BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.4080.p (437 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776678.1| bifunctional folylpolyglutamate synthase/dih... 817 0.0 ref|YP_004752531.1| folylpolyglutamate synthase [Collimonas fung... 686 0.0 ref|YP_001099529.1| bifunctional folylpolyglutamate synthase/dih... 657 0.0 ref|YP_001353851.1| bifunctional folylpolyglutamate synthase / d... 655 0.0 ref|ZP_08273835.1| Dihydrofolate synthase [Oxalobacteraceae bact... 618 e-175 >ref|YP_003776678.1| bifunctional folylpolyglutamate synthase/dihydrofolate synthase [Herbaspirillum seropedicae SmR1] gb|ADJ64770.1| bifunctional folylpolyglutamate synthase/dihydrofolate synthase protein [Herbaspirillum seropedicae SmR1] Length = 437 Score = 817 bits (2111), Expect = 0.0, Method: Composition-based stats. Identities = 415/437 (94%), Positives = 426/437 (97%) Query: 1 MTSQASPTPATLNEWLALLEQRHFKQIDMGLDRVQAVKEKLDIRFDCPVIMVAGTNGKGS 60 MTSQASPTP TLNEWLALLEQRHFKQIDMGL+RV VK+KLDI FDCPVIMVAGTNGKGS Sbjct: 1 MTSQASPTPTTLNEWLALLEQRHFKQIDMGLERVMQVKQKLDIHFDCPVIMVAGTNGKGS 60 Query: 61 TCAMLESILLRAGYRVGLYIKPHFLHFNERARLSGDMASDAQLIAAFEAVEAQRGDISLT 120 TCAMLESILLRAGYRVGLY+KPHFLHFNERARLSGDMASDAQLIAAFEAVEAQRGDISLT Sbjct: 61 TCAMLESILLRAGYRVGLYMKPHFLHFNERARLSGDMASDAQLIAAFEAVEAQRGDISLT 120 Query: 121 YFEFTTLAIMKLLADARQDVVILEVGLGGRLDAVNVIDADVAIVTSIDIDHTEYLGETRE 180 YFEFTTLAIMKLLADARQDVVILEVGLGGRLDAVNVIDADVAIVTSIDIDHTEYLGETRE Sbjct: 121 YFEFTTLAIMKLLADARQDVVILEVGLGGRLDAVNVIDADVAIVTSIDIDHTEYLGETRE 180 Query: 181 EIGFEKAGIFRPGKVAVCGDPVPPKSLIAHAEKIGADLWLMGRDFNYQGDKQQWAYGGRG 240 EIGFEKAGIFRPGKVAVCGDP+PPKSLIAHAEKIGADLWLMGRDFNYQGDKQQWAYGGRG Sbjct: 181 EIGFEKAGIFRPGKVAVCGDPLPPKSLIAHAEKIGADLWLMGRDFNYQGDKQQWAYGGRG 240 Query: 241 MRRNSLAYPSLRGANQILNASAALAALEALREVLPVGAQEVRTGLATVELPGRFQVLPGQ 300 MRRNSLAYPSLRGANQ+LNASAALAALEALREVLPVGAQEVRTGLATVELPGRFQVLPGQ Sbjct: 241 MRRNSLAYPSLRGANQLLNASAALAALEALREVLPVGAQEVRTGLATVELPGRFQVLPGQ 300 Query: 301 PLVILDVAHNPHAAATLAQNLDNMGFHPYTYAVFGSMLDKDIEGVIGHLKDKIDHWCVTD 360 PLVILDVAHNPHAAATLAQNLDNMGFHPYTYAVFGSMLDKDIEGVIGHLKDKIDHWCVTD Sbjct: 301 PLVILDVAHNPHAAATLAQNLDNMGFHPYTYAVFGSMLDKDIEGVIGHLKDKIDHWCVTD 360 Query: 361 LPLPRAATAQQLKDKLLEAGVEPEFKPDAACTIETFESPAAAFANAQSRAPENDRIVVFG 420 LPLPRAA+AQQLKD LL AGV+PEF+ DAA +IETF +PAAA+ANA SRA ENDRIVVFG Sbjct: 361 LPLPRAASAQQLKDALLGAGVQPEFRRDAARSIETFTTPAAAYANALSRAGENDRIVVFG 420 Query: 421 SFLTVAGVMQARRPGLH 437 SFLTVAGVMQARRPGLH Sbjct: 421 SFLTVAGVMQARRPGLH 437 >ref|YP_004752531.1| folylpolyglutamate synthase [Collimonas fungivorans Ter331] gb|AEK61708.1| Folylpolyglutamate synthase [Collimonas fungivorans Ter331] Length = 440 Score = 686 bits (1770), Expect = 0.0, Method: Composition-based stats. Identities = 343/435 (78%), Positives = 381/435 (87%) Query: 3 SQASPTPATLNEWLALLEQRHFKQIDMGLDRVQAVKEKLDIRFDCPVIMVAGTNGKGSTC 62 S P TL +WL+LLE RHFK IDMGLDRV VKE+L ++FDCPVIMVAGTNGKGSTC Sbjct: 6 SNIPAKPVTLADWLSLLESRHFKTIDMGLDRVVQVKERLQLQFDCPVIMVAGTNGKGSTC 65 Query: 63 AMLESILLRAGYRVGLYIKPHFLHFNERARLSGDMASDAQLIAAFEAVEAQRGDISLTYF 122 AMLESILLRAGY+VGLYIKPHFL FNERAR+ G+ ASDA LIA+FEAVEAQRGDISLTYF Sbjct: 66 AMLESILLRAGYKVGLYIKPHFLDFNERARIGGESASDAALIASFEAVEAQRGDISLTYF 125 Query: 123 EFTTLAIMKLLADARQDVVILEVGLGGRLDAVNVIDADVAIVTSIDIDHTEYLGETREEI 182 EFTTLAIM LLA A+ DVVILEVGLGGRLDAVN++DADVAIVTS+DIDH EYLG+TRE+I Sbjct: 126 EFTTLAIMHLLAQAKLDVVILEVGLGGRLDAVNIVDADVAIVTSVDIDHVEYLGDTREKI 185 Query: 183 GFEKAGIFRPGKVAVCGDPVPPKSLIAHAEKIGADLWLMGRDFNYQGDKQQWAYGGRGMR 242 GFEKAGIFR GK AVC DPVPP+SLI HA IGADLWL+GRDFNY GDKQQW YGGRG R Sbjct: 186 GFEKAGIFRAGKTAVCSDPVPPQSLIDHANAIGADLWLLGRDFNYTGDKQQWNYGGRGQR 245 Query: 243 RNSLAYPSLRGANQILNASAALAALEALREVLPVGAQEVRTGLATVELPGRFQVLPGQPL 302 RN+L YPSLRGANQ+LNASAALAALEALR+ LPV AQEVR+G ++LPGRFQVLPGQPL Sbjct: 246 RNALGYPSLRGANQLLNASAALAALEALRDRLPVSAQEVRSGFVMMDLPGRFQVLPGQPL 305 Query: 303 VILDVAHNPHAAATLAQNLDNMGFHPYTYAVFGSMLDKDIEGVIGHLKDKIDHWCVTDLP 362 VILDVAHNPHAAATLAQNLDNMGFHPYTYAVFG+MLDKDIEG++ LK +IDHWC+T LP Sbjct: 306 VILDVAHNPHAAATLAQNLDNMGFHPYTYAVFGAMLDKDIEGIVAQLKTRIDHWCLTSLP 365 Query: 363 LPRAATAQQLKDKLLEAGVEPEFKPDAACTIETFESPAAAFANAQSRAPENDRIVVFGSF 422 LPRAA+ +QL+++LLEAGV E PDA +I +F+SP A+ANA SRA ENDRIVVFGSF Sbjct: 366 LPRAASGEQLQERLLEAGVHAEPGPDAQSSILSFDSPELAYANALSRAGENDRIVVFGSF 425 Query: 423 LTVAGVMQARRPGLH 437 LTVAGVM AR+ G H Sbjct: 426 LTVAGVMAARKSGFH 440 >ref|YP_001099529.1| bifunctional folylpolyglutamate synthase/dihydrofolate synthase [Herminiimonas arsenicoxydans] emb|CAL61402.1| FolC bifunctional protein [Includes: Folylpolyglutamate synthase (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase); Dihydrofolate synthase ] [Herminiimonas arsenicoxydans] Length = 433 Score = 657 bits (1695), Expect = 0.0, Method: Composition-based stats. Identities = 319/429 (74%), Positives = 359/429 (83%) Query: 9 PATLNEWLALLEQRHFKQIDMGLDRVQAVKEKLDIRFDCPVIMVAGTNGKGSTCAMLESI 68 P+ L EWLA LE H K IDMGLDRV+ VK+ + + F CPVI+V GTNGKGSTCAMLESI Sbjct: 5 PSNLAEWLAHLETMHPKAIDMGLDRVRQVKQAMTVEFTCPVIIVGGTNGKGSTCAMLESI 64 Query: 69 LLRAGYRVGLYIKPHFLHFNERARLSGDMASDAQLIAAFEAVEAQRGDISLTYFEFTTLA 128 LLRAGYRVGLY PH LHFNER R++G+ ASDA+L+AAF+ +EA RGD+SL+YFEFTTLA Sbjct: 65 LLRAGYRVGLYTSPHLLHFNERMRINGESASDAELLAAFDKLEAVRGDVSLSYFEFTTLA 124 Query: 129 IMKLLADARQDVVILEVGLGGRLDAVNVIDADVAIVTSIDIDHTEYLGETREEIGFEKAG 188 ++L +DA+ D VI EVGLGGRLDAVNV+DADVAIVTSIDIDHTEYLG+TRE+IGFEKAG Sbjct: 125 AIQLFSDAKLDAVIFEVGLGGRLDAVNVLDADVAIVTSIDIDHTEYLGDTREKIGFEKAG 184 Query: 189 IFRPGKVAVCGDPVPPKSLIAHAEKIGADLWLMGRDFNYQGDKQQWAYGGRGMRRNSLAY 248 IFR GK A+CGDPVPP SLI HAEKIGADLWL RDFNY GDKQQW + GRG RRNSLAY Sbjct: 185 IFRSGKAAICGDPVPPASLIEHAEKIGADLWLFNRDFNYSGDKQQWNFSGRGHRRNSLAY 244 Query: 249 PSLRGANQILNASAALAALEALREVLPVGAQEVRTGLATVELPGRFQVLPGQPLVILDVA 308 PSLRGANQ+LNAS+ LAALE LR LPVGAQEVRTGLA V+LPGRFQVLPGQP ++LDVA Sbjct: 245 PSLRGANQLLNASSVLAALEVLRLRLPVGAQEVRTGLALVDLPGRFQVLPGQPTIVLDVA 304 Query: 309 HNPHAAATLAQNLDNMGFHPYTYAVFGSMLDKDIEGVIGHLKDKIDHWCVTDLPLPRAAT 368 HNPHAAA LAQNL NMGFHPYTYAVFG+M DKDI+GVI HLK ++DHWCVTDLPLPRAAT Sbjct: 305 HNPHAAAALAQNLGNMGFHPYTYAVFGAMQDKDIDGVIAHLKGQVDHWCVTDLPLPRAAT 364 Query: 369 AQQLKDKLLEAGVEPEFKPDAACTIETFESPAAAFANAQSRAPENDRIVVFGSFLTVAGV 428 A ++DKLL A + + +I TF +PA AFANA SRA ENDRI VFGSFLTVAGV Sbjct: 365 AADIRDKLLHAYADLPPAVETERSIRTFATPADAFANALSRAGENDRITVFGSFLTVAGV 424 Query: 429 MQARRPGLH 437 M+ R H Sbjct: 425 MEFRHSEHH 433 >ref|YP_001353851.1| bifunctional folylpolyglutamate synthase / dihydrofolate synthase [Janthinobacterium sp. Marseille] gb|ABR89349.1| bifunctional folylpolyglutamate synthase / dihydrofolate synthase [Janthinobacterium sp. Marseille] Length = 432 Score = 655 bits (1689), Expect = 0.0, Method: Composition-based stats. Identities = 319/429 (74%), Positives = 359/429 (83%) Query: 9 PATLNEWLALLEQRHFKQIDMGLDRVQAVKEKLDIRFDCPVIMVAGTNGKGSTCAMLESI 68 P TL +WL LE H K IDMGLDRV+ VK+ +D++F CPVI+V GTNGKGSTCAMLESI Sbjct: 4 PKTLADWLTRLEALHPKAIDMGLDRVREVKQAMDVQFACPVIIVGGTNGKGSTCAMLESI 63 Query: 69 LLRAGYRVGLYIKPHFLHFNERARLSGDMASDAQLIAAFEAVEAQRGDISLTYFEFTTLA 128 LLRAGYRVGLY PH LHFNER R++G +D +LIAAF+ +EA RGD+SL+YFEFTTLA Sbjct: 64 LLRAGYRVGLYTSPHLLHFNERMRVNGVSCTDQELIAAFDKLEAVRGDVSLSYFEFTTLA 123 Query: 129 IMKLLADARQDVVILEVGLGGRLDAVNVIDADVAIVTSIDIDHTEYLGETREEIGFEKAG 188 ++L ADA+ D VI EVGLGGRLDAVNV+DADVAIVTS+DIDHTEYLG+TRE+IGFEKAG Sbjct: 124 AIQLFADAKLDAVIFEVGLGGRLDAVNVLDADVAIVTSVDIDHTEYLGDTREKIGFEKAG 183 Query: 189 IFRPGKVAVCGDPVPPKSLIAHAEKIGADLWLMGRDFNYQGDKQQWAYGGRGMRRNSLAY 248 IFR GK A+CGDPVPP SL+ HAEKIGADLWL RDFNY GDKQQW + GRG RRNSL Y Sbjct: 184 IFRAGKTAICGDPVPPASLVEHAEKIGADLWLFNRDFNYSGDKQQWNFSGRGRRRNSLGY 243 Query: 249 PSLRGANQILNASAALAALEALREVLPVGAQEVRTGLATVELPGRFQVLPGQPLVILDVA 308 PSLRGANQ+LNAS+ LAALEALR LPVGAQEVRTGLA V+LPGRFQVLPGQP VILDVA Sbjct: 244 PSLRGANQLLNASSVLAALEALRLRLPVGAQEVRTGLALVDLPGRFQVLPGQPTVILDVA 303 Query: 309 HNPHAAATLAQNLDNMGFHPYTYAVFGSMLDKDIEGVIGHLKDKIDHWCVTDLPLPRAAT 368 HNPHAAATLAQNLDNM F PYTYAVFG+M DKDI+GVI HLK ++DHWCVTDLPLPRAA Sbjct: 304 HNPHAAATLAQNLDNMNFAPYTYAVFGAMQDKDIDGVISHLKGRVDHWCVTDLPLPRAAG 363 Query: 369 AQQLKDKLLEAGVEPEFKPDAACTIETFESPAAAFANAQSRAPENDRIVVFGSFLTVAGV 428 A +++DKL+ A E D+ +I+TF SPA AFANA SRA ENDRI VFGSFLTVAGV Sbjct: 364 AAEIRDKLIHAYGEVPPAGDSERSIQTFTSPAEAFANALSRAGENDRIAVFGSFLTVAGV 423 Query: 429 MQARRPGLH 437 M+ R H Sbjct: 424 MEFRNSEHH 432 >ref|ZP_08273835.1| Dihydrofolate synthase [Oxalobacteraceae bacterium IMCC9480] gb|EGF32699.1| Dihydrofolate synthase [Oxalobacteraceae bacterium IMCC9480] Length = 433 Score = 618 bits (1594), Expect = e-175, Method: Composition-based stats. Identities = 312/429 (72%), Positives = 353/429 (82%) Query: 9 PATLNEWLALLEQRHFKQIDMGLDRVQAVKEKLDIRFDCPVIMVAGTNGKGSTCAMLESI 68 P TL WL LE +H IDMGLDRV AV ++ IRFDCPVI V GTNGKGSTCAMLE+I Sbjct: 5 PDTLAGWLTRLESQHPITIDMGLDRVSAVAVRMGIRFDCPVITVGGTNGKGSTCAMLEAI 64 Query: 69 LLRAGYRVGLYIKPHFLHFNERARLSGDMASDAQLIAAFEAVEAQRGDISLTYFEFTTLA 128 LL+AGYRVGL PH + FNERAR++G+ ASDA+L+ F VE RGDISL+YFEFTTLA Sbjct: 65 LLQAGYRVGLSTSPHLIDFNERARVAGESASDAELVRYFGVVEQARGDISLSYFEFTTLA 124 Query: 129 IMKLLADARQDVVILEVGLGGRLDAVNVIDADVAIVTSIDIDHTEYLGETREEIGFEKAG 188 I++L DAR DVVILEVGLGGRLDA+N+IDADVAI+TS+DIDHTEYLG TRE IGFEKAG Sbjct: 125 ILQLFVDARLDVVILEVGLGGRLDAMNIIDADVAIITSVDIDHTEYLGHTREAIGFEKAG 184 Query: 189 IFRPGKVAVCGDPVPPKSLIAHAEKIGADLWLMGRDFNYQGDKQQWAYGGRGMRRNSLAY 248 IFR GK A+C DPVPP+SL+ HA +GADLWL+GRDFNY GD+ QW YGGR RRNSL Y Sbjct: 185 IFRAGKAAICSDPVPPQSLLDHAAAVGADLWLLGRDFNYMGDQLQWNYGGREQRRNSLGY 244 Query: 249 PSLRGANQILNASAALAALEALREVLPVGAQEVRTGLATVELPGRFQVLPGQPLVILDVA 308 PSLRGANQ+LNA+AALAALE LR LPVGAQEVRTGL V+LPGRFQVLPG+P VILDVA Sbjct: 245 PSLRGANQLLNAAAALAALEVLRLRLPVGAQEVRTGLVLVDLPGRFQVLPGRPTVILDVA 304 Query: 309 HNPHAAATLAQNLDNMGFHPYTYAVFGSMLDKDIEGVIGHLKDKIDHWCVTDLPLPRAAT 368 HNPHAAATL+QN NMGFHPYTYAVFG+M DKDI+GVI LK ++DHWC+TDLPLPR AT Sbjct: 305 HNPHAAATLSQNFGNMGFHPYTYAVFGAMHDKDIDGVIAQLKGQVDHWCLTDLPLPRGAT 364 Query: 369 AQQLKDKLLEAGVEPEFKPDAACTIETFESPAAAFANAQSRAPENDRIVVFGSFLTVAGV 428 A+Q+++KLL AGV P K DA CTI+ F +PA AFANA RA ENDRI VFGSF+TVAGV Sbjct: 365 AEQIREKLLAAGVTPTDKADAECTIQCFATPAEAFANATGRAGENDRIAVFGSFVTVAGV 424 Query: 429 MQARRPGLH 437 M R H Sbjct: 425 MAFRAAANH 433