BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3236.p (1046 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_001633191.1| AcrB/AcrD/AcrF family protein [Bordetella pe... 1638 0.0 ref|ZP_03399921.1| Heavy metal efflux pump CzcA [Pseudomonas syr... 1631 0.0 ref|YP_315091.1| heavy metal efflux pump CzcA [Thiobacillus deni... 1604 0.0 ref|YP_348128.1| heavy metal efflux pump CzcA [Pseudomonas fluor... 1599 0.0 ref|YP_001349369.1| CzcA family heavy metal efflux protein [Pseu... 1584 0.0 >ref|YP_001633191.1| AcrB/AcrD/AcrF family protein [Bordetella petrii DSM 12804] emb|CAP44924.1| AcrB/AcrD/AcrF family protein [Bordetella petrii] Length = 1055 Score = 1638 bits (4241), Expect = 0.0, Method: Composition-based stats. Identities = 817/1039 (78%), Positives = 934/1039 (89%) Query: 1 MIEKLIKWSLRSRFLVLFGVLFLGGWGLWALKTTPVDALPDLSDVQVIIRTTYAGQAPQI 60 MIEKLI+WS+ +RFLVL LFL WGLWA+K P+DALPDLSDVQVI+RTTY GQAPQI Sbjct: 1 MIEKLIRWSINNRFLVLLATLFLFFWGLWAIKNAPIDALPDLSDVQVIVRTTYPGQAPQI 60 Query: 61 VENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTDMYWARSRVLEYLNQVQGR 120 VENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVY++FEDGTD+YWARSRVLEYLNQVQGR Sbjct: 61 VENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVYIIFEDGTDLYWARSRVLEYLNQVQGR 120 Query: 121 LPPSAKASLGPDATGVGWIYEYALVDRTGQHDLAQLRSLQDWFLKYELKSLPNVAEVATV 180 LP +AK SLGPDATGVGWIYEYALVDR+G HDL+QLR LQDWFLKYELKS+P+VAEVA++ Sbjct: 121 LPATAKPSLGPDATGVGWIYEYALVDRSGNHDLSQLRGLQDWFLKYELKSVPDVAEVASI 180 Query: 181 GGMVKQYQVVLDPVKLAAYNIAQDKVVDAIKKANQETGGSVLEMAETEYMVRASGYLKTL 240 GGMVKQYQ+V+DP+KLAA+ + QD+V+ A++ +NQE GGSVLE+AE EYMVRASGYL +L Sbjct: 181 GGMVKQYQIVIDPIKLAAFGVTQDQVIQAVRASNQEVGGSVLELAEAEYMVRASGYLASL 240 Query: 241 ADFRNIPLATGRNGVPVKLGDVAIIQFGPEMRRGIAELNGEGESVGGVIILRSGKNARET 300 DFRNIPLA G P+ LGDVA IQ GPE+RRGIAELNGEGE+ GGV+ILRSGKNAR+ Sbjct: 241 EDFRNIPLAVKSGGTPILLGDVATIQLGPEIRRGIAELNGEGETAGGVVILRSGKNARQA 300 Query: 301 IVAVKSRLEELKKSLPAGVEVVPVYDRSQLIDRAIDNLSHKLLEEFIVVAVVCGLFLWHL 360 I AVK++L+ELK SLP GVE+VP YDRS+LIDRAI+NL+ KL+EEFIVVA+VC +FLWHL Sbjct: 301 ISAVKAKLDELKASLPPGVEIVPTYDRSKLIDRAIENLTSKLIEEFIVVALVCAIFLWHL 360 Query: 361 RSALVAIVSLPLGIMIAFIVMRYQGVNANIMSLGGIAIAIGAMVDAAVVMIENAHKHIEE 420 RSALVAI+SLPLG++ AFI+M YQGV+ANIMSLGGIAIAIGAMVDAAVVMIENAHKH+E Sbjct: 361 RSALVAIISLPLGVLTAFIIMHYQGVSANIMSLGGIAIAIGAMVDAAVVMIENAHKHVET 420 Query: 421 WKHRHPGQPLQGGNHWRVIGEAAAEVGPTLFFCLLIITLSFIPVFTLEAQEGRLFGPLAF 480 W+H H GQ L+G HWRV+ AAAEVGP LFF LLIITLSFIPVFTL+AQEGRLFGPLAF Sbjct: 421 WRHEHLGQELRGEAHWRVMANAAAEVGPALFFSLLIITLSFIPVFTLQAQEGRLFGPLAF 480 Query: 481 TKTYAMAGAAGLSVTLIPILMGYMIRGKIPSENSNPLNRWLIRCYRPLLEAVLRRPRTTL 540 TKTYAMAGAAGL+VTL+P+LMGY IRG+IP E NPLNR+LIR YRPLL+AVLRRPRTTL Sbjct: 481 TKTYAMAGAAGLAVTLVPVLMGYWIRGRIPPEEKNPLNRFLIRIYRPLLDAVLRRPRTTL 540 Query: 541 AIAALALLTTLWPISRLGGEFLPQMDEEDLLYMPSALPGLSASKAAELLQQTDRLIKTVP 600 A A + LLT +WP +RLGGEFLP +DE DLLYMPSALPGLSASKA+ELLQ TDR+I+TVP Sbjct: 541 AAALIILLTAIWPATRLGGEFLPPLDEGDLLYMPSALPGLSASKASELLQLTDRMIRTVP 600 Query: 601 EVASVFGKAGRAESATDPAPLEMFETTIQFKPRDQWRPGMTPTKLVNELDRVVKVPGLSN 660 EVASVFGKAGRAE+ATDPAPLEMFETT+Q KP DQWRPGMT KL+ LD VKVPGL+N Sbjct: 601 EVASVFGKAGRAETATDPAPLEMFETTVQLKPHDQWRPGMTVDKLIQALDDAVKVPGLAN 660 Query: 661 IWVPPIRNRLDMLATGIKSPIGVKVSGTSLADIDKTAQQIEQVAKEVPGVSSALAERLSG 720 IWVPPIRNRLDMLATGIKSPIGVKV+ +LADI+ A IEQVAK VPGVSSALAERL+G Sbjct: 661 IWVPPIRNRLDMLATGIKSPIGVKVAAANLADIESVALAIEQVAKTVPGVSSALAERLTG 720 Query: 721 GRYVDVDIDRLTAANYGLNIADVQSIVSSAIGGENVGETIEGLARYPISVRYPRETRDSL 780 GRYVDV +DR++AA YGL+IADVQS+VS+A+GGEN+GET+EGLARYPI+VRYPRE RDS+ Sbjct: 721 GRYVDVQVDRISAARYGLSIADVQSVVSAAVGGENIGETVEGLARYPINVRYPREIRDSV 780 Query: 781 ERLRDLPILTVSGQQITLGTVAKLKISDGPPMLKSENARPSGWIYVDVRGRDLSSVVADL 840 E LR+LP+ T +GQQITLGTVA++ I +GPPMLKSENARP+GW+Y+DVRGRDL+SVV+DL Sbjct: 781 EGLRNLPMFTSNGQQITLGTVARIAIENGPPMLKSENARPTGWVYIDVRGRDLASVVSDL 840 Query: 841 RAAVSSKVKLTPGLSIAYSGQFEYLERANARLKLVVPATLMIIFVLLYLTFRRFDEAALI 900 R AV+ +V L PG+SI++SGQFEY+ERA ARL LV+PATL+IIFVLLYLTFRRFDEA LI Sbjct: 841 RHAVAQQVALKPGMSISFSGQFEYMERATARLTLVIPATLLIIFVLLYLTFRRFDEALLI 900 Query: 901 MASLPFALVGGIWFLYAQGYNLSVATGVGFIALAGVSAEFGVVMLLYLKQAVSAREQQGG 960 MA+LPFALVGG+WFLY Y+LSV G+GFIALAGVSAEFGVVML YLKQA ++R+ G Sbjct: 901 MATLPFALVGGVWFLYLLNYHLSVPAGIGFIALAGVSAEFGVVMLFYLKQAAASRQDSGL 960 Query: 961 TISVPVLEDAIREGAVLRVRPKAMTVAVILAGLIPILWGSGAGSEVMSRIAAPMVGGMIT 1020 +++ VLEDAIREGAV+RVRPKAMTVAVILAGL+PIL GSGAGSE+MSRIAAPMVGGMIT Sbjct: 961 SLTPSVLEDAIREGAVMRVRPKAMTVAVILAGLLPILLGSGAGSEIMSRIAAPMVGGMIT 1020 Query: 1021 APLLSMFVIPAAYRLMRGR 1039 APLLSMFVIPAAYRLMRGR Sbjct: 1021 APLLSMFVIPAAYRLMRGR 1039 >ref|ZP_03399921.1| Heavy metal efflux pump CzcA [Pseudomonas syringae pv. tomato T1] ref|ZP_07230935.1| heavy metal efflux pump CzcA [Pseudomonas syringae pv. tomato Max13] ref|ZP_07250585.1| heavy metal efflux pump CzcA [Pseudomonas syringae pv. tomato K40] gb|EEB57025.1| Heavy metal efflux pump CzcA [Pseudomonas syringae pv. tomato T1] Length = 1052 Score = 1631 bits (4224), Expect = 0.0, Method: Composition-based stats. Identities = 826/1045 (79%), Positives = 929/1045 (88%), Gaps = 1/1045 (0%) Query: 1 MIEKLIKWSLRSRFLVLFGVLFLGGWGLWALKTTPVDALPDLSDVQVIIRTTYAGQAPQI 60 MI LI+WS+ +RFLVL LF+ WG+W++++TP+DALPDLSDVQVIIRT YAGQAPQI Sbjct: 1 MIAALIRWSVANRFLVLLATLFVTAWGIWSVQSTPIDALPDLSDVQVIIRTPYAGQAPQI 60 Query: 61 VENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTDMYWARSRVLEYLNQVQGR 120 VENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTD+YWARSRVLEYL+Q+Q R Sbjct: 61 VENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTDLYWARSRVLEYLSQIQSR 120 Query: 121 LPPSAKASLGPDATGVGWIYEYALVDRTGQHDLAQLRSLQDWFLKYELKSLPNVAEVATV 180 LP SAK +LGPDATGVGWIY+YALVDR+G HDLAQLR+LQDWFLK+ELK+LPNVAEVATV Sbjct: 121 LPASAKPALGPDATGVGWIYQYALVDRSGGHDLAQLRALQDWFLKFELKTLPNVAEVATV 180 Query: 181 GGMVKQYQVVLDPVKLAAYNIAQDKVVDAIKKANQETGGSVLEMAETEYMVRASGYLKTL 240 GGMVKQYQV LDP+KLA+ I Q +V AI KANQETGG+VLEMAETE++VRASGYLKTL Sbjct: 181 GGMVKQYQVQLDPLKLASLGITQYEVTAAIGKANQETGGAVLEMAETEFIVRASGYLKTL 240 Query: 241 ADFRNIPLATGRNGVPVKLGDVAIIQFGPEMRRGIAELNGEGESVGGVIILRSGKNARET 300 DFR IPL G GVPV LGDVA IQ GPEMRRGI EL+GEGE+VGGV+ILRSGKNARET Sbjct: 241 NDFRAIPLKLGSGGVPVTLGDVATIQLGPEMRRGITELDGEGETVGGVVILRSGKNARET 300 Query: 301 IVAVKSRLEELKKSLPAGVEVVPVYDRSQLIDRAIDNLSHKLLEEFIVVAVVCGLFLWHL 360 I AVK++L+ELKKSLP+GVE+V YDRS+LIDRA++NLSHKL+EEFIVVA+VCG+FLWHL Sbjct: 301 IAAVKTKLDELKKSLPSGVEIVTTYDRSKLIDRAVENLSHKLIEEFIVVALVCGIFLWHL 360 Query: 361 RSALVAIVSLPLGIMIAFIVMRYQGVNANIMSLGGIAIAIGAMVDAAVVMIENAHKHIEE 420 RS+LVAI+SLP+G++IAFIVMRYQG+NANIMSLGGIAIAIGAMVDAAVVMIENAHK +E Sbjct: 361 RSSLVAIISLPVGVLIAFIVMRYQGINANIMSLGGIAIAIGAMVDAAVVMIENAHKKVEA 420 Query: 421 WKHRHPGQPLQGGNHWRVIGEAAAEVGPTLFFCLLIITLSFIPVFTLEAQEGRLFGPLAF 480 W +PG+ L G HW V+ EAAAEVGP LFFCLLIITLSFIPVFTLEAQEGRLFGPLAF Sbjct: 421 WHVANPGEELNGERHWHVMTEAAAEVGPALFFCLLIITLSFIPVFTLEAQEGRLFGPLAF 480 Query: 481 TKTYAMAGAAGLSVTLIPILMGYMIRGKIPSENSNPLNRWLIRCYRPLLEAVLRRPRTTL 540 TKTYAMA AAGLSVTL+P+LMGY IRG+IPSE NPLNRWLIR Y+P L+AVLRRP+ TL Sbjct: 481 TKTYAMAAAAGLSVTLVPVLMGYWIRGRIPSEQQNPLNRWLIRIYQPALDAVLRRPKITL 540 Query: 541 AIAALALLTTLWPISRLGGEFLPQMDEEDLLYMPSALPGLSASKAAELLQQTDRLIKTVP 600 +A ++ LWP+SRLGGEFLP +DE DLLYMPSALPGLSA KAA+LLQQTDRLIKTVP Sbjct: 541 LVALFVFVSALWPMSRLGGEFLPPLDEGDLLYMPSALPGLSAQKAAQLLQQTDRLIKTVP 600 Query: 601 EVASVFGKAGRAESATDPAPLEMFETTIQFKPRDQWRPGMTPTKLVNELDRVVKVPGLSN 660 EV VFGKAGRAE+ATDPAPLEMFETTIQFKP +QWRPGMT KLV ELDRVV+VPGL+N Sbjct: 601 EVEHVFGKAGRAETATDPAPLEMFETTIQFKPHEQWRPGMTQEKLVEELDRVVRVPGLTN 660 Query: 661 IWVPPIRNRLDMLATGIKSPIGVKVSGTSLADIDKTAQQIEQVAKEVPGVSSALAERLSG 720 IW+PPIRNR+DMLATGIKSPIGVKV+GT+L +ID Q +E+VAK+VPGVSSALAERL+G Sbjct: 661 IWIPPIRNRIDMLATGIKSPIGVKVAGTNLTEIDAATQAVERVAKDVPGVSSALAERLTG 720 Query: 721 GRYVDVDIDRLTAANYGLNIADVQSIVSSAIGGENVGETIEGLARYPISVRYPRETRDSL 780 GRY+DVDIDR AA YGLNIADVQSIV+ AIGGENVGETIEGLAR+PI+VRYPRE RDSL Sbjct: 721 GRYIDVDIDRKAAARYGLNIADVQSIVAGAIGGENVGETIEGLARFPINVRYPREWRDSL 780 Query: 781 ERLRDLPILTVSGQQITLGTVAKLKISDGPPMLKSENARPSGWIYVDVRGRDLSSVVADL 840 L LPI T G QITLGTVAK+K+SDGPPMLKSENARPSGW+Y+DVRGRD++SVVADL Sbjct: 781 GALEQLPIYTPLGSQITLGTVAKVKVSDGPPMLKSENARPSGWVYIDVRGRDIASVVADL 840 Query: 841 RAAVSSKVKLTPGLSIAYSGQFEYLERANARLKLVVPATLMIIFVLLYLTFRRFDEAALI 900 R V+ +VKL PG+S++YSGQFE+LERANARLKLVVPATL+IIFVLLYLTF RFDEA LI Sbjct: 841 RRVVNEQVKLQPGMSLSYSGQFEFLERANARLKLVVPATLLIIFVLLYLTFARFDEALLI 900 Query: 901 MASLPFALVGGIWFLYAQGYNLSVATGVGFIALAGVSAEFGVVMLLYLKQAVSAREQQGG 960 MA+LPFAL GG WFLY G+NLSVATGVGFIALAGVSAEFGV+MLLYLK A + RE G Sbjct: 901 MATLPFALTGGAWFLYLLGFNLSVATGVGFIALAGVSAEFGVIMLLYLKNAWAEREDLGD 960 Query: 961 TISVPVLEDAIREGAVLRVRPKAMTVAVILAGLIPILWGSGAGSEVMSRIAAPMVGGMIT 1020 + ++ AIREGAV RVRPKAMTVAVI+AGL+PIL GSG GSEVMSRIAAPMVGGM+T Sbjct: 961 STERGLVA-AIREGAVQRVRPKAMTVAVIIAGLLPILLGSGTGSEVMSRIAAPMVGGMVT 1019 Query: 1021 APLLSMFVIPAAYRLMRGRQPKANP 1045 APLLS+FVIPAAYRLMR R + P Sbjct: 1020 APLLSLFVIPAAYRLMRRRHLQDEP 1044 >ref|YP_315091.1| heavy metal efflux pump CzcA [Thiobacillus denitrificans ATCC 25259] gb|AAZ97286.1| heavy metal efflux pump CzcA [Thiobacillus denitrificans ATCC 25259] Length = 1060 Score = 1604 bits (4153), Expect = 0.0, Method: Composition-based stats. Identities = 819/1046 (78%), Positives = 924/1046 (88%), Gaps = 5/1046 (0%) Query: 1 MIEKLIKWSLRSRFLVLFGVLFLGGWGLWALKTTPVDALPDLSDVQVIIRTTYAGQAPQI 60 MI +LI+WS+ +RFLVL LF WG+WA+KTTP+DALPDLSDVQVIIRT Y GQAPQI Sbjct: 1 MIARLIRWSVANRFLVLLATLFTVAWGIWAVKTTPIDALPDLSDVQVIIRTAYPGQAPQI 60 Query: 61 VENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTDMYWARSRVLEYLNQVQGR 120 VENQVTYPLATTMLSVPGAKTVRG+SFFGDSFVYV+FEDGTD+YWARSRVLEYL+QVQ R Sbjct: 61 VENQVTYPLATTMLSVPGAKTVRGFSFFGDSFVYVIFEDGTDLYWARSRVLEYLSQVQAR 120 Query: 121 LPPSAKASLGPDATGVGWIYEYALVDRTGQHDLAQLRSLQDWFLKYELKSLPNVAEVATV 180 LP +A+ +LGPDATGV WIY+YALVDRTG+HDLAQLRSLQDWFLKYELK+LPNVAEVATV Sbjct: 121 LPATARPALGPDATGVSWIYQYALVDRTGKHDLAQLRSLQDWFLKYELKTLPNVAEVATV 180 Query: 181 GGMVKQYQVVLDPVKLAAYNIAQDKVVDAIKKANQETGGSVLEMAETEYMVRASGYLKTL 240 GGMVKQ QV+LDPVKLA + + D+ + AI+ ANQETGG+VLE+AETE MVRASGYL+++ Sbjct: 181 GGMVKQVQVMLDPVKLAGFGVTHDQAIAAIRAANQETGGAVLELAETELMVRASGYLESV 240 Query: 241 ADFRNIPLATGRNGVPVKLGDVAIIQFGPEMRRGIAELNGEGESVGGVIILRSGKNARET 300 ADFR IPL PV LGDVA IQ GPEMRRGI EL+GEGE+VGGV++LRSGKNARET Sbjct: 241 ADFRAIPLKLA-GTTPVSLGDVAHIQLGPEMRRGIGELDGEGEAVGGVVVLRSGKNARET 299 Query: 301 IVAVKSRLEELKKSLPAGVEVVPVYDRSQLIDRAIDNLSHKLLEEFIVVAVVCGLFLWHL 360 I AVK++L+ LK SLPAGVE+VP YDRSQLIDRAIDNLS KL+EEFIVVA+VC LFLWHL Sbjct: 300 IAAVKAKLDTLKVSLPAGVEIVPTYDRSQLIDRAIDNLSDKLVEEFIVVALVCALFLWHL 359 Query: 361 RSALVAIVSLPLGIMIAFIVMRYQGVNANIMSLGGIAIAIGAMVDAAVVMIENAHKHIEE 420 RS+LVAIVSLPLG++IAFIVMR QG+NANIMSLGGIAIAIGAMVDAAVVMIENAHK IE Sbjct: 360 RSSLVAIVSLPLGVLIAFIVMRQQGINANIMSLGGIAIAIGAMVDAAVVMIENAHKKIEA 419 Query: 421 WKHRHPGQPLQGGNHWRVIGEAAAEVGPTLFFCLLIITLSFIPVFTLEAQEGRLFGPLAF 480 W H HPG+ L G HW+V+ +AAAEVGP LFF LLIITLSFIPVFTLEAQEGRLFGPLAF Sbjct: 420 WHHAHPGETLAGETHWKVVTDAAAEVGPALFFSLLIITLSFIPVFTLEAQEGRLFGPLAF 479 Query: 481 TKTYAMAGAAGLSVTLIPILMGYMIRGKIPSENSNPLNRWLIRCYRPLLEAVLRRPRTTL 540 TKTYAMA AAGLSVTLIP+LMGY IRGKIP E NPLNRWLIR Y PLLEAVLRRP TL Sbjct: 480 TKTYAMAAAAGLSVTLIPVLMGYWIRGKIPDETKNPLNRWLIRAYHPLLEAVLRRPGITL 539 Query: 541 AIAALALLTTLWPISRLGGEFLPQMDEEDLLYMPSALPGLSASKAAELLQQTDRLIKTVP 600 A AAL LT LWP+SRLGGEFLP +DE DLLYMPSALPGLSA KA+ELLQQT+R+I++VP Sbjct: 540 AGAALIFLTALWPMSRLGGEFLPPLDEGDLLYMPSALPGLSAQKASELLQQTNRMIRSVP 599 Query: 601 EVASVFGKAGRAESATDPAPLEMFETTIQFKPRDQWRPGMTPTKLVNELDRVVKVPGLSN 660 EVA V+GKAGRAE+ATDPAPLEMFETTIQFKPR+QWR GMTP +LV ELDR V+VPGL+N Sbjct: 600 EVARVYGKAGRAETATDPAPLEMFETTIQFKPREQWRAGMTPDELVEELDRAVRVPGLAN 659 Query: 661 IWVPPIRNRLDMLATGIKSPIGVKVSGTSLADIDKTAQQIEQVAKEVPGVSSALAERLSG 720 IWVPPIRNR+DMLATGIKSP+GVK++G+ LADID+ AQ +E+VAK VPGVSSALAERL+G Sbjct: 660 IWVPPIRNRIDMLATGIKSPVGVKIAGSHLADIDRIAQDVERVAKTVPGVSSALAERLTG 719 Query: 721 GRYVDVDIDRLTAANYGLNIADVQSIVSSAIGGENVGETIEGLARYPISVRYPRETRDSL 780 GRYVDVDIDR AA YG+NI DVQS V++ IGGEN+GET+EGLARYPI+VRYPRE RD+ Sbjct: 720 GRYVDVDIDRAAAARYGMNIGDVQSAVANLIGGENIGETVEGLARYPINVRYPREWRDTP 779 Query: 781 ERLRDLPILTVSGQQITLGTVAKLKISDGPPMLKSENARPSGWIYVDVRGRDLSSVVADL 840 ++L LPIL +G +ITLG VA +++SDGPPMLKSENARPSGW+YVDVRGRDL+S VADL Sbjct: 780 DKLAALPILAPNGSRITLGMVAAVRVSDGPPMLKSENARPSGWVYVDVRGRDLASTVADL 839 Query: 841 RAAVSSKVKLTPGLSIAYSGQFEYLERANARLKLVVPATLMIIFVLLYLTFRRFDEAALI 900 +AAV++ VKL PG+S+AYSGQFE++ERANARLKLVVPATL+IIFVLLYLTF RFDEA LI Sbjct: 840 QAAVAAGVKLEPGMSLAYSGQFEFMERANARLKLVVPATLLIIFVLLYLTFSRFDEAVLI 899 Query: 901 MASLPFALVGGIWFLYAQGYNLSVATGVGFIALAGVSAEFGVVMLLYLKQAVSAREQQGG 960 MA+LPFAL GG+WFLYA Y LSVATGVGFIALAGVSAEFGV+MLLYLK A A+ ++G Sbjct: 900 MATLPFALTGGVWFLYAMDYQLSVATGVGFIALAGVSAEFGVIMLLYLKNAWDAKREEGK 959 Query: 961 TISVPVLE----DAIREGAVLRVRPKAMTVAVILAGLIPILWGSGAGSEVMSRIAAPMVG 1016 T + E +AIREGAV RVRPKAMTVAVI+AGL+PIL GSG GSEVMSRIAAPMVG Sbjct: 960 TGEADLGEADLLEAIREGAVQRVRPKAMTVAVIVAGLLPILLGSGTGSEVMSRIAAPMVG 1019 Query: 1017 GMITAPLLSMFVIPAAYRLMRGRQPK 1042 GMITAPLLSMFVIPAAY LMR +P+ Sbjct: 1020 GMITAPLLSMFVIPAAYYLMRRPRPQ 1045 >ref|YP_348128.1| heavy metal efflux pump CzcA [Pseudomonas fluorescens Pf0-1] gb|ABA74139.1| heavy metal RND efflux transporter, CzcA family [Pseudomonas fluorescens Pf0-1] Length = 1056 Score = 1599 bits (4140), Expect = 0.0, Method: Composition-based stats. Identities = 813/1043 (77%), Positives = 918/1043 (88%), Gaps = 1/1043 (0%) Query: 1 MIEKLIKWSLRSRFLVLFGVLFLGGWGLWALKTTPVDALPDLSDVQVIIRTTYAGQAPQI 60 MI LI+WS+ +RFLVL LF+ GWG+W+++ TP+DALPDLSDVQVIIRT Y GQAPQI Sbjct: 1 MIAALIRWSVANRFLVLLATLFVTGWGVWSVQNTPIDALPDLSDVQVIIRTPYPGQAPQI 60 Query: 61 VENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTDMYWARSRVLEYLNQVQGR 120 VENQVTYPL TTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTD YWARSRVLEYL+Q+Q R Sbjct: 61 VENQVTYPLTTTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTDQYWARSRVLEYLSQIQSR 120 Query: 121 LPPSAKASLGPDATGVGWIYEYALVDRTGQHDLAQLRSLQDWFLKYELKSLPNVAEVATV 180 LP K LGPDATGVGWIY+YALVDR+G HDLAQLR+LQDWFLK+ELK+LP+VAEVATV Sbjct: 121 LPAGVKPGLGPDATGVGWIYQYALVDRSGGHDLAQLRALQDWFLKFELKTLPDVAEVATV 180 Query: 181 GGMVKQYQVVLDPVKLAAYNIAQDKVVDAIKKANQETGGSVLEMAETEYMVRASGYLKTL 240 GGMVKQYQV DPV+LA+ I +V +AI KANQETGG+VLEMAETE++VRASGYLKTL Sbjct: 181 GGMVKQYQVQPDPVRLASLGITLAQVREAIGKANQETGGAVLEMAETEFIVRASGYLKTL 240 Query: 241 ADFRNIPLATGRNGVPVKLGDVAIIQFGPEMRRGIAELNGEGESVGGVIILRSGKNARET 300 DFR IPL G GVPV LGDVA +Q GP+MRRGI EL+G+GE+VGGV+ILRSGKNARET Sbjct: 241 DDFRAIPLKLGAGGVPVTLGDVATVQTGPDMRRGITELDGQGETVGGVVILRSGKNARET 300 Query: 301 IVAVKSRLEELKKSLPAGVEVVPVYDRSQLIDRAIDNLSHKLLEEFIVVAVVCGLFLWHL 360 I AVK++L+++K SLP GVE+V YDRS+LIDRA++NLSHKLLEEFIVVA+VCG+FLWHL Sbjct: 301 IAAVKAKLDDMKSSLPPGVEIVTTYDRSKLIDRAVENLSHKLLEEFIVVALVCGIFLWHL 360 Query: 361 RSALVAIVSLPLGIMIAFIVMRYQGVNANIMSLGGIAIAIGAMVDAAVVMIENAHKHIEE 420 RS+LVAI+SLP+G++IAFIVMRYQG+NANIMSLGGIAIAIGAMVDAAVVMIENAHK IE Sbjct: 361 RSSLVAIISLPVGVLIAFIVMRYQGLNANIMSLGGIAIAIGAMVDAAVVMIENAHKKIEA 420 Query: 421 WKHRHPGQPLQGGNHWRVIGEAAAEVGPTLFFCLLIITLSFIPVFTLEAQEGRLFGPLAF 480 W +PGQ L+G HW+V+ +AAAEVGP LFFCLLIITLSFIPVFTL+AQEGRLFGPLAF Sbjct: 421 WYAANPGQALKGERHWQVMTDAAAEVGPALFFCLLIITLSFIPVFTLQAQEGRLFGPLAF 480 Query: 481 TKTYAMAGAAGLSVTLIPILMGYMIRGKIPSENSNPLNRWLIRCYRPLLEAVLRRPRTTL 540 TKTYAMA AAGLSVTL+P+LMGY IRG+IP E NPLNRWLIR Y+P L+AVLRRP+ TL Sbjct: 481 TKTYAMAAAAGLSVTLVPVLMGYWIRGRIPDERHNPLNRWLIRIYQPALDAVLRRPKFTL 540 Query: 541 AIAALALLTTLWPISRLGGEFLPQMDEEDLLYMPSALPGLSASKAAELLQQTDRLIKTVP 600 +A L ++ WPIS+LGGEFLP +DE DLLYMPSALPGLSA KAA+LLQQTDRLIK+VP Sbjct: 541 LVALLVFVSAAWPISQLGGEFLPPLDEGDLLYMPSALPGLSAQKAAQLLQQTDRLIKSVP 600 Query: 601 EVASVFGKAGRAESATDPAPLEMFETTIQFKPRDQWRPGMTPTKLVNELDRVVKVPGLSN 660 EV VFGKAGRAE+ATDPAPLEMFETTIQFKP DQWRPGMTP KLV ELDRVV+VPGL+N Sbjct: 601 EVEHVFGKAGRAETATDPAPLEMFETTIQFKPHDQWRPGMTPEKLVEELDRVVRVPGLTN 660 Query: 661 IWVPPIRNRLDMLATGIKSPIGVKVSGTSLADIDKTAQQIEQVAKEVPGVSSALAERLSG 720 IW+PPIRNR+DMLATGIKSPIGVKV+G LA ID Q +E+VAK VPGVSSALAERL+G Sbjct: 661 IWIPPIRNRIDMLATGIKSPIGVKVAGNDLAQIDAATQAVERVAKGVPGVSSALAERLTG 720 Query: 721 GRYVDVDIDRLTAANYGLNIADVQSIVSSAIGGENVGETIEGLARYPISVRYPRETRDSL 780 GRY+DVDIDR A YGLNI+DVQSIVS AIGGEN+GETIEGLAR+PI++RYPRE RDS Sbjct: 721 GRYIDVDIDRNAAGRYGLNISDVQSIVSGAIGGENIGETIEGLARFPINIRYPREWRDSP 780 Query: 781 ERLRDLPILTVSGQQITLGTVAKLKISDGPPMLKSENARPSGWIYVDVRGRDLSSVVADL 840 L LPI T SG QITLG +AK+K++DGPPMLKSENARPSGW+Y+DVRGRD++SVVADL Sbjct: 781 GALEQLPIYTPSGSQITLGMLAKIKVTDGPPMLKSENARPSGWVYIDVRGRDIASVVADL 840 Query: 841 RAAVSSKVKLTPGLSIAYSGQFEYLERANARLKLVVPATLMIIFVLLYLTFRRFDEAALI 900 R AV+ +VKL PG+S++YSGQFE+LERANARLKLVVPATL+IIFVLLYLTF RFDEA LI Sbjct: 841 RRAVNEQVKLQPGMSLSYSGQFEFLERANARLKLVVPATLLIIFVLLYLTFARFDEALLI 900 Query: 901 MASLPFALVGGIWFLYAQGYNLSVATGVGFIALAGVSAEFGVVMLLYLKQAVSAREQQGG 960 MA+LPFAL GG WFLY GYNLSVATGVGFIALAGVSAEFGV+MLLYLK A + RE+ G Sbjct: 901 MATLPFALSGGAWFLYLLGYNLSVATGVGFIALAGVSAEFGVIMLLYLKNAWAEREELGD 960 Query: 961 TISVPVLEDAIREGAVLRVRPKAMTVAVILAGLIPILWGSGAGSEVMSRIAAPMVGGMIT 1020 S L AIREGAV RVRPKAMTVAVI+AGL+PIL GSG GSEVMSRIAAPMVGGM+T Sbjct: 961 H-SERGLVAAIREGAVQRVRPKAMTVAVIIAGLLPILLGSGTGSEVMSRIAAPMVGGMVT 1019 Query: 1021 APLLSMFVIPAAYRLMRGRQPKA 1043 APLLS+FVIPAAYRLMR R+ A Sbjct: 1020 APLLSLFVIPAAYRLMRRRRLPA 1042 >ref|YP_001349369.1| CzcA family heavy metal efflux protein [Pseudomonas aeruginosa PA7] gb|ABR80764.1| heavy metal efflux pump, CzcA family [Pseudomonas aeruginosa PA7] Length = 1050 Score = 1584 bits (4102), Expect = 0.0, Method: Composition-based stats. Identities = 807/1041 (77%), Positives = 918/1041 (88%), Gaps = 3/1041 (0%) Query: 1 MIEKLIKWSLRSRFLVLFGVLFLGGWGLWALKTTPVDALPDLSDVQVIIRTTYAGQAPQI 60 MI KLI+WS+ +RFL+L LF+ WG+W+L++TPVDALPD+SDVQVIIRT+Y GQAPQI Sbjct: 1 MIAKLIRWSVANRFLILLATLFIVAWGVWSLRSTPVDALPDISDVQVIIRTSYPGQAPQI 60 Query: 61 VENQVTYPLATTMLSVPGAKTVRGYSFFGDSFVYVLFEDGTDMYWARSRVLEYLNQVQGR 120 VENQVTYPLATTMLSVPGAKTVRG+S FGDSFVYVLFEDGTD+YWARSRVLEYLNQVQ R Sbjct: 61 VENQVTYPLATTMLSVPGAKTVRGFSSFGDSFVYVLFEDGTDLYWARSRVLEYLNQVQSR 120 Query: 121 LPPSAKASLGPDATGVGWIYEYALVDRTGQHDLAQLRSLQDWFLKYELKSLPNVAEVATV 180 LP +AKA+LGPDATGVGWIY+YAL+DR+G+HDLAQLR+LQDWFLKYELK++P+VAEVATV Sbjct: 121 LPSTAKAALGPDATGVGWIYQYALLDRSGRHDLAQLRALQDWFLKYELKTVPDVAEVATV 180 Query: 181 GGMVKQYQVVLDPVKLAAYNIAQDKVVDAIKKANQETGGSVLEMAETEYMVRASGYLKTL 240 GGMVKQYQVVLDPV+LA+ I Q +V++AI KAN+E GG VLE+ E E+MVRASGYL+TL Sbjct: 181 GGMVKQYQVVLDPVRLASLGITQGQVIEAIGKANREAGGGVLELGEAEFMVRASGYLETL 240 Query: 241 ADFRNIPLATGRNGVPVKLGDVAIIQFGPEMRRGIAELNGEGESVGGVIILRSGKNARET 300 ADFR IPL NG PV LGDVA IQ GPE+RRGI EL+GEGE+VGGVI+LRSGKNAR+ Sbjct: 241 ADFRAIPLRLAANGSPVTLGDVASIQLGPEVRRGIGELDGEGEAVGGVIVLRSGKNARQA 300 Query: 301 IVAVKSRLEELKKSLPAGVEVVPVYDRSQLIDRAIDNLSHKLLEEFIVVAVVCGLFLWHL 360 I VK++LE LKKSLP GVE+V YDRSQLIDRA+ NLSHKL+EEFIVVA+VC FLWHL Sbjct: 301 IAHVKAKLETLKKSLPEGVEIVTTYDRSQLIDRAVSNLSHKLIEEFIVVALVCAAFLWHL 360 Query: 361 RSALVAIVSLPLGIMIAFIVMRYQGVNANIMSLGGIAIAIGAMVDAAVVMIENAHKHIEE 420 RS+LVAIVSLP+G++IA IVMR+QG+NANIMSLGGIAIAIGAMVDAAVVMIENAHK +E Sbjct: 361 RSSLVAIVSLPVGVLIALIVMRHQGINANIMSLGGIAIAIGAMVDAAVVMIENAHKRVEA 420 Query: 421 WKHRHPGQPLQGGNHWRVIGEAAAEVGPTLFFCLLIITLSFIPVFTLEAQEGRLFGPLAF 480 W+ +HPG PL G W+V+ EAA EVGP LFF LLIITLSFIPVFTL+AQEGRLFGPLAF Sbjct: 421 WQEKHPGMPLVGEQRWKVMTEAATEVGPALFFSLLIITLSFIPVFTLQAQEGRLFGPLAF 480 Query: 481 TKTYAMAGAAGLSVTLIPILMGYMIRGKIPSENSNPLNRWLIRCYRPLLEAVLRRPRTTL 540 TKTYAMAGAA LSVTL+P+LMGY IRG++PSE NPLNRWLIR Y+P L+AVLRRPRTTL Sbjct: 481 TKTYAMAGAAALSVTLVPVLMGYWIRGRLPSEQRNPLNRWLIRLYQPALDAVLRRPRTTL 540 Query: 541 AIAALALLTTLWPISRLGGEFLPQMDEEDLLYMPSALPGLSASKAAELLQQTDRLIKTVP 600 A AAL L+ LWP++ LGGEFLP +DE DLLYMPSALPGLSA KA+ELLQ TDRLI++VP Sbjct: 541 ATAALVFLSGLWPLAHLGGEFLPPLDEGDLLYMPSALPGLSAQKASELLQSTDRLIRSVP 600 Query: 601 EVASVFGKAGRAESATDPAPLEMFETTIQFKPRDQWRPGMTPTKLVNELDRVVKVPGLSN 660 EVASVFGKAGRAESATDPAPLEMFETTI+FKP +QWRPGMT KLV ELDRVVKVPGL+N Sbjct: 601 EVASVFGKAGRAESATDPAPLEMFETTIRFKPEEQWRPGMTSEKLVEELDRVVKVPGLTN 660 Query: 661 IWVPPIRNRLDMLATGIKSPIGVKVSGTSLADIDKTAQQIEQVAKEVPGVSSALAERLSG 720 IW+PPIRNR+DMLATG+KSPIG+KV+GT LA+ID+ Q +E+VA+ + GVSSALAERL G Sbjct: 661 IWIPPIRNRIDMLATGVKSPIGIKVAGTDLAEIDQATQAVERVARGIAGVSSALAERLVG 720 Query: 721 GRYVDVDIDRLTAANYGLNIADVQSIVSSAIGGENVGETIEGLARYPISVRYPRETRDSL 780 GRY+DVDIDR AA YG+NIADVQ+IVSSAIGGENVGET+EGLARYPI+VRYPRE RDS+ Sbjct: 721 GRYIDVDIDRQAAARYGMNIADVQTIVSSAIGGENVGETVEGLARYPINVRYPREWRDSV 780 Query: 781 ERLRDLPILTVSGQQITLGTVAKLKISDGPPMLKSENARPSGWIYVDVRGRDLSSVVADL 840 E LR LPI T G QITLG+VA+++IS+GPPMLKSENAR SGW+YVDVRGRDL+SVVA+L Sbjct: 781 EALRQLPIYTAQGGQITLGSVARVRISEGPPMLKSENARLSGWVYVDVRGRDLASVVAEL 840 Query: 841 RAAVSSKVKLTPGLSIAYSGQFEYLERANARLKLVVPATLMIIFVLLYLTFRRFDEAALI 900 R AV +V+L PG+S++YSGQFEYLERANARL LVVPATL IIFVLLYLTF RFDEA LI Sbjct: 841 RQAVDREVRLAPGMSLSYSGQFEYLERANARLGLVVPATLAIIFVLLYLTFGRFDEALLI 900 Query: 901 MASLPFALVGGIWFLYAQGYNLSVATGVGFIALAGVSAEFGVVMLLYLKQAVSAREQQGG 960 MA+LP AL GG+W LY G+NLSVATGVGFIALAGV+AEFGV+ML+YLK A S R GG Sbjct: 901 MATLPLALTGGVWLLYLMGFNLSVATGVGFIALAGVAAEFGVIMLVYLKNAWSVRPDGGG 960 Query: 961 TISVPVLEDAIREGAVLRVRPKAMTVAVILAGLIPILWGSGAGSEVMSRIAAPMVGGMIT 1020 L AIREGAV RVRPKAMTVAVI+AGL+PILW G GSEVMSRIAAPMVGGM+T Sbjct: 961 PGE---LLAAIREGAVQRVRPKAMTVAVIVAGLLPILWSGGTGSEVMSRIAAPMVGGMLT 1017 Query: 1021 APLLSMFVIPAAYRLMRGRQP 1041 APLLS+FVIPAAY LMR RQP Sbjct: 1018 APLLSLFVIPAAYWLMRRRQP 1038