSVAATLVDGDLLGHDTHGLALLAPYVKE 63 Query: 69 LEKGTMTRTGEPEVLSERAAALAWDGRRLPGPWLVHRGIDALIPKARDYGTASLTIHHSH 128 LEKG M ++G+PEVLSERAAALAWDGRRLPGPWLVH+GIDALIPKARDYGTASLTIHHSH Sbjct: 64 LEKGAMAKSGQPEVLSERAAALAWDGRRLPGPWLVHQGIDALIPKARDYGTASLTIHHSH 123 Query: 129 HIACLAAYLLRATQEGFMMILASSDPAVQSVAPFGGTQAVFTPNPIAAGIPTSGTPFLVD 188 HIACLAAYLLRATQEGFMMILASSDPAVQSVAPFGGTQAVFTPNPIAAGIPTSGTPFLVD Sbjct: 124 HIACLAAYLLRATQEGFMMILASSDPAVQSVAPFGGTQAVFTPNPIAAGIPTSGTPFLVD 183 Query: 189 ISASITTNGMSNRLHKAGKQFEEEWLIDGAGHPSRDPAVLSATPPGTILPLGGLSAGHKG 248 ISASITTNGMSNRLHKAGKQFEEEWLIDGAGHPSRDPAVLSATPPGTILPLGGLSAGHKG Sbjct: 184 ISASITTNGMSNRLHKAGKQFEEEWLIDGAGHPSRDPAVLSATPPGTILPLGGLSAGHKG 243 Query: 249 FGLAVLIEALTGGLSGFGRADPAAGWGATVFMSLYDPSAFGGEQDFKRQMDHIAQACRSN 308 FGLAVLIEALTGGLSGFGRADPAAGWGATVFMSLYDPSAFGGEQDFKRQMDHIAQACR+N Sbjct: 244 FGLAVLIEALTGGLSGFGRADPAAGWGATVFMSLYDPSAFGGEQDFKRQMDHIAQACRAN 303 Query: 309 PPRPGVGQVRMPGDRGMQRRAEQLAQGVTLHPTIAPMLREAGAAYDLEFPATL 361 PPRPGVGQVRMPGDRGMQRRAEQLAQGVTLHPTIAPMLREAGAAYDLEFPATL Sbjct: 304 PPRPGVGQVRMPGDRGMQRRAEQLAQGVTLHPTIAPMLREAGAAYDLEFPATL 356 >ref|YP_999254.1| malate/L-lactate dehydrogenase [Verminephrobacter eiseniae EF01-2] gb|ABM60236.1| Malate/L-lactate dehydrogenase [Verminephrobacter eiseniae EF01-2] Length = 354 Score = 542 bits (1397), Expect = e-152, Method: Composition-based stats. Identities = 285/350 (81%), Positives = 316/350 (90%) Query: 10 MAMPERFSADALRQFASTLLQRAGLEADKADSVAATLVDGDLLGHDTHGLALLAPYVKEL 69 MA PERFSA LRQF++ LLQ+AGL AD+VA TLVDGDLLGHDTHGLALL PYV+E+ Sbjct: 1 MAAPERFSAAELRQFSTQLLQKAGLPLAPADAVARTLVDGDLLGHDTHGLALLVPYVREV 60 Query: 70 EKGTMTRTGEPEVLSERAAALAWDGRRLPGPWLVHRGIDALIPKARDYGTASLTIHHSHH 129 KG MT +GEP+V+S+R AAL W+GRRLPGPWLVH+GIDALI +AR+ GTA+L IHHSHH Sbjct: 61 SKGAMTTSGEPDVVSDRPAALVWNGRRLPGPWLVHKGIDALIARARELGTAALVIHHSHH 120 Query: 130 IACLAAYLLRATQEGFMMILASSDPAVQSVAPFGGTQAVFTPNPIAAGIPTSGTPFLVDI 189 IACLAAYLLRAT+EGF+M+L+SSDPAVQSVAPFGGT+AVFTPNPIAAGIPTSGTP LVDI Sbjct: 121 IACLAAYLLRATEEGFLMVLSSSDPAVQSVAPFGGTRAVFTPNPIAAGIPTSGTPLLVDI 180 Query: 190 SASITTNGMSNRLHKAGKQFEEEWLIDGAGHPSRDPAVLSATPPGTILPLGGLSAGHKGF 249 SASITTNGMSNRLHKAG+QFEEEW++D G+PSRDPAVL+A PPG+ILPLGGLSAGHKGF Sbjct: 181 SASITTNGMSNRLHKAGRQFEEEWMLDAQGNPSRDPAVLAADPPGSILPLGGLSAGHKGF 240 Query: 250 GLAVLIEALTGGLSGFGRADPAAGWGATVFMSLYDPSAFGGEQDFKRQMDHIAQACRSNP 309 GLAVLIEALTGGLSGFGRADP GWGATVFMSLYDP+AFGG+ F+RQMDHIA+ACRSNP Sbjct: 241 GLAVLIEALTGGLSGFGRADPPTGWGATVFMSLYDPAAFGGQAAFRRQMDHIAEACRSNP 300 Query: 310 PRPGVGQVRMPGDRGMQRRAEQLAQGVTLHPTIAPMLREAGAAYDLEFPA 359 PRPGVGQVRMPGDRGM RRA+QL QGV LHPTIAPMLREA Y L FPA Sbjct: 301 PRPGVGQVRMPGDRGMARRAQQLEQGVALHPTIAPMLREAAGQYGLAFPA 350 >ref|YP_004349131.1| malate/L-lactate dehydrogenase [Burkholderia gladioli BSR3] gb|AEA63619.1| malate/L-lactate dehydrogenase [Burkholderia gladioli BSR3] Length = 356 Score = 440 bits (1132), Expect = e-121, Method: Composition-based stats. Identities = 233/323 (72%), Positives = 271/323 (83%) Query: 39 ADSVAATLVDGDLLGHDTHGLALLAPYVKELEKGTMTRTGEPEVLSERAAALAWDGRRLP 98 A +VAATLVDGDL+GHDTHGLALLAPYV ELE+GTMTR+GEPEVLS+R A+L WDGRRLP Sbjct: 30 ARAVAATLVDGDLMGHDTHGLALLAPYVGELERGTMTRSGEPEVLSDRGASLLWDGRRLP 89 Query: 99 GPWLVHRGIDALIPKARDYGTASLTIHHSHHIACLAAYLLRATQEGFMMILASSDPAVQS 158 GP LV GI+ L P+AR YG+A+L I SHHIACLA+YL RAT +GFM++L SSDPA S Sbjct: 90 GPSLVLSGIETLAPRARQYGSATLVIRRSHHIACLASYLERATADGFMILLGSSDPATHS 149 Query: 159 VAPFGGTQAVFTPNPIAAGIPTSGTPFLVDISASITTNGMSNRLHKAGKQFEEEWLIDGA 218 VAPFGGT+AVFTPNPIAAGIPTSGTPFL+DISAS+ TNGMS RL +AG+QF+E L+D Sbjct: 150 VAPFGGTRAVFTPNPIAAGIPTSGTPFLIDISASLVTNGMSARLARAGQQFDEPVLLDAE 209 Query: 219 GHPSRDPAVLSATPPGTILPLGGLSAGHKGFGLAVLIEALTGGLSGFGRADPAAGWGATV 278 G+ SRDPAVL+ PPGTILPLGGL GHKGFGLA+LI+ALTGGL+G GRADP GWGATV Sbjct: 210 GNASRDPAVLNTEPPGTILPLGGLPFGHKGFGLALLIDALTGGLAGHGRADPPDGWGATV 269 Query: 279 FMSLYDPSAFGGEQDFKRQMDHIAQACRSNPPRPGVGQVRMPGDRGMQRRAEQLAQGVTL 338 +++L+DPSAFGGE DF+RQMD IA+ACRSNPPRPG +VRMPGDRG+ R+ EQL GV L Sbjct: 270 YLTLHDPSAFGGEADFRRQMDWIAEACRSNPPRPGFSEVRMPGDRGLARKREQLQAGVKL 329 Query: 339 HPTIAPMLREAGAAYDLEFPATL 361 HP IAP L G + L+ PA + Sbjct: 330 HPAIAPALSACGERHGLKLPARI 352 >ref|YP_001858614.1| malate/L-lactate dehydrogenase [Burkholderia phymatum STM815] gb|ACC71568.1| Malate/L-lactate dehydrogenase [Burkholderia phymatum STM815] Length = 354 Score = 432 bits (1110), Expect = e-119, Method: Composition-based stats. Identities = 221/347 (63%), Positives = 267/347 (76%) Query: 15 RFSADALRQFASTLLQRAGLEADKADSVAATLVDGDLLGHDTHGLALLAPYVKELEKGTM 74 R+SAD L+ FA LL R G+E KA ++A TLVDGDL+GHDTHGLALL Y+ E+E G M Sbjct: 6 RYSADELQVFAQRLLVRVGMEEVKALAIARTLVDGDLMGHDTHGLALLPAYIGEIENGAM 65 Query: 75 TRTGEPEVLSERAAALAWDGRRLPGPWLVHRGIDALIPKARDYGTASLTIHHSHHIACLA 134 T +GEPEV+S+R ++ WDGRRLPGPWLV GI+ L P+A+ YGTA+L I +HHIACLA Sbjct: 66 TCSGEPEVVSDRGGSVLWDGRRLPGPWLVLSGIETLAPRAKKYGTATLVIRRNHHIACLA 125 Query: 135 AYLLRATQEGFMMILASSDPAVQSVAPFGGTQAVFTPNPIAAGIPTSGTPFLVDISASIT 194 +YL RAT +G M++L+SSDPA QSVAP GGT++VFTPNPIAAGIPTSGTPFL+DIS+S+ Sbjct: 126 SYLERATADGLMILLSSSDPAGQSVAPHGGTRSVFTPNPIAAGIPTSGTPFLIDISSSMV 185 Query: 195 TNGMSNRLHKAGKQFEEEWLIDGAGHPSRDPAVLSATPPGTILPLGGLSAGHKGFGLAVL 254 T G++ R HKAG+ F+E +D G PS DP VL PPG+ILP+GG++ GHKGFGLA+L Sbjct: 186 TQGLTARRHKAGQHFDEACFLDADGQPSGDPGVLCTDPPGSILPIGGMTGGHKGFGLALL 245 Query: 255 IEALTGGLSGFGRADPAAGWGATVFMSLYDPSAFGGEQDFKRQMDHIAQACRSNPPRPGV 314 IEALTGGL+G GRADP GWGATVF+SLYDP+AFGG F RQMD + ACR NPPRPG Sbjct: 246 IEALTGGLAGHGRADPPDGWGATVFLSLYDPAAFGGLAAFVRQMDWLGDACRDNPPRPGT 305 Query: 315 GQVRMPGDRGMQRRAEQLAQGVTLHPTIAPMLREAGAAYDLEFPATL 361 VRMPGDRG+ + EQL GV LH TIAP L YD+ P+ L Sbjct: 306 AGVRMPGDRGLNLKREQLRDGVALHSTIAPALEACARRYDIPLPSAL 352 >ref|YP_004155642.1| malate/L-lactate dehydrogenase [Variovorax paradoxus EPS] gb|ADU37531.1| Malate/L-lactate dehydrogenase [Variovorax paradoxus EPS] Length = 355 Score = 416 bits (1068), Expect = e-114, Method: Composition-based stats. Identities = 217/346 (62%), Positives = 262/346 (75%) Query: 16 FSADALRQFASTLLQRAGLEADKADSVAATLVDGDLLGHDTHGLALLAPYVKELEKGTMT 75 + ADALR +AS LLQ+AGL A +DSVA TLV+GDLLGHDTHGLALLA YVKE+E G MT Sbjct: 9 YRADALRDYASALLQKAGLAATMSDSVARTLVEGDLLGHDTHGLALLAGYVKEIESGGMT 68 Query: 76 RTGEPEVLSERAAALAWDGRRLPGPWLVHRGIDALIPKARDYGTASLTIHHSHHIACLAA 135 G PEVLS+R AA+ WDG+RLPGPWL+ +G+D L+P+AR+ GTASL I SHHIACLA Sbjct: 69 PDGAPEVLSDRPAAVLWDGKRLPGPWLMDQGMDLLVPRARELGTASLVIRRSHHIACLAV 128 Query: 136 YLLRATQEGFMMILASSDPAVQSVAPFGGTQAVFTPNPIAAGIPTSGTPFLVDISASITT 195 Y+LRA QE +M+LA SDP SVAPFGGTQAVFTPNP+A G P S +VDISASITT Sbjct: 129 YMLRALQEDMLMLLACSDPNAASVAPFGGTQAVFTPNPLAMGFPLSQGGVMVDISASITT 188 Query: 196 NGMSNRLHKAGKQFEEEWLIDGAGHPSRDPAVLSATPPGTILPLGGLSAGHKGFGLAVLI 255 NGMSNR AG+ F EEWLID +G P+ DP VL PPGT+LP+GGLS GHKG+G+A+L+ Sbjct: 189 NGMSNRKRAAGETFAEEWLIDASGKPTNDPEVLFDEPPGTLLPVGGLSHGHKGYGMALLV 248 Query: 256 EALTGGLSGFGRADPAAGWGATVFMSLYDPSAFGGEQDFKRQMDHIAQACRSNPPRPGVG 315 E LT GL+GFGRADP GWGATV ++L+D +AFGG++ F RQMDH+A CR N P Sbjct: 249 ETLTAGLAGFGRADPKEGWGATVHITLHDLNAFGGKEAFLRQMDHVAAQCRDNTPIDAAK 308 Query: 316 QVRMPGDRGMQRRAEQLAQGVTLHPTIAPMLREAGAAYDLEFPATL 361 VR+PG+ G++RR Q GV LHP+IA L+EA + L+ L Sbjct: 309 PVRLPGEGGLKRREAQSKNGVRLHPSIARSLQEAEQRHGLQLAQAL 354