BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3221.p (571 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003049171.1| response regulator receiver modulated diguan... 510 e-142 ref|YP_001983020.1| response regulator [Cellvibrio japonicus Ued... 494 e-137 ref|ZP_08648117.1| Sensory box/GGDEF family protein [gamma prote... 399 e-109 ref|YP_868190.1| response regulator receiver modulated diguanyla... 393 e-107 ref|YP_732682.1| response regulator receiver modulated diguanyla... 390 e-106 >ref|YP_003049171.1| response regulator receiver modulated diguanylate cyclase/phosphodiesterase [Methylotenera mobilis JLW8] gb|ACT48644.1| response regulator receiver modulated diguanylate cyclase/phosphodiesterase [Methylotenera mobilis JLW8] Length = 575 Score = 510 bits (1314), Expect = e-142, Method: Composition-based stats. Identities = 255/562 (45%), Positives = 377/562 (67%) Query: 1 MSIAKTIHAARVSSEIAEAATALEGLKALTQREFDAVLLDYRLPDMDCLDALHAINRTAT 60 M++ + + + ++ +I A+TA+ LK + FD VLLDYRLPDM+C++ L + AT Sbjct: 14 MAVVRVLQSPKLIKDIVHASTAVSALKLFEESAFDVVLLDYRLPDMECIEILRKLTNHAT 73 Query: 61 HNVAVIVLTGGPAEEELGCRCIEAGAQDFLLKSEVSAQICRKALLHAKTRQGLKLQLLDA 120 + AV++LTG +E + CI AGAQDFLLK E+S + KAL+HA+ R L QL++ Sbjct: 74 KHAAVVILTGAVDDEVVERNCIAAGAQDFLLKQELSHRHLTKALVHAQARHALNQQLVET 133 Query: 121 HRRLQLLAENDPLTGLANRYCFDNKLATTLERARQEDMRFGILFMDLDNFKLLNDCYGHS 180 + RL+ LAENDP+TGL+NR F+ KL ++RA++ + + G+LF+D+DNFKL+ND GH Sbjct: 134 YARLKYLAENDPMTGLSNRRYFEEKLRGEIKRAQRFESKIGLLFLDVDNFKLINDSLGHD 193 Query: 181 AGNMLLKIVAKRLLGALHPGEMAARLGGDEFAIIAQDISGTQDLIDLSARIMKAMEDPFV 240 G+ +L+ +A RLL + G++A RLGGDEFAI+ DI L L+ RI+ + +P V Sbjct: 194 VGDQILQQIANRLLTLIRQGDIACRLGGDEFAIVVNDIDEETSLGLLAQRILDCLHEPIV 253 Query: 241 FDNIEQIVTCSIGIASYPECARSAADLCRYADLAMYQVKNTHRNGFYFYSEQLQAKVLYR 300 + ++ SIGI++YPECA +A D+ ++ADLAMY VK RNGF+F++++LQ +V+ + Sbjct: 254 LAKTQHFISISIGISTYPECAHTAEDMLKHADLAMYHVKQHGRNGFHFFTQELQERVMNK 313 Query: 301 MGIENALRSKDLAEQLRVFYQPFVDANSLAICGAEVLVRWQHPLLGLLAPDRFISIAEEC 360 + +E L S L QL+ +YQP ++A++ +CGAEVL+RW HP G+L PD F+ EE Sbjct: 314 IVLEEQLHSGVLQSQLQQYYQPVINASNFNVCGAEVLLRWNHPTRGILTPDSFLDAVEEL 373 Query: 361 GMMAIIDGHTRQASLRQLRAWREEGMIDKSFQMAINISASTLRDRSFPDAFRRDLERTDL 420 G ++ ID +R+ + QL W ++DK+F +AIN S L + SF + DL+ L Sbjct: 374 GFLSEIDTTSRRLACNQLAEWHLTKLVDKNFVLAINASEQLLNEESFLTTIKSDLDNAGL 433 Query: 421 DDVRLSVEVTENILVADFTNAAAALTQLREMGVIIALDDFGTGYSSMSYLRQLPISVLKI 480 LS+EVTE +LV++F AA L +L+++G+ +A+DDFGTGYSSM+YL+ LP S LK+ Sbjct: 434 FGSSLSIEVTEGVLVSNFDKTAAILNKLKDIGLTVAIDDFGTGYSSMAYLKWLPASTLKV 493 Query: 481 DKSFMQQVPQSPEDVRLLRSIITLAKSLDLEVIVEGVETLAQMQLCQALGADILQGYYFS 540 D+SF+Q VP+S D R+L++IITLAKSLD+ VIVEGVET+ Q LC+ GAD+ QGY FS Sbjct: 494 DRSFVQNVPESAADCRVLKAIITLAKSLDMSVIVEGVETIEQAYLCREYGADMFQGYLFS 553 Query: 541 KPLIASEFEYSLLAADSNRTIR 562 + L F + + N I+ Sbjct: 554 RALSPENFADFITKHNPNAWIK 575 >ref|YP_001983020.1| response regulator [Cellvibrio japonicus Ueda107] gb|ACE85224.1| response regulator [Cellvibrio japonicus Ueda107] Length = 587 Score = 494 bits (1271), Expect = e-137, Method: Composition-based stats. Identities = 250/551 (45%), Positives = 358/551 (64%) Query: 2 SIAKTIHAARVSSEIAEAATALEGLKALTQREFDAVLLDYRLPDMDCLDALHAINRTATH 61 +I +T + +I +A A +GL + +FDAVLLDYRLPD+D L+ L +N+ H Sbjct: 15 AIIRTFKKSEWDIDITQAICANDGLVEFDRNDFDAVLLDYRLPDIDGLEVLQLLNQHLHH 74 Query: 62 NVAVIVLTGGPAEEELGCRCIEAGAQDFLLKSEVSAQICRKALLHAKTRQGLKLQLLDAH 121 + A+I+LTG A++EL IEAGAQD L KSE++ + +A+ HA+ R L+ QL D+H Sbjct: 75 HAAIIILTGASADDELERSFIEAGAQDVLFKSEITHKHLTRAITHARARHQLERQLYDSH 134 Query: 122 RRLQLLAENDPLTGLANRYCFDNKLATTLERARQEDMRFGILFMDLDNFKLLNDCYGHSA 181 +RL+ LAEND LTGLANRY FD L + RA+++ + +LF+DLDNFKL+ND GH Sbjct: 135 QRLRSLAENDSLTGLANRYYFDESLRAAIARAKRQHDQLALLFLDLDNFKLINDSLGHVV 194 Query: 182 GNMLLKIVAKRLLGALHPGEMAARLGGDEFAIIAQDISGTQDLIDLSARIMKAMEDPFVF 241 G+ +LK VA+RLL + G++ RLGGDEFAI+A + + L+ RI+ + P V Sbjct: 195 GDEVLKEVAQRLLNVVRAGDVVCRLGGDEFAILAHHFDTEESISQLAQRILDDLRSPIVI 254 Query: 242 DNIEQIVTCSIGIASYPECARSAADLCRYADLAMYQVKNTHRNGFYFYSEQLQAKVLYRM 301 N E ++ SIGIA+YP+ SA+DL + AD+AMY+ K RN F F+S +QA++ R+ Sbjct: 255 GNTEHCISTSIGIATYPDAGNSASDLLKAADMAMYRAKQDGRNNFQFFSPAMQAQMQERI 314 Query: 302 GIENALRSKDLAEQLRVFYQPFVDANSLAICGAEVLVRWQHPLLGLLAPDRFISIAEECG 361 E LR+ + +FYQP VDA + ICGAE L+RW HP G+L P FI++AEE G Sbjct: 315 RTEKELRALIPTDHFILFYQPIVDAQTCTICGAEGLIRWDHPERGILPPSEFITLAEEIG 374 Query: 362 MMAIIDGHTRQASLRQLRAWREEGMIDKSFQMAINISASTLRDRSFPDAFRRDLERTDLD 421 ++ ID +R + +QL WR++G++ F M N+ A L D DL +L Sbjct: 375 LIGEIDSRSRLKACQQLAGWRQQGLVADDFVMKFNVCAQLLTDDDLYQGILDDLHTCELP 434 Query: 422 DVRLSVEVTENILVADFTNAAAALTQLREMGVIIALDDFGTGYSSMSYLRQLPISVLKID 481 +S+E+TE+IL+++ A L Q+ + G+ IA+DDFGTGYSS++YL++LP LKID Sbjct: 435 GNCVSLEITESILISNLERTARKLQQMLDYGIDIAVDDFGTGYSSIAYLKELPARTLKID 494 Query: 482 KSFMQQVPQSPEDVRLLRSIITLAKSLDLEVIVEGVETLAQMQLCQALGADILQGYYFSK 541 + F+Q VP++P D R+LR++I AKSLDL V++EGVET Q ++C+ GAD LQGY FSK Sbjct: 495 RKFVQGVPENPADCRILRAMIVFAKSLDLTVVIEGVETREQARICRDYGADYLQGYLFSK 554 Query: 542 PLIASEFEYSL 552 PL +FE+ L Sbjct: 555 PLSPRDFEHFL 565 >ref|ZP_08648117.1| Sensory box/GGDEF family protein [gamma proteobacterium IMCC2047] gb|EGG99458.1| Sensory box/GGDEF family protein [gamma proteobacterium IMCC2047] Length = 572 Score = 399 bits (1024), Expect = e-109, Method: Composition-based stats. Identities = 217/550 (39%), Positives = 338/550 (61%), Gaps = 2/550 (0%) Query: 1 MSIAKTIHAARVSSEIAEAATALEGLKALTQREFDAVLLDYRLPDMDCLDALHAINRTAT 60 MS + + + S ++ EA +A EGL+ +FD +LLDY+LP M L+ L + A Sbjct: 14 MSATRALKKSGGSIDVTEACSAEEGLELSKAHKFDLILLDYQLPSMSGLELLKQLRGGAN 73 Query: 61 HNVAVIVLTGGPAEEELGCRCIEAGAQDFLLKSEVSAQICRKALLHAKTRQGLKLQLLDA 120 +N V++L+ +E L RCIE GAQDF++KSEV+ +A+ H+K R ++ L ++ Sbjct: 74 YNPPVVMLSHSD-DEALALRCIEEGAQDFIIKSEVTGSRLMRAISHSKERYRIEQALRES 132 Query: 121 HRRLQLLAENDPLTGLANRYCFDNKLATTLERARQEDMRFGILFMDLDNFKLLNDCYGHS 180 H +L+LLAE D LTGLANRY F++ L L A++ ++ +DLD FK +ND GH+ Sbjct: 133 HAKLRLLAEVDSLTGLANRYMFESALKDALPLAKRLKRSVAMVMLDLDKFKYVNDTLGHA 192 Query: 181 AGNMLLKIVAKRLLGALHPGEMAARLGGDEFAIIAQDISGTQDLIDLSARIMKAMEDPFV 240 AG++LL VAKRL G + G++ RLGGDEFAI+ D+ + L+ R++ A+E PF Sbjct: 193 AGDVLLSQVAKRLQGPIRDGDLLCRLGGDEFAILIHDLDDVSKVRRLTDRLLSALEAPFK 252 Query: 241 FDNIEQIVTCSIGIASYPECARSAADLCRYADLAMYQVKNTHRNGFYFYSEQLQAKVLYR 300 + E IV+ SIGI++YPECA + L + AD+A+Y+ K RN FYS +L ++ R Sbjct: 253 VEGQELIVSASIGISTYPECASDSIQLMKCADVALYRSKEGGRNQAQFYSRELHEQIQTR 312 Query: 301 MGIENALRSKDLAEQLRVFYQPFVDANSLAICGAEVLVRWQHPLLGLLAPDRFISIAEEC 360 + +E L +L + YQP +DA S + G E L+RWQHP GL++PD+FI IAEE Sbjct: 313 IELERDLHLAIERHELFLHYQPQIDAQSEKVIGVEALIRWQHPEKGLISPDKFIPIAEET 372 Query: 361 GMMAIIDGHTRQASLRQLRAWREEGMIDK-SFQMAINISASTLRDRSFPDAFRRDLERTD 419 G++ I + +++Q ++W+ + +AIN+SA L + + L + Sbjct: 373 GLIVDIGNWVFETAIKQFQSWQLRFQSPNFNLLIAINLSAIQLGQAGLIETIDQLLSTFE 432 Query: 420 LDDVRLSVEVTENILVADFTNAAAALTQLREMGVIIALDDFGTGYSSMSYLRQLPISVLK 479 ++ RL +E+TE+ + + L L + G+++A+DDFGTGYSS+ L++ P VLK Sbjct: 433 VEPRRLELELTESAITDNNHLCIQLLKDLTDKGIVLAIDDFGTGYSSLQQLKKHPFKVLK 492 Query: 480 IDKSFMQQVPQSPEDVRLLRSIITLAKSLDLEVIVEGVETLAQMQLCQALGADILQGYYF 539 ID+SF+Q + ++ +D++LL++I AK+L +E++ EGVET Q CQ L D +QGYYF Sbjct: 493 IDRSFIQTICENKDDLQLLKAIAAFAKTLGMEIVAEGVETEQQKNWCQNLQFDRIQGYYF 552 Query: 540 SKPLIASEFE 549 +KP+ ++FE Sbjct: 553 AKPMSPADFE 562 >ref|YP_868190.1| response regulator receiver modulated diguanylate cyclase/phosphodiesterase [Shewanella sp. ANA-3] gb|ABK46784.1| response regulator receiver modulated diguanylate cyclase/phosphodiesterase [Shewanella sp. ANA-3] Length = 572 Score = 393 bits (1009), Expect = e-107, Method: Composition-based stats. Identities = 218/549 (39%), Positives = 332/549 (60%), Gaps = 2/549 (0%) Query: 2 SIAKTIHAARVSSEIAEAATALEGLKALTQREFDAVLLDYRLPDMDCLDALHAINRTATH 61 +I + + ++++ + EA A +GL +R FD +LLDY LPD + L+ L +N + T Sbjct: 15 AIIRALRQSKLAFNVVEANCAFDGLNLALERHFDGILLDYLLPDANGLEVLIKLN-SMTQ 73 Query: 62 NVAVIVLTGGPAEEELGCRCIEAGAQDFLLKSEVSAQICRKALLHAKTRQGLKLQLLDAH 121 + V+V+ +E+L RCIE GAQDFLLK EV+++I +A+ +AK R + L L ++H Sbjct: 74 DQTVVVMLSRYEDEKLAQRCIELGAQDFLLKDEVNSRILSRAIRYAKQRSSMALALRNSH 133 Query: 122 RRLQLLAENDPLTGLANRYCFDNKLATTLERARQEDMRFGILFMDLDNFKLLNDCYGHSA 181 ++L+ LAE+D LT L NRY F+ L + RA++ + ++ +DLD+FK +ND GH Sbjct: 134 QKLKELAEHDSLTKLVNRYGFELCLNRAIARAKRSNDFLAVILLDLDDFKAINDTLGHQT 193 Query: 182 GNMLLKIVAKRLLGALHPGEMAARLGGDEFAIIAQDISGTQDLIDLSARIMKAMEDPFVF 241 G++LL VA RL L G++ ARLGGDEF ++ D + ++ R++KA E+ F Sbjct: 194 GDILLVKVASRLSSVLRDGDVIARLGGDEFVVLVTDNDYKYFPMIVANRLLKAFEEVFCL 253 Query: 242 DNIEQIVTCSIGIASYPECARSAADLCRYADLAMYQVKNTHRNGFYFYSEQLQAKVLYRM 301 + ++ SIG+A Y E A +++L + AD+AMY+ K RN FYSE L +V YR Sbjct: 254 GENDVMIGASIGVAFYNEAASDSSELMKCADIAMYRAKKMGRNQIQFYSEALDKEVRYRN 313 Query: 302 GIENALRSKDLAEQLRVFYQPFVDANSLAICGAEVLVRWQHPLLGLLAPDRFISIAEECG 361 IE++LR + +V+YQ VD+ + + G E L+RW HP GL+APD+F+SIAEE G Sbjct: 314 HIESSLRMALKQNEFKVYYQAQVDSQTHQVIGMEALIRWLHPQDGLIAPDQFLSIAEEIG 373 Query: 362 MMAIIDGHTRQASLRQLRAWREE-GMIDKSFQMAINISASTLRDRSFPDAFRRDLERTDL 420 +M I + RQ + W + SF +A+N+SAS + + LE T L Sbjct: 374 LMEEIGDWVLIEACRQAQEWLTRLTPVGHSFTIAVNLSASQIGHIDLYEKIVHALEVTGL 433 Query: 421 DDVRLSVEVTENILVADFTNAAAALTQLREMGVIIALDDFGTGYSSMSYLRQLPISVLKI 480 D L +E+TEN L+ + A L ++ ++GV ALDDFGTG+SS+ +++ PISVLKI Sbjct: 434 DAKALELEITENSLIEEPHEHAKVLDRIAQLGVRFALDDFGTGFSSLEHIKLFPISVLKI 493 Query: 481 DKSFMQQVPQSPEDVRLLRSIITLAKSLDLEVIVEGVETLAQMQLCQALGADILQGYYFS 540 DKSF+ + +D RLL +++ A ++ + EG+ET Q + C A ++LQGY FS Sbjct: 494 DKSFIASYDKDDKDTRLLAALLNFAYGFNVTSVAEGIETAEQAEFCTARNCNVLQGYLFS 553 Query: 541 KPLIASEFE 549 +PL ASEFE Sbjct: 554 RPLEASEFE 562 >ref|YP_732682.1| response regulator receiver modulated diguanylate cyclase/phosphodiesterase [Shewanella sp. MR-4] gb|ABI37625.1| response regulator receiver modulated diguanylate cyclase/phosphodiesterase [Shewanella sp. MR-4] Length = 572 Score = 390 bits (1003), Expect = e-106, Method: Composition-based stats. Identities = 214/549 (38%), Positives = 333/549 (60%), Gaps = 2/549 (0%) Query: 2 SIAKTIHAARVSSEIAEAATALEGLKALTQREFDAVLLDYRLPDMDCLDALHAINRTATH 61 +I + + ++++ + EA A +GL +R FD +LLDY LPD + L+ L +N + T Sbjct: 15 AIIRALRQSKLAFNVIEANCAFDGLNLALERHFDGILLDYLLPDANGLEVLIKLN-SMTQ 73 Query: 62 NVAVIVLTGGPAEEELGCRCIEAGAQDFLLKSEVSAQICRKALLHAKTRQGLKLQLLDAH 121 V+++ +E+L RCIE GAQDFLLK EV+++I +++ +AK R + L L ++H Sbjct: 74 EQTVVLMLSRYEDEKLAQRCIELGAQDFLLKDEVNSRILSRSIRYAKQRASMALALRNSH 133 Query: 122 RRLQLLAENDPLTGLANRYCFDNKLATTLERARQEDMRFGILFMDLDNFKLLNDCYGHSA 181 ++L+ LAE+D LT L NRY F+ L + RA++ + ++ +DLD+FK +ND GH Sbjct: 134 QKLKELAEHDSLTKLMNRYGFELCLNRAIARAKRSNDFLAVILLDLDDFKAINDTLGHQT 193 Query: 182 GNMLLKIVAKRLLGALHPGEMAARLGGDEFAIIAQDISGTQDLIDLSARIMKAMEDPFVF 241 G++LL VA RL L G++ ARLGGDEF ++ D + ++ R++KA E+ F Sbjct: 194 GDILLVKVASRLSSVLRDGDVIARLGGDEFVVLVTDNDYKYFPMIVANRLLKAFEEVFGL 253 Query: 242 DNIEQIVTCSIGIASYPECARSAADLCRYADLAMYQVKNTHRNGFYFYSEQLQAKVLYRM 301 + + ++ SIG+A Y E A ++++L + AD+AMY+ K RN FYSE L +V YR Sbjct: 254 GDNDVMIGASIGVAFYNEAASNSSELMKCADIAMYRAKKMGRNQIQFYSEALDREVRYRN 313 Query: 302 GIENALRSKDLAEQLRVFYQPFVDANSLAICGAEVLVRWQHPLLGLLAPDRFISIAEECG 361 IE++LR +L+V+YQ VD+ + I G E L+RW HP GL++PD+F+ IAEE G Sbjct: 314 HIESSLRMAQKQNELKVYYQAQVDSKTHQIIGMEALIRWLHPQDGLISPDQFLPIAEEIG 373 Query: 362 MMAIIDGHTRQASLRQLRAW-REEGMIDKSFQMAINISASTLRDRSFPDAFRRDLERTDL 420 +M I + RQ + W ++ SF MA+N+SAS + + + L T L Sbjct: 374 LMEEIGDWILLEACRQAQQWLKQLAPTGHSFTMAVNLSASQIGHIDLYEKIVKMLAETGL 433 Query: 421 DDVRLSVEVTENILVADFTNAAAALTQLREMGVIIALDDFGTGYSSMSYLRQLPISVLKI 480 L +E+TEN L+ + A L ++ ++GV ALDDFGTG+SS+ +++ PISVLKI Sbjct: 434 SPKALELEITENCLIEEPHEHAKVLDKIAQLGVRFALDDFGTGFSSLEHIKLFPISVLKI 493 Query: 481 DKSFMQQVPQSPEDVRLLRSIITLAKSLDLEVIVEGVETLAQMQLCQALGADILQGYYFS 540 DKSF+ + +D RLL +++ A ++ + EG+ET+ Q + C D+LQGY FS Sbjct: 494 DKSFIASYDKDEKDARLLTALLNFAYGFNVTSVAEGIETVEQAEFCTERHCDVLQGYLFS 553 Query: 541 KPLIASEFE 549 +P+ ASEFE Sbjct: 554 RPIEASEFE 562