BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.4167.p (381 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_726598.1| 3-isopropylmalate dehydrogenase [Ralstonia eutr... 655 0.0 ref|YP_004685885.1| 3-isopropylmalate dehydrogenase LeuB [Cupria... 655 0.0 ref|YP_004231693.1| tartrate dehydrogenase [Burkholderia sp. CCG... 647 0.0 ref|YP_002007562.1| tartrate dehydrogenase [Cupriavidus taiwanen... 642 0.0 ref|YP_004350838.1| 3-isopropylmalate dehydrogenase [Burkholderi... 641 0.0 >ref|YP_726598.1| 3-isopropylmalate dehydrogenase [Ralstonia eutropha H16] emb|CAJ93230.1| 3-Isopropylmalate dehydrogenase [Ralstonia eutropha H16] Length = 362 Score = 655 bits (1690), Expect = 0.0, Method: Composition-based stats. Identities = 319/362 (88%), Positives = 344/362 (95%) Query: 19 MKTYRIATIPGDGIGKEVIPAGRQLLQALAAARADLAFDFEDFGWGGDYYRQHGVMMPAD 78 MKTYRIATIPGDGIGKEV+PAGR++++ALAAA AD F+FEDF WGGDYYRQHGVMMPAD Sbjct: 1 MKTYRIATIPGDGIGKEVVPAGREVMEALAAAGADFRFEFEDFDWGGDYYRQHGVMMPAD 60 Query: 79 GLDALRDKDAILFGSAGDPHIPDHVTLWGLRLKICQGFDQYANVRPTRILPGIDAPLKRC 138 GLDALRDKDAILFGSAGDPHIPDH+TLWGLRLKICQGFDQYANVRPTRILPGIDAPLKRC Sbjct: 61 GLDALRDKDAILFGSAGDPHIPDHITLWGLRLKICQGFDQYANVRPTRILPGIDAPLKRC 120 Query: 139 RAEDLNWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTRAGVERIMRFAFKLAQSRP 198 AEDLNWVIVRENSEGEY+GVGGRVHQGHPIEAATDVSMMTR GVERI+RFAFKLAQSRP Sbjct: 121 AAEDLNWVIVRENSEGEYSGVGGRVHQGHPIEAATDVSMMTRVGVERILRFAFKLAQSRP 180 Query: 199 RKLLTVVTKSNAQRYAMVMWDEIAVQIAKEFPDVKWDKELVDAATARMVNRPATLDTIVA 258 RKLLTV+TKSNAQR+AMVMWDE+AVQ+A++FPDV WDKELVDAATARMVNRPA+LDTIVA Sbjct: 181 RKLLTVITKSNAQRHAMVMWDEVAVQVARDFPDVTWDKELVDAATARMVNRPASLDTIVA 240 Query: 259 TNLHADILSDLAAALAGSLGIAPTGNIDPECRYPSMFEPIHGSAFDIMGKGLANPVGTFW 318 TNLHADILSDLAAALAGSLGIAPTGNIDPE RYPSMFEPIHGSAFDIMGKGLANPVGTFW Sbjct: 241 TNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHGSAFDIMGKGLANPVGTFW 300 Query: 319 SVVMLLEHLGEHDAAAQVMQAIEAVTADPALHTGDLGGKATTVQVTEAVCSFVAKAARVQ 378 SVVMLLEHLGE++AA +VMQA+EAVTA+PALHTGDLGGKATT +VT AVC +A + + Sbjct: 301 SVVMLLEHLGENEAAQRVMQAVEAVTANPALHTGDLGGKATTAEVTRAVCDLLAAGQQAK 360 Query: 379 QA 380 A Sbjct: 361 AA 362 >ref|YP_004685885.1| 3-isopropylmalate dehydrogenase LeuB [Cupriavidus necator N-1] gb|AEI77404.1| 3-isopropylmalate dehydrogenase LeuB [Cupriavidus necator N-1] Length = 362 Score = 655 bits (1690), Expect = 0.0, Method: Composition-based stats. Identities = 318/362 (87%), Positives = 344/362 (95%) Query: 19 MKTYRIATIPGDGIGKEVIPAGRQLLQALAAARADLAFDFEDFGWGGDYYRQHGVMMPAD 78 MKTYRIATIPGDGIGKEV+PAGR++++ALA+A A F+FEDF WGGDYYRQHGVMMPAD Sbjct: 1 MKTYRIATIPGDGIGKEVVPAGREVMEALASAGAGFRFEFEDFDWGGDYYRQHGVMMPAD 60 Query: 79 GLDALRDKDAILFGSAGDPHIPDHVTLWGLRLKICQGFDQYANVRPTRILPGIDAPLKRC 138 GLDALRDKDAILFGSAGDPHIPDH+TLWGLRLKICQGFDQYANVRPTRILPGIDAPLKRC Sbjct: 61 GLDALRDKDAILFGSAGDPHIPDHITLWGLRLKICQGFDQYANVRPTRILPGIDAPLKRC 120 Query: 139 RAEDLNWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTRAGVERIMRFAFKLAQSRP 198 AEDLNWVIVRENSEGEY+GVGGRVHQGHPIEAATDVSMMTR GVERI+RFAFKLAQSRP Sbjct: 121 AAEDLNWVIVRENSEGEYSGVGGRVHQGHPIEAATDVSMMTRVGVERILRFAFKLAQSRP 180 Query: 199 RKLLTVVTKSNAQRYAMVMWDEIAVQIAKEFPDVKWDKELVDAATARMVNRPATLDTIVA 258 RKLLTV+TKSNAQR+AMVMWDE+AVQ+A+EFPDV WDKELVDAATARMVNRPA+LDTIVA Sbjct: 181 RKLLTVITKSNAQRHAMVMWDEVAVQVAREFPDVTWDKELVDAATARMVNRPASLDTIVA 240 Query: 259 TNLHADILSDLAAALAGSLGIAPTGNIDPECRYPSMFEPIHGSAFDIMGKGLANPVGTFW 318 TNLHADILSDLAAALAGSLGIAPTGNIDPE RYPSMFEPIHGSAFDIMGKGLANPVGTFW Sbjct: 241 TNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHGSAFDIMGKGLANPVGTFW 300 Query: 319 SVVMLLEHLGEHDAAAQVMQAIEAVTADPALHTGDLGGKATTVQVTEAVCSFVAKAARVQ 378 SVVMLLEHLGE++AA +VMQA+EAVTA+PALHTGDLGGKATT +VT+AVC +A + + Sbjct: 301 SVVMLLEHLGENEAAQRVMQAVEAVTANPALHTGDLGGKATTAEVTKAVCDLLAAGKQAK 360 Query: 379 QA 380 A Sbjct: 361 AA 362 >ref|YP_004231693.1| tartrate dehydrogenase [Burkholderia sp. CCGE1001] gb|ADX58633.1| tartrate dehydrogenase [Burkholderia sp. CCGE1001] Length = 364 Score = 647 bits (1669), Expect = 0.0, Method: Composition-based stats. Identities = 311/355 (87%), Positives = 337/355 (94%) Query: 19 MKTYRIATIPGDGIGKEVIPAGRQLLQALAAARADLAFDFEDFGWGGDYYRQHGVMMPAD 78 MKTYRIATIPGDGIGKEV+PAG Q+L+ALA A AF+FE+F WGGDYYR+HGVMMPAD Sbjct: 1 MKTYRIATIPGDGIGKEVVPAGAQVLEALARATKSFAFEFENFDWGGDYYRRHGVMMPAD 60 Query: 79 GLDALRDKDAILFGSAGDPHIPDHVTLWGLRLKICQGFDQYANVRPTRILPGIDAPLKRC 138 GLDALRDKDAILFGSAGDP IPDH+TLWGLRLKICQGFDQYANVRPTRILPGIDAPLKRC Sbjct: 61 GLDALRDKDAILFGSAGDPDIPDHITLWGLRLKICQGFDQYANVRPTRILPGIDAPLKRC 120 Query: 139 RAEDLNWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTRAGVERIMRFAFKLAQSRP 198 + EDLNWVIVRENSEGEY+GVGGRVHQGHPIEAATDVS+MTRAGVERIMRFAF+LAQSRP Sbjct: 121 KPEDLNWVIVRENSEGEYSGVGGRVHQGHPIEAATDVSIMTRAGVERIMRFAFRLAQSRP 180 Query: 199 RKLLTVVTKSNAQRYAMVMWDEIAVQIAKEFPDVKWDKELVDAATARMVNRPATLDTIVA 258 RKLLTV+TKSNAQR+AMVMWDEIA+Q++KEFPDV WDKELVDA+TARM+NRPA+LDTIVA Sbjct: 181 RKLLTVITKSNAQRHAMVMWDEIALQVSKEFPDVTWDKELVDASTARMINRPASLDTIVA 240 Query: 259 TNLHADILSDLAAALAGSLGIAPTGNIDPECRYPSMFEPIHGSAFDIMGKGLANPVGTFW 318 TNLHADILSDLAAALAGSLGIAPTGNIDPE R+PSMFEPIHGSAFDIMGKGLANPVGTFW Sbjct: 241 TNLHADILSDLAAALAGSLGIAPTGNIDPERRFPSMFEPIHGSAFDIMGKGLANPVGTFW 300 Query: 319 SVVMLLEHLGEHDAAAQVMQAIEAVTADPALHTGDLGGKATTVQVTEAVCSFVAK 373 SVVMLLEHLGE DAA +VMQA+EAVTAD +LHTGDLGG ATT QVT AVC+F+ + Sbjct: 301 SVVMLLEHLGEFDAAQRVMQAVEAVTADKSLHTGDLGGTATTAQVTVAVCAFIER 355 >ref|YP_002007562.1| tartrate dehydrogenase [Cupriavidus taiwanensis LMG 19424] emb|CAQ71505.1| tartrate dehydrogenase [Cupriavidus taiwanensis LMG 19424] Length = 361 Score = 642 bits (1655), Expect = 0.0, Method: Composition-based stats. Identities = 317/363 (87%), Positives = 337/363 (92%), Gaps = 2/363 (0%) Query: 19 MKTYRIATIPGDGIGKEVIPAGRQLLQALAAARADLAFDFEDFGWGGDYYRQHGVMMPAD 78 MKTY+IATIPGDGIGKEV+PAGR++++ALAA A F+FE+F WGGDYYRQHGVMMPAD Sbjct: 1 MKTYKIATIPGDGIGKEVVPAGREVMEALAAHGASFRFEFENFDWGGDYYRQHGVMMPAD 60 Query: 79 GLDALRDKDAILFGSAGDPHIPDHVTLWGLRLKICQGFDQYANVRPTRILPGIDAPLKRC 138 GLDALRDKDAILFGSAGD IPDH+TLWGLRLKICQGFDQYANVRPTRILPGID PLKRC Sbjct: 61 GLDALRDKDAILFGSAGDNQIPDHITLWGLRLKICQGFDQYANVRPTRILPGIDGPLKRC 120 Query: 139 RAEDLNWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTRAGVERIMRFAFKLAQSRP 198 EDLNWVIVRENSEGEY+GVGGRVHQGHPIEAATDVSMMTR GVERI+RFAFKLAQSRP Sbjct: 121 APEDLNWVIVRENSEGEYSGVGGRVHQGHPIEAATDVSMMTRVGVERILRFAFKLAQSRP 180 Query: 199 RKLLTVVTKSNAQRYAMVMWDEIAVQIAKEFPDVKWDKELVDAATARMVNRPATLDTIVA 258 RKLLTV+TKSNAQR+AMVMWDE+AVQ+AK+FPDV WDKELVDAATARMVNRPATLDTIVA Sbjct: 181 RKLLTVITKSNAQRHAMVMWDEVAVQVAKDFPDVTWDKELVDAATARMVNRPATLDTIVA 240 Query: 259 TNLHADILSDLAAALAGSLGIAPTGNIDPECRYPSMFEPIHGSAFDIMGKGLANPVGTFW 318 TNLHADILSDLAAALAGSLGIAPTGNIDPE RYPSMFEPIHGSAFDIMGKGLANPVGTFW Sbjct: 241 TNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHGSAFDIMGKGLANPVGTFW 300 Query: 319 SVVMLLEHLGEHDAAAQVMQAIEAVTADPALHTGDLGGKATTVQVTEAVCSFVAKAARVQ 378 SVVMLLEHLGEH AA +VM AIEAVTA+PALHTGDLGGKA TV VT AVC + AA Q Sbjct: 301 SVVMLLEHLGEHAAAQRVMAAIEAVTANPALHTGDLGGKARTVDVTRAVCDLL--AASSQ 358 Query: 379 QAA 381 +AA Sbjct: 359 KAA 361 >ref|YP_004350838.1| 3-isopropylmalate dehydrogenase [Burkholderia gladioli BSR3] gb|AEA65326.1| 3-isopropylmalate dehydrogenase [Burkholderia gladioli BSR3] Length = 361 Score = 641 bits (1654), Expect = 0.0, Method: Composition-based stats. Identities = 317/359 (88%), Positives = 340/359 (94%) Query: 19 MKTYRIATIPGDGIGKEVIPAGRQLLQALAAARADLAFDFEDFGWGGDYYRQHGVMMPAD 78 MKTYRIATIPGDGIGKEVIPAGR++L+ALAAA A FDFEDF WG DYYRQHGVMMPAD Sbjct: 1 MKTYRIATIPGDGIGKEVIPAGRRVLEALAAADAGFRFDFEDFDWGADYYRQHGVMMPAD 60 Query: 79 GLDALRDKDAILFGSAGDPHIPDHVTLWGLRLKICQGFDQYANVRPTRILPGIDAPLKRC 138 GLDALRDKDAILFGSAGDP +PDH+TLWGLRLKICQGFDQYANVRPTRILPGIDAPLKRC Sbjct: 61 GLDALRDKDAILFGSAGDPDVPDHITLWGLRLKICQGFDQYANVRPTRILPGIDAPLKRC 120 Query: 139 RAEDLNWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTRAGVERIMRFAFKLAQSRP 198 DL+WVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTRAGVERIMRFAF+LAQSRP Sbjct: 121 GPGDLDWVIVRENSEGEYAGVGGRVHQGHPIEAATDVSMMTRAGVERIMRFAFRLAQSRP 180 Query: 199 RKLLTVVTKSNAQRYAMVMWDEIAVQIAKEFPDVKWDKELVDAATARMVNRPATLDTIVA 258 RKLLTV+TKSNAQR+AMVMWDEIA Q+A+EFPDVKWDKELVDA+TARM+NRPA+LDTIVA Sbjct: 181 RKLLTVITKSNAQRHAMVMWDEIAAQVAREFPDVKWDKELVDASTARMINRPASLDTIVA 240 Query: 259 TNLHADILSDLAAALAGSLGIAPTGNIDPECRYPSMFEPIHGSAFDIMGKGLANPVGTFW 318 TNLHADILSDLAAALAGSLGIAPTGNIDPE RYPSMFEPIHGSAFDIMGKG+ANP+GTFW Sbjct: 241 TNLHADILSDLAAALAGSLGIAPTGNIDPERRYPSMFEPIHGSAFDIMGKGIANPIGTFW 300 Query: 319 SVVMLLEHLGEHDAAAQVMQAIEAVTADPALHTGDLGGKATTVQVTEAVCSFVAKAARV 377 SVVMLLEHLGE +AAA+VM+A+EAVTA+PALHTGDLGG+A T QVTEAVC+ VA A V Sbjct: 301 SVVMLLEHLGEPEAAARVMRAVEAVTANPALHTGDLGGQARTEQVTEAVCALVAHGAAV 359