BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3691.p (863 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776463.1| methylmalonate-semialdehyde dehydrogenase [H... 999 0.0 ref|YP_004753421.1| methylmalonate-semialdehyde dehydrogenase [C... 904 0.0 ref|YP_004125503.1| methylmalonate-semialdehyde dehydrogenase [A... 790 0.0 ref|XP_002945012.1| PREDICTED: methylmalonate-semialdehyde dehyd... 780 0.0 ref|ZP_06686444.1| methylmalonate semialdehyde dehydrogenase [Ac... 767 0.0 >ref|YP_003776463.1| methylmalonate-semialdehyde dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ64555.1| methylmalonate-semialdehyde dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 506 Score = 999 bits (2584), Expect = 0.0, Method: Composition-based stats. Identities = 489/493 (99%), Positives = 491/493 (99%) Query: 362 MSQANIPNVPLYLNGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKETFK 421 MSQANIPNVPLYLNGE VQSTSKEWRDV+NPATQEVVARVPFATKEEVDRAVANAKETFK Sbjct: 1 MSQANIPNVPLYLNGEKVQSTSKEWRDVLNPATQEVVARVPFATKEEVDRAVANAKETFK 60 Query: 422 TWRNTSLAQRMRIMLKFQQLLRENIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHACSI 481 TWRNTSLAQRMRIMLKFQQLLRENIAPLAE+ITREHGKTLPDAEGEVMRGLEVVEHACSI Sbjct: 61 TWRNTSLAQRMRIMLKFQQLLRENIAPLAELITREHGKTLPDAEGEVMRGLEVVEHACSI 120 Query: 482 TSLQLGELAENVAGGVDVYTLYQPLGVGAGITAFNFPVMLPCFMFPIAVACGNTFVLKPS 541 TSLQLGELAENVAGGVDVYTLYQPLGVGAGITAFNFPVMLPCFMFPIAVACGNTFVLKPS Sbjct: 121 TSLQLGELAENVAGGVDVYTLYQPLGVGAGITAFNFPVMLPCFMFPIAVACGNTFVLKPS 180 Query: 542 EQDPTSSLFLVELANQAGLPPGVLNVVHGGPDVANMICDHPDIKAVSFIGSTHVGTHIYR 601 EQDPTSSLFLVELANQAGLPPGVLNVVHGGPDVANMICDHPDIKAVSFIGSTHVGTHIYR Sbjct: 181 EQDPTSSLFLVELANQAGLPPGVLNVVHGGPDVANMICDHPDIKAVSFIGSTHVGTHIYR 240 Query: 602 RASEAGKRAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGQTRE 661 RASEAGKRAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGQTRE Sbjct: 241 RASEAGKRAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGQTRE 300 Query: 662 WIPEIVERSKAMKVGPGTDRKADVGPLVSKAAKERVERLIASGVEQGAKLLLDGRNCKVA 721 WIPEIVERSKAMKVGPGTDRKADVGPLVSKAAKERVERLIASGVEQGAKLLLDGRNCKVA Sbjct: 301 WIPEIVERSKAMKVGPGTDRKADVGPLVSKAAKERVERLIASGVEQGAKLLLDGRNCKVA 360 Query: 722 GSENGNFVGPTVFTGVKPEMDIYAQEIFGPAMCIVELDTLDEAIAFINANPNGNGTSIFT 781 GSENGNFVGPTVFTGVKPEMDIY QEIFGPAMCIVELDTLDEAIAFINANPNGNGTSIFT Sbjct: 361 GSENGNFVGPTVFTGVKPEMDIYTQEIFGPAMCIVELDTLDEAIAFINANPNGNGTSIFT 420 Query: 782 SSGYAARKFQNEIDVGQVGINVPIPVPVAYFSFTGSRASKLGDLGPNGKQAVTFWTQTKT 841 SSGYAARKFQNEIDVGQVGINVPIPVPVAYFSFTGSRASKLGDLGPNGKQAVTFWTQTKT Sbjct: 421 SSGYAARKFQNEIDVGQVGINVPIPVPVAYFSFTGSRASKLGDLGPNGKQAVTFWTQTKT 480 Query: 842 VTARWYAPDEEAG 854 VTARWYAPDEEAG Sbjct: 481 VTARWYAPDEEAG 493 >ref|YP_004753421.1| methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans Ter331] gb|AEK62598.1| Methylmalonate-semialdehyde dehydrogenase [Collimonas fungivorans Ter331] Length = 507 Score = 904 bits (2335), Expect = 0.0, Method: Composition-based stats. Identities = 432/505 (85%), Positives = 473/505 (93%) Query: 359 EIAMSQANIPNVPLYLNGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKE 418 E A+ NIPN+PLY+ G+ VQS S EWRDV+NPATQEVVARVPFATK EVD AVA+AK+ Sbjct: 3 EEAIMSTNIPNIPLYVGGKTVQSASTEWRDVLNPATQEVVARVPFATKAEVDHAVADAKQ 62 Query: 419 TFKTWRNTSLAQRMRIMLKFQQLLRENIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHA 478 F +WRNTSLAQRMRIMLKFQQLLRENIAPLAE+ITREHGKTLPDAEGEVMRGLEVVEHA Sbjct: 63 AFASWRNTSLAQRMRIMLKFQQLLRENIAPLAELITREHGKTLPDAEGEVMRGLEVVEHA 122 Query: 479 CSITSLQLGELAENVAGGVDVYTLYQPLGVGAGITAFNFPVMLPCFMFPIAVACGNTFVL 538 CSITSLQLGELAEN A GVDVYT+ QPLGVGAGITAFNFPVMLPCFMFP+AVACGNTF+L Sbjct: 123 CSITSLQLGELAENAATGVDVYTINQPLGVGAGITAFNFPVMLPCFMFPVAVACGNTFIL 182 Query: 539 KPSEQDPTSSLFLVELANQAGLPPGVLNVVHGGPDVANMICDHPDIKAVSFIGSTHVGTH 598 KPSEQDP+SSLFLVELA QAGLPPGVLNVVHGGP+VANM+CDHPDIKA+SFIGST VGTH Sbjct: 183 KPSEQDPSSSLFLVELAQQAGLPPGVLNVVHGGPEVANMLCDHPDIKAISFIGSTTVGTH 242 Query: 599 IYRRASEAGKRAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGQ 658 IYRRASEAGKRAQCMMGAKNHCIVLPDA KDQAINNLLGAAFGAAGQRCMANS+V+LVG+ Sbjct: 243 IYRRASEAGKRAQCMMGAKNHCIVLPDANKDQAINNLLGAAFGAAGQRCMANSMVLLVGK 302 Query: 659 TREWIPEIVERSKAMKVGPGTDRKADVGPLVSKAAKERVERLIASGVEQGAKLLLDGRNC 718 R W+PEIVERS+ +K+GPG+DRKAD+GP+VSKAAK R ERLI SGVEQGA+LLLDGRNC Sbjct: 303 ARSWLPEIVERSRGLKIGPGSDRKADLGPMVSKAAKARTERLIGSGVEQGARLLLDGRNC 362 Query: 719 KVAGSENGNFVGPTVFTGVKPEMDIYAQEIFGPAMCIVELDTLDEAIAFINANPNGNGTS 778 +VAG +GNFVGPT+F+GV EMDIY QEIFGPAMC+VEL+TLDEAIAFINANPNGNGTS Sbjct: 363 QVAGYPDGNFVGPTIFSGVTAEMDIYTQEIFGPAMCVVELETLDEAIAFINANPNGNGTS 422 Query: 779 IFTSSGYAARKFQNEIDVGQVGINVPIPVPVAYFSFTGSRASKLGDLGPNGKQAVTFWTQ 838 IFTSSG++ARKFQNEIDVGQVGINVPIPVPVAYFSFTGSRASKLGDLGPNGKQAV FWTQ Sbjct: 423 IFTSSGWSARKFQNEIDVGQVGINVPIPVPVAYFSFTGSRASKLGDLGPNGKQAVQFWTQ 482 Query: 839 TKTVTARWYAPDEEAGQVNTTITLK 863 TKTVTARW+APD + G++NTTI++K Sbjct: 483 TKTVTARWFAPDADGGEINTTISMK 507 >ref|YP_004125503.1| methylmalonate-semialdehyde dehydrogenase [Alicycliphilus denitrificans BC] ref|YP_004386738.1| methylmalonate-semialdehyde dehydrogenase [Alicycliphilus denitrificans K601] gb|ADU98615.1| methylmalonate-semialdehyde dehydrogenase [Alicycliphilus denitrificans BC] gb|AEB83222.1| methylmalonate-semialdehyde dehydrogenase [Alicycliphilus denitrificans K601] Length = 501 Score = 790 bits (2040), Expect = 0.0, Method: Composition-based stats. Identities = 381/492 (77%), Positives = 433/492 (88%), Gaps = 1/492 (0%) Query: 373 YLNGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKETFKTWRNTSLAQRM 432 ++ G+ S S EWRDV NPATQEVVARVPFAT+EEV+ AVANA+E F+TWR TSL+ RM Sbjct: 10 FIGGKPYPSKSAEWRDVTNPATQEVVARVPFATREEVELAVANAQEAFQTWRETSLSARM 69 Query: 433 RIMLKFQQLLRENIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHACSITSLQLGELAEN 492 RIMLK Q L+RE+ A +A++ITREHGKTLPDAEGEV RGLEVVEHACSIT+LQLGE+AEN Sbjct: 70 RIMLKLQHLIREHQAEIAQLITREHGKTLPDAEGEVGRGLEVVEHACSITTLQLGEIAEN 129 Query: 493 VAGGVDVYTLYQPLGVGAGITAFNFPVMLPCFMFPIAVACGNTFVLKPSEQDPTSSLFLV 552 A GVDVY L QPLGVGAGITAFNFPVMLPCFMFP+A+ACGNTFVLKPSEQDP+S++ LV Sbjct: 130 AATGVDVYNLLQPLGVGAGITAFNFPVMLPCFMFPMAIACGNTFVLKPSEQDPSSTMRLV 189 Query: 553 ELANQAGLPPGVLNVVHGGPDVANMICDHPDIKAVSFIGSTHVGTHIYRRASEAGKRAQC 612 ELA++AG+PPGVLNV+HGGP+VA+M+CDHPDIKA+SFIGSTHVGTHIYRRASEAGKR Q Sbjct: 190 ELAHEAGVPPGVLNVIHGGPEVADMLCDHPDIKALSFIGSTHVGTHIYRRASEAGKRVQS 249 Query: 613 MMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGQTREWIPEIVERSKA 672 MMGAKNHC+V+PDAPK+ A+NNLLG+AFGAAGQRCMANSV V VG R+W+PE+V +SKA Sbjct: 250 MMGAKNHCVVMPDAPKEHALNNLLGSAFGAAGQRCMANSVAVFVGAARDWLPELVAKSKA 309 Query: 673 MKVGPGTDRKADVGPLVSKAAKERVERLIASGVEQGAKLLLDGRNCKVAGSENGNFVGPT 732 MKVGPGTDR AD+GPLV+ AK+RV LI SGV QGAKLLLDGR C V G E GNFVGPT Sbjct: 310 MKVGPGTDRSADLGPLVNPRAKQRVLGLIDSGVAQGAKLLLDGRACTVPGYEQGNFVGPT 369 Query: 733 VFTGVKPEMDIYAQEIFGPAMCIVELDTLDEAIAFINANPNGNGTSIFTSSGYAARKFQN 792 VF V +MDIY QEIFGP + +V +DTL++AIAFIN NPNGNGTSIFTSSG+AARKFQ+ Sbjct: 370 VFADVTDQMDIYQQEIFGPVLNVVCVDTLEDAIAFINRNPNGNGTSIFTSSGWAARKFQH 429 Query: 793 EIDVGQVGINVPIPVPVAYFSFTGSRASKLGDLGPNGKQAVTFWTQTKTVTARWYAPD-E 851 +I+VGQVGINVPIPVPVAYFSFTGSRASKLGDLGPNGKQAV FWTQTKTVTARWY Sbjct: 430 DINVGQVGINVPIPVPVAYFSFTGSRASKLGDLGPNGKQAVQFWTQTKTVTARWYEDHGS 489 Query: 852 EAGQVNTTITLK 863 + VNTTIT+K Sbjct: 490 SSDAVNTTITMK 501 >ref|XP_002945012.1| PREDICTED: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial-like, partial [Xenopus (Silurana) tropicalis] Length = 477 Score = 780 bits (2014), Expect = 0.0, Method: Composition-based stats. Identities = 372/477 (77%), Positives = 427/477 (89%) Query: 387 RDVINPATQEVVARVPFATKEEVDRAVANAKETFKTWRNTSLAQRMRIMLKFQQLLRENI 446 RDV NPATQEVVARVPFAT++EV+ AVANA++ F+TWR TSLA RMRIMLK QQLLRE+ Sbjct: 1 RDVTNPATQEVVARVPFATRDEVNLAVANAQQAFQTWRETSLAARMRIMLKLQQLLREHT 60 Query: 447 APLAEMITREHGKTLPDAEGEVMRGLEVVEHACSITSLQLGELAENVAGGVDVYTLYQPL 506 A LA++ITREHGKTLPDAEGEV RGLEVVEHACSIT+LQLGE+AEN A GVDVY L QPL Sbjct: 61 AELAQLITREHGKTLPDAEGEVARGLEVVEHACSITTLQLGEMAENAATGVDVYNLLQPL 120 Query: 507 GVGAGITAFNFPVMLPCFMFPIAVACGNTFVLKPSEQDPTSSLFLVELANQAGLPPGVLN 566 GVGAGITAFNFPVMLPCFMFP+A+ACGNTFVLKPSEQDP+S++ LVELA++AG+PPGVLN Sbjct: 121 GVGAGITAFNFPVMLPCFMFPMAIACGNTFVLKPSEQDPSSTMRLVELAHEAGVPPGVLN 180 Query: 567 VVHGGPDVANMICDHPDIKAVSFIGSTHVGTHIYRRASEAGKRAQCMMGAKNHCIVLPDA 626 V+HGGP+VA+++CDHPDIKA+SFIGSTHVGTH+YRRASEAGKR Q MMGAKNHC+V+PDA Sbjct: 181 VIHGGPEVADVLCDHPDIKALSFIGSTHVGTHVYRRASEAGKRVQSMMGAKNHCVVMPDA 240 Query: 627 PKDQAINNLLGAAFGAAGQRCMANSVVVLVGQTREWIPEIVERSKAMKVGPGTDRKADVG 686 PK+ A+NNLLG+AFGAAGQRCMANSV VLVG R+W+PE+VE+SKAMKVGPG+DR AD+G Sbjct: 241 PKEHALNNLLGSAFGAAGQRCMANSVAVLVGAARDWLPELVEKSKAMKVGPGSDRDADLG 300 Query: 687 PLVSKAAKERVERLIASGVEQGAKLLLDGRNCKVAGSENGNFVGPTVFTGVKPEMDIYAQ 746 PLV+ A++RV LI +GV QGA+LLLDGR C V G E GNFVGPTVF V MDIY Q Sbjct: 301 PLVNPRARQRVLDLIDTGVAQGARLLLDGRGCVVPGYEKGNFVGPTVFADVTEAMDIYQQ 360 Query: 747 EIFGPAMCIVELDTLDEAIAFINANPNGNGTSIFTSSGYAARKFQNEIDVGQVGINVPIP 806 EIFGP + +V +DTL++AIAFIN NPNGNGTSIFTSSG+AAR+FQ++I+VGQVGINVPIP Sbjct: 361 EIFGPVLNVVCVDTLEDAIAFINRNPNGNGTSIFTSSGWAARRFQHDINVGQVGINVPIP 420 Query: 807 VPVAYFSFTGSRASKLGDLGPNGKQAVTFWTQTKTVTARWYAPDEEAGQVNTTITLK 863 VPVAYFSFTGSRASKLGDLGPNGKQAV FWTQTKTVTARWY + VNTTI++K Sbjct: 421 VPVAYFSFTGSRASKLGDLGPNGKQAVQFWTQTKTVTARWYEEGSRSDGVNTTISMK 477 >ref|ZP_06686444.1| methylmalonate semialdehyde dehydrogenase [Achromobacter piechaudii ATCC 43553] gb|EFF76636.1| methylmalonate semialdehyde dehydrogenase [Achromobacter piechaudii ATCC 43553] Length = 497 Score = 767 bits (1981), Expect = 0.0, Method: Composition-based stats. Identities = 372/499 (74%), Positives = 422/499 (84%), Gaps = 3/499 (0%) Query: 365 ANIPNVPLYLNGEHVQSTSKEWRDVINPATQEVVARVPFATKEEVDRAVANAKETFKTWR 424 + +P VPL + G+ VQS S EWRDVINPATQEVVA+VPFAT+EE+D AV+NAKE FKTWR Sbjct: 2 SEVPRVPLLIGGKLVQSKSTEWRDVINPATQEVVAKVPFATREELDLAVSNAKEAFKTWR 61 Query: 425 NTSLAQRMRIMLKFQQLLRENIAPLAEMITREHGKTLPDAEGEVMRGLEVVEHACSITSL 484 N+ RMR+MLKFQ+LLR N LAEMITREHGKTLPDAEGE+ RGLEVVEHACSI +L Sbjct: 62 NSGQGTRMRVMLKFQELLRANTGKLAEMITREHGKTLPDAEGEIGRGLEVVEHACSIANL 121 Query: 485 QLGELAENVAGGVDVYTLYQPLGVGAGITAFNFPVMLPCFMFPIAVACGNTFVLKPSEQD 544 QLGE AEN A G+DVYTL QPLGV AGITAFNFPVMLPCFMFPIAVACGN+FVLKPSEQD Sbjct: 122 QLGEYAENAASGIDVYTLIQPLGVCAGITAFNFPVMLPCFMFPIAVACGNSFVLKPSEQD 181 Query: 545 PTSSLFLVELANQAGLPPGVLNVVHGGPDVANMICDHPDIKAVSFIGSTHVGTHIYRRAS 604 PT+SLFL +LA +AGLPPGVLNVVHGGPD AN +C+HPDIKAVSFIGST VGT IY RAS Sbjct: 182 PTASLFLAQLALEAGLPPGVLNVVHGGPDTANGLCEHPDIKAVSFIGSTRVGTEIYNRAS 241 Query: 605 EAGKRAQCMMGAKNHCIVLPDAPKDQAINNLLGAAFGAAGQRCMANSVVVLVGQTREWIP 664 AGKR Q MMGAKNHC++LPDA + A+N L+GAAFGAAGQRCMA+SV VLVG+ R W+P Sbjct: 242 AAGKRCQSMMGAKNHCVILPDADPEVALNQLVGAAFGAAGQRCMASSVAVLVGEARNWLP 301 Query: 665 EIVERSKAMKVGPGTDRKADVGPLVSKAAKERVERLIASGVEQGAKLLLDGRNCKVAGSE 724 + VERSK +KV GTDR+AD+GPLVS AK+RVE LI GV++GAKLLLDGRN KV+G E Sbjct: 302 DFVERSKKLKVNSGTDREADLGPLVSPNAKKRVESLIQKGVDEGAKLLLDGRNLKVSGFE 361 Query: 725 NGNFVGPTVFTGVKPEMDIYAQEIFGPAMCIVELDTLDEAIAFINANPNGNGTSIFTSSG 784 GNFVGPT+F GV EM IY +EIFGP +C V ++TL++A+AFIN NPNGNG ++FT G Sbjct: 362 QGNFVGPTIFDGVNEEMTIYTEEIFGPVLCCVGVETLEDAVAFINRNPNGNGVALFTQDG 421 Query: 785 YAARKFQNEIDVGQVGINVPIPVPVAYFSFTGSRASKLGDLGPNGKQAVTFWTQTKTVTA 844 AAR FQN IDVGQVGINVPIPVPVA+FSFTGSR SKLGDLGPNGKQAV FWTQTKTVTA Sbjct: 422 GAARYFQNNIDVGQVGINVPIPVPVAWFSFTGSRGSKLGDLGPNGKQAVQFWTQTKTVTA 481 Query: 845 RWYAPDEEAGQVNTTITLK 863 RW A A VNTTI+++ Sbjct: 482 RWSA---HAKTVNTTISMR 497