BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3673.p (488 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776449.1| cobalt/zinc/cadmium resistance two component... 726 0.0 ref|YP_004750845.1| sensor kinase protein [Collimonas fungivoran... 505 e-141 ref|NP_891077.1| sensor kinase [Bordetella bronchiseptica RB50] ... 489 e-136 ref|YP_003607271.1| multi-sensor signal transduction histidine k... 473 e-131 ref|ZP_03265150.1| heavy metal sensor signal transduction histid... 464 e-128 >ref|YP_003776449.1| cobalt/zinc/cadmium resistance two component transmembrane sensor histidine kinase [Herbaspirillum seropedicae SmR1] gb|ADJ64541.1| cobalt/zinc/cadmium resistance two component transmembrane sensor histidine kinase protein [Herbaspirillum seropedicae SmR1] Length = 475 Score = 726 bits (1875), Expect = 0.0, Method: Composition-based stats. Identities = 407/474 (85%), Positives = 431/474 (90%), Gaps = 3/474 (0%) Query: 1 MNAAATSVRGWTLTSRVTALFALMTALVVTCLGFYLDRAAGVALSQRADQALIGRVEHFR 60 M+ +V GWTLT+RVTALFALMT+LVVT LGFYLDR+AG ALSQRADQALIGRVEHFR Sbjct: 1 MSPPTPAVGGWTLTTRVTALFALMTSLVVTGLGFYLDRSAGQALSQRADQALIGRVEHFR 60 Query: 61 NLMHDLYNVEQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLQPPDMTPLPVGR 120 NLMHDLYNVEQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHL PP MTPLPVG Sbjct: 61 NLMHDLYNVEQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLVPPAMTPLPVGS 120 Query: 121 PVSSASLQTSVRPDGVKVRWVSALADVGKGGAGGDRVEIVAAYVMVQESRMMHSYRWRIA 180 PVSSASL+TS R DGV+VRWVSALADVGKGG D VEIVAAYVMVQE+RMM SYRWRIA Sbjct: 121 PVSSASLRTSQRADGVRVRWVSALADVGKGG---DTVEIVAAYVMVQEARMMRSYRWRIA 177 Query: 181 GAAGAAILLTSLLGFLLLRRGLQPLEAMSQRAAQITPDRLSTRLEQEGMPAELRRVALSF 240 GAA AA++LT+LLGFLLLRRGLQPLEAMSQRAAQITPD LS RL+QEGMPAELRRVALSF Sbjct: 178 GAAAAAVVLTALLGFLLLRRGLQPLEAMSQRAAQITPDHLSARLDQEGMPAELRRVALSF 237 Query: 241 NAMLDRLEAGYDHLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSLEEYEQLLESNVEEL 300 NAMLDRLEAGY HLAQFSGDLAHEIRTPINVLMGQSQVALGQRRS EEYEQ+LESNVEEL Sbjct: 238 NAMLDRLEAGYAHLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSPEEYEQVLESNVEEL 297 Query: 301 QRLSRIVENILFLAQADHATLAVECSALDLHEELGKVTDYFEGIADERGLRFELQAQGTC 360 QRLSRIVENILFLAQADHA LAVE +ALDL EELG++TDYFEGIADERG+RF++QA G C Sbjct: 298 QRLSRIVENILFLAQADHAALAVERNALDLAEELGRITDYFEGIADERGMRFDVQAAGQC 357 Query: 361 HANRDMWRRAVNNLVINAVRYGEADSVIRIQAENDASGSRILVDNRCEGVTPHAMARMFD 420 AN MWRR V+NLVINAVRYG A+S IRI AE+D GSRI+V+NR E VT AMARMFD Sbjct: 358 QANLIMWRRVVSNLVINAVRYGRAESTIRILAESDGEGSRIMVENRSEDVTAQAMARMFD 417 Query: 421 RFYRGDRSRSAFTESNGLGLAIVKAIMALHRGTAAVECPQPGWIRFSLFFPSAA 474 RFYRGDRSRSAFTESNGLGLAIVKAIMALH GTAAVECP PGWIRFSL FPSAA Sbjct: 418 RFYRGDRSRSAFTESNGLGLAIVKAIMALHGGTAAVECPAPGWIRFSLRFPSAA 471 >ref|YP_004750845.1| sensor kinase protein [Collimonas fungivorans Ter331] gb|AEK60022.1| sensor kinase protein [Collimonas fungivorans Ter331] Length = 470 Score = 505 bits (1301), Expect = e-141, Method: Composition-based stats. Identities = 272/466 (58%), Positives = 345/466 (74%), Gaps = 3/466 (0%) Query: 9 RGWTLTSRVTALFALMTALVVTCLGFYLDRAAGVALSQRADQALIGRVEHFRNLMHDLYN 68 R +LT+RVT LFAL+ +V LG YL + AL RAD +LIG+VEHFR+L+HDLYN Sbjct: 5 RRQSLTARVTFLFALIACAIVATLGMYLYSSTRQALETRADYSLIGKVEHFRHLLHDLYN 64 Query: 69 VEQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLQPPDMTPLPVGRPVSSASLQ 128 V+QME P LFE+M+G+EQDV IF G+APF++ NPDH+ PP MTP + +P++ A L Sbjct: 65 VKQMEDSPTLFETMLGSEQDVLIFAYPGQAPFVRVNPDHMTPPPMTPQSLDQPLTLAQLH 124 Query: 129 TSVRPDGVKVRWVSALADVGKGGAGGDRVEIVAAYVMVQESRMMHSYRWRIAGAAGAAIL 188 VR DGV+VRWVSALADVG G +V I A+VM QES ++ Y W++ GAA A+L Sbjct: 125 AGVRADGVRVRWVSALADVG---GDGTQVVITGAHVMTQESHILARYYWQVIGAAAVAVL 181 Query: 189 LTSLLGFLLLRRGLQPLEAMSQRAAQITPDRLSTRLEQEGMPAELRRVALSFNAMLDRLE 248 L +LLGFL+L+RG PL AM+ RAA+++P ++ RL +E P ELRR+A SFNAMLDRL Sbjct: 182 LAALLGFLVLKRGFLPLTAMACRAAEVSPTNIAIRLREEDAPHELRRLAASFNAMLDRLA 241 Query: 249 AGYDHLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSLEEYEQLLESNVEELQRLSRIVE 308 GY+HL+QFS DLAHEIRTPI LMGQ+QV LGQ R+ EY+Q+LESN+EELQRLSRIVE Sbjct: 242 DGYEHLSQFSADLAHEIRTPIGALMGQTQVTLGQVRNAAEYQQVLESNLEELQRLSRIVE 301 Query: 309 NILFLAQADHATLAVECSALDLHEELGKVTDYFEGIADERGLRFELQAQGTCHANRDMWR 368 NILFLA ADHA LAVE + L L +EL K+ DYFEG+A+ERG+R E+ A G A+ MWR Sbjct: 302 NILFLAHADHAGLAVEKTPLVLADELHKIADYFEGVAEERGIRLEVDASGKVQASPVMWR 361 Query: 369 RAVNNLVINAVRYGEADSVIRIQAENDASGSRILVDNRCEGVTPHAMARMFDRFYRGDRS 428 RAV+NLV+NAVRY S +R+ A G + V+N+ + + P + R+FDRFYRGD+S Sbjct: 362 RAVSNLVVNAVRYAAPGSTVRLSGRPQAQGIDVAVENQGDPIPPEQLERLFDRFYRGDQS 421 Query: 429 RSAFTESNGLGLAIVKAIMALHRGTAAVECPQPGWIRFSLFFPSAA 474 RS +TESNGLGLAIV+AIM +H G+A V C + G IRFSL+FP A Sbjct: 422 RSEYTESNGLGLAIVRAIMLVHGGSAEVACSREGLIRFSLYFPEGA 467 >ref|NP_891077.1| sensor kinase [Bordetella bronchiseptica RB50] emb|CAE34906.1| sensor kinase protein [Bordetella bronchiseptica RB50] Length = 471 Score = 489 bits (1258), Expect = e-136, Method: Composition-based stats. Identities = 277/467 (59%), Positives = 341/467 (73%), Gaps = 6/467 (1%) Query: 8 VRGWTL---TSRVTALFALMTALVVTCLGFYLDRAAGVALSQRADQALIGRVEHFRNLMH 64 +R WTL T R FA+++ LVV+ LG YL +A AL RAD L+GRVE FRN++H Sbjct: 1 MRRWTLDSLTVRTALSFAVVSCLVVSGLGLYLYSSARQALETRADYTLVGRVERFRNMLH 60 Query: 65 DLYNVEQMEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLQPPDMTPLPVGRPVSS 124 DLYN+ QMEQRPALFESM+GNE+DVRIFRR GEAPFI NPD + PP MTP+PVGR ++ Sbjct: 61 DLYNIRQMEQRPALFESMLGNERDVRIFRRLGEAPFIAVNPDGMAPPPMTPVPVGRDITI 120 Query: 125 ASLQTSVRPDGVKVRWVSALADVGKGGAGGDRVEIVAAYVMVQESRMMHSYRWRIAGAAG 184 SL + RPDGV+VRWVSALA++G+ G VE+ AAYVM QES M+ +Y R+ A Sbjct: 121 ESLHSGERPDGVRVRWVSALAEIGEDGG---TVEVTAAYVMKQESNMLSAYLLRVVVAIV 177 Query: 185 AAILLTSLLGFLLLRRGLQPLEAMSQRAAQITPDRLSTRLEQEGMPAELRRVALSFNAML 244 LLT+L+G+ LL RG +PL AMS RA +I+P L+ RL + PAELR +A FNAML Sbjct: 178 LTTLLTALIGYALLVRGFRPLAAMSARATEISPANLAARLPERDAPAELRGLARQFNAML 237 Query: 245 DRLEAGYDHLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSLEEYEQLLESNVEELQRLS 304 DRL+AGY+HL+QFS DLAHEIRTPINVLMGQ+QVAL Q R +EYE LLESN+EEL RL+ Sbjct: 238 DRLQAGYEHLSQFSADLAHEIRTPINVLMGQTQVALRQPRGADEYELLLESNLEELARLA 297 Query: 305 RIVENILFLAQADHATLAVECSALDLHEELGKVTDYFEGIADERGLRFELQAQGTCHANR 364 IVENILFL++A+H AVE + L EL K+ +YFEG A ERG+RF ++A G C AN Sbjct: 298 HIVENILFLSRANHDGAAVEYAWLAQSAELAKIAEYFEGPAQERGMRFAIEASGQCRANP 357 Query: 365 DMWRRAVNNLVINAVRYGEADSVIRIQAENDASGSRILVDNRCEGVTPHAMARMFDRFYR 424 MWRRAVNNLV+NAVRYG DS I ++A DA+G+ I+V+N V+ RMF RFYR Sbjct: 358 IMWRRAVNNLVVNAVRYGHPDSCILLRAGADANGATIVVENMGAPVSQEEADRMFGRFYR 417 Query: 425 GDRSRSAFTESNGLGLAIVKAIMALHRGTAAVECPQPGWIRFSLFFP 471 D+SR+A TESNGLGLAIV AIM +H G+A+ G IRF+L FP Sbjct: 418 SDKSRTASTESNGLGLAIVSAIMRMHGGSASATALDDGRIRFTLRFP 464 >ref|YP_003607271.1| multi-sensor signal transduction histidine kinase [Burkholderia sp. CCGE1002] gb|ADG17760.1| multi-sensor signal transduction histidine kinase [Burkholderia sp. CCGE1002] Length = 466 Score = 473 bits (1217), Expect = e-131, Method: Composition-based stats. Identities = 246/462 (53%), Positives = 321/462 (69%), Gaps = 3/462 (0%) Query: 12 TLTSRVTALFALMTALVVTCLGFYLDRAAGVALSQRADQALIGRVEHFRNLMHDLYNVEQ 71 +L +R T LFAL+ V+ LG Y +A VAL +RAD L GRVEHF ++HDLY+V + Sbjct: 8 SLIARTTLLFALIACAVIGSLGAYFYHSAEVALQRRADVVLSGRVEHFSRIVHDLYSVSE 67 Query: 72 MEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLQPPDMTPLPVGRPVSSASLQTSV 131 +++RP LFE+M+G E+DV IFRR GEAPF+ NP L PD+ +P G P + ++ + Sbjct: 68 LKKRPLLFETMLGAEEDVLIFRRPGEAPFVDVNPGGLAVPDLPVMPAGNPPRATDVRRTR 127 Query: 132 RPDGVKVRWVSALADVGKGGAGGDRVEIVAAYVMVQESRMMHSYRWRIAGAAGAAILLTS 191 PDGV V W A A + GA VE++A + M E RM+ YR RI A +L + Sbjct: 128 LPDGVPVHWAIATATAREDGA---EVEVIAGHPMTHEMRMLAEYRNRIVLATLTGMLAAT 184 Query: 192 LLGFLLLRRGLQPLEAMSQRAAQITPDRLSTRLEQEGMPAELRRVALSFNAMLDRLEAGY 251 LL + +LRR L+P+ ++ RAAQI+P L+ RL+ E P ELR++ +FNAMLDRL GY Sbjct: 185 LLAYCVLRRALRPVREIAARAAQISPTNLAVRLDDEAAPVELRQLTHAFNAMLDRLADGY 244 Query: 252 DHLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSLEEYEQLLESNVEELQRLSRIVENIL 311 L QFS DLAHEIRTP+ L+GQ+QVAL Q R +EY+QLLESN+EEL RLS I ENIL Sbjct: 245 QRLQQFSADLAHEIRTPVGALVGQTQVALAQPREPDEYQQLLESNLEELNRLSHIAENIL 304 Query: 312 FLAQADHATLAVECSALDLHEELGKVTDYFEGIADERGLRFELQAQGTCHANRDMWRRAV 371 FLA ADHA L++E +DLH EL ++ DYFEG+ADERG+RFE+ A G AN + RRA+ Sbjct: 305 FLAHADHAALSIERQPVDLHGELVRIADYFEGLADERGMRFEVDAAGIASANPMLCRRAI 364 Query: 372 NNLVINAVRYGEADSVIRIQAENDASGSRILVDNRCEGVTPHAMARMFDRFYRGDRSRSA 431 NNLV+NAVRYG D+++R++ D +G+ + V+N E + + R+FDRFYRGD +RSA Sbjct: 365 NNLVVNAVRYGSGDTIVRLRGAQDQAGALVTVENEGEPIPAAQLDRLFDRFYRGDAARSA 424 Query: 432 FTESNGLGLAIVKAIMALHRGTAAVECPQPGWIRFSLFFPSA 473 FTESNGLGLAIVKAIM LH G+A V CP PG +RF L FP+A Sbjct: 425 FTESNGLGLAIVKAIMHLHGGSARVVCPLPGVVRFELRFPAA 466 >ref|ZP_03265150.1| heavy metal sensor signal transduction histidine kinase [Burkholderia sp. H160] gb|EEA03228.1| heavy metal sensor signal transduction histidine kinase [Burkholderia sp. H160] Length = 466 Score = 464 bits (1194), Expect = e-128, Method: Composition-based stats. Identities = 243/462 (52%), Positives = 318/462 (68%), Gaps = 3/462 (0%) Query: 12 TLTSRVTALFALMTALVVTCLGFYLDRAAGVALSQRADQALIGRVEHFRNLMHDLYNVEQ 71 +L +R T LFAL+ +V+ LG Y +A V+L +RAD L GRV HF ++HDLY+V + Sbjct: 8 SLIARTTLLFALIACVVIGSLGAYFYHSAEVSLQRRADVVLSGRVGHFSRIVHDLYSVSE 67 Query: 72 MEQRPALFESMMGNEQDVRIFRRQGEAPFIQSNPDHLQPPDMTPLPVGRPVSSASLQTSV 131 +++RP LFE+M+G E+DV IFRR GEAPF+ NP L PD+ G +A ++ + Sbjct: 68 LKKRPLLFETMLGAEEDVLIFRRPGEAPFVDVNPARLAVPDLQDAAAGNLPRAADIRQTR 127 Query: 132 RPDGVKVRWVSALADVGKGGAGGDRVEIVAAYVMVQESRMMHSYRWRIAGAAGAAILLTS 191 PDGV V W A A + G VE++A + M QE RM+ +YR RI A +L + Sbjct: 128 LPDGVPVHWAIATA---RSREDGTEVEVIAGHPMTQEMRMLAAYRNRIVLATLTGMLAAT 184 Query: 192 LLGFLLLRRGLQPLEAMSQRAAQITPDRLSTRLEQEGMPAELRRVALSFNAMLDRLEAGY 251 LL + +LRR L+P+ ++ RAAQI+P L+ RL+ E P ELR++ +FNAMLDRL GY Sbjct: 185 LLAYFVLRRALRPVREIATRAAQISPANLAVRLDDEAAPVELRQLTQAFNAMLDRLADGY 244 Query: 252 DHLAQFSGDLAHEIRTPINVLMGQSQVALGQRRSLEEYEQLLESNVEELQRLSRIVENIL 311 L QFS DLAHEIRTP+ L+GQ+QVAL Q R +EY+QLLESN+EEL RLS I ENIL Sbjct: 245 QRLQQFSADLAHEIRTPVGALVGQTQVALAQPREPDEYQQLLESNLEELSRLSHIAENIL 304 Query: 312 FLAQADHATLAVECSALDLHEELGKVTDYFEGIADERGLRFELQAQGTCHANRDMWRRAV 371 FLA ADHA L++E +DL EL ++ DYFEG+ADERG+RFE+ A G AN +WRRA+ Sbjct: 305 FLAHADHAALSIERQPVDLQGELVRIADYFEGLADERGMRFEVDATGVVSANPMLWRRAI 364 Query: 372 NNLVINAVRYGEADSVIRIQAENDASGSRILVDNRCEGVTPHAMARMFDRFYRGDRSRSA 431 NNLV NAVRYG DS++R++ D +G+ + V+N + + + R+FDRFYRGD +RSA Sbjct: 365 NNLVANAVRYGAGDSIVRLRGAQDEAGALVTVENEGDPIPTAQLDRLFDRFYRGDAARSA 424 Query: 432 FTESNGLGLAIVKAIMALHRGTAAVECPQPGWIRFSLFFPSA 473 FTESNGLGLAIVKAIM LH G+A V CP PG +RF L FP A Sbjct: 425 FTESNGLGLAIVKAIMHLHGGSAQVVCPLPGVVRFELRFPGA 466