BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3415.p (299 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003776321.1| porphobilinogen deaminase [Herbaspirillum se... 453 e-125 ref|YP_001099316.1| porphobilinogen deaminase [Herminiimonas ars... 366 2e-99 ref|YP_001352832.1| hydroxymethylbilane synthase [Janthinobacter... 365 7e-99 ref|YP_004752065.1| porphobilinogen deaminase [Collimonas fungiv... 359 3e-97 ref|ZP_08273542.1| Porphobilinogen deaminase [Oxalobacteraceae b... 327 2e-87 >ref|YP_003776321.1| porphobilinogen deaminase [Herbaspirillum seropedicae SmR1] gb|ADJ64413.1| porphobilinogen deaminase protein [Herbaspirillum seropedicae SmR1] Length = 318 Score = 453 bits (1165), Expect = e-125, Method: Composition-based stats. Identities = 278/299 (92%), Positives = 284/299 (94%) Query: 1 MWQAEYVRDRLAALYPQCSINILGTTTRGDQILDRALSKVGGKGLFVKELEVAMAEGRAD 60 MWQAEYVRDRLAALYPQCSI+ILGTTTRGDQILDRALSKVGGKGLFVKELEVAMAEGRAD Sbjct: 20 MWQAEYVRDRLAALYPQCSISILGTTTRGDQILDRALSKVGGKGLFVKELEVAMAEGRAD 79 Query: 61 FAVHSLKDVPMELPGGFVLGAILEREDPRDAFVSNDYAGLDELPAGAVVGTSSLRRQAMI 120 AVH LKD+PM+LP GF L AILEREDPRDAFVSNDYA LDELP GAVVGTSSLRRQAMI Sbjct: 80 LAVHCLKDMPMDLPEGFELAAILEREDPRDAFVSNDYAALDELPDGAVVGTSSLRRQAMI 139 Query: 121 AARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRLGLKARIRSFLDPEQSLPSP 180 AARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRLGLKARIRSFLDP QSLPSP Sbjct: 140 AARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRLGLKARIRSFLDPAQSLPSP 199 Query: 181 GQGTLAIEIPEGRDDIKRLLAPLHDGPAAVVSAAERSVSRIFGASCQIPLAAYATLDGER 240 GQGTLAIEIPEGR+DIKRLLAPLHD PAAVVSAAERSVSRIFGASCQIPLAAYATLDG+R Sbjct: 200 GQGTLAIEIPEGREDIKRLLAPLHDEPAAVVSAAERSVSRIFGASCQIPLAAYATLDGQR 259 Query: 241 LHLRAMIATPDGAQAAAAEAEGSPDAPEALGAQVAELLKSRGADAILAACKAQADAASA 299 LHLRAMIATPDG AAAAEAEG APEALGAQVAELLK+RGAD ILAACKAQADAASA Sbjct: 260 LHLRAMIATPDGLHAAAAEAEGPAAAPEALGAQVAELLKARGADDILAACKAQADAASA 318 >ref|YP_001099316.1| porphobilinogen deaminase [Herminiimonas arsenicoxydans] emb|CAL61189.1| Porphobilinogen deaminase (PBG) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) [Herminiimonas arsenicoxydans] Length = 317 Score = 366 bits (939), Expect = 2e-99, Method: Composition-based stats. Identities = 209/299 (69%), Positives = 244/299 (81%), Gaps = 1/299 (0%) Query: 1 MWQAEYVRDRLAALYPQCSINILGTTTRGDQILDRALSKVGGKGLFVKELEVAMAEGRAD 60 MWQAE+VR++LA LYPQC+I ILG TTRGDQILDR LSKVGGKGLFVKELEVA+AE RAD Sbjct: 20 MWQAEHVREKLALLYPQCAIEILGMTTRGDQILDRTLSKVGGKGLFVKELEVAIAERRAD 79 Query: 61 FAVHSLKDVPMELPGGFVLGAILEREDPRDAFVSNDYAGLDELPAGAVVGTSSLRRQAMI 120 AVHSLKDVPM LP GF L A+LEREDPRDAFVSNDYA LD+LP GA+VGTSSLRRQA+I Sbjct: 80 LAVHSLKDVPMSLPEGFALAAVLEREDPRDAFVSNDYASLDDLPDGAIVGTSSLRRQALI 139 Query: 121 AARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRLGLKARIRSFLDPEQSLPSP 180 AARYP+LV++PLRGNLDTRL KLD+G+YAAIILA AGL RLG+ RIR+ LDPEQSLP+P Sbjct: 140 AARYPKLVIRPLRGNLDTRLGKLDKGEYAAIILAAAGLKRLGMPQRIRAVLDPEQSLPAP 199 Query: 181 GQGTLAIEIPEGRDDIKRLLAPLHDGPAAVVSAAERSVSRIFGASCQIPLAAYATLDGER 240 GQG + IEI R D++ LAPL+ A AER+VSR FG SCQIPLAA+AT++ Sbjct: 200 GQGAMGIEIHADRADLQEWLAPLNHEATAQAVTAERTVSRNFGGSCQIPLAAFATIENGT 259 Query: 241 LHLRAMIATPDGAQAAAAEAEGSPDAPEALGAQVAELLKSRGADAILAACKAQADAASA 299 + LRAMIATPDG + A A+ G+ APEALG Q+AELL + A+AIL +CK + DA +A Sbjct: 260 MRLRAMIATPDGKRVARADLNGAAHAPEALGGQIAELLHQQEANAILESCKTE-DAGNA 317 >ref|YP_001352832.1| hydroxymethylbilane synthase [Janthinobacterium sp. Marseille] gb|ABR88938.1| hydroxymethylbilane synthase [Janthinobacterium sp. Marseille] Length = 317 Score = 365 bits (936), Expect = 7e-99, Method: Composition-based stats. Identities = 209/296 (70%), Positives = 243/296 (82%) Query: 1 MWQAEYVRDRLAALYPQCSINILGTTTRGDQILDRALSKVGGKGLFVKELEVAMAEGRAD 60 MWQAE+VR++LA LYPQCSI ILG TTRGDQILDR LSKVGGKGLFVKELEVA+AE RAD Sbjct: 20 MWQAEHVREKLAILYPQCSIEILGMTTRGDQILDRTLSKVGGKGLFVKELEVAIAEQRAD 79 Query: 61 FAVHSLKDVPMELPGGFVLGAILEREDPRDAFVSNDYAGLDELPAGAVVGTSSLRRQAMI 120 AVHSLKDV M LP GF L A+LEREDPRDAFVSN++ L+ LPAGA+VGTSSLRRQA+I Sbjct: 80 LAVHSLKDVAMTLPDGFELAAVLEREDPRDAFVSNEFDTLEALPAGAIVGTSSLRRQALI 139 Query: 121 AARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRLGLKARIRSFLDPEQSLPSP 180 AARYPQLV++PLRGNLD RL KLD G+YAAIILA AGL RLGL ARIRS+L PEQSLP+P Sbjct: 140 AARYPQLVIRPLRGNLDRRLGKLDNGEYAAIILAAAGLKRLGLTARIRSYLPPEQSLPAP 199 Query: 181 GQGTLAIEIPEGRDDIKRLLAPLHDGPAAVVSAAERSVSRIFGASCQIPLAAYATLDGER 240 GQG +AIEI R D+K LAPL+ A+ AER+VSR FG SCQIPLAA+AT+DG Sbjct: 200 GQGAMAIEILSERADLKEWLAPLNHTETALAVTAERTVSRNFGGSCQIPLAAFATIDGVN 259 Query: 241 LHLRAMIATPDGAQAAAAEAEGSPDAPEALGAQVAELLKSRGADAILAACKAQADA 296 + LRA+IATPDG++ A+A+ G+ +APEALG Q+A+ L+ + A AILA CK AD Sbjct: 260 MRLRAIIATPDGSKMASADLSGAANAPEALGRQIADALQQQDAAAILALCKTDADG 315 >ref|YP_004752065.1| porphobilinogen deaminase [Collimonas fungivorans Ter331] gb|AEK61242.1| Porphobilinogen deaminase [Collimonas fungivorans Ter331] Length = 313 Score = 359 bits (921), Expect = 3e-97, Method: Composition-based stats. Identities = 207/291 (71%), Positives = 245/291 (84%) Query: 1 MWQAEYVRDRLAALYPQCSINILGTTTRGDQILDRALSKVGGKGLFVKELEVAMAEGRAD 60 MWQAE+VR+RL+ALYP C+I ILG TTRGDQILDR LSKVGGKGLFVKELEVAMAEGRAD Sbjct: 21 MWQAEHVRERLSALYPDCNIEILGMTTRGDQILDRTLSKVGGKGLFVKELEVAMAEGRAD 80 Query: 61 FAVHSLKDVPMELPGGFVLGAILEREDPRDAFVSNDYAGLDELPAGAVVGTSSLRRQAMI 120 AVHSLKD+PMELP GFVL A+LEREDPRDAFVSNDYA L++LPAGA+VGTSSLRRQA+I Sbjct: 81 LAVHSLKDMPMELPPGFVLSAVLEREDPRDAFVSNDYASLEQLPAGAIVGTSSLRRQALI 140 Query: 121 AARYPQLVVKPLRGNLDTRLAKLDRGDYAAIILAVAGLNRLGLKARIRSFLDPEQSLPSP 180 AAR+P L +KPLRGNL TRLAKLDRG+YAAIILA AGL RLGL RI + ++PEQSLP+P Sbjct: 141 AARFPLLQIKPLRGNLGTRLAKLDRGEYAAIILAAAGLKRLGLADRITAPIEPEQSLPAP 200 Query: 181 GQGTLAIEIPEGRDDIKRLLAPLHDGPAAVVSAAERSVSRIFGASCQIPLAAYATLDGER 240 GQG +AIEI R D++ +LAPL+ P + AER++SR FG SCQ+PLAA+AT+DG++ Sbjct: 201 GQGAMAIEIRADRADLQEILAPLNHLPTELAVTAERTLSRAFGGSCQVPLAAFATIDGDQ 260 Query: 241 LHLRAMIATPDGAQAAAAEAEGSPDAPEALGAQVAELLKSRGADAILAACK 291 + LRAMIATPDG + A A+A G+ DAPE LG +A L+++ A AILA CK Sbjct: 261 MRLRAMIATPDGLRVAVADASGAADAPEVLGETIAAALEAQDAGAILALCK 311 >ref|ZP_08273542.1| Porphobilinogen deaminase [Oxalobacteraceae bacterium IMCC9480] gb|EGF32978.1| Porphobilinogen deaminase [Oxalobacteraceae bacterium IMCC9480] Length = 280 Score = 327 bits (837), Expect = 2e-87, Method: Composition-based stats. Identities = 194/269 (72%), Positives = 223/269 (82%) Query: 26 TTRGDQILDRALSKVGGKGLFVKELEVAMAEGRADFAVHSLKDVPMELPGGFVLGAILER 85 TTRGDQILDR LSKVGGKGLFVKELEVA+AEGRAD AVHSLKDVPMELP GF+L A LER Sbjct: 2 TTRGDQILDRTLSKVGGKGLFVKELEVAIAEGRADLAVHSLKDVPMELPDGFMLAAFLER 61 Query: 86 EDPRDAFVSNDYAGLDELPAGAVVGTSSLRRQAMIAARYPQLVVKPLRGNLDTRLAKLDR 145 EDPRDAFVSN+YA L+ LPAGAVVGTSSLRRQA+IAAR+P LV++PLRGNLDTRL KLDR Sbjct: 62 EDPRDAFVSNEYASLEALPAGAVVGTSSLRRQALIAARFPHLVIRPLRGNLDTRLGKLDR 121 Query: 146 GDYAAIILAVAGLNRLGLKARIRSFLDPEQSLPSPGQGTLAIEIPEGRDDIKRLLAPLHD 205 G+YAAIILA AGL RLG+ RIR L+PE SLP+PGQG +AIEI GR D+ LLAPL Sbjct: 122 GEYAAIILAAAGLKRLGVPERIRMALEPEHSLPAPGQGAMAIEIKAGRTDLAALLAPLDH 181 Query: 206 GPAAVVSAAERSVSRIFGASCQIPLAAYATLDGERLHLRAMIATPDGAQAAAAEAEGSPD 265 A AER++SR FG SCQIPLAA+A +DG++LHLRAM+ATPDG + A+AEA G D Sbjct: 182 LATARAVQAERTLSRAFGGSCQIPLAAFAVVDGDQLHLRAMVATPDGVRVASAEARGPAD 241 Query: 266 APEALGAQVAELLKSRGADAILAACKAQA 294 PEA+G QVA+ L+ + A+ ILA CKA+A Sbjct: 242 NPEAVGQQVADALRGQDAEIILAICKAEA 270