BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3637.p (246 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776422.1| 2-C-methyl-D-erythritol 4-phosphate cytidyly... 382 e-104 ref|YP_004752446.1| 2-C-methyl-D-erythritol 4-phosphate cytidyly... 260 2e-67 ref|YP_001100186.1| 4-diphosphocytidyl-2C-methyl-D-erythritol sy... 258 5e-67 ref|YP_001353099.1| 2-C-methyl-D-erythritol 4-phosphate cytidyly... 245 4e-63 ref|ZP_04576297.1| bifunctional enzyme ispD/ispF [Oxalobacter fo... 216 2e-54 >ref|YP_003776422.1| 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [Herbaspirillum seropedicae SmR1] gb|ADJ64514.1| 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase protein [Herbaspirillum seropedicae SmR1] Length = 254 Score = 382 bits (980), Expect = e-104, Method: Composition-based stats. Identities = 209/234 (89%), Positives = 221/234 (94%) Query: 12 RHFALIPAAGVGARMGGQIPKQYMPLAGLPMLLHALQTFAVHARIAHTFVVVSAEDGWID 71 RHFALIPAAGVGARMGGQIPKQY+PLAG PMLLHALQ FA HARIAHTFVVVSAEDGWID Sbjct: 20 RHFALIPAAGVGARMGGQIPKQYLPLAGQPMLLHALQRFAAHARIAHTFVVVSAEDGWID 79 Query: 72 SLMTPDLLQRVSILRVGGPTRQDSVFNGLNAIRDRVADADRVLVHDAARPGLDAPLLDRL 131 +LMTP L QRVSILRVGGPTRQDSVFNGLNA+R+++ADAD VLVHDAARPG+DA L+DRL Sbjct: 80 ALMTPALRQRVSILRVGGPTRQDSVFNGLNALREQLADADWVLVHDAARPGVDAALIDRL 139 Query: 132 LDALADDEIGGLLAVPVVDTLKRGDGGAPARSQETVPRAGLWAAQTPQMFPYALLQRALH 191 LDALA DE+GGLLA+PVVDTLKRGDG + RSQ+TVPRAGLWAAQTPQMFPYALL RAL Sbjct: 140 LDALAQDEVGGLLALPVVDTLKRGDGASSPRSQQTVPRAGLWAAQTPQMFPYALLHRALR 199 Query: 192 QAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFLKGPH 245 QAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFLKGPH Sbjct: 200 QAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFLKGPH 253 >ref|YP_004752446.1| 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [Collimonas fungivorans Ter331] gb|AEK61623.1| 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [Collimonas fungivorans Ter331] Length = 253 Score = 260 bits (664), Expect = 2e-67, Method: Composition-based stats. Identities = 151/243 (62%), Positives = 176/243 (72%), Gaps = 9/243 (3%) Query: 3 PSQSASSPPRHFALIPAAGVGARMGGQIPKQYMPLAGLPMLLHALQTFAVHARIAHTFVV 62 P + +P R+FALIPAAGVGAR+G IPKQYM LAG PML+H L TFA + I+H +VV Sbjct: 15 PLRLCMNPSRYFALIPAAGVGARIGADIPKQYMQLAGEPMLMHVLDTFAEASAISHVYVV 74 Query: 63 VSAEDGWIDSLMT--PDLLQRVSILRVGGPTRQDSVFNGLNAIRDRVADADRVLVHDAAR 120 VSA+DG+I LM P L RV++L GGP R+DSV NGL AIR++ D D VLVHDAAR Sbjct: 75 VSADDGYIADLMAAAPHLQGRVTVLFDGGPNRRDSVLNGLQAIREQAGDDDWVLVHDAAR 134 Query: 121 PGLDAPLLDRLLDALADDEIGGLLAVPVVDTLKRGDGGAP-ARSQETVPRAGLWAAQTPQ 179 PGL L++RL+ AL DD +GGLLA+PVVDTLKR D AR +TV RA LWAAQTPQ Sbjct: 135 PGLTCALIERLIVALRDDAVGGLLALPVVDTLKRSDKNTQDARVAQTVARAELWAAQTPQ 194 Query: 180 MFPYALLQRALHQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEF 239 MF Y LL RAL A +TD+ASA+E LGL+PRLVEGSPRN KVTL D ALAE Sbjct: 195 MFRYGLLVRALTLA------AAVTDEASAVEQLGLQPRLVEGSPRNFKVTLPHDVALAEM 248 Query: 240 FLK 242 FLK Sbjct: 249 FLK 251 >ref|YP_001100186.1| 4-diphosphocytidyl-2C-methyl-D-erythritol synthase [Herminiimonas arsenicoxydans] emb|CAL62062.1| 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (4-diphosphocytidyl-2C-methyl-D-erythritol synthase) (MEP cytidylyltransferase) (MCT) [Herminiimonas arsenicoxydans] Length = 232 Score = 258 bits (660), Expect = 5e-67, Method: Composition-based stats. Identities = 142/235 (60%), Positives = 172/235 (73%), Gaps = 10/235 (4%) Query: 11 PRHFALIPAAGVGARMGGQIPKQYMPLAGLPMLLHALQTFAVHARIAHTFVVVSAEDGWI 70 PR+FALIPAAG+GAR+GG PKQY+ +AG ML H L TF+ I+HTFVVVSAEDG+I Sbjct: 4 PRYFALIPAAGIGARIGGSTPKQYVSIAGKAMLRHVLDTFSDTVAISHTFVVVSAEDGYI 63 Query: 71 DSLMT--PDLLQRVSILRVGGPTRQDSVFNGLNAIRDRVADADRVLVHDAARPGLDAPLL 128 + +M PD +++LRVGGPTRQ SV NGL+A R+ + D D VLVHDAARPGL+ L+ Sbjct: 64 NDIMAEPPDHHAGITVLRVGGPTRQLSVLNGLHAAREWIGDDDWVLVHDAARPGLNDSLV 123 Query: 129 DRLLDALADDEIGGLLAVPVVDTLKRGDGGAPARSQETVPRAGLWAAQTPQMFPYALLQR 188 D+L+ L DDE+GGLLAVPVVDTLKR D R + TV R LWAAQTPQMFPY LL++ Sbjct: 124 DKLIQTLKDDEVGGLLAVPVVDTLKRMD--ESGRVENTVAREHLWAAQTPQMFPYGLLKK 181 Query: 189 ALHQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFLKG 243 AL QA +TD+A AIE LGL+P+LV G N KVTL +D ALAE +LKG Sbjct: 182 ALEQA------AAVTDEAGAIEALGLKPKLVTGHACNFKVTLPEDVALAELYLKG 230 >ref|YP_001353099.1| 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [Janthinobacterium sp. Marseille] gb|ABR88338.1| 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [Janthinobacterium sp. Marseille] Length = 235 Score = 245 bits (626), Expect = 4e-63, Method: Composition-based stats. Identities = 142/238 (59%), Positives = 169/238 (71%), Gaps = 13/238 (5%) Query: 11 PRHFALIPAAGVGARMGGQIPKQYMPLAGLPMLLHALQTFAVHARIAHTFVVVSAEDGWI 70 PR+FALIPAAGVGARMG +IPKQY+ +AG PML H L TF I HT+VVVSAEDG+I Sbjct: 4 PRYFALIPAAGVGARMGEKIPKQYVQIAGKPMLRHVLDTFCRADVITHTYVVVSAEDGYI 63 Query: 71 DSLMTP-DLLQRVSILRVGGPTRQDSVFNGLNAIRDRV----ADADRVLVHDAARPGLDA 125 D+ M ++LRVGG TR SV NGL A++++V D D VLVHDAARPGL Sbjct: 64 DATMAALHDSSYATVLRVGGATRHQSVLNGLQAMQEQVNEPINDDDWVLVHDAARPGLSI 123 Query: 126 PLLDRLLDALADDEIGGLLAVPVVDTLKRGDGGAPARSQETVPRAGLWAAQTPQMFPYAL 185 L+D+L++ L DDE+GGLLA+PVVDTLKR GA R +TV R LWAAQTPQMF Y L Sbjct: 124 GLIDKLINILQDDEVGGLLAMPVVDTLKR--AGAEGRVDQTVTRDRLWAAQTPQMFRYGL 181 Query: 186 LQRALHQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEFFLKG 243 L++AL QA +TD+ASAIE GL+P+LVEG RN KVTL D ALAE +LKG Sbjct: 182 LRKALEQAT------AVTDEASAIEAQGLQPKLVEGDARNFKVTLPHDVALAELYLKG 233 >ref|ZP_04576297.1| bifunctional enzyme ispD/ispF [Oxalobacter formigenes HOxBLS] gb|EEO27259.1| bifunctional enzyme ispD/ispF [Oxalobacter formigenes HOxBLS] Length = 241 Score = 216 bits (550), Expect = 2e-54, Method: Composition-based stats. Identities = 123/244 (50%), Positives = 161/244 (65%), Gaps = 15/244 (6%) Query: 4 SQSASSPPRHFALIPAAGVGARMGGQIPKQYMPLAGLPMLLHALQTFAVHARIAHTFVVV 63 + +++ PR FALIPAAGVG+RMG PKQY+ L G P+L +AL+ F + I +V++ Sbjct: 5 TNTSAIAPRFFALIPAAGVGSRMGAACPKQYLELLGKPVLRYALEAFGECSEIERIYVLI 64 Query: 64 SAEDGWIDSLMT--PDL-LQRVSILRVGGPTRQDSVFNGLNAIRDRVADADRVLVHDAAR 120 S ED W+D+ + PDL RV LR GG TR+++V NGL+ + A D +LVHDAAR Sbjct: 65 SHEDEWLDAFLASWPDLDTGRVRFLRCGGVTRRETVLNGLHVLFRECAPDDWILVHDAAR 124 Query: 121 PGLDAPLLDRLLDALADDEIGGLLAVPVVDTLKR-GDGGAPARSQETVPRAGLWAAQTPQ 179 PGL L+ RL+ A+ADD+ GGLLA+PVVDT+KR G+ G ETV R GLW AQTPQ Sbjct: 125 PGLTPELIQRLIHAVADDKTGGLLALPVVDTVKRQGNNGL-----ETVSRDGLWLAQTPQ 179 Query: 180 MFPYALLQRALHQAQEQGRLGEITDDASAIEMLGLRPRLVEGSPRNLKVTLAQDAALAEF 239 MF YA+L+ AL ++ G +TD+A A+E + L P LVEG RN K+T D AL E Sbjct: 180 MFRYAILREALEKS------GNVTDEAGAVEAMSLTPHLVEGHLRNTKITRPADLALVEL 233 Query: 240 FLKG 243 FLK Sbjct: 234 FLKA 237