BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3979.p (474 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003777960.1| major facilitator superfamily permease [Herb... 627 e-177 ref|YP_004154052.1| major facilitator superfamily protein [Vario... 576 e-162 ref|YP_586941.1| transporter of the major facilitator superfamil... 572 e-161 ref|YP_002943493.1| major facilitator superfamily protein [Vario... 567 e-159 ref|YP_002007305.1| transporter; major facilitator superfamily m... 556 e-156 >ref|YP_003777960.1| major facilitator superfamily permease [Herbaspirillum seropedicae SmR1] gb|ADJ66052.1| permease of the major facilitator superfamily protein [Herbaspirillum seropedicae SmR1] Length = 478 Score = 627 bits (1618), Expect = e-177, Method: Composition-based stats. Identities = 399/475 (84%), Positives = 430/475 (90%), Gaps = 1/475 (0%) Query: 1 MIATPSATIPARLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSLGSVLERSDTLALDA 60 M + +A++PARLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGS+GSVLER DTL LDA Sbjct: 1 MPLSAAASLPARLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSIGSVLERPDTLGLDA 60 Query: 61 AQVGWTGSLYIAGTVLGALVFGRLTDRLGRKRLFMLTLMLYMAATLATAFAQDFLFLALC 120 AQVGWTGSLYIAG V+GALVFGRLTDRLGRK+LFM+TL LYMAATLA+AFA DFL+ ALC Sbjct: 61 AQVGWTGSLYIAGAVVGALVFGRLTDRLGRKKLFMITLALYMAATLASAFATDFLWFALC 120 Query: 121 RFVTGLGIGGEYAAINSAIDELVPARVRGRVNLIINASFWIGAALGAGLSLVILDPQVMG 180 R TGLGIGGEYAAINSAIDELVPARVRGRVNL+INASFWIGAALGAGLSLVILD +V+G Sbjct: 121 RLATGLGIGGEYAAINSAIDELVPARVRGRVNLVINASFWIGAALGAGLSLVILDERVLG 180 Query: 181 AALGWRACFLLGAVLAVAVLLVRRHVPESPRWLLMHGRHAEAEAVVRRIEAEVEQQHGPL 240 +GWR CFLLGAVLAVA++LVRRHVPESPRWL MHG HA AEAVVR IEA+V +HG L Sbjct: 181 PVMGWRVCFLLGAVLAVAIVLVRRHVPESPRWLAMHGHHARAEAVVREIEAQVMAEHGTL 240 Query: 241 PAV-ELAPSASTQSGTAGSGMLPWREIAHVLLHRYRQRSVMVALMMVAQAFVYNAIFFTY 299 PA+ AP S++S G+L WREIA VLLH YR RS+MVALMMVAQAFVYNAIFFTY Sbjct: 241 PALPTAAPGESSRSPGQAVGLLSWREIAQVLLHHYRARSLMVALMMVAQAFVYNAIFFTY 300 Query: 300 SLVLTRFFQVPDHRVALYIFPFALGNVLGPLLLGHLFDSIGRRRMIAATYLLSGAGLAAT 359 SLVLTRFFQVPD RVALY+FPFALGNVLGPLLLGHLFDSIGRRRMIAATYLL+G GLAAT Sbjct: 301 SLVLTRFFQVPDTRVALYLFPFALGNVLGPLLLGHLFDSIGRRRMIAATYLLAGVGLAAT 360 Query: 360 AWAFNAGMLDARSLALCWSAVFFVASAAASSAYLTASEVFPLRMRAMAISIFYAIGTGVG 419 A AFNAG LDA LALCWSAVFFVASAAASSAYLTASEVFPL+MRAMAI+IFYAIGTGVG Sbjct: 361 AAAFNAGWLDALGLALCWSAVFFVASAAASSAYLTASEVFPLQMRAMAIAIFYAIGTGVG 420 Query: 420 GFVAPVLLGWLIASGDRHAVAAGYALGACLALLAGVCALRFAVDAERRTLEEVAE 474 GF+AP LLGWLIASGDR AVAAGYA+GA LALLAG+CALR+AVDAERRTLEEVAE Sbjct: 421 GFIAPALLGWLIASGDRQAVAAGYAVGAVLALLAGLCALRWAVDAERRTLEEVAE 475 >ref|YP_004154052.1| major facilitator superfamily protein [Variovorax paradoxus EPS] gb|ADU35941.1| major facilitator superfamily MFS_1 [Variovorax paradoxus EPS] Length = 479 Score = 576 bits (1484), Expect = e-162, Method: Composition-based stats. Identities = 342/468 (73%), Positives = 385/468 (82%), Gaps = 4/468 (0%) Query: 6 SATIPARLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSLGSVLERSDTLALDAAQVGW 65 S+ IPARLDRLPWSRWHWRVVIALGVAW+LDGLEVTLVGS+G+VLER DTL L A ++GW Sbjct: 5 SSDIPARLDRLPWSRWHWRVVIALGVAWILDGLEVTLVGSIGAVLERPDTLGLTAGEIGW 64 Query: 66 TGSLYIAGTVLGALVFGRLTDRLGRKRLFMLTLMLYMAATLATAFAQDFLFLALCRFVTG 125 +GS+YIAG V+GALVFGRLTDRLGRK+LF++TL +Y TLATAF+ DF F ALCRFVTG Sbjct: 65 SGSIYIAGAVVGALVFGRLTDRLGRKKLFLITLAVYTVGTLATAFSPDFAFFALCRFVTG 124 Query: 126 LGIGGEYAAINSAIDELVPARVRGRVNLIINASFWIGAALGAGLSLVILDPQVMGAALGW 185 LGIGGEYAAINSAIDEL+PARVRGRVNL IN SFWIGAALGA LSLV+LD +V+G GW Sbjct: 125 LGIGGEYAAINSAIDELIPARVRGRVNLAINGSFWIGAALGAALSLVLLDARVIGPVWGW 184 Query: 186 RACFLLGAVLAVAVLLVRRHVPESPRWLLMHGRHAEAEAVVRRIEAEVEQQHGPLPAVEL 245 RA F LGAVLAVA+LLVRRHVPESPRWL+ HGR EAE +V IE EV+ QHGPLP Sbjct: 185 RAGFALGAVLAVAILLVRRHVPESPRWLIAHGRVDEAERIVAGIEHEVQAQHGPLP---- 240 Query: 246 APSASTQSGTAGSGMLPWREIAHVLLHRYRQRSVMVALMMVAQAFVYNAIFFTYSLVLTR 305 AP A + RE+A VLL RY RSV+ A +M++QAF YNAIFFTY+LVLTR Sbjct: 241 APRGHVNYTAARANSPSMREVARVLLRRYTARSVVAAALMISQAFFYNAIFFTYALVLTR 300 Query: 306 FFQVPDHRVALYIFPFALGNVLGPLLLGHLFDSIGRRRMIAATYLLSGAGLAATAWAFNA 365 F+ VP+ RVALYIFPFALGNVLGPLLLG LFDS+GRRRMIA TY+ +G GLA T WAF Sbjct: 301 FYGVPEGRVALYIFPFALGNVLGPLLLGPLFDSVGRRRMIALTYVFAGVGLALTGWAFMN 360 Query: 366 GMLDARSLALCWSAVFFVASAAASSAYLTASEVFPLRMRAMAISIFYAIGTGVGGFVAPV 425 G LDARS ALCWSAVFF+ASAAASSAYLT SEVFPL MRAMAI+IFYAIG G GGFVAPV Sbjct: 361 GWLDARSQALCWSAVFFLASAAASSAYLTVSEVFPLEMRAMAIAIFYAIGMGAGGFVAPV 420 Query: 426 LLGWLIASGDRHAVAAGYALGACLALLAGVCALRFAVDAERRTLEEVA 473 L G LI +G R AV AGY +GA L ++AG+ ALR+A DAER+ LEEVA Sbjct: 421 LFGELIETGSRGAVMAGYLIGAALVIVAGLLALRYAADAERKPLEEVA 468 >ref|YP_586941.1| transporter of the major facilitator superfamily, permease [Cupriavidus metallidurans CH34] gb|ABF11672.1| putative transporter of the major facilitator superfamily, permease [Cupriavidus metallidurans CH34] Length = 514 Score = 572 bits (1474), Expect = e-161, Method: Composition-based stats. Identities = 335/467 (71%), Positives = 388/467 (83%), Gaps = 4/467 (0%) Query: 7 ATIPARLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSLGSVLERSDTLALDAAQVGWT 66 + IPARLDRLPWS WHWRV IALG+AWVLDGLEVTLVGS+G+VLER DTLAL+A QVGW+ Sbjct: 44 SDIPARLDRLPWSAWHWRVAIALGIAWVLDGLEVTLVGSVGAVLERPDTLALNATQVGWS 103 Query: 67 GSLYIAGTVLGALVFGRLTDRLGRKRLFMLTLMLYMAATLATAFAQDFLFLALCRFVTGL 126 GSLY+ G V+GAL FGR+ DRLGRK+LF+ TL +YMAATLATAF+ +F F A CRFVTGL Sbjct: 104 GSLYVLGAVIGALAFGRMADRLGRKKLFLATLFVYMAATLATAFSPNFAFFAACRFVTGL 163 Query: 127 GIGGEYAAINSAIDELVPARVRGRVNLIINASFWIGAALGAGLSLVILDPQVMGAALGWR 186 GIGGEYAAINSAIDEL+PARVRGRVNL IN SFW+GAALGAGLSL++LDP+V+G GWR Sbjct: 164 GIGGEYAAINSAIDELIPARVRGRVNLAINGSFWLGAALGAGLSLLLLDPRVLGPVWGWR 223 Query: 187 ACFLLGAVLAVAVLLVRRHVPESPRWLLMHGRHAEAEAVVRRIEAEVEQQHGPLPAVELA 246 ACF LGA+LAVA++L+RRHVPESPRWL HGRHAEAE V+ IEA + ++HGPLP V A Sbjct: 224 ACFALGALLAVAIVLIRRHVPESPRWLATHGRHAEAEQVIAGIEAAITRRHGPLPPVHDA 283 Query: 247 PSASTQSGTAGSGMLPWREIAHVLLHRYRQRSVMVALMMVAQAFVYNAIFFTYSLVLTRF 306 G + P R++ +L+ RYR RS + +MVAQAF YNAIFFTY+LVLTRF Sbjct: 284 VLVY----YGGKPVPPLRDVVRLLVRRYRTRSAVTFALMVAQAFFYNAIFFTYALVLTRF 339 Query: 307 FQVPDHRVALYIFPFALGNVLGPLLLGHLFDSIGRRRMIAATYLLSGAGLAATAWAFNAG 366 VP+ RVALYIFPFA+GN LGPLLLG LFD IGRR+MIA TY+LSG GLAAT WAF +G Sbjct: 340 LGVPEERVALYIFPFAIGNALGPLLLGPLFDRIGRRKMIALTYVLSGIGLAATGWAFMSG 399 Query: 367 MLDARSLALCWSAVFFVASAAASSAYLTASEVFPLRMRAMAISIFYAIGTGVGGFVAPVL 426 LDARS ALCWSAVFF+ASAAASSAYLTASEVFPL MRA+AIS+FYA+GTGVGGF+APVL Sbjct: 400 WLDARSQALCWSAVFFLASAAASSAYLTASEVFPLEMRALAISVFYAVGTGVGGFIAPVL 459 Query: 427 LGWLIASGDRHAVAAGYALGACLALLAGVCALRFAVDAERRTLEEVA 473 G LI +G R AVA GYA+GA L ++AG AL++ VDAER+ LEEVA Sbjct: 460 FGALIETGSRGAVAVGYAIGATLVIVAGAMALKYGVDAERKPLEEVA 506 >ref|YP_002943493.1| major facilitator superfamily protein [Variovorax paradoxus S110] gb|ACS18227.1| major facilitator superfamily MFS_1 [Variovorax paradoxus S110] Length = 483 Score = 567 bits (1462), Expect = e-159, Method: Composition-based stats. Identities = 339/473 (71%), Positives = 383/473 (80%), Gaps = 4/473 (0%) Query: 1 MIATPSATIPARLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSLGSVLERSDTLALDA 60 M A + IPARLDRLPWSRWHWRVV+ALGVAWVLDGLEVTLVGS+G+VLER DTL L A Sbjct: 1 MTAAVHSDIPARLDRLPWSRWHWRVVVALGVAWVLDGLEVTLVGSIGAVLERPDTLGLSA 60 Query: 61 AQVGWTGSLYIAGTVLGALVFGRLTDRLGRKRLFMLTLMLYMAATLATAFAQDFLFLALC 120 ++GW+GS+YIAG V+GAL+FGRLTDRLGRK+LF++TL++Y TLATAF+ DF F ALC Sbjct: 61 GEIGWSGSIYIAGAVIGALLFGRLTDRLGRKKLFLVTLVVYTLGTLATAFSPDFAFFALC 120 Query: 121 RFVTGLGIGGEYAAINSAIDELVPARVRGRVNLIINASFWIGAALGAGLSLVILDPQVMG 180 RF+TGLGIGGEYAAINSAIDEL+PARVRGRVNL IN SFWIGAALGAGLSLV+LD +V+G Sbjct: 121 RFITGLGIGGEYAAINSAIDELIPARVRGRVNLAINGSFWIGAALGAGLSLVLLDARVIG 180 Query: 181 AALGWRACFLLGAVLAVAVLLVRRHVPESPRWLLMHGRHAEAEAVVRRIEAEVEQQHGPL 240 GWRA F LGAVLAVA+LLVRRHVPESPRWL+ HGR EA +V IEAEV QHGPL Sbjct: 181 PVWGWRAGFALGAVLAVAILLVRRHVPESPRWLMAHGRADEALRIVETIEAEVRAQHGPL 240 Query: 241 PAVELAPSASTQSGTAGSGMLPWREIAHVLLHRYRQRSVMVALMMVAQAFVYNAIFFTYS 300 E G RE+AHVLL RYR RSV+ +MV+QAF YNAIFFTY+ Sbjct: 241 ALAE----GRVAYGGGHHRSPSMREVAHVLLRRYRARSVVAVALMVSQAFFYNAIFFTYA 296 Query: 301 LVLTRFFQVPDHRVALYIFPFALGNVLGPLLLGHLFDSIGRRRMIAATYLLSGAGLAATA 360 LVLTRF+ V + VALYIFPFALGNVLGPLLLG LFDS+GRR+MIA TY+L+G GLA T Sbjct: 297 LVLTRFYGVAEDNVALYIFPFALGNVLGPLLLGPLFDSVGRRKMIALTYVLAGVGLAFTG 356 Query: 361 WAFNAGMLDARSLALCWSAVFFVASAAASSAYLTASEVFPLRMRAMAISIFYAIGTGVGG 420 WAF G LDARS ALCWSAVFF+ASAAASSAYLT SEVFPL MRAMAI+IFYAIG G GG Sbjct: 357 WAFMMGWLDARSQALCWSAVFFLASAAASSAYLTVSEVFPLEMRAMAIAIFYAIGMGAGG 416 Query: 421 FVAPVLLGWLIASGDRHAVAAGYALGACLALLAGVCALRFAVDAERRTLEEVA 473 FVAPVL G LI +G R AV GYA+GA L ++AG+ ALR+A DAE + LEEVA Sbjct: 417 FVAPVLFGVLIETGSRGAVMVGYAIGATLVIVAGLLALRYAADAECKPLEEVA 469 >ref|YP_002007305.1| transporter; major facilitator superfamily mfs-1 [Cupriavidus taiwanensis LMG 19424] emb|CAQ71244.1| putative transporter; Major facilitator superfamily MFS-1 [Cupriavidus taiwanensis LMG 19424] Length = 488 Score = 556 bits (1433), Expect = e-156, Method: Composition-based stats. Identities = 337/465 (72%), Positives = 379/465 (81%), Gaps = 3/465 (0%) Query: 9 IPARLDRLPWSRWHWRVVIALGVAWVLDGLEVTLVGSLGSVLERSDTLALDAAQVGWTGS 68 IP RLDRLPWSRWHWRV IALGVAWVLDGLEVTLVGS+G+VLER DTL L A +VGW+GS Sbjct: 20 IPGRLDRLPWSRWHWRVAIALGVAWVLDGLEVTLVGSVGAVLERPDTLGLSATEVGWSGS 79 Query: 69 LYIAGTVLGALVFGRLTDRLGRKRLFMLTLMLYMAATLATAFAQDFLFLALCRFVTGLGI 128 LYIAG VLGALVFGR+ DR+GRKRLF+ TL +YM ATLATAFA DF A CRF TGLGI Sbjct: 80 LYIAGAVLGALVFGRMADRMGRKRLFLATLAVYMVATLATAFAPDFAVFAACRFCTGLGI 139 Query: 129 GGEYAAINSAIDELVPARVRGRVNLIINASFWIGAALGAGLSLVILDPQVMGAALGWRAC 188 GGEYAAINSAIDEL+PARVRGRVNL IN SFW+GAALGAGLSLV+LD +V G GWRAC Sbjct: 140 GGEYAAINSAIDELIPARVRGRVNLAINGSFWLGAALGAGLSLVLLDARVFGPVWGWRAC 199 Query: 189 FLLGAVLAVAVLLVRRHVPESPRWLLMHGRHAEAEAVVRRIEAEVEQQHGPLPAVELAPS 248 F LGAVLA+A++LVRRHVPESPRWL HGR EAE ++ IE E+ HGPLP V + Sbjct: 200 FALGAVLAIAIVLVRRHVPESPRWLATHGRLDEAERIIAAIETEIRATHGPLPPVSPDCA 259 Query: 249 ASTQSGTAGSGMLPWREIAHVLLHRYRQRSVMVALMMVAQAFVYNAIFFTYSLVLTRFFQ 308 A A G+ E+ +LL R+RQRSV+ +MVAQAF YNAIFFTY+LVL+RF+ Sbjct: 260 AVAMRRRAAPGV---GEVMRLLLRRFRQRSVITLALMVAQAFFYNAIFFTYALVLSRFYG 316 Query: 309 VPDHRVALYIFPFALGNVLGPLLLGHLFDSIGRRRMIAATYLLSGAGLAATAWAFNAGML 368 VP+ RVALYIFPFALGN LGPLLLG LFD +GRRRMIAATY+LSG GLA T WAF G L Sbjct: 317 VPEARVALYIFPFALGNALGPLLLGPLFDHVGRRRMIAATYVLSGIGLALTGWAFVQGWL 376 Query: 369 DARSLALCWSAVFFVASAAASSAYLTASEVFPLRMRAMAISIFYAIGTGVGGFVAPVLLG 428 DAR+ ALCWSAVFF+ASAAASSAYLTASEVFPL MRA+AIS+FYA+GTG GGFVAP+LLG Sbjct: 377 DARTQALCWSAVFFLASAAASSAYLTASEVFPLEMRALAISVFYAVGTGTGGFVAPLLLG 436 Query: 429 WLIASGDRHAVAAGYALGACLALLAGVCALRFAVDAERRTLEEVA 473 LI SG R AVAAGY GA L ++AG+ ALRF +DAERR LE +A Sbjct: 437 ALIESGSREAVAAGYGFGAALVIIAGLLALRFGIDAERRPLEHIA 481