BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.3104.p (331 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003774875.1| bifunctional methylenetetrahydrofolate dehyd... 530 e-148 ref|YP_004751563.1| methenyltetrahydrofolate cyclohydrolase [Col... 502 e-140 ref|YP_295513.1| methenyltetrahydrofolate cyclohydrolase [Ralsto... 457 e-126 ref|NP_519717.1| bifunctional: methylenetetrahydrofolate dehydro... 432 e-119 ref|ZP_00942910.1| Methylenetetrahydrofolate dehydrogenase (NADP... 432 e-119 >ref|YP_003774875.1| bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase [Herbaspirillum seropedicae SmR1] gb|ADJ62967.1| bifunctional enzyme: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase protein [Herbaspirillum seropedicae SmR1] Length = 281 Score = 530 bits (1364), Expect = e-148, Method: Composition-based stats. Identities = 275/280 (98%), Positives = 278/280 (99%) Query: 51 MSAQLIDGNLLSQQLRAEVAQRAAALTAQGKQPGLAVILVGDSPASQVYVRNKVKACQDN 110 M AQLIDGNLLSQQLRAEVA+RAAALTAQGKQPGLAVILVGDSPASQVYVRNKVKACQDN Sbjct: 1 MPAQLIDGNLLSQQLRAEVAKRAAALTAQGKQPGLAVILVGDSPASQVYVRNKVKACQDN 60 Query: 111 GLHSVLEKYEASMTEAELLARIDALNADPKINGILVQLPLPAHIDAHKVIEAIAPEKDVD 170 GLHSVLEKYEASMTEAELLARIDALN+DPKINGILVQLPLPAHIDAHKVIEAIAPEKDVD Sbjct: 61 GLHSVLEKYEASMTEAELLARIDALNSDPKINGILVQLPLPAHIDAHKVIEAIAPEKDVD 120 Query: 171 GFHVSNAGLLMTGQPLFRPCTPYGVMKMLESIDYPVRGANAVVVGASNIVGKPQAMLLLQ 230 GFHVSNAGLLMTGQPLFRPCTPYGVMKMLESIDYPVRGANAVVVGASNIVGKPQAMLLLQ Sbjct: 121 GFHVSNAGLLMTGQPLFRPCTPYGVMKMLESIDYPVRGANAVVVGASNIVGKPQAMLLLQ 180 Query: 231 AGATVTICNSKTRDLGHHTRQADILVVATGKRNIVTADMVKPGAVVIDVGMNRDDNGKLC 290 AGATVTICNSKTRDLGHHTRQADILVVATGKRNIVTADMVKPGAVVIDVGMNRDDNGKLC Sbjct: 181 AGATVTICNSKTRDLGHHTRQADILVVATGKRNIVTADMVKPGAVVIDVGMNRDDNGKLC 240 Query: 291 GDVDFANTKEVAGWITPVPGGVGPMTITMLLVNTIEAAER 330 GDVDFAN K+VAGWITPVPGGVGPMTITMLLVNTIEAAER Sbjct: 241 GDVDFANAKDVAGWITPVPGGVGPMTITMLLVNTIEAAER 280 >ref|YP_004751563.1| methenyltetrahydrofolate cyclohydrolase [Collimonas fungivorans Ter331] gb|AEK60740.1| Methenyltetrahydrofolate cyclohydrolase [Collimonas fungivorans Ter331] Length = 290 Score = 502 bits (1293), Expect = e-140, Method: Composition-based stats. Identities = 260/282 (92%), Positives = 272/282 (96%) Query: 49 SAMSAQLIDGNLLSQQLRAEVAQRAAALTAQGKQPGLAVILVGDSPASQVYVRNKVKACQ 108 S M AQLIDGNLLSQQLRA+VA+RAAALTAQGKQPGLAVILVGDSPASQVYVRNKVKAC+ Sbjct: 8 STMPAQLIDGNLLSQQLRADVAKRAAALTAQGKQPGLAVILVGDSPASQVYVRNKVKACE 67 Query: 109 DNGLHSVLEKYEASMTEAELLARIDALNADPKINGILVQLPLPAHIDAHKVIEAIAPEKD 168 DNGLHSVLEKY+A +TEA LLARIDALN DPKINGILVQLPLPAHIDAHKVIEAIA EKD Sbjct: 68 DNGLHSVLEKYDADLTEAALLARIDALNHDPKINGILVQLPLPAHIDAHKVIEAIAAEKD 127 Query: 169 VDGFHVSNAGLLMTGQPLFRPCTPYGVMKMLESIDYPVRGANAVVVGASNIVGKPQAMLL 228 VDGFH+SNAGLLMTGQPLFRPCTPYGVMKMLES+++PVRGA+AV+VGASNIVGKPQAMLL Sbjct: 128 VDGFHISNAGLLMTGQPLFRPCTPYGVMKMLESVNFPVRGAHAVIVGASNIVGKPQAMLL 187 Query: 229 LQAGATVTICNSKTRDLGHHTRQADILVVATGKRNIVTADMVKPGAVVIDVGMNRDDNGK 288 LQAGATVTICNSKTRDLG HTR ADILVVATGKRNIVTADMVKPGA VIDVGMNRDDNGK Sbjct: 188 LQAGATVTICNSKTRDLGLHTRMADILVVATGKRNIVTADMVKPGAAVIDVGMNRDDNGK 247 Query: 289 LCGDVDFANTKEVAGWITPVPGGVGPMTITMLLVNTIEAAER 330 LCGDVDFAN KEVAG+ITPVPGGVGPMTITMLLVNTIEAAER Sbjct: 248 LCGDVDFANAKEVAGYITPVPGGVGPMTITMLLVNTIEAAER 289 >ref|YP_295513.1| methenyltetrahydrofolate cyclohydrolase [Ralstonia eutropha JMP134] sp|Q472L4|FOLD_CUPPJ RecName: Full=Bifunctional protein FolD; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase gb|AAZ60669.1| 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [Ralstonia eutropha JMP134] Length = 283 Score = 457 bits (1176), Expect = e-126, Method: Composition-based stats. Identities = 229/280 (81%), Positives = 255/280 (91%) Query: 51 MSAQLIDGNLLSQQLRAEVAQRAAALTAQGKQPGLAVILVGDSPASQVYVRNKVKACQDN 110 MSAQLIDGN L++Q+R+E A RAA LT +G QPGLAV+LVG+ PASQVYVRNKVKAC+DN Sbjct: 1 MSAQLIDGNALAKQIRSEAAVRAARLTERGHQPGLAVVLVGEDPASQVYVRNKVKACEDN 60 Query: 111 GLHSVLEKYEASMTEAELLARIDALNADPKINGILVQLPLPAHIDAHKVIEAIAPEKDVD 170 G HS L++Y A ++EAELLARIDALN DPKI+GILVQLPLP HID+HKV+EAIAPEKDVD Sbjct: 61 GFHSSLDRYPADLSEAELLARIDALNNDPKIHGILVQLPLPKHIDSHKVLEAIAPEKDVD 120 Query: 171 GFHVSNAGLLMTGQPLFRPCTPYGVMKMLESIDYPVRGANAVVVGASNIVGKPQAMLLLQ 230 GFHV+NAG LMTG PLFRPCTPYG MKMLESI YP+RGA AVVVGASNIVGKP AMLLLQ Sbjct: 121 GFHVANAGALMTGAPLFRPCTPYGCMKMLESISYPLRGARAVVVGASNIVGKPMAMLLLQ 180 Query: 231 AGATVTICNSKTRDLGHHTRQADILVVATGKRNIVTADMVKPGAVVIDVGMNRDDNGKLC 290 AGATVTICNSKTRD+G HTR AD++V A GKRN++TADMVKPGAVVIDVGMNRDDNGKLC Sbjct: 181 AGATVTICNSKTRDIGAHTRDADVIVAAVGKRNLITADMVKPGAVVIDVGMNRDDNGKLC 240 Query: 291 GDVDFANTKEVAGWITPVPGGVGPMTITMLLVNTIEAAER 330 GDVDFA +EVAG+ITPVPGGVGPMTITMLL+NT+EAAER Sbjct: 241 GDVDFAGVREVAGYITPVPGGVGPMTITMLLINTLEAAER 280 >ref|NP_519717.1| bifunctional: methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase [Ralstonia solanacearum GMI1000] sp|Q8XZ10|FOLD_RALSO RecName: Full=Bifunctional protein FolD; Includes: RecName: Full=Methylenetetrahydrofolate dehydrogenase; Includes: RecName: Full=Methenyltetrahydrofolate cyclohydrolase emb|CAD15298.1| probable bifunctional : methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase oxidoreductase protein [Ralstonia solanacearum GMI1000] Length = 289 Score = 432 bits (1112), Expect = e-119, Method: Composition-based stats. Identities = 225/275 (81%), Positives = 249/275 (90%) Query: 51 MSAQLIDGNLLSQQLRAEVAQRAAALTAQGKQPGLAVILVGDSPASQVYVRNKVKACQDN 110 M+AQLIDGN L++QLR E AQRAAALTA+G QPGLAVILVGD PASQVYVRNK+KAC+DN Sbjct: 1 MTAQLIDGNALAKQLRTEAAQRAAALTARGHQPGLAVILVGDDPASQVYVRNKIKACEDN 60 Query: 111 GLHSVLEKYEASMTEAELLARIDALNADPKINGILVQLPLPAHIDAHKVIEAIAPEKDVD 170 G S+ ++Y A +TEA+LL RIDALN DP+I+GILVQLPLP HID+HKV+EAIAPEKDVD Sbjct: 61 GFLSIFDRYPADLTEADLLGRIDALNRDPRIHGILVQLPLPKHIDSHKVLEAIAPEKDVD 120 Query: 171 GFHVSNAGLLMTGQPLFRPCTPYGVMKMLESIDYPVRGANAVVVGASNIVGKPQAMLLLQ 230 GFHV+NAG LMTG PLFRPCTPYG MKMLESIDYPVRGA AVVVGASNIVGKP AMLLLQ Sbjct: 121 GFHVANAGALMTGAPLFRPCTPYGCMKMLESIDYPVRGARAVVVGASNIVGKPMAMLLLQ 180 Query: 231 AGATVTICNSKTRDLGHHTRQADILVVATGKRNIVTADMVKPGAVVIDVGMNRDDNGKLC 290 AGATVTICNSKTRDL HTR+ADI+V A G+RNI+TADMVKPGAVVIDVGMNRDD GKLC Sbjct: 181 AGATVTICNSKTRDLAAHTREADIVVAAVGRRNIITADMVKPGAVVIDVGMNRDDAGKLC 240 Query: 291 GDVDFANTKEVAGWITPVPGGVGPMTITMLLVNTI 325 GDVDFA ++VAG ITPVPGGVGPMTITMLL+NT+ Sbjct: 241 GDVDFAGVRDVAGHITPVPGGVGPMTITMLLINTL 275 >ref|ZP_00942910.1| Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase [Ralstonia solanacearum UW551] ref|YP_002259374.1| bifunctional protein : methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase [Ralstonia solanacearum IPO1609] gb|EAP74664.1| Methylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase [Ralstonia solanacearum UW551] emb|CAQ36302.1| bifunctional protein : methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase [Ralstonia solanacearum MolK2] emb|CAQ61306.1| bifunctional protein : methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase [Ralstonia solanacearum IPO1609] Length = 289 Score = 432 bits (1112), Expect = e-119, Method: Composition-based stats. Identities = 227/275 (82%), Positives = 249/275 (90%) Query: 51 MSAQLIDGNLLSQQLRAEVAQRAAALTAQGKQPGLAVILVGDSPASQVYVRNKVKACQDN 110 M+AQLIDGN L++QLR E AQRAAALTA+G QPGLAVILVG+ PASQVYVRNK+KAC+DN Sbjct: 1 MTAQLIDGNALAKQLRTEAAQRAAALTARGHQPGLAVILVGEDPASQVYVRNKIKACEDN 60 Query: 111 GLHSVLEKYEASMTEAELLARIDALNADPKINGILVQLPLPAHIDAHKVIEAIAPEKDVD 170 G SV ++Y A +TEA+LL RIDALN DP+I+GILVQLPLP HID+HKV+EAIAPEKDVD Sbjct: 61 GFLSVFDRYPADLTEADLLGRIDALNRDPRIHGILVQLPLPKHIDSHKVLEAIAPEKDVD 120 Query: 171 GFHVSNAGLLMTGQPLFRPCTPYGVMKMLESIDYPVRGANAVVVGASNIVGKPQAMLLLQ 230 GFHV+NAG LMTG PLFRPCTPYG MKMLESIDYPVRGA+AVVVGASNIVGKP AMLLLQ Sbjct: 121 GFHVANAGALMTGAPLFRPCTPYGCMKMLESIDYPVRGAHAVVVGASNIVGKPMAMLLLQ 180 Query: 231 AGATVTICNSKTRDLGHHTRQADILVVATGKRNIVTADMVKPGAVVIDVGMNRDDNGKLC 290 AGATVTICNSKTRDL HTR+ADI+V A G+RNI+TADMVKPGA VIDVGMNRDD GKLC Sbjct: 181 AGATVTICNSKTRDLAAHTREADIIVAAVGRRNIITADMVKPGAAVIDVGMNRDDAGKLC 240 Query: 291 GDVDFANTKEVAGWITPVPGGVGPMTITMLLVNTI 325 GDVDFA KEVAG ITPVPGGVGPMTITMLLVNT+ Sbjct: 241 GDVDFAGVKEVAGSITPVPGGVGPMTITMLLVNTL 275