BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3579.p (324 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003774611.1| 4-hydroxy-3-methylbut-2-enyl diphosphate red... 562 e-158 ref|ZP_08275503.1| 4-hydroxy-3-methylbut-2-enyl diphosphate redu... 504 e-141 ref|YP_001354239.1| 4-hydroxy-3-methylbut-2-enyl diphosphate red... 503 e-140 ref|YP_004751891.1| 4-hydroxy-3-methylbut-2-enyl diphosphate red... 501 e-140 gb|ABW82964.1| hydroxymethylbutenyl pyrophosphate reductase [unc... 498 e-139 >ref|YP_003774611.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Herbaspirillum seropedicae SmR1] emb|CAM32604.1| 4-hydroxy-3-methylbu [Herbaspirillum seropedicae] gb|ADJ62703.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase protein [Herbaspirillum seropedicae SmR1] Length = 323 Score = 562 bits (1449), Expect = e-158, Method: Composition-based stats. Identities = 305/322 (94%), Positives = 316/322 (98%) Query: 3 MTMEQAESEILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKG 62 MTM++AESEILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKG Sbjct: 1 MTMDKAESEILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKG 60 Query: 63 AVFIEELADVPAGNTVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREG 122 AVFIEELADVPAG+TVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREG Sbjct: 61 AVFIEELADVPAGSTVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREG 120 Query: 123 REIIMIGHAGHPEVEGTMGQTEAGMHLVETVEDVQRLQVADPELLAYVSQTTLSVDDTAD 182 REIIMIGHAGHPEVEGTMGQTEAGMHLVETVEDVQRLQVADP LLAYVSQTTLSVDDTA+ Sbjct: 121 REIIMIGHAGHPEVEGTMGQTEAGMHLVETVEDVQRLQVADPALLAYVSQTTLSVDDTAE 180 Query: 183 IIAALRARFPAIAEPKKGDICYATTNRQEAVKFMAPQVEVVIVVGSPNSSNSNRLRELAE 242 IIAALR RFPAI+EPKKGDICYATTNRQEAVKFMAPQV+VVIVVGSPNSSNSNRLRELAE Sbjct: 181 IIAALRERFPAISEPKKGDICYATTNRQEAVKFMAPQVDVVIVVGSPNSSNSNRLRELAE 240 Query: 243 KKGVPAFMVDNAALIDPQWVQGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVLDGI 302 KKGV AFMVDNAALIDP W+QGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVL+GI Sbjct: 241 KKGVAAFMVDNAALIDPLWIQGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVLEGI 300 Query: 303 EENVTFPLPKGLGSRTPSAESA 324 EENVTFPLPKGLG+RT +E+A Sbjct: 301 EENVTFPLPKGLGTRTAPSETA 322 >ref|ZP_08275503.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Oxalobacteraceae bacterium IMCC9480] gb|EGF31024.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Oxalobacteraceae bacterium IMCC9480] Length = 317 Score = 504 bits (1299), Expect = e-141, Method: Composition-based stats. Identities = 260/312 (83%), Positives = 286/312 (91%) Query: 8 AESEILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKGAVFIE 67 + EILLAQPRGFCAGVDRAIEIVERAL QFGAPIYVRHEIVHNAYVV+DLR KGA+FIE Sbjct: 3 SNKEILLAQPRGFCAGVDRAIEIVERALIQFGAPIYVRHEIVHNAYVVDDLRTKGAIFIE 62 Query: 68 ELADVPAGNTVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREGREIIM 127 ELADVP G TV+FSAHGVSKA++ EA ERGL +FDATCPLVTKVH+EV KMRR+GREIIM Sbjct: 63 ELADVPTGQTVVFSAHGVSKAVKIEAEERGLRIFDATCPLVTKVHVEVEKMRRDGREIIM 122 Query: 128 IGHAGHPEVEGTMGQTEAGMHLVETVEDVQRLQVADPELLAYVSQTTLSVDDTADIIAAL 187 IGH GHPEVEGTMGQ+E GM+LVET +DV RLQVA P+LLAYVSQTTLSVDDTADIIAAL Sbjct: 123 IGHDGHPEVEGTMGQSEQGMYLVETTDDVARLQVARPDLLAYVSQTTLSVDDTADIIAAL 182 Query: 188 RARFPAIAEPKKGDICYATTNRQEAVKFMAPQVEVVIVVGSPNSSNSNRLRELAEKKGVP 247 + RFP IAEPKKGDICYATTNRQEAVKFMAPQVE+VIVVGSPNSSNSNRLRE+AEKKGVP Sbjct: 183 KQRFPDIAEPKKGDICYATTNRQEAVKFMAPQVELVIVVGSPNSSNSNRLREVAEKKGVP 242 Query: 248 AFMVDNAALIDPQWVQGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVLDGIEENVT 307 +FMVDNA I+P W++G+QRIGVTAGASAPEVLVQAVIDR+K GARSVRVLDG++E+VT Sbjct: 243 SFMVDNAEQIEPAWLEGKQRIGVTAGASAPEVLVQAVIDRLKIFGARSVRVLDGVQEHVT 302 Query: 308 FPLPKGLGSRTP 319 FP+PKGL P Sbjct: 303 FPMPKGLADERP 314 >ref|YP_001354239.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Janthinobacterium sp. Marseille] gb|ABR88744.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Janthinobacterium sp. Marseille] Length = 309 Score = 503 bits (1294), Expect = e-140, Method: Composition-based stats. Identities = 250/306 (81%), Positives = 288/306 (94%) Query: 9 ESEILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKGAVFIEE 68 ++EILLAQPRGFCAGVDRAIEIVERAL +FGAPIYVRHEIVHNAYVV DLR KGA+FIEE Sbjct: 2 DTEILLAQPRGFCAGVDRAIEIVERALTEFGAPIYVRHEIVHNAYVVTDLRNKGAIFIEE 61 Query: 69 LADVPAGNTVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREGREIIMI 128 L DVPAGNTV+FSAHGVSKA+QAEA +RGL VFDATCPLVTKVH+EV KMRR+GREIIMI Sbjct: 62 LDDVPAGNTVVFSAHGVSKAVQAEAEKRGLRVFDATCPLVTKVHIEVEKMRRDGREIIMI 121 Query: 129 GHAGHPEVEGTMGQTEAGMHLVETVEDVQRLQVADPELLAYVSQTTLSVDDTADIIAALR 188 GH GHPEVEGTMGQ E GMHLVETV+DV++LQV +P++++YV+QTTLS+DDTAD+IAAL+ Sbjct: 122 GHDGHPEVEGTMGQIEDGMHLVETVDDVEKLQVRNPDMISYVTQTTLSIDDTADVIAALK 181 Query: 189 ARFPAIAEPKKGDICYATTNRQEAVKFMAPQVEVVIVVGSPNSSNSNRLRELAEKKGVPA 248 +RFP I+EPKK DICYATTNRQEAVKFMAPQV++VIVVGSPNSSNSNRLRE+AEK+GVPA Sbjct: 182 SRFPNISEPKKADICYATTNRQEAVKFMAPQVDLVIVVGSPNSSNSNRLREVAEKRGVPA 241 Query: 249 FMVDNAALIDPQWVQGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVLDGIEENVTF 308 +MVDNA+ IDP W++G++RIG+TAGASAPEVLVQAVIDR+KE GA+SVR L+G+EENV F Sbjct: 242 YMVDNASQIDPDWLRGKRRIGLTAGASAPEVLVQAVIDRLKECGAQSVRTLEGVEENVIF 301 Query: 309 PLPKGL 314 PLPKGL Sbjct: 302 PLPKGL 307 >ref|YP_004751891.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Collimonas fungivorans Ter331] gb|AEK61068.1| 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Collimonas fungivorans Ter331] Length = 316 Score = 501 bits (1289), Expect = e-140, Method: Composition-based stats. Identities = 258/307 (84%), Positives = 282/307 (91%) Query: 9 ESEILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKGAVFIEE 68 ++EILLAQPRGFCAGVDRAIEIVERAL QFGAPIYVRHEIVHNAYVV DLR KGA+FIEE Sbjct: 8 DNEILLAQPRGFCAGVDRAIEIVERALEQFGAPIYVRHEIVHNAYVVADLRNKGAIFIEE 67 Query: 69 LADVPAGNTVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREGREIIMI 128 LADVPAGNTVIFSAHGVSKA+Q EA RGL VFDATCPLVTKVHMEVAKMRREGREI+MI Sbjct: 68 LADVPAGNTVIFSAHGVSKAVQEEAEVRGLKVFDATCPLVTKVHMEVAKMRREGREIVMI 127 Query: 129 GHAGHPEVEGTMGQTEAGMHLVETVEDVQRLQVADPELLAYVSQTTLSVDDTADIIAALR 188 GH GHPEVEGTMGQT GMHLVETV DV+RLQV +P++LAYVSQTTLSVDDTAD+IAAL+ Sbjct: 128 GHEGHPEVEGTMGQTNDGMHLVETVADVERLQVGNPDMLAYVSQTTLSVDDTADVIAALK 187 Query: 189 ARFPAIAEPKKGDICYATTNRQEAVKFMAPQVEVVIVVGSPNSSNSNRLRELAEKKGVPA 248 +FPAI EPKKGDICYATTNRQ+AVKFMAPQV+VVIVVGSPNSSNSNRLRE+AEKKG A Sbjct: 188 QKFPAITEPKKGDICYATTNRQQAVKFMAPQVDVVIVVGSPNSSNSNRLREVAEKKGTVA 247 Query: 249 FMVDNAALIDPQWVQGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVLDGIEENVTF 308 +MVDNA ID W+QG++RIGVTAGASAPE+LVQAVIDR+K GA++VR LDG EENVTF Sbjct: 248 YMVDNAEQIDQAWLQGKRRIGVTAGASAPEILVQAVIDRLKAYGAKNVRTLDGAEENVTF 307 Query: 309 PLPKGLG 315 P+PKGL Sbjct: 308 PMPKGLA 314 >gb|ABW82964.1| hydroxymethylbutenyl pyrophosphate reductase [uncultured bacterium pEAF66] Length = 315 Score = 498 bits (1281), Expect = e-139, Method: Composition-based stats. Identities = 256/307 (83%), Positives = 285/307 (92%) Query: 10 SEILLAQPRGFCAGVDRAIEIVERALAQFGAPIYVRHEIVHNAYVVNDLRAKGAVFIEEL 69 SEILLAQPRGFCAGVDRAIEIVERAL QFGAPIYVRHEIVHNAYVV DLR+KGA+FIE+L Sbjct: 3 SEILLAQPRGFCAGVDRAIEIVERALKQFGAPIYVRHEIVHNAYVVEDLRSKGAIFIEDL 62 Query: 70 ADVPAGNTVIFSAHGVSKAIQAEAAERGLTVFDATCPLVTKVHMEVAKMRREGREIIMIG 129 DVPAGNT++FSAHGVSKA++AEAA RGLT+FDATCPLVTKVH+EVAKMR++G EIIMIG Sbjct: 63 DDVPAGNTLVFSAHGVSKAVRAEAASRGLTIFDATCPLVTKVHVEVAKMRKQGCEIIMIG 122 Query: 130 HAGHPEVEGTMGQTEAGMHLVETVEDVQRLQVADPELLAYVSQTTLSVDDTADIIAALRA 189 H GHPEVEGTMGQT+ GM+LVETVEDV L V +P+ LAYVSQTTLSVDDTADII A++ Sbjct: 123 HDGHPEVEGTMGQTDEGMYLVETVEDVAALSVRNPDNLAYVSQTTLSVDDTADIIQAIKG 182 Query: 190 RFPAIAEPKKGDICYATTNRQEAVKFMAPQVEVVIVVGSPNSSNSNRLRELAEKKGVPAF 249 R+P + EPKKGDICYATTNRQEAVKFMAPQVEVVIVVGSPNSSNSNRLRE+AEKKG PA+ Sbjct: 183 RYPNVIEPKKGDICYATTNRQEAVKFMAPQVEVVIVVGSPNSSNSNRLREVAEKKGTPAY 242 Query: 250 MVDNAALIDPQWVQGRQRIGVTAGASAPEVLVQAVIDRIKEIGARSVRVLDGIEENVTFP 309 MVDNA+ IDPQW+ G+ RIGVTAGASAPEVLVQAVIDR+KE+GARSVR L+G+EE+VTFP Sbjct: 243 MVDNASQIDPQWLVGKLRIGVTAGASAPEVLVQAVIDRLKELGARSVRALEGVEEHVTFP 302 Query: 310 LPKGLGS 316 LPKGL S Sbjct: 303 LPKGLES 309