BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3462.p (420 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776349.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate ... 805 0.0 ref|YP_004752570.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphospha... 741 0.0 ref|YP_001353817.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate ... 722 0.0 ref|YP_001099566.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate ... 719 0.0 ref|ZP_08275723.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphat... 707 0.0 >ref|YP_003776349.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Herbaspirillum seropedicae SmR1] gb|ADJ64441.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase protein [Herbaspirillum seropedicae SmR1] Length = 420 Score = 805 bits (2078), Expect = 0.0, Method: Composition-based stats. Identities = 407/417 (97%), Positives = 413/417 (99%) Query: 1 MSSFPIASGPLARRNSRRVVISHGAREILVGGGAPVMVQSMTNTDTADAIGTAIQIKELA 60 MSS PIASGPL RRNSRRVVISHG REI+VGGGAPVMVQSMTNTDTADAIGTAIQIK+LA Sbjct: 1 MSSSPIASGPLVRRNSRRVVISHGGREIVVGGGAPVMVQSMTNTDTADAIGTAIQIKDLA 60 Query: 61 RAGSEIVRLTVNTPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLTDYPECAQALSK 120 RAGSE+VRLTVNTPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLT+YPECAQALSK Sbjct: 61 RAGSEVVRLTVNTPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLTEYPECAQALSK 120 Query: 121 YRINPGNVGKGAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENAGRAEPW 180 YRINPGNVGKGAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENAGRAEPW Sbjct: 121 YRINPGNVGKGAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENAGRAEPW 180 Query: 181 SAQAVMYEALVTSAIENAQRAEELGMSGDKIILSCKVSGVQDLIAVYRELARRCDYPLHL 240 SAQAVMYEALVTSAIENAQRAEELGM+GDKIILSCKVSGVQDLIAVYRELARRCDYPLHL Sbjct: 181 SAQAVMYEALVTSAIENAQRAEELGMAGDKIILSCKVSGVQDLIAVYRELARRCDYPLHL 240 Query: 241 GLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVVVGQEILQTMGLR 300 GLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVVVGQEILQTMGLR Sbjct: 241 GLTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVVVGQEILQTMGLR 300 Query: 301 KFTPMVIACPGCGRTTSTVFQDLADKIQTFLREQMPVWKGKYPGVEAMNVAVMGCIVNGP 360 KFTPMVIACPGCGRTTSTVFQDLADKIQTFLREQMPVWKGKYPGVEAMNVAVMGCIVNGP Sbjct: 301 KFTPMVIACPGCGRTTSTVFQDLADKIQTFLREQMPVWKGKYPGVEAMNVAVMGCIVNGP 360 Query: 361 GESKHANIGISLPGTGESPAAPVFIDGEKKMTLRGERIAEEFQKVVLEYVESHYGQG 417 GESKHANIGISLPGTGESPAAPVFIDGEKKMTLRGE IAEEFQKVVL+YVESHYGQG Sbjct: 361 GESKHANIGISLPGTGESPAAPVFIDGEKKMTLRGEHIAEEFQKVVLDYVESHYGQG 417 >ref|YP_004752570.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Collimonas fungivorans Ter331] gb|AEK61747.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Collimonas fungivorans Ter331] Length = 500 Score = 741 bits (1914), Expect = 0.0, Method: Composition-based stats. Identities = 369/417 (88%), Positives = 396/417 (94%) Query: 2 SSFPIASGPLARRNSRRVVISHGAREILVGGGAPVMVQSMTNTDTADAIGTAIQIKELAR 61 ++ PI SGP RR SR IS+G R+I+VGGGAPV+VQSMTNTDTADAIGTAIQIK+LAR Sbjct: 83 TNLPIGSGPSVRRLSRGATISYGERKIMVGGGAPVVVQSMTNTDTADAIGTAIQIKDLAR 142 Query: 62 AGSEIVRLTVNTPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLTDYPECAQALSKY 121 AGSE+VR+TVN PEAAAAVPAIREQLD+MG+DVPLVGDFHYNGHTLL D+PECAQALSKY Sbjct: 143 AGSELVRITVNNPEAAAAVPAIREQLDKMGIDVPLVGDFHYNGHTLLNDFPECAQALSKY 202 Query: 122 RINPGNVGKGAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENAGRAEPWS 181 RINPGNVGKGAKRDTQ+AQMIE AC+YDKPVRIGVNWGSLDQALLARIMDENA R++PW Sbjct: 203 RINPGNVGKGAKRDTQYAQMIEAACRYDKPVRIGVNWGSLDQALLARIMDENALRSQPWL 262 Query: 182 AQAVMYEALVTSAIENAQRAEELGMSGDKIILSCKVSGVQDLIAVYRELARRCDYPLHLG 241 AQAVMYEALVTSAIENAQRAEELG++ D+IILSCKVSGVQDLIAVYRELARRCDYPLHLG Sbjct: 263 AQAVMYEALVTSAIENAQRAEELGLAADRIILSCKVSGVQDLIAVYRELARRCDYPLHLG 322 Query: 242 LTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVVVGQEILQTMGLRK 301 LTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRT+EV+VGQEILQTMGLRK Sbjct: 323 LTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMGLRK 382 Query: 302 FTPMVIACPGCGRTTSTVFQDLADKIQTFLREQMPVWKGKYPGVEAMNVAVMGCIVNGPG 361 F PMVIACPGCGRTTSTVFQDLADKIQT+LR+QMPVWK YPGVE MNVAVMGCIVNGPG Sbjct: 383 FAPMVIACPGCGRTTSTVFQDLADKIQTYLRDQMPVWKKAYPGVEGMNVAVMGCIVNGPG 442 Query: 362 ESKHANIGISLPGTGESPAAPVFIDGEKKMTLRGERIAEEFQKVVLEYVESHYGQGS 418 ESKHANIGISLPGTGESPAAPVFIDGEKK+TLRGERIAEEFQ VVL+YV+SHYGQ + Sbjct: 443 ESKHANIGISLPGTGESPAAPVFIDGEKKLTLRGERIAEEFQAVVLDYVKSHYGQAA 499 >ref|YP_001353817.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Janthinobacterium sp. Marseille] gb|ABR88560.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Janthinobacterium sp. Marseille] Length = 423 Score = 722 bits (1863), Expect = 0.0, Method: Composition-based stats. Identities = 355/415 (85%), Positives = 388/415 (93%) Query: 2 SSFPIASGPLARRNSRRVVISHGAREILVGGGAPVMVQSMTNTDTADAIGTAIQIKELAR 61 SS PIA+GP+ RR SR V+S+G RE+ +GG APV+VQSMTNTDTAD IGTAIQIKELAR Sbjct: 3 SSNPIATGPVTRRQSRVAVVSYGGREVRIGGDAPVVVQSMTNTDTADIIGTAIQIKELAR 62 Query: 62 AGSEIVRLTVNTPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLTDYPECAQALSKY 121 AGSE+VR+TVNTPEAAAAVP I EQLD+M + VPLVGDFHYNGH LL DYP+CA+AL+KY Sbjct: 63 AGSELVRITVNTPEAAAAVPEICEQLDKMDIVVPLVGDFHYNGHKLLNDYPDCAKALAKY 122 Query: 122 RINPGNVGKGAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENAGRAEPWS 181 RINPGNVGKG KRDTQFAQMIE AC++DKPVRIGVNWGSLDQ LLARIMDENA R+ PWS Sbjct: 123 RINPGNVGKGNKRDTQFAQMIETACRFDKPVRIGVNWGSLDQELLARIMDENAARSTPWS 182 Query: 182 AQAVMYEALVTSAIENAQRAEELGMSGDKIILSCKVSGVQDLIAVYRELARRCDYPLHLG 241 AQAVMYEALVTSAIENA RAEE+G++GD+IILSCKVSGVQDLIAVYRELARRCDYPLHLG Sbjct: 183 AQAVMYEALVTSAIENAMRAEEVGLAGDRIILSCKVSGVQDLIAVYRELARRCDYPLHLG 242 Query: 242 LTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVVVGQEILQTMGLRK 301 LTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEV+VGQEILQTMGLRK Sbjct: 243 LTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVIVGQEILQTMGLRK 302 Query: 302 FTPMVIACPGCGRTTSTVFQDLADKIQTFLREQMPVWKGKYPGVEAMNVAVMGCIVNGPG 361 FTPMVIACPGCGRTTSTVFQ+LAD IQT+LR+QMPVWK +YPGVEAMNVAVMGCIVNGPG Sbjct: 303 FTPMVIACPGCGRTTSTVFQELADGIQTYLRDQMPVWKKEYPGVEAMNVAVMGCIVNGPG 362 Query: 362 ESKHANIGISLPGTGESPAAPVFIDGEKKMTLRGERIAEEFQKVVLEYVESHYGQ 416 ESKHANIGISLPGTGESPAAPVF+DGEK +TLRG+ IAEEF +VL+YV+SHYG+ Sbjct: 363 ESKHANIGISLPGTGESPAAPVFVDGEKTVTLRGDNIAEEFHAIVLDYVKSHYGK 417 >ref|YP_001099566.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Herminiimonas arsenicoxydans] emb|CAL61439.1| 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase) [Herminiimonas arsenicoxydans] Length = 425 Score = 719 bits (1855), Expect = 0.0, Method: Composition-based stats. Identities = 354/415 (85%), Positives = 387/415 (93%) Query: 2 SSFPIASGPLARRNSRRVVISHGAREILVGGGAPVMVQSMTNTDTADAIGTAIQIKELAR 61 SS PIA+GP +RR SR V+S+G RE+ +GG APV+VQSMTNTDTAD IGTAIQIKELAR Sbjct: 3 SSDPIATGPFSRRKSRIAVVSYGGREVRIGGDAPVVVQSMTNTDTADVIGTAIQIKELAR 62 Query: 62 AGSEIVRLTVNTPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLTDYPECAQALSKY 121 AGSE+VR+TVNTPEAAAAVPAI EQLD+M V VPLVGDFHYNGHTLL DYP+CA+AL+KY Sbjct: 63 AGSEMVRITVNTPEAAAAVPAICEQLDKMDVVVPLVGDFHYNGHTLLNDYPDCAKALAKY 122 Query: 122 RINPGNVGKGAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENAGRAEPWS 181 RINPGNVGKG KRDTQFAQMIE AC++DKPVRIGVNWGSLDQ LLARIMDENA RA PW+ Sbjct: 123 RINPGNVGKGNKRDTQFAQMIETACRFDKPVRIGVNWGSLDQELLARIMDENAARAHPWT 182 Query: 182 AQAVMYEALVTSAIENAQRAEELGMSGDKIILSCKVSGVQDLIAVYRELARRCDYPLHLG 241 AQAVMYEALVTSAIENA RAEE+G++GD+IILSCKVSGVQDLIAVYRELARRCDYPLHLG Sbjct: 183 AQAVMYEALVTSAIENAMRAEEVGLAGDRIILSCKVSGVQDLIAVYRELARRCDYPLHLG 242 Query: 242 LTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVVVGQEILQTMGLRK 301 LTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRT+EV+VGQEILQTMGLRK Sbjct: 243 LTEAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMGLRK 302 Query: 302 FTPMVIACPGCGRTTSTVFQDLADKIQTFLREQMPVWKGKYPGVEAMNVAVMGCIVNGPG 361 FTPMVIACPGCGRTTSTVFQ+LAD IQT+LR+QMPVWK +YPGVEAMNVAVMGCIVNGPG Sbjct: 303 FTPMVIACPGCGRTTSTVFQELADGIQTYLRDQMPVWKKQYPGVEAMNVAVMGCIVNGPG 362 Query: 362 ESKHANIGISLPGTGESPAAPVFIDGEKKMTLRGERIAEEFQKVVLEYVESHYGQ 416 ESKHANIGISLPGTGESPAAPVF+DG K +TLRG+ IA EF +VL+YV+S YG+ Sbjct: 363 ESKHANIGISLPGTGESPAAPVFVDGVKTVTLRGDNIAAEFHAIVLDYVKSRYGK 417 >ref|ZP_08275723.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Oxalobacteraceae bacterium IMCC9480] gb|EGF30810.1| 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase [Oxalobacteraceae bacterium IMCC9480] Length = 429 Score = 707 bits (1824), Expect = 0.0, Method: Composition-based stats. Identities = 358/413 (86%), Positives = 385/413 (93%) Query: 4 FPIASGPLARRNSRRVVISHGAREILVGGGAPVMVQSMTNTDTADAIGTAIQIKELARAG 63 PI SGP RR R+V I HG ILVGG APV+VQSMTNTDTADAIGTAIQIKELARAG Sbjct: 12 LPIPSGPALRRIVRQVAIRHGDHVILVGGDAPVVVQSMTNTDTADAIGTAIQIKELARAG 71 Query: 64 SEIVRLTVNTPEAAAAVPAIREQLDRMGVDVPLVGDFHYNGHTLLTDYPECAQALSKYRI 123 SE+VR+TVN EAAAAVPAIREQLDRMGV+VPLVGDFHYNGHTLL DYP+CA+ALSKYRI Sbjct: 72 SELVRITVNNAEAAAAVPAIREQLDRMGVNVPLVGDFHYNGHTLLNDYPDCARALSKYRI 131 Query: 124 NPGNVGKGAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENAGRAEPWSAQ 183 NPGNVG+GAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENA RA PW+AQ Sbjct: 132 NPGNVGQGAKRDTQFAQMIEVACKYDKPVRIGVNWGSLDQALLARIMDENAKRAVPWTAQ 191 Query: 184 AVMYEALVTSAIENAQRAEELGMSGDKIILSCKVSGVQDLIAVYRELARRCDYPLHLGLT 243 AVMYEAL+TSA++NA RAEELG++ DKIILSCKVSGVQDLIAVYRELA RCDYPLHLGLT Sbjct: 192 AVMYEALITSAVDNALRAEELGLARDKIILSCKVSGVQDLIAVYRELANRCDYPLHLGLT 251 Query: 244 EAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTKEVVVGQEILQTMGLRKFT 303 EAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRT+EV+VGQEILQTMGLRKFT Sbjct: 252 EAGMGSKGIVASTAALSVLLQEGIGDTIRISLTPEPGGDRTREVIVGQEILQTMGLRKFT 311 Query: 304 PMVIACPGCGRTTSTVFQDLADKIQTFLREQMPVWKGKYPGVEAMNVAVMGCIVNGPGES 363 PMVIACPGCGRTTST FQ LAD IQT+LR+QMPVWK YPGVEAMNVAVMGCIVNGPGES Sbjct: 312 PMVIACPGCGRTTSTTFQSLADSIQTYLRDQMPVWKIDYPGVEAMNVAVMGCIVNGPGES 371 Query: 364 KHANIGISLPGTGESPAAPVFIDGEKKMTLRGERIAEEFQKVVLEYVESHYGQ 416 +HANIGISLPGTGE+PAAPVF+DGEK +TLRGE I+EEFQ +VL+YV+SHYG+ Sbjct: 372 RHANIGISLPGTGETPAAPVFVDGEKTVTLRGEHISEEFQAIVLDYVQSHYGK 424