BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3136.p (546 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003775860.1| PAS/PAC sensor hybrid histidine kinase [Herb... 941 0.0 ref|YP_001756226.1| histidine kinase [Methylobacterium radiotole... 631 e-178 ref|YP_001858578.1| histidine kinase [Burkholderia phymatum STM8... 624 e-176 ref|YP_001639119.1| histidine kinase [Methylobacterium extorquen... 607 e-171 ref|YP_001924280.1| histidine kinase [Methylobacterium populi BJ... 607 e-171 >ref|YP_003775860.1| PAS/PAC sensor hybrid histidine kinase [Herbaspirillum seropedicae SmR1] gb|ADJ63952.1| PAS/PAC sensor hybrid histidine kinase protein [Herbaspirillum seropedicae SmR1] Length = 552 Score = 941 bits (2433), Expect = 0.0, Method: Composition-based stats. Identities = 468/533 (87%), Positives = 502/533 (94%) Query: 14 ADDFNDAGMRNDHAKVAVGDDANDIFFAAVEMTRMPMIVSDPNKPDNPIIFVNNAFMNMT 73 +D + DAG+RND AKVAVG+D NDIFFAAVEMTRMPMIVSDPN+PDNPI+FVNNAF+NMT Sbjct: 20 SDRYTDAGVRNDLAKVAVGNDINDIFFAAVEMTRMPMIVSDPNRPDNPIVFVNNAFINMT 79 Query: 74 GYSRAEVVGKNCRFLQGPETDRAVVAQVRQAVAEKRELATELLNYRKNGSTFWNALFISP 133 GYS AEVVGKNCRFLQGPETDR+VVA+VR+AVAE+RE+ATELLNYRKNGSTFWNALFISP Sbjct: 80 GYSSAEVVGKNCRFLQGPETDRSVVAEVRRAVAERREIATELLNYRKNGSTFWNALFISP 139 Query: 134 VYDQHGELKYFFSSQLDISRRRDAEQALGQARKMEALGQLTGGIAHDFNNLLQVISGYLD 193 VYDQ G LKYFFSSQLDISRRRDAEQALGQARKMEALGQLTGGIAHDFNNLLQVI+GYLD Sbjct: 140 VYDQQGNLKYFFSSQLDISRRRDAEQALGQARKMEALGQLTGGIAHDFNNLLQVITGYLD 199 Query: 194 IINLALRSDTPDLGRVSRSADSIRKASGKAAMLTQQLLAFARKQRLEGRTINLNSLTEGF 253 +INLALRSD PDL RV+RSADSIRKASGKAAMLTQQLLAFARKQRLEGRTINLNSLTEGF Sbjct: 200 MINLALRSDKPDLARVARSADSIRKASGKAAMLTQQLLAFARKQRLEGRTINLNSLTEGF 259 Query: 254 TDLVQRTLGGDIEVQTELASGLWNCRLDPTQMEVALLNVLINARDAMSGKGTVKIHTSNE 313 TDLV RTLGGDI VQTELA GLWNCRLDPTQMEVALLNVLINARDAM+G+G V+I T+NE Sbjct: 260 TDLVSRTLGGDITVQTELARGLWNCRLDPTQMEVALLNVLINARDAMNGRGRVRIRTANE 319 Query: 314 DLSSEDRAIQLGVKPGLYVCIAVTDNGPGIPADILPRVMDPFFTTKDEGKGTGLGLSMVY 373 DL+ DRA+QLG+K GLYV IAVTD+GPGI DILPRVMDPFFTTKDEGKGTGLGLSMVY Sbjct: 320 DLADPDRAVQLGLKEGLYVSIAVTDDGPGIAPDILPRVMDPFFTTKDEGKGTGLGLSMVY 379 Query: 374 GFVKQSGGSVRIVSSAERGTTVSIYFPATQDQVGGAFEYDNRTHTQGGHEHILVVDDRIE 433 GFVKQSGGSVRI S AE GTTV+IYFPATQDQVGG FEYDNR+ +QGG EHILVVDDR+E Sbjct: 380 GFVKQSGGSVRITSGAEGGTTVTIYFPATQDQVGGGFEYDNRSQSQGGQEHILVVDDRLE 439 Query: 434 VAELAQAMLESLGYRVSMVNSPTEALQVLRSEPKVDLLFTDLIMPGSMNGVVLAREARRM 493 VAELAQ MLESLGYRVSMVNSP EALQ++RS VDLLFTDLIMPGSMNGVVLAREA+RM Sbjct: 440 VAELAQTMLESLGYRVSMVNSPAEALQLIRSGRPVDLLFTDLIMPGSMNGVVLAREAKRM 499 Query: 494 IPSIKILLTTGYASESIERHGADGEFPVLDKPYRHDELARKIRIVLDGATGVS 546 +P+IK+LLTTGYASES+ERHGADGEFPVLDKPYRHDELARKIRIVLDGATGVS Sbjct: 500 LPTIKVLLTTGYASESLERHGADGEFPVLDKPYRHDELARKIRIVLDGATGVS 552 >ref|YP_001756226.1| histidine kinase [Methylobacterium radiotolerans JCM 2831] gb|ACB25543.1| PAS/PAC sensor hybrid histidine kinase [Methylobacterium radiotolerans JCM 2831] Length = 539 Score = 631 bits (1628), Expect = e-178, Method: Composition-based stats. Identities = 323/522 (61%), Positives = 396/522 (75%), Gaps = 2/522 (0%) Query: 25 DHAKVAVGDDANDIFFAAVEMTRMPMIVSDPNKPDNPIIFVNNAFMNMTGYSRAEVVGKN 84 D A + D +DIFFAAVE TRMPMIV+DP +PDNPIIF N AF+ MTGY+ E++G+N Sbjct: 18 DSAPSDISDRKSDIFFAAVETTRMPMIVTDPRQPDNPIIFANRAFLAMTGYTPEELIGRN 77 Query: 85 CRFLQGPETDRAVVAQVRQAVAEKRELATELLNYRKNGSTFWNALFISPVYDQHGELKYF 144 CRFLQGP+TDR VAQVR A+AEKRE ATE+LNYRKNGSTFWNALF+SPVY+ GEL Y+ Sbjct: 78 CRFLQGPDTDRDSVAQVRAAIAEKREFATEILNYRKNGSTFWNALFVSPVYNADGELVYY 137 Query: 145 FSSQLDISRRRDAEQALGQARKMEALGQLTGGIAHDFNNLLQVISGYLDIINLALRSDTP 204 F SQLD+SRRRDAE+ALGQA+KMEALGQLTGGIAHDFNNLLQVI GY+DI+ L Sbjct: 138 FGSQLDVSRRRDAEEALGQAQKMEALGQLTGGIAHDFNNLLQVIVGYVDILAAGLEKPDA 197 Query: 205 DLGRVSRSADSIRKASGKAAMLTQQLLAFARKQRLEGRTINLNSLTEGFTDLVQRTLGGD 264 D R+ R+ ++IR+A+ +A LTQQLLAFARKQRL+GR +NLN+L EG ++V R++G Sbjct: 198 DRARLGRATENIRQAAERATTLTQQLLAFARKQRLDGRAVNLNTLIEGMGEMVARSVGEA 257 Query: 265 IEVQTELASGLWNCRLDPTQMEVALLNVLINARDAMSGKGTVKIHTSNEDLSSEDRAIQL 324 ++V+ +LA LWNCR+DPTQ EVA+LNVLINARDAM GTV+I T N +++S R I Sbjct: 258 VKVELDLAPDLWNCRVDPTQAEVAILNVLINARDAMPEGGTVRISTENSEVASRGREIG- 316 Query: 325 GVKPGLYVCIAVTDNGPGIPADILPRVMDPFFTTKDEGKGTGLGLSMVYGFVKQSGGSVR 384 ++ G YV IA+ D G GIP +L RVMDPFFTTK+EGKGTGLGLSMVYGF KQSGG+ + Sbjct: 317 PLRDGRYVSIAIKDTGTGIPPAVLARVMDPFFTTKEEGKGTGLGLSMVYGFAKQSGGAAQ 376 Query: 385 IVSSAERGTTVSIYFPATQDQVGGAFEYDNRTHTQGGHEHILVVDDRIEVAELAQAMLES 444 I S+ GTTV + FPAT V + R + G E IL+VDDR +VAELA+ +L Sbjct: 377 IESAVGAGTTVRLSFPATDGDVNAPAKISLRAVDRQGTETILIVDDREDVAELARTILRD 436 Query: 445 LGYRVSMVNSPTEALQVLRSEPKVDLLFTDLIMPGSMNGVVLAREARRMIPSIKILLTTG 504 GY + ++ EAL++L S KVDLLFTDLIMPG MNGV+LAREARR P +K+LL TG Sbjct: 437 FGYTTLVASNAREALEILDSSGKVDLLFTDLIMPGGMNGVLLAREARRRQPKLKVLLATG 496 Query: 505 YASESIERHGADG-EFPVLDKPYRHDELARKIRIVLDGATGV 545 YA S+ER G EF +L+KPYR EL R++R +LDG TGV Sbjct: 497 YAEASLERTDIGGSEFDLLNKPYRRTELVRRVRAILDGPTGV 538 >ref|YP_001858578.1| histidine kinase [Burkholderia phymatum STM815] gb|ACC71532.1| PAS/PAC sensor hybrid histidine kinase [Burkholderia phymatum STM815] Length = 533 Score = 624 bits (1609), Expect = e-176, Method: Composition-based stats. Identities = 316/521 (60%), Positives = 400/521 (76%), Gaps = 11/521 (2%) Query: 31 VGDDANDIFFAAVEMTRMPMIVSDPNKPDNPIIFVNNAFMNMTGYSRAEVVGKNCRFLQG 90 + D +DIFFAAV TRMPM+V+DP+ PD+P+IF N+AF+ MTGY E++G NCRFLQG Sbjct: 17 ITDHQDDIFFAAVSTTRMPMVVTDPHLPDHPVIFANHAFLRMTGYELTEIIGSNCRFLQG 76 Query: 91 PETDRAVVAQVRQAVAEKRELATELLNYRKNGSTFWNALFISPVYDQHGELKYFFSSQLD 150 PETDRA + +VR AVA++RELATE+LNYRK+GSTFWNALFISPV+++ GEL YFF SQLD Sbjct: 77 PETDRATIDEVRAAVADRRELATEILNYRKDGSTFWNALFISPVFNEQGELVYFFGSQLD 136 Query: 151 ISRRRDAEQALGQARKMEALGQLTGGIAHDFNNLLQVISGYLDIINLALRSDTPDLGRVS 210 +SRRRDAE AL QA+KMEALGQLTGGIAHDFNNLLQV++GY+D++ + + ++ Sbjct: 137 VSRRRDAEDALHQAQKMEALGQLTGGIAHDFNNLLQVMAGYVDVLQMGIEGHAQS-AVMA 195 Query: 211 RSADSIRKASGKAAMLTQQLLAFARKQRLEGRTINLNSLTEGFTDLVQRTLGGDIEVQTE 270 +S D IR A KA LTQQLLAFARKQ+L GRT+NLN+L +G +L +RTLGG+I ++TE Sbjct: 196 QSLDRIRGAVAKATTLTQQLLAFARKQKLVGRTVNLNTLADGMVELARRTLGGNISLKTE 255 Query: 271 LASGLWNCRLDPTQMEVALLNVLINARDAMSGK--GTVKIHTSNEDLSSEDRAIQLGVKP 328 GL NCR+D TQ+EVALLNVL+NARDA++ + G V + T +L ++ ++ Sbjct: 256 YEEGLGNCRVDSTQLEVALLNVLLNARDALASRRDGVVTVRTETVELEQQETVGFADLRS 315 Query: 329 GLYVCIAVTDNGPGIPADILPRVMDPFFTTKDEGKGTGLGLSMVYGFVKQSGGSVRIVSS 388 G YV IA++DNG GIP +IL RVMDPFFTTK EGKGTGLGLSMVYGF KQSGG+V + S Sbjct: 316 GCYVTIAISDNGCGIPPEILDRVMDPFFTTKGEGKGTGLGLSMVYGFAKQSGGAVNLYSE 375 Query: 389 AERGTTVSIYFPATQDQVGGAFEYD---NRTHTQGGHEHILVVDDRIEVAELAQAMLESL 445 GTT+ +YFPA VGG + + + G+E IL+VDDR+EVAE+AQAMLE + Sbjct: 376 PGVGTTLRLYFPA----VGGIAQRRPSAPKAIEKAGNEMILIVDDRVEVAEVAQAMLEQI 431 Query: 446 GYRVSMVNSPTEALQVLRSEPKVDLLFTDLIMPGSMNGVVLAREARRMIPSIKILLTTGY 505 GYR +V + EA+ +L+ +DLLFTDLIMPG+MNGV+LAREARR+ P IK+LLTTGY Sbjct: 432 GYRTRVVLNTKEAMDILQEGAHLDLLFTDLIMPGNMNGVMLAREARRLHPKIKVLLTTGY 491 Query: 506 ASESIERHGADG-EFPVLDKPYRHDELARKIRIVLDGATGV 545 A S+ER A+G EF ++ KPYR ELARK+RIVL+G TGV Sbjct: 492 ADASMERTDANGSEFDIIHKPYRRAELARKVRIVLNGPTGV 532 >ref|YP_001639119.1| histidine kinase [Methylobacterium extorquens PA1] ref|YP_002420722.1| histidine kinase [Methylobacterium chloromethanicum CM4] ref|YP_002962682.1| sensor hybrid histidine kinase with PAS/PAC and response receiver regulator receiver domains [methylobacterium extorquens AM1] ref|YP_003067865.1| sensor hybrid histidine kinase with PAS/PAC and response receiver regulator receiver domains [Methylobacterium extorquens DM4] gb|ABY30048.1| PAS sensor protein [Methylobacterium extorquens PA1] gb|ACK82794.1| PAS/PAC sensor hybrid histidine kinase [Methylobacterium chloromethanicum CM4] gb|ACS39405.1| putative sensor hybrid histidine kinase with PAS/PAC and response receiver regulator receiver domains [Methylobacterium extorquens AM1] emb|CAX23919.1| putative sensor hybrid histidine kinase with PAS/PAC and response receiver regulator receiver domains [Methylobacterium extorquens DM4] Length = 541 Score = 607 bits (1566), Expect = e-171, Method: Composition-based stats. Identities = 311/546 (56%), Positives = 398/546 (72%), Gaps = 7/546 (1%) Query: 1 MPNTAKHPTVHWPADDFNDAGMRNDHAKVAVGDDANDIFFAAVEMTRMPMIVSDPNKPDN 60 MP++ + P P +G V D +DIFFAAVE TRMPMIV+DP++PDN Sbjct: 1 MPSSPEKPRAPGPNTPVTGSGAS------GVVDQHHDIFFAAVETTRMPMIVTDPHQPDN 54 Query: 61 PIIFVNNAFMNMTGYSRAEVVGKNCRFLQGPETDRAVVAQVRQAVAEKRELATELLNYRK 120 PIIF N AF+ MTGYS E++G NCRFLQGP+TDR V++VR A+ E RE A E+LNYRK Sbjct: 55 PIIFANRAFVRMTGYSAEELIGSNCRFLQGPDTDRDTVSEVRDAIREHREFAAEILNYRK 114 Query: 121 NGSTFWNALFISPVYDQHGELKYFFSSQLDISRRRDAEQALGQARKMEALGQLTGGIAHD 180 +GS+FWNALF+SPV+++ G+L YFF SQLD+SRRRDAE++L QA+KME+LGQLTGGIAHD Sbjct: 115 DGSSFWNALFVSPVFNRSGDLVYFFGSQLDVSRRRDAEESLHQAQKMESLGQLTGGIAHD 174 Query: 181 FNNLLQVISGYLDIINLALRSDTPDLGRVSRSADSIRKASGKAAMLTQQLLAFARKQRLE 240 FNNLLQV+SG+ +++ L T D+ R+ R+ +++R A+ +AA LT QLLAF+RKQRLE Sbjct: 175 FNNLLQVVSGHNEVMLALLDHPTLDVSRMRRAGEAVRAATDRAAKLTHQLLAFSRKQRLE 234 Query: 241 GRTINLNSLTEGFTDLVQRTLGGDIEVQTELASGLWNCRLDPTQMEVALLNVLINARDAM 300 GR +NLN L E ++ RT+G D+ +++ LA LW R+DPTQ EVALLNVLINARDAM Sbjct: 235 GRLLNLNGLVESMGEMAGRTIGDDVVLKSVLAPDLWTTRIDPTQAEVALLNVLINARDAM 294 Query: 301 SGKGTVKIHTSNEDLSSEDRAIQLGVKPGLYVCIAVTDNGPGIPADILPRVMDPFFTTKD 360 G+V + T N + ED A+ V PG YV I+VTD G G+P++IL RVM+PFFTTK Sbjct: 295 PEGGSVTVRTENLLIEDEDTALYKTVPPGAYVVISVTDTGTGMPSEILARVMEPFFTTKG 354 Query: 361 EGKGTGLGLSMVYGFVKQSGGSVRIVSSAERGTTVSIYFPATQDQVGGAFEYDNRTHTQG 420 EGKGTGLGL+MVYGF KQSGGSV+I S GTTV + FPA+ + + R + Sbjct: 355 EGKGTGLGLAMVYGFAKQSGGSVKIYSEVGHGTTVRLLFPASDQKAEEEQKPTIRAADRH 414 Query: 421 GHEHILVVDDRIEVAELAQAMLESLGYRVSMVNSPTEALQVLRSEPKVDLLFTDLIMPGS 480 G E +LVVDDR +VAE A +LE GY+V++V+ P AL +L E ++DLLFTDLIMPG Sbjct: 415 GTETVLVVDDRPDVAETAGIILEDFGYKVTVVDGPKAALDILDGEGRIDLLFTDLIMPGG 474 Query: 481 MNGVVLAREARRMIPSIKILLTTGYASESIERHGADG-EFPVLDKPYRHDELARKIRIVL 539 MNGV+LAR AR P IK+LLTTGYA S+ER A G EF +++KPY+ ELAR++R V+ Sbjct: 475 MNGVMLARAARERQPKIKVLLTTGYAEASMERTDAGGTEFEIINKPYKRMELARRVRRVI 534 Query: 540 DGATGV 545 DG TGV Sbjct: 535 DGPTGV 540 >ref|YP_001924280.1| histidine kinase [Methylobacterium populi BJ001] gb|ACB79745.1| PAS/PAC sensor hybrid histidine kinase [Methylobacterium populi BJ001] Length = 541 Score = 607 bits (1564), Expect = e-171, Method: Composition-based stats. Identities = 310/546 (56%), Positives = 398/546 (72%), Gaps = 7/546 (1%) Query: 1 MPNTAKHPTVHWPADDFNDAGMRNDHAKVAVGDDANDIFFAAVEMTRMPMIVSDPNKPDN 60 MP++ + P+ P + +G V D +DIFFAAVE TRMPMIV+DP +PDN Sbjct: 1 MPSSPEKPSAPGPNTPVSGSG------AAGVIDQHHDIFFAAVERTRMPMIVTDPRQPDN 54 Query: 61 PIIFVNNAFMNMTGYSRAEVVGKNCRFLQGPETDRAVVAQVRQAVAEKRELATELLNYRK 120 PIIF N AF+ MTGY+ E++G NCRFLQGP+TDR V+ VR A+ E RE ATE+LNYRK Sbjct: 55 PIIFANRAFIRMTGYTVDELIGNNCRFLQGPDTDRDTVSDVRDAIREHREFATEILNYRK 114 Query: 121 NGSTFWNALFISPVYDQHGELKYFFSSQLDISRRRDAEQALGQARKMEALGQLTGGIAHD 180 +GS+FWNALF+SPV+++ G+L YFF SQLD+SRRRDAE++L Q++KME+LGQLTGGIAHD Sbjct: 115 DGSSFWNALFVSPVFNRSGDLVYFFGSQLDVSRRRDAEESLHQSQKMESLGQLTGGIAHD 174 Query: 181 FNNLLQVISGYLDIINLALRSDTPDLGRVSRSADSIRKASGKAAMLTQQLLAFARKQRLE 240 FNNLLQV+SG+ +++ L + D+ R+ R+ +++R A+ +AA LT QLLAF+RKQRLE Sbjct: 175 FNNLLQVVSGHNEVLLALLEHPSLDVARMRRAGEAVRAATDRAAKLTHQLLAFSRKQRLE 234 Query: 241 GRTINLNSLTEGFTDLVQRTLGGDIEVQTELASGLWNCRLDPTQMEVALLNVLINARDAM 300 GR +NLN L E ++ RTLG DI +++ LA LW R+DPTQ EVALLNVL+NARDAM Sbjct: 235 GRLLNLNGLVESMGEMAGRTLGDDIVLKSVLAPDLWTTRIDPTQAEVALLNVLLNARDAM 294 Query: 301 SGKGTVKIHTSNEDLSSEDRAIQLGVKPGLYVCIAVTDNGPGIPADILPRVMDPFFTTKD 360 GTV + T N + ED A+ V PG YV I+VTD G G+P++IL RVM+PFFTTK Sbjct: 295 PDGGTVTVRTENLLIEDEDTALYKTVPPGAYVVISVTDTGLGMPSEILSRVMEPFFTTKG 354 Query: 361 EGKGTGLGLSMVYGFVKQSGGSVRIVSSAERGTTVSIYFPATQDQVGGAFEYDNRTHTQG 420 EGKGTGLGL+MVYGF KQSGGSV+I S GTTV + FPA+ +V + R + Sbjct: 355 EGKGTGLGLAMVYGFAKQSGGSVKIYSEVGHGTTVRLLFPASDQKVEDEIKPTTRAADRH 414 Query: 421 GHEHILVVDDRIEVAELAQAMLESLGYRVSMVNSPTEALQVLRSEPKVDLLFTDLIMPGS 480 G E +LVVDDR +VA A +LE GY V +V++P AL +L E ++DLLFTDLIMPG Sbjct: 415 GTETVLVVDDRPDVAATAGTILEDFGYTVLVVDNPVAALDILDGEGRIDLLFTDLIMPGG 474 Query: 481 MNGVVLAREARRMIPSIKILLTTGYASESIERHGADG-EFPVLDKPYRHDELARKIRIVL 539 MNGV+LAR AR P I++LLTTGYA S+ER A G EF +++KPY+ ELAR++R V+ Sbjct: 475 MNGVMLARAARERQPRIRVLLTTGYAEASMERTDAGGTEFEIINKPYKRMELARRVRRVI 534 Query: 540 DGATGV 545 DG TGV Sbjct: 535 DGPTGV 540