BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3690.p (297 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776462.1| 3-hydroxyisobutyrate dehydrogenase [Herbaspi... 494 e-138 ref|YP_786279.1| 3-hydroxyisobutyrate dehydrogenase [Bordetella ... 316 2e-84 ref|YP_001631119.1| 3-hydroxyisobutyrate dehydrogenase [Bordetel... 316 3e-84 ref|ZP_06687483.1| 3-hydroxyisobutyrate dehydrogenase [Achromoba... 307 1e-81 gb|EGP44106.1| 3-hydroxyisobutyrate dehydrogenase [Achromobacter... 307 2e-81 >ref|YP_003776462.1| 3-hydroxyisobutyrate dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ64554.1| 3-hydroxyisobutyrate dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 297 Score = 494 bits (1271), Expect = e-138, Method: Composition-based stats. Identities = 282/297 (94%), Positives = 290/297 (97%) Query: 1 MSANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKAD 60 MSANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKAD Sbjct: 1 MSANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKAD 60 Query: 61 VVITMLPASRHVESIYLGDKGILANIKPGTLLIDCSTIAPESARMVAAAALEKGYTMLDA 120 VVITMLPASRHVES+YLG+ G+LA+ KPGTLLIDCSTIAPE+AR VAAAA +G+ MLDA Sbjct: 61 VVITMLPASRHVESLYLGEAGVLASAKPGTLLIDCSTIAPEAARKVAAAAKARGFEMLDA 120 Query: 121 PVSGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLG 180 PVSGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLG Sbjct: 121 PVSGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLG 180 Query: 181 TLMIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMETAPASKGYAGGF 240 LMIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMETAPASKGYAGGF Sbjct: 181 ILMIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMETAPASKGYAGGF 240 Query: 241 GVDLMLKDLGLAVENALATNCAIPLGSTARNLYDIHSMNGAGKLDFSSIFNMLGKAQ 297 GVDLMLKDLGLAVENALATNCAIPLG+TARNLYDIHSMNGAGKLDFSSIFNMLGKAQ Sbjct: 241 GVDLMLKDLGLAVENALATNCAIPLGATARNLYDIHSMNGAGKLDFSSIFNMLGKAQ 297 >ref|YP_786279.1| 3-hydroxyisobutyrate dehydrogenase [Bordetella avium 197N] emb|CAJ49369.1| 3-hydroxyisobutyrate dehydrogenase [Bordetella avium 197N] Length = 294 Score = 316 bits (810), Expect = 2e-84, Method: Composition-based stats. Identities = 190/290 (65%), Positives = 228/290 (78%), Gaps = 3/290 (1%) Query: 3 ANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKADVV 62 ++I FIGLGNMG PMA NLVKAG S+ DL+ +V +L E G + + AAV AD+V Sbjct: 2 SSIAFIGLGNMGAPMALNLVKAGHSLVVFDLLADAVQRLTEAGARAATSASAAVDGADIV 61 Query: 63 ITMLPASRHVESIYLGDKGILANIKPGTLLIDCSTIAPESARMVAAAALEKGYTMLDAPV 122 ITMLPAS+HVE +YL ++ +L IK G L+IDCSTIAP+SAR VAAAA +G M+DAPV Sbjct: 62 ITMLPASKHVEHLYL-EQDLLGKIKAGALVIDCSTIAPDSARKVAAAATARGLEMIDAPV 120 Query: 123 SGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLGTL 182 SGGT GA AGTLTF+VGG+ A E A+P L+KMGK I+HAGE+GSGQ K+CNNMLLG L Sbjct: 121 SGGTGGAVAGTLTFIVGGA--ALERARPVLEKMGKNIFHAGEAGSGQVAKICNNMLLGIL 178 Query: 183 MIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMETAPASKGYAGGFGV 242 M GTSEA+ LG+ANG+DPKVLS+I++KSSGRNW E+YNP PGVM APAS GYAGGFGV Sbjct: 179 MAGTSEALALGVANGLDPKVLSDIIAKSSGRNWATELYNPWPGVMPHAPASHGYAGGFGV 238 Query: 243 DLMLKDLGLAVENALATNCAIPLGSTARNLYDIHSMNGAGKLDFSSIFNM 292 DLMLKDLGLA E AL + +IPLG ARNLY +HS G+G+LDFSSI N+ Sbjct: 239 DLMLKDLGLAAEAALGSRSSIPLGELARNLYSLHSNGGSGRLDFSSIVNL 288 >ref|YP_001631119.1| 3-hydroxyisobutyrate dehydrogenase [Bordetella petrii DSM 12804] emb|CAP42851.1| 3-hydroxyisobutyrate dehydrogenase [Bordetella petrii] Length = 295 Score = 316 bits (809), Expect = 3e-84, Method: Composition-based stats. Identities = 187/290 (64%), Positives = 230/290 (79%), Gaps = 1/290 (0%) Query: 3 ANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKADVV 62 ++I FIGLGNMG PMA NL+KAG S++ DLV A+V L + G + + AV A+VV Sbjct: 2 SSIAFIGLGNMGAPMAHNLIKAGHSLTVFDLVPAAVQGLSDAGARAAGSAAEAVRGAEVV 61 Query: 63 ITMLPASRHVESIYLGDKGILANIKPGTLLIDCSTIAPESARMVAAAALEKGYTMLDAPV 122 I+MLPAS+HVE++YL D +L++I P L+I+CSTIAP+SAR VAAAA +G M+DAPV Sbjct: 62 ISMLPASKHVEALYL-DNDLLSSIDPSALVIECSTIAPDSARKVAAAAQARGLAMIDAPV 120 Query: 123 SGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLGTL 182 SGGT GA AGTLTF+VGG +A + A P LQ MGK I+HAG +G+GQ K+CNNMLLG L Sbjct: 121 SGGTGGAAAGTLTFIVGGEPDALQRAMPVLQNMGKNIFHAGTAGAGQVAKICNNMLLGIL 180 Query: 183 MIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMETAPASKGYAGGFGV 242 M GTSEA+ LG+ANG+DPKVLS+I++KSSGRNW E+YNP PGVME APASKGYAGGFGV Sbjct: 181 MAGTSEALALGVANGLDPKVLSDIIAKSSGRNWATELYNPWPGVMEHAPASKGYAGGFGV 240 Query: 243 DLMLKDLGLAVENALATNCAIPLGSTARNLYDIHSMNGAGKLDFSSIFNM 292 DLMLKDLGLA E+AL++ +IPLG ARNLY +HS G+GKLDFSSI N+ Sbjct: 241 DLMLKDLGLAAESALSSRSSIPLGELARNLYSLHSTGGSGKLDFSSIVNL 290 >ref|ZP_06687483.1| 3-hydroxyisobutyrate dehydrogenase [Achromobacter piechaudii ATCC 43553] gb|EFF75583.1| 3-hydroxyisobutyrate dehydrogenase [Achromobacter piechaudii ATCC 43553] Length = 296 Score = 307 bits (787), Expect = 1e-81, Method: Composition-based stats. Identities = 188/295 (63%), Positives = 230/295 (77%), Gaps = 1/295 (0%) Query: 3 ANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKADVV 62 ++I FIGLGNMG PMA NLVKAG S++ DLV A+V L + G + A + AV ADVV Sbjct: 2 SSIAFIGLGNMGAPMALNLVKAGHSLTVFDLVPAAVKLLTDAGARAAASAAEAVKGADVV 61 Query: 63 ITMLPASRHVESIYLGDKGILANIKPGTLLIDCSTIAPESARMVAAAALEKGYTMLDAPV 122 ++MLPAS+HVE +YL D+ +L +I L+I+CSTIAP+SAR VA AA +G M+DAPV Sbjct: 62 VSMLPASKHVEGLYL-DQDLLGHISSSALVIECSTIAPDSARKVAQAAEVRGIAMIDAPV 120 Query: 123 SGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLGTL 182 SGGT GA AGTLTF+VGG A E A+P L+KMGK I+HAG +G+GQ K+CNNMLLG L Sbjct: 121 SGGTGGAAAGTLTFIVGGQAAALERARPVLEKMGKNIFHAGPAGAGQVAKICNNMLLGIL 180 Query: 183 MIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMETAPASKGYAGGFGV 242 M GTSEA+ LG+ANG+DPKVLS+I++KSSGRNW E+YNP PGVM+ APASKGYAGGFGV Sbjct: 181 MAGTSEALALGVANGLDPKVLSDIIAKSSGRNWATELYNPWPGVMDHAPASKGYAGGFGV 240 Query: 243 DLMLKDLGLAVENALATNCAIPLGSTARNLYDIHSMNGAGKLDFSSIFNMLGKAQ 297 DLMLKDLGLA E AL+ +IPLG ARNLY +HS G+GKLDFSSI N++ + Q Sbjct: 241 DLMLKDLGLAAEAALSARASIPLGELARNLYSLHSAGGSGKLDFSSIVNLVKREQ 295 >gb|EGP44106.1| 3-hydroxyisobutyrate dehydrogenase [Achromobacter xylosoxidans AXX-A] Length = 296 Score = 307 bits (786), Expect = 2e-81, Method: Composition-based stats. Identities = 189/295 (64%), Positives = 230/295 (77%), Gaps = 1/295 (0%) Query: 3 ANIVFIGLGNMGLPMAQNLVKAGFSVSGHDLVKASVDKLVEVGGKTEADSMAAVAKADVV 62 ++I FIGLGNMG PMA NLVKAG S++ DLV A+V L + G K+ A + AV A+VV Sbjct: 2 SSIAFIGLGNMGSPMALNLVKAGHSLTVFDLVPAAVKVLTDAGAKSAASAAEAVKGAEVV 61 Query: 63 ITMLPASRHVESIYLGDKGILANIKPGTLLIDCSTIAPESARMVAAAALEKGYTMLDAPV 122 I+MLPAS+HVE +YL D+ +L I L+I+CSTIAP+SAR VA AA +G M+DAPV Sbjct: 62 ISMLPASKHVEGLYL-DQDLLGKIPASALVIECSTIAPDSARKVAQAAEVRGIAMIDAPV 120 Query: 123 SGGTNGATAGTLTFMVGGSKEAFEAAQPYLQKMGKAIYHAGESGSGQTVKVCNNMLLGTL 182 SGGT GA AGTLTF+VGG A E A+P L+KMGK I+HAG +G+GQ K+CNNMLLG L Sbjct: 121 SGGTGGAAAGTLTFIVGGQPAALERARPVLEKMGKNIFHAGPAGAGQVAKICNNMLLGIL 180 Query: 183 MIGTSEAIRLGMANGMDPKVLSEIMSKSSGRNWTLEVYNPCPGVMETAPASKGYAGGFGV 242 M GTSEA+ LG+ANG+DPKVLS+I++KSSGRNW E+YNP PGVME APASKGYAGGFGV Sbjct: 181 MAGTSEALALGVANGLDPKVLSDIIAKSSGRNWATELYNPWPGVMEHAPASKGYAGGFGV 240 Query: 243 DLMLKDLGLAVENALATNCAIPLGSTARNLYDIHSMNGAGKLDFSSIFNMLGKAQ 297 DLMLKDLGLA E AL+ +IPLG ARNLY +HS G+G+LDFSSI N++ + Q Sbjct: 241 DLMLKDLGLAAEAALSARASIPLGELARNLYSLHSAGGSGRLDFSSIVNLVKREQ 295