BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3217.p (345 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003774439.1| GGDEF domain transmembrane protein [Herbaspi... 501 e-140 ref|YP_003524392.1| diguanylate cyclase [Sideroxydans lithotroph... 229 7e-58 ref|YP_929453.1| GGDEF domain-containing protein [Shewanella ama... 218 2e-54 ref|YP_002951618.1| GGDEF domain protein [Desulfovibrio magnetic... 216 4e-54 ref|YP_857728.1| GGDEF domain-containing protein [Aeromonas hydr... 212 7e-53 >ref|YP_003774439.1| GGDEF domain transmembrane protein [Herbaspirillum seropedicae SmR1] gb|ADJ62531.1| GGDEF domain transmembrane protein [Herbaspirillum seropedicae SmR1] Length = 334 Score = 501 bits (1290), Expect = e-140, Method: Composition-based stats. Identities = 246/331 (74%), Positives = 286/331 (86%) Query: 1 MKRDLQVSHHQSRTDKPAASDFPGLLQAAMDSLDSQIALIDGAGVIHYVNKSWCDFGKEN 60 MKRDL+ H QS+ +K FP LL+A +DSLDSQIALID AGVIHYVNK+WC+FG EN Sbjct: 1 MKRDLEERHRQSQAEKSVGRQFPRLLRATLDSLDSQIALIDRAGVIHYVNKTWCEFGIEN 60 Query: 61 GMPSGYTWIGSNYLAVCRAAGNRGDCDGRQVYAGIKSVLESDAPCFQYEYPCHSPNEQRW 120 G+P+GY+WIG NYL VCR+AG+RGD DGR+VY GI+SV+ES AP FQYEYPCHSPNEQRW Sbjct: 61 GIPAGYSWIGVNYLVVCRSAGDRGDGDGREVYEGIRSVVESGAPFFQYEYPCHSPNEQRW 120 Query: 121 FMMRIAPVLEAENRYIISHNVITGRKLAEQRIERLNEKLSLLAVTDKLTGLANRMKLDEA 180 FMMRIAPVL AE+ ++ISH VITGRKLAEQR+ERLNEKL+LLAVTDKLTGLANRMKLDE Sbjct: 121 FMMRIAPVLGAEDFFVISHVVITGRKLAEQRVERLNEKLALLAVTDKLTGLANRMKLDEV 180 Query: 181 LESEITRAHRYRKKLSLVLLDVDHFKEVNDKFGHSAGDAVLVRIAEILRANVRATDVVGR 240 L++EI RA RY K LSL+LLD+DHFKEVND FGHS GDAVLVRIAEILRANVR++D+ GR Sbjct: 181 LDNEINRADRYGKNLSLILLDIDHFKEVNDNFGHSTGDAVLVRIAEILRANVRSSDLAGR 240 Query: 241 WGGEEFLLILPECDVVAASRMAEKLRLIVERHSFVFVGKRTCSFGVATYQSGQDCTALLC 300 WGGEEFLLILPECD+ A+RMAEKLRL++E ++FV VG+RTCSFGVA YQ+G D T LL Sbjct: 241 WGGEEFLLILPECDMEDAARMAEKLRLLIENYNFVPVGRRTCSFGVAAYQAGHDRTTLLT 300 Query: 301 LADSALYRAKNSGRNRVEIAADIKPYANTSD 331 LAD ALYRAKN+GRNRVEIAA+++ + D Sbjct: 301 LADLALYRAKNTGRNRVEIAANLESAVSHRD 331 >ref|YP_003524392.1| diguanylate cyclase [Sideroxydans lithotrophicus ES-1] gb|ADE12005.1| diguanylate cyclase [Sideroxydans lithotrophicus ES-1] Length = 304 Score = 229 bits (583), Expect = 7e-58, Method: Composition-based stats. Identities = 136/298 (45%), Positives = 185/298 (62%), Gaps = 13/298 (4%) Query: 30 MDSLDSQIALIDGAGVIHYVNKSWCDFGKENGMPSGYTWIGSNYLAVCRAAGNRGDCDGR 89 +DSL+ QIA+ID GVI YVN++W +FG ENG+ S + G+NYLAVC +G+ GD Sbjct: 12 LDSLEEQIAVIDREGVIVYVNRAWTNFGLENGLASASSGTGNNYLAVCNISGSSGDSLAG 71 Query: 90 QVYAGIKSVLESDAPCFQYEYPCHSPNEQRWFMMRIAPVL-EAENRYIISHNVITGRKLA 148 + AGI+ VL F +EYPCHSP E+RWFMMR AP+ +A N ++ISH+ IT RKLA Sbjct: 72 EAAAGIRDVLAGKRVSFHFEYPCHSPAEKRWFMMRAAPLQGDAGNLFVISHHNITQRKLA 131 Query: 149 EQRIERLNEKLSLLAVTDKLTGLANRMKLDEALESEITRAHRYRKKLSLVLLDVDHFKEV 208 E+RIE L++ D LTGLANR ++ L + R+ R R LS V+ D+DHFK+ Sbjct: 132 EERIE-------FLSLHDPLTGLANRRHFNQFLNNAWRRSSRSRSLLSFVMFDLDHFKDY 184 Query: 209 NDKFGHSAGDAVLVRIAEILRANV-RATDVVGRWGGEEFLLILPECDVVAASRMAEKLRL 267 ND+ GH AGD L+++ ++LRA R D+ R+GGEEF L+L + A+++A+ +R Sbjct: 185 NDELGHLAGDECLIKVGQVLRAAAGRPGDLAVRYGGEEFGLLLEGTCLEDAAKIADAIRQ 244 Query: 268 IVERHSFVFVGKR--TCSFGVATY--QSGQDCTALLCLADSALYRAKNSGRNRVEIAA 321 V + R T S GVA+ + Q L+ AD ALYRAK GRNRV A Sbjct: 245 NVHELDMRYRKTRLITVSAGVASVIPEGEQSEIFLIREADKALYRAKQQGRNRVVCAG 302 >ref|YP_929453.1| GGDEF domain-containing protein [Shewanella amazonensis SB2B] gb|ABM01784.1| GGDEF domain protein protein [Shewanella amazonensis SB2B] Length = 312 Score = 218 bits (554), Expect = 2e-54, Method: Composition-based stats. Identities = 124/297 (41%), Positives = 175/297 (58%), Gaps = 17/297 (5%) Query: 26 LQAAMDSLDSQIALIDGAGVIHYVNKSWCDFGKENGMPSGYTWIGSNYLAVCRAAGNRGD 85 LQA ++S++ Q+ +ID G I Y N +W F +ENGM GY W+G+NYL VC A + Sbjct: 19 LQALLNSVEDQVVVIDIQGTIVYTNLAWNKFAEENGMTPGYNWLGTNYLRVCDGAA---E 75 Query: 86 CDGRQVYAGIKSVLESDAPCFQYEYPCHSPNEQRWFMMRIAPVLEAENRYI-ISHNVITG 144 + GI+ V+ F EYPCHSP QRWFMMR+ + E+RY I+H IT Sbjct: 76 SFSKTAAEGIRQVMAGAEAQFYLEYPCHSPTTQRWFMMRVTEIAGLESRYFAIAHVNITE 135 Query: 145 RKLAEQRIERLNEKLSLLAVTDKLTGLANRMKLDEALESEITRAHRYRKKLSLVLLDVDH 204 RKL E ++ +L ++ D LTGLANR + L +E R+ R + L+L+LLD+DH Sbjct: 136 RKLLELKVAKL-------SMHDPLTGLANRRLFNSFLHNEWRRSQREQVPLTLILLDLDH 188 Query: 205 FKEVNDKFGHSAGDAVLVRIAEILRANV-RATDVVGRWGGEEFLLILPECDVVAASRMAE 263 FK ND FGH GD L +++++L + R TD+ R+GG+EF L+L + A +AE Sbjct: 189 FKSCNDHFGHLVGDEHLQQVSQVLLSVCQRPTDLACRFGGDEFALVLGNTNAAAGLGLAE 248 Query: 264 KLRLIVERHSF-VFVGKR-TCSFGVATYQSGQDC---TALLCLADSALYRAKNSGRN 315 K+R +E + + G R T S G+AT + GQ L LADSALY+AK +G+N Sbjct: 249 KVRSTIENLNIKIEDGLRLTSSLGIATLEPGQQMEQENTLCSLADSALYQAKAAGKN 305 >ref|YP_002951618.1| GGDEF domain protein [Desulfovibrio magneticus RS-1] dbj|BAH73732.1| GGDEF domain protein [Desulfovibrio magneticus RS-1] Length = 687 Score = 216 bits (550), Expect = 4e-54, Method: Composition-based stats. Identities = 126/326 (38%), Positives = 172/326 (52%), Gaps = 20/326 (6%) Query: 8 SHHQSRTDKPAASDFPGLLQAAMDSLDSQIALIDGAGVIHYVNKSWCDFGKENGMPSGYT 67 SH RT K LQ+ +DSL + IALID G I VNK+W DF ++NG+ Sbjct: 221 SHESVRTSKL-------FLQSVLDSLTAHIALIDADGGILLVNKAWRDFARQNGLDPELV 273 Query: 68 WIGSNYLAVCRAAGNRGDCDGRQVYAGIKSVLESDAPCFQYEYPCHSPNEQRWFMMRIAP 127 G+NYL C A R + + AGI+ VL + F EYPCH+P+E+RWF+ R+ P Sbjct: 274 SEGTNYLCACDNAACRNEPEADSFAAGIRKVLSGELKQFAMEYPCHAPHERRWFVGRVTP 333 Query: 128 VL-EAENRYIISHNVITGRKLAEQRIERLNEKLSLLAVTDKLTGLANRMKLDEALESEIT 186 + R +++H IT RKL E + N KL L+ TD LTG+ANR + DEA E Sbjct: 334 FPGDGPPRVVVAHEDITVRKLMEIALAESNRKLEALSATDPLTGIANRRRFDEAFAGEYA 393 Query: 187 RAHRYRKKLSLVLLDVDHFKEVNDKFGHSAGDAVLVRIAEILRANV-RATDVVGRWGGEE 245 R R LSLV+LD+D+FK ND +GH+ GDA L +A + + R D+ R+GGEE Sbjct: 394 RHARTGAPLSLVMLDIDYFKNFNDAYGHAQGDACLAAVARAMAGCLQRPGDLAARYGGEE 453 Query: 246 FLLILPECDVVAASRMAEKLRLIVERHSFVFVGKRTCSFGVATYQSG---------QDCT 296 F+ +LP+ +AE +R V + R+ + V T G D Sbjct: 454 FICLLPDTSPRGTRTVAESIREAVA--ALAIPHARSSAAAVVTVSIGALTAACPPDADPG 511 Query: 297 ALLCLADSALYRAKNSGRNRVEIAAD 322 L D+ LY+AK +GRNRVE D Sbjct: 512 DLFRQVDALLYKAKENGRNRVEAGGD 537 >ref|YP_857728.1| GGDEF domain-containing protein [Aeromonas hydrophila subsp. hydrophila ATCC 7966] gb|ABK36956.1| GGDEF domain protein [Aeromonas hydrophila subsp. hydrophila ATCC 7966] Length = 318 Score = 212 bits (540), Expect = 7e-53, Method: Composition-based stats. Identities = 128/307 (41%), Positives = 175/307 (57%), Gaps = 23/307 (7%) Query: 20 SDFPGLLQAAMDSLDSQIALIDGAGVIHYVNKSWCDFGKENGMPSGYTWIGSNYLAVCRA 79 SD L A ++SL+ QI++ID GVIHY N +W F ++NGMP GY W+G NYL VC Sbjct: 13 SDRAQYLSALLNSLEEQISVIDRDGVIHYTNLAWNSFAEQNGMPEGYDWLGVNYLRVC-- 70 Query: 80 AGNRGDCDGRQVYAGIKSVLESDAPCFQYEYPCHSPNEQRWFMMRIA--PVLEAENRYII 137 N + + GI+ VL + F EYPCHSP+ QRWFMMR++ P +E E Y I Sbjct: 71 -DNSVEPLAQMAAEGIRRVLRHEQQHFHLEYPCHSPDTQRWFMMRVSAIPGIEVE-FYTI 128 Query: 138 SHNVITGRKLAEQRIERLNEKLSLLAVTDKLTGLANRMKLDEALESEITRAHRYRKKLSL 197 SH +T RKL E ++ L++ D LTGLANR + L +E R+ R + +S Sbjct: 129 SHINVTERKLQEL-------DMAYLSLHDPLTGLANRRLFNSFLHNEWRRSMREQTPISF 181 Query: 198 VLLDVDHFKEVNDKFGHSAGDAVLVRIAEILRANV-RATDVVGRWGGEEFLLILPECDVV 256 ++LD+D+FK ND FGH GD L ++ ++L RATD+ R+GG+EF LIL Sbjct: 182 IMLDLDNFKLCNDHFGHQVGDGFLQQVGQLLSTFCQRATDLPCRFGGDEFALILGNTGDE 241 Query: 257 AASRMAEKLRLIVERHSFVFVG----KRTCSFGVATYQSGQDCTA---LLCLADSALYRA 309 AASRM E +R+ + + G + + S G+AT Q + LL AD ALY A Sbjct: 242 AASRMGEAIRVGI--GELLIPGADGLRLSASVGIATLLPQQARVSEEELLTAADMALYLA 299 Query: 310 KNSGRNR 316 K G+NR Sbjct: 300 KQGGKNR 306