BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.2915.p (379 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_003774924.1| D-isomer specific 2-hydroxyacid dehydrogenas... 575 e-162 ref|ZP_06125194.2| glyoxylate/hydroxypyruvate reductase B [Provi... 387 e-105 ref|YP_002892976.1| D-isomer specific 2-hydroxyacid dehydrogenas... 379 e-103 ref|YP_002892989.1| D-isomer specific 2-hydroxyacid dehydrogenas... 377 e-102 ref|ZP_03699937.1| D-isomer specific 2-hydroxyacid dehydrogenase... 374 e-101 >ref|YP_003774924.1| D-isomer specific 2-hydroxyacid dehydrogenase [Herbaspirillum seropedicae SmR1] gb|ADJ63016.1| D-isomer specific 2-hydroxyacid dehydrogenase protein [Herbaspirillum seropedicae SmR1] Length = 319 Score = 575 bits (1483), Expect = e-162, Method: Composition-based stats. Identities = 289/319 (90%), Positives = 304/319 (95%) Query: 61 MKPHVVVYKKLPEHLLQRLQAECDVTLFDRITQDNRADFLAALKTAHGMIGASLPITNDM 120 MKPHVVVYKKLPEHL+QRLQAE D+TLFDRIT DNRADF+AAL TAHGMIGASLPITN M Sbjct: 1 MKPHVVVYKKLPEHLVQRLQAEFDLTLFDRITDDNRADFIAALATAHGMIGASLPITNAM 60 Query: 121 LEGAPQLRIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILSTARRVVE 180 LE APQL+I STISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALIL++ARRVVE Sbjct: 61 LEAAPQLKIVSTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILASARRVVE 120 Query: 181 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 240 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD Sbjct: 121 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 180 Query: 241 PQAERELDARYVSQDELLAQADFVCVMLPLNADTERLIGAREFALMKRSAIFINASRGRI 300 P+AEREL ARYVS+++LLAQADFVCVMLPL TER+ GA EFALMKRSAIFINASRGRI Sbjct: 181 PEAERELGARYVSKEDLLAQADFVCVMLPLTPQTERMFGAPEFALMKRSAIFINASRGRI 240 Query: 301 VDEAALIAALQDKTIYGAGLDVFEVEPLPAESPLLQLPNVVALPHIGSATHETRLAMAEL 360 VDEAALIAALQDKTI+GAGLDVFEVEPLP +SPLL+LPNVVALPHIGSATHETRLAMAEL Sbjct: 241 VDEAALIAALQDKTIHGAGLDVFEVEPLPLQSPLLKLPNVVALPHIGSATHETRLAMAEL 300 Query: 361 AVCNLLAGLRGEPVPHLAV 379 AV NL+AGLRGEPV HLAV Sbjct: 301 AVTNLIAGLRGEPVAHLAV 319 >ref|ZP_06125194.2| glyoxylate/hydroxypyruvate reductase B [Providencia rettgeri DSM 1131] gb|EFE54227.1| glyoxylate/hydroxypyruvate reductase B [Providencia rettgeri DSM 1131] Length = 330 Score = 387 bits (995), Expect = e-105, Method: Composition-based stats. Identities = 192/312 (61%), Positives = 234/312 (75%) Query: 61 MKPHVVVYKKLPEHLLQRLQAECDVTLFDRITQDNRADFLAALKTAHGMIGASLPITNDM 120 MK ++++YK +P L+RLQ +VT+FD +T +N A F AL A G+IGAS PIT D Sbjct: 7 MKQNIILYKSIPTDQLERLQQHFNVTVFDSVTPENLASFKQALSRADGIIGASYPITADD 66 Query: 121 LEGAPQLRIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILSTARRVVE 180 + AP L+ ASTISVG+D FD+D R + L HTP VLTE TADTIF L+L +ARR++E Sbjct: 67 IANAPNLKAASTISVGIDQFDIDAMNARKIALMHTPNVLTETTADTIFTLVLCSARRIIE 126 Query: 181 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 240 +AE VK G+W SIGE +G NV+GKT+G++GMGRIG AVA+RA+ GFGMP+LY+N Sbjct: 127 MAEMVKNGQWTQSIGEDAYGSNVNGKTIGILGMGRIGYAVAKRAYLGFGMPVLYYNNHIH 186 Query: 241 PQAERELDARYVSQDELLAQADFVCVMLPLNADTERLIGAREFALMKRSAIFINASRGRI 300 P AE +L AR D LLA++DFVCV+LPL+A TE+LIG E A MK SA IN SRGRI Sbjct: 187 PDAETQLKARRCDLDTLLAESDFVCVVLPLSASTEKLIGKNELAKMKPSAFLINGSRGRI 246 Query: 301 VDEAALIAALQDKTIYGAGLDVFEVEPLPAESPLLQLPNVVALPHIGSATHETRLAMAEL 360 VDEAALI AL+ TI GAGLDVFEVEPLP+ S LL LPNVVALPHIGSATHETR AM E Sbjct: 247 VDEAALIDALESGTIRGAGLDVFEVEPLPSNSKLLTLPNVVALPHIGSATHETRYAMVEC 306 Query: 361 AVCNLLAGLRGE 372 AV NL+A L+G+ Sbjct: 307 AVDNLIAALKGD 318 >ref|YP_002892976.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Tolumonas auensis DSM 9187] gb|ACQ93390.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Tolumonas auensis DSM 9187] Length = 324 Score = 379 bits (972), Expect = e-103, Method: Composition-based stats. Identities = 186/316 (58%), Positives = 231/316 (73%) Query: 61 MKPHVVVYKKLPEHLLQRLQAECDVTLFDRITQDNRADFLAALKTAHGMIGASLPITNDM 120 MKP+VV+Y+K+P+ LL +LQ +C VT FD I DNRA F+ AL A G+IG L ++++ Sbjct: 1 MKPNVVLYRKIPDDLLAKLQEQCQVTYFDGINADNRAAFIKALAEAEGVIGVGLQFSDEL 60 Query: 121 LEGAPQLRIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILSTARRVVE 180 + AP+L+ STISVG D+F++ RG+ L HTPGVLTE TADTIF L+L ARR+ E Sbjct: 61 MAAAPKLKAVSTISVGYDDFNVAKLSARGIALMHTPGVLTETTADTIFTLVLCAARRITE 120 Query: 181 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 240 LAE VK G W+GSIG +G NVHGKT+G++GMGRIG AVA+RAH GFGM ++Y+NR Sbjct: 121 LAEKVKQGEWQGSIGPDWYGSNVHGKTIGILGMGRIGYAVAKRAHFGFGMNVIYYNRSAK 180 Query: 241 PQAERELDARYVSQDELLAQADFVCVMLPLNADTERLIGAREFALMKRSAIFINASRGRI 300 P+AE++L+AR S DELLA ADFVC +LPL +T +I A MK SA FIN RG Sbjct: 181 PEAEQQLNARRCSLDELLADADFVCNVLPLMPETRHIINRDTLAKMKPSAFFINGGRGAS 240 Query: 301 VDEAALIAALQDKTIYGAGLDVFEVEPLPAESPLLQLPNVVALPHIGSATHETRLAMAEL 360 VDEAAL+ AL+ I GAGLDVFE EPLP S LL LPNVVALPHIGSATHETR M+++ Sbjct: 241 VDEAALVEALKSGVIKGAGLDVFETEPLPVNSELLSLPNVVALPHIGSATHETRYEMSKM 300 Query: 361 AVCNLLAGLRGEPVPH 376 AV NLLA L+G+ H Sbjct: 301 AVENLLAALKGDLTKH 316 >ref|YP_002892989.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Tolumonas auensis DSM 9187] gb|ACQ93403.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Tolumonas auensis DSM 9187] Length = 325 Score = 377 bits (968), Expect = e-102, Method: Composition-based stats. Identities = 187/312 (59%), Positives = 228/312 (73%) Query: 61 MKPHVVVYKKLPEHLLQRLQAECDVTLFDRITQDNRADFLAALKTAHGMIGASLPITNDM 120 MKP+VV+YK +P L+RLQ+ +V F+ IT NRADF+ AL A G+IGAS PIT D Sbjct: 1 MKPNVVLYKNIPADQLERLQSHFNVAFFEGITDANRADFIGALSNAEGLIGASCPITTDY 60 Query: 121 LEGAPQLRIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILSTARRVVE 180 L AP LR STISVGVD F++ R + L HTP VLTE TADTIF L+L++ARRV+E Sbjct: 61 LNAAPALRAISTISVGVDQFNVPDLTNRKINLMHTPSVLTETTADTIFTLVLNSARRVIE 120 Query: 181 LAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRRPD 240 +AE VK GRW SIG +G +V+GKT+G++GMGRIG AVA+RA+ GFGM +LY+N + Sbjct: 121 MAEMVKEGRWTKSIGVDSYGTDVNGKTIGILGMGRIGYAVAKRAYAGFGMSVLYYNDVAN 180 Query: 241 PQAERELDARYVSQDELLAQADFVCVMLPLNADTERLIGAREFALMKRSAIFINASRGRI 300 P AE++ AR DELLA++DFVCV+LPL +TE+ IG + MK SA IN SRG+I Sbjct: 181 PMAEQDFKARRCELDELLAKSDFVCVVLPLLPETEKFIGKEQLLKMKPSAFLINGSRGKI 240 Query: 301 VDEAALIAALQDKTIYGAGLDVFEVEPLPAESPLLQLPNVVALPHIGSATHETRLAMAEL 360 VDE ALI ALQ I GAGLDVFE EPLPA+SPL+ LPNVVALPHIGSATHETR AM Sbjct: 241 VDETALIEALQQGVIRGAGLDVFEKEPLPADSPLVSLPNVVALPHIGSATHETRYAMVRC 300 Query: 361 AVCNLLAGLRGE 372 AV NL+A L + Sbjct: 301 AVDNLIAALNND 312 >ref|ZP_03699937.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Lutiella nitroferrum 2002] gb|EEG07240.1| D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding [Lutiella nitroferrum 2002] Length = 335 Score = 374 bits (960), Expect = e-101, Method: Composition-based stats. Identities = 201/314 (64%), Positives = 242/314 (77%) Query: 59 IAMKPHVVVYKKLPEHLLQRLQAECDVTLFDRITQDNRADFLAALKTAHGMIGASLPITN 118 +AMK VV YKKLP LL RL + +V FD + NRA F A+ AHG+IG+S+ I Sbjct: 2 LAMKKRVVAYKKLPPALLARLAEQFEVIGFDGVNDTNRAAFAEAVAGAHGLIGSSVRIDA 61 Query: 119 DMLEGAPQLRIASTISVGVDNFDLDYFRQRGLMLAHTPGVLTEATADTIFALILSTARRV 178 +L+ A +L + STISVG D FD+DY +RG++LA+TP VLTE TADT+FALIL+TARRV Sbjct: 62 TLLDPARELELISTISVGYDTFDVDYLTRRGILLANTPDVLTETTADTLFALILATARRV 121 Query: 179 VELAEYVKAGRWKGSIGEAQFGVNVHGKTLGLIGMGRIGSAVARRAHHGFGMPILYHNRR 238 VELAE+VKAG W+ SIG A FGV+VH KTLGLIG+GRIG AVARRA+ GFGM ++Y++R Sbjct: 122 VELAEFVKAGHWQRSIGPAHFGVDVHHKTLGLIGLGRIGQAVARRANLGFGMNVVYYSRH 181 Query: 239 PDPQAERELDARYVSQDELLAQADFVCVMLPLNADTERLIGAREFALMKRSAIFINASRG 298 P+AE AR V +EL A ADFVCV+LPL A+T++LI A FA M+ IFIN SRG Sbjct: 182 AVPEAEAAYGARRVGLNELYASADFVCVVLPLTAETDKLIDADAFARMRPETIFINGSRG 241 Query: 299 RIVDEAALIAALQDKTIYGAGLDVFEVEPLPAESPLLQLPNVVALPHIGSATHETRLAMA 358 IVDEAALI AL+ I+GAGLDVFE EPLPA+SPLLQLPNVVALPHIGSATHETR AMA Sbjct: 242 PIVDEAALIQALKSGAIHGAGLDVFEREPLPADSPLLQLPNVVALPHIGSATHETRFAMA 301 Query: 359 ELAVCNLLAGLRGE 372 E+AV NL+AGL G+ Sbjct: 302 EMAVDNLIAGLNGQ 315