BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3198.p (453 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|ZP_08868830.1| integral membrane sensor signal transduction ... 368 1e-99 ref|YP_743966.1| two component system histidine kinase [Granulib... 286 5e-75 ref|YP_001233595.1| integral membrane sensor signal transduction... 273 6e-71 ref|ZP_08632163.1| Integral membrane sensor signal transduction ... 271 1e-70 ref|YP_004282773.1| two-component sensor histidine kinase [Acidi... 271 2e-70 >ref|ZP_08868830.1| integral membrane sensor signal transduction histidine kinase [Azospirillum amazonense Y2] gb|EGY01578.1| integral membrane sensor signal transduction histidine kinase [Azospirillum amazonense Y2] Length = 455 Score = 368 bits (944), Expect = 1e-99, Method: Composition-based stats. Identities = 218/447 (48%), Positives = 292/447 (65%), Gaps = 6/447 (1%) Query: 5 FKFSARTVASCYVVFSLLALAAFATPLWYAWQEFVEQDWRHILHADSERLQRVYEEEGVD 64 + SA T+A YV+ L+ L FA PL YAW+ ++ IL D++R V+ + G D Sbjct: 9 LRSSAYTLAFSYVLLGLVTLVLFAAPLGYAWRVTIDDGRTEILQEDAQRFTEVFRQRGPD 68 Query: 65 ALSKRIDSRVGAIPGGSEDIVLLTDQNMQRLAGNLSAWPTEISAAASSGRFVVDINGNNT 124 L ++ R+ ++ +E ++LLTD LAGNL AWP + + +NG Sbjct: 69 GLVAFLNERM-SMQIAAERLLLLTDAAHTVLAGNLPAWPGDFPERQGVYNAPIKLNGRTV 127 Query: 125 RILARHLILNGRFHLLVAHDINRYRLLENMFIGGLAASGSIIILLGIIGGIAIRRSLLAK 184 + H++L G +HL+VA D+ +R LE F L A+ +++LLG++GG IRR++L + Sbjct: 128 QARLVHVVLPGGYHLVVARDMAHFRPLEQRFWYSLLAAMGVLLLLGMLGGFLIRRAVLRR 187 Query: 185 VKDIDQAASAIVRGDFTHRLPHHGGESELASLVKTANLMLDQIEQLMKGVINASNSIAHD 244 + D+ + A+ IV GD + RLP G+ E +L +T N MLDQIEQL+ GV N SN+IAHD Sbjct: 188 IDDLSRTATGIVLGDLSRRLPTTRGQDEFNTLSRTINGMLDQIEQLVHGVRNVSNAIAHD 247 Query: 245 LRTPLAELRSRLEDLA--RQEMNS--EEVEGAIEDVDRVISIFNALLRLVEIDTGARRAG 300 LRTPLAELRSRLE+++ R M EV+GA+ DVDRVI IFNALLRL EIDTGARR+G Sbjct: 248 LRTPLAELRSRLEEVSVTRPSMTETYAEVDGAVADVDRVIGIFNALLRLAEIDTGARRSG 307 Query: 301 FSDMNAAAVVADVCEFYRPLAESTGKIIDHR-PSGPLVLKGDALLLAQAVANLIDNALKF 359 F+++N A V A EFY P AE G + R G + + GD +LLAQAV NLIDNALKF Sbjct: 308 FAEVNVAEVAAGAVEFYLPAAELKGISLTFRGDQGMMTILGDPILLAQAVGNLIDNALKF 367 Query: 360 IPIGGKVTLSCVQLDDGRVLVRVSDNGPGISDAELPKVQQRFYRGDTSRSTPGVGLGLSL 419 P GG +T+ DG+V + VSDNGPGI D E P+V +RFYRGD R TPGVGLGLSL Sbjct: 368 TPEGGAITVEVSSGADGKVEMSVSDNGPGIPDDEKPRVTERFYRGDMGRGTPGVGLGLSL 427 Query: 420 VASVARLHGGSLELSHNHPGLRAVLIL 446 V++VA+LHGG+ +L+ NHPGLRA + L Sbjct: 428 VSAVAKLHGGAFDLADNHPGLRARMRL 454 >ref|YP_743966.1| two component system histidine kinase [Granulibacter bethesdensis CGDNIH1] gb|ABI61043.1| two component system histidine kinase [Granulibacter bethesdensis CGDNIH1] Length = 498 Score = 286 bits (733), Expect = 5e-75, Method: Composition-based stats. Identities = 175/459 (38%), Positives = 261/459 (56%), Gaps = 13/459 (2%) Query: 3 RFFKFSARTVASCYVVFSLLALAAFATP-------LWYAWQEFVEQDWRHILHADSERLQ 55 R F+ + V S V F++L FA LW+ + + + D++ L Sbjct: 24 RAFRRNLSLVPSASVRFAMLYAGLFAISALALAVFLWWTTAGLLNRQTETAILTDAQGLA 83 Query: 56 RVYEEEGVDALSKRIDSRVGAIPGGSEDIVLLTDQNMQRLAGNLSAWPTEISAAASSGRF 115 + + G+ AL + I R+ + I LLTD +R+AGNL+ WP++++ + Sbjct: 84 ERWNDGGLPALVQGIQERLSE-NLDDDAIYLLTDPEQRRIAGNLAHWPSQMNTTNTWFEL 142 Query: 116 VVDINGNNTRILARHLILNGRFHLLVAHDINRYRLLENMFIGGLAASGSIIILLGIIGGI 175 + G + R L FHLLV D+ L ++ G L + +++ L + G + Sbjct: 143 SIQRAGTKSLARIRRFDLPSGFHLLVGRDVQARARLRDLLTGSLVWAMVVVVALSVAGAL 202 Query: 176 AIRRSLLAKVKDIDQAASAIVRGDFTHRLPHHGGESELASLVKTANLMLDQIEQLMKGVI 235 +R + DI A+AI G+ T R+ G E L +T N MLD+I +LM+GV Sbjct: 203 VVRGLFRRSLADISSVAAAIGAGNLTRRVKLSGRGDEFDRLAETVNDMLDRIGRLMEGVK 262 Query: 236 NASNSIAHDLRTPLAELRSRLED-LARQEMNSE---EVEGAIEDVDRVISIFNALLRLVE 291 SN+IAHDLRTP+A +R+RLED L E +++ VE AI D+D V +IF LLR+ E Sbjct: 263 QVSNAIAHDLRTPIARVRARLEDALTHSEEDTQLAAAVERAIADLDGVTAIFQGLLRIAE 322 Query: 292 IDTGARRAGFSDMNAAAVVADVCEFYRPLAESTGKIIDHRPSGPLVLKGDALLLAQAVAN 351 I++GARR+ F+ + ++AD+CE Y PLAE + PL + GD LL QA+AN Sbjct: 323 IESGARRSAFASTDLQPILADLCELYEPLAEEKNLLFVFDCPDPLPIFGDRSLLQQALAN 382 Query: 352 LIDNALKFIPIGGKVTLSCVQLDDGRVLVRVSDNGPGISDAELPKVQQRFYRGDTSRSTP 411 ++DNA+KF+P GG + LS + + + V+DNGPGI +A+ + +RF+RG+T+RSTP Sbjct: 383 MLDNAIKFLPTGGTLHLSGWR-NGADIFALVADNGPGIPEADRNRATERFFRGETARSTP 441 Query: 412 GVGLGLSLVASVARLHGGSLELSHNHPGLRAVLILRTAS 450 G GLGL+LV +VA+LHGG L L N+PGLRAVLIL A+ Sbjct: 442 GSGLGLALVQAVAQLHGGVLRLEDNNPGLRAVLILHAAT 480 >ref|YP_001233595.1| integral membrane sensor signal transduction histidine kinase [Acidiphilium cryptum JF-5] gb|ABQ29676.1| signal transduction histidine kinase [Acidiphilium cryptum JF-5] Length = 488 Score = 273 bits (697), Expect = 6e-71, Method: Composition-based stats. Identities = 173/454 (38%), Positives = 255/454 (56%), Gaps = 16/454 (3%) Query: 2 NRFFKFSARTVASCYVVFSLLALAAFATPLWYAWQEFVEQDWRHILHADSERLQRVYEEE 61 NR + + A Y + ++ A L+Y+ + + + D+ L +E Sbjct: 22 NRLLRSAGVRFAIFYALVFGISAIVLAGSLYYSTIGLLGRQTHEAIRVDARSLAAHFEAG 81 Query: 62 GVDALSKRIDSRVGAIPGGSEDI-----VLLTDQNMQRLAGNLSAWPTEISAAASSGRFV 116 G+ L +DSR+ SEDI LL D R+AGN+S WP I+ A + Sbjct: 82 GLTGLVLTLDSRI------SEDINDHAIYLLVDPLGNRIAGNMSRWPQGINTAHVWYQVP 135 Query: 117 VDINGNNTRILARHLILNGRFHLLVAHDINRYRLLENMFIGGLAASGSIIILLGIIGGIA 176 ++ G + L R+ L G F LLV D++ L + GL + + + LG++G I Sbjct: 136 LERGGRKSTALMRYYELPGGFQLLVGRDVSTRAQLRRILRDGLLWALAAMAFLGVLGAIV 195 Query: 177 IRRSLLAKVKDIDQAASAIVRGDFTHRLPHHGGESELASLVKTANLMLDQIEQLMKGVIN 236 IR + DI AI RGD T R+ G E L +T N MLD+I +LM GV Sbjct: 196 IRGLFKRSLADISGITRAIARGDLTRRVRRSGNGDEFDELAETINDMLDRIAKLMDGVRE 255 Query: 237 ASNSIAHDLRTPLAELRSRLEDLARQEMNSEEVEGAIE----DVDRVISIFNALLRLVEI 292 SNSIAHDLRTP+ R+RLED A +EE++ A+E D+D ++++F ALLR+ EI Sbjct: 256 VSNSIAHDLRTPITRARARLEDAAAHARTTEELQSAVERATLDLDGIVNVFQALLRIAEI 315 Query: 293 DTGARRAGFSDMNAAAVVADVCEFYRPLAESTGKIIDHRPSGPLVLKGDALLLAQAVANL 352 + GARR+ F D++ A V+ D+ EF+ LAE G +I + + GD +L QAV+NL Sbjct: 316 EAGARRSAFRDVDLAPVLDDLAEFFDALAEERGILIVRDWPKSIPIFGDRDMLQQAVSNL 375 Query: 353 IDNALKFIPIGGKVTLSCVQLDDGRVLVRVSDNGPGISDAELPKVQQRFYRGDTSRSTPG 412 +DNA+KF +V ++ G V ++++D+GPGI +A+L + +RFYR + +RSTPG Sbjct: 376 LDNAIKFSRETDRVVIA-AHAGGGHVEIQIADHGPGIPEADLSRATERFYRAEAARSTPG 434 Query: 413 VGLGLSLVASVARLHGGSLELSHNHPGLRAVLIL 446 GLGL+LV+++A+LHGGSL L +N PGLRA LIL Sbjct: 435 SGLGLALVSAIAQLHGGSLLLENNEPGLRARLIL 468 >ref|ZP_08632163.1| Integral membrane sensor signal transduction histidine kinase [Acidiphilium sp. PM] gb|EGO95985.1| Integral membrane sensor signal transduction histidine kinase [Acidiphilium sp. PM] Length = 464 Score = 271 bits (694), Expect = 1e-70, Method: Composition-based stats. Identities = 172/439 (39%), Positives = 252/439 (57%), Gaps = 17/439 (3%) Query: 17 VVFSLLALAAFATPLWYAWQEFVEQDWRHILHADSERLQRVYEEEGVDALSKRIDSRVGA 76 +VF + A+ A L+Y+ + + + D+ L +E G+ L +DSR+ Sbjct: 14 LVFGISAIV-LAGSLYYSTIGLLGRQTHEAIRVDARSLAAHFEAGGLTGLVLTLDSRI-- 70 Query: 77 IPGGSEDI-----VLLTDQNMQRLAGNLSAWPTEISAAASSGRFVVDINGNNTRILARHL 131 SEDI LL D R+AGN+S WP I+ A + ++ G + L R+ Sbjct: 71 ----SEDINDHAIYLLVDPLGNRIAGNMSRWPQGINTAHVWYQVPLERGGRKSTALMRYY 126 Query: 132 ILNGRFHLLVAHDINRYRLLENMFIGGLAASGSIIILLGIIGGIAIRRSLLAKVKDIDQA 191 L G F LLV D++ L + GL + + + LG++G I IR + DI Sbjct: 127 ELPGGFQLLVGRDVSTRAQLRRILRDGLLWALAAMAFLGVLGAIVIRGLFKRSLADISGI 186 Query: 192 ASAIVRGDFTHRLPHHGGESELASLVKTANLMLDQIEQLMKGVINASNSIAHDLRTPLAE 251 AI RGD T R+ G E L +T N MLD+I +LM GV SNSIAHDLRTP+ Sbjct: 187 TRAIARGDLTRRVRRSGNSDEFDELAETINDMLDRIAKLMDGVREVSNSIAHDLRTPITR 246 Query: 252 LRSRLEDLARQEMNSEEVEGAIE----DVDRVISIFNALLRLVEIDTGARRAGFSDMNAA 307 R+RLED A +EE++ A+E D+D ++++F ALLR+ EI+ GARR+ F D++ A Sbjct: 247 ARARLEDAAAHARTTEELQSAVERATLDLDGIVNVFQALLRIAEIEAGARRSAFRDVDLA 306 Query: 308 AVVADVCEFYRPLAESTGKIIDHRPSGPLVLKGDALLLAQAVANLIDNALKFIPIGGKVT 367 V+ D+ EF+ LAE G +I + + GD +L QAV+NL+DNA+KF +V Sbjct: 307 PVLDDLAEFFDALAEERGILIVRDWPKSIPIFGDRDMLQQAVSNLLDNAIKFSRETDRVV 366 Query: 368 LSCVQLDDGRVLVRVSDNGPGISDAELPKVQQRFYRGDTSRSTPGVGLGLSLVASVARLH 427 ++ G V ++++D+GPGI +A+L + +RFYR + +RSTPG GLGL+LV+++A+LH Sbjct: 367 IA-AHAGGGHVEIQIADHGPGIPEADLSRATERFYRAEAARSTPGSGLGLALVSAIAQLH 425 Query: 428 GGSLELSHNHPGLRAVLIL 446 GGSL L +N PGLRA LIL Sbjct: 426 GGSLLLENNEPGLRARLIL 444 >ref|YP_004282773.1| two-component sensor histidine kinase [Acidiphilium multivorum AIU301] dbj|BAJ79891.1| two-component sensor histidine kinase [Acidiphilium multivorum AIU301] Length = 464 Score = 271 bits (692), Expect = 2e-70, Method: Composition-based stats. Identities = 172/439 (39%), Positives = 252/439 (57%), Gaps = 17/439 (3%) Query: 17 VVFSLLALAAFATPLWYAWQEFVEQDWRHILHADSERLQRVYEEEGVDALSKRIDSRVGA 76 +VF + A+ A L+Y+ + + + D+ L +E G+ L +DSR+ Sbjct: 14 LVFGISAIV-LAGSLYYSTIGLLGRQTHEAIRVDARSLAAHFEAGGLTGLVLTLDSRI-- 70 Query: 77 IPGGSEDI-----VLLTDQNMQRLAGNLSAWPTEISAAASSGRFVVDINGNNTRILARHL 131 SEDI LL D R+AGN+S WP I+ A + ++ G + L R+ Sbjct: 71 ----SEDINDHAIYLLVDPLGNRIAGNMSRWPQGINTAHVWYQVPLERGGRKSTALMRYY 126 Query: 132 ILNGRFHLLVAHDINRYRLLENMFIGGLAASGSIIILLGIIGGIAIRRSLLAKVKDIDQA 191 L G F LLV D++ L + GL + + + LG++G I IR + DI Sbjct: 127 ELPGGFQLLVGRDVSTRAQLRRILRDGLLWALAAMAFLGVLGAIVIRGLFKRSLADISGI 186 Query: 192 ASAIVRGDFTHRLPHHGGESELASLVKTANLMLDQIEQLMKGVINASNSIAHDLRTPLAE 251 AI RGD T R+ G E L +T N MLD+I +LM GV SNSIAHDLRTP+ Sbjct: 187 TRAIARGDLTRRVRRSGNGDEFDELAETINDMLDRIAKLMDGVREVSNSIAHDLRTPITR 246 Query: 252 LRSRLEDLARQEMNSEEVEGAIE----DVDRVISIFNALLRLVEIDTGARRAGFSDMNAA 307 R+RLED A +EE++ A+E D+D ++++F ALLR+ EI+ GARR+ F D++ A Sbjct: 247 ARARLEDAAAHARTTEELQSAVERATLDLDGIVNVFQALLRIAEIEAGARRSAFRDVDLA 306 Query: 308 AVVADVCEFYRPLAESTGKIIDHRPSGPLVLKGDALLLAQAVANLIDNALKFIPIGGKVT 367 V+ D+ EF+ LAE G +I + + GD +L QAV+NL+DNA+KF +V Sbjct: 307 PVLDDLAEFFDALAEERGILIVRDWPKSIPIFGDRDMLQQAVSNLLDNAIKFSRETDRVV 366 Query: 368 LSCVQLDDGRVLVRVSDNGPGISDAELPKVQQRFYRGDTSRSTPGVGLGLSLVASVARLH 427 ++ G V ++++D+GPGI +A+L + +RFYR + +RSTPG GLGL+LV+++A+LH Sbjct: 367 IA-AHAGGGHVEIQIADHGPGIPEADLSRATERFYRAEAARSTPGSGLGLALVSAIAQLH 425 Query: 428 GGSLELSHNHPGLRAVLIL 446 GGSL L +N PGLRA LIL Sbjct: 426 GGSLLLENNEPGLRARLIL 444