BLASTP 2.2.17 [Aug-26-2007] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= 0001.2743.p (452 letters) Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,459,386 sequences; 5,307,515,862 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ref|YP_002795116.1| hypothetical protein LHK_01115 [Laribacter h... 361 1e-97 ref|YP_003830357.1| GGDEF domain-containing protein [Butyrivibri... 256 5e-66 ref|ZP_05898714.1| putative sensory box-containing diguanylate c... 246 5e-63 ref|ZP_08160992.1| diguanylate cyclase (GGDEF) domain protein [R... 243 4e-62 ref|YP_003893130.1| diguanylate cyclase [Sulfurimonas autotrophi... 229 8e-58 >ref|YP_002795116.1| hypothetical protein LHK_01115 [Laribacter hongkongensis HLHK9] gb|ACO74107.1| GGDEF domain protein [Laribacter hongkongensis HLHK9] Length = 585 Score = 361 bits (927), Expect = 1e-97, Method: Composition-based stats. Identities = 194/445 (43%), Positives = 269/445 (60%), Gaps = 3/445 (0%) Query: 6 LLHHLEADDRDILFFGGGAGDYATLENSFIFHGEQFYRSGMIAVVFCGDDLHIASQDYLG 65 LL L D+ FGGGA D S++ + + +AV CG DL + +LG Sbjct: 140 LLQGLREVRSDLPVFGGGAADLHGFSQSWVMCNGRTFSCAAVAVALCGPDLEVGIWTHLG 199 Query: 66 WQPLSRPMRITSAQDTVVHTIEDKPAFDIYRHYLDLEDDEDFFVNALAFPLMIERDGDLL 125 WQP+ R MR+T + V TI+++PAF+ YRHYL +E DE+FF+N+L FP++++R+G L Sbjct: 200 WQPVGRSMRLTDVEGFNVRTIDNRPAFEAYRHYLGIEADENFFLNSLEFPVLLDRNGAQL 259 Query: 126 ARAPARVLANGALGFAADIKEGETFRLGFGDLDQITANVHQLHESVAQSSPQAIFLYSCC 185 AR P V + +L F AD++ GET G+G + I + E VA +P+ +FLYSC Sbjct: 260 ARIPIAVNDDLSLSFIADLQTGETVHFGYGSIPVILEQTGKTLEQVAAFAPEGLFLYSCS 319 Query: 186 VRRLLMQQDTDIETLPLQRIAPTFGFYTYGEYHGNR-KLNARNATLVAVTLREGEEALSQ 244 R LMQ+D +E IAP GFYTYGE+ G + NATLVAV LREGE Q Sbjct: 320 TRHSLMQEDVQLEISAFHAIAPASGFYTYGEFAGQQGDYQLLNATLVAVGLREGERPYGQ 379 Query: 245 NRDPQIATKAEVSARDPFKKKQIVMAARLTRFIRGVTDELESAHAELKKLAVTDTLTQLC 304 +I + + D ++ + RL F + +EL S++ EL+KL+ TD LT L Sbjct: 380 TGHTRI--EGPLKTFDAISRQHSRILQRLVYFNNVLINELVSSNRELEKLSSTDRLTGLA 437 Query: 305 NRMRLDHMLKDCQGQAQRYAIPFSVILLDIDHFKSVNDGHGHLVGDDVLRQVAAILRDNT 364 NR+RLD + AQR+A FS+ILLD+DHFK VND HGH VGD VL ++AA+LR Sbjct: 438 NRLRLDEEVARQISLAQRHAQEFSLILLDLDHFKLVNDQHGHQVGDRVLIEIAALLRQTL 497 Query: 365 RNVDIAGRWGGEEFLVIVRNGRLEEARLLAEKLRQAIAGAHFPVVNSVTASLGVACFDPE 424 RN D AGRWGGEEFL+++ +E AR +A+KLR+ IAG +F V TAS G+A + Sbjct: 498 RNSDTAGRWGGEEFLIVLPQTSVESARKVADKLRRTIAGHNFGSVGPQTASFGIAVWHTG 557 Query: 425 ESVSSLLDRADNALYAAKRGGRNQV 449 ++ +L R D+A+Y +KR GRN+V Sbjct: 558 DTAKTLFVRVDHAMYQSKRDGRNRV 582 >ref|YP_003830357.1| GGDEF domain-containing protein [Butyrivibrio proteoclasticus B316] gb|ADL33775.1| GGDEF domain-containing protein [Butyrivibrio proteoclasticus B316] Length = 589 Score = 256 bits (655), Expect = 5e-66, Method: Composition-based stats. Identities = 156/457 (34%), Positives = 243/457 (53%), Gaps = 13/457 (2%) Query: 1 METATLLHHLEADDRDILFFGGGAGDYATLE-NSFIFHGEQFYRSGMIAVVFCGDDLHIA 59 + + T+L+ E D+ FGGG+ + E + + + + +G++ + + GDDL + Sbjct: 135 INSHTILNEAEKCRNDVKIFGGGSANVEISEIYTSVMNEDSISHAGVLLITYSGDDLVVD 194 Query: 60 SQDYLGWQPLSRPMRITSAQDTVVHTIEDKPAFDIYRHYLDLEDDEDFFVNALAFPLMIE 119 + +GW+PL + M T + ++ ++ PA IY YLD++ ++DFF N L FP+M Sbjct: 195 VRHAIGWKPLGKDMTATRIEGKRLYELDGVPATQIYSKYLDIQANDDFFSNILEFPIMST 254 Query: 120 RDGDLLARAPARV-LANGALGFAADIKEGETFRLGFGDLDQITANVHQLHESVAQSSPQA 178 + + R P +G++ AAD+ +G L +GD D I +V +L E V +PQA Sbjct: 255 QHDQHVLRLPFSCDPESGSILLAADLDKGTKVNLSYGDPDVIKGDVAELVEHVKDFAPQA 314 Query: 179 IFLYSCCVRRLLMQQDTDIETLPLQRIAPTFGFYTYGE-YHGNRKLNARNATLVAVTLRE 237 +FLYSC VRRL + + ET P ++AP GFY+ GE + L + TL+A+++RE Sbjct: 315 VFLYSCGVRRLYWKYLINKETGPFSQVAPVSGFYSSGEIMRMGKYLIEHHVTLIAISMRE 374 Query: 238 GEEALSQ---NRDPQIATKAEVSARDPFKKKQIVMAARLTRFIRGVTDELESAHAELKKL 294 GE A +Q D I E QI M RL FI EL A+ EL++ Sbjct: 375 GEHAKAQPTGEGDKTIEMSEEQKMHG-----QISMVRRLATFINVTAAELRQANDELRQA 429 Query: 295 AVTDTLTQLCNRMRLDHMLKDCQGQAQRYAIPFSVILLDIDHFKSVNDGHGHLVGDDVLR 354 A TD LT L NR +D +++ + I + + DID FK VND +GH GD +L Sbjct: 430 ADTDALTGLSNRRVIDKVVRSTIATFKTMGIDIVLGIADIDDFKVVNDTYGHAEGDKILV 489 Query: 355 QVAAILRDNTRNV--DIAGRWGGEEFLVIVRNGRLEEARLLAEKLRQAIAGAHFPVVNSV 412 ++ +L + + + GRWGGEEFL + +EEAR L +++RQ IA F + Sbjct: 490 AISDMLNEQICRIPSSLIGRWGGEEFLFMCPRVSIEEARDLLDEIRQKIADTEFGAIGHR 549 Query: 413 TASLGVACFDPEESVSSLLDRADNALYAAKRGGRNQV 449 T S+G+ F ++S + RAD ALY AK G+N++ Sbjct: 550 TISVGMTEFKNDDSADDVFCRADQALYEAKGSGKNRI 586 >ref|ZP_05898714.1| putative sensory box-containing diguanylate cyclase [Selenomonas sputigena ATCC 35185] ref|YP_004414675.1| diguanylate cyclase [Selenomonas sputigena ATCC 35185] gb|EEX77314.1| putative sensory box-containing diguanylate cyclase [Selenomonas sputigena ATCC 35185] gb|AEC01216.1| diguanylate cyclase [Selenomonas sputigena ATCC 35185] Length = 589 Score = 246 bits (628), Expect = 5e-63, Method: Composition-based stats. Identities = 148/450 (32%), Positives = 235/450 (52%), Gaps = 15/450 (3%) Query: 6 LLHHLEADDRDILFFGGGAGDYATLENSFIFHGEQFYRSGMIAVVFCGDDLHIASQDYLG 65 LL L D +I+FFGG D I G +A+VF G++LH +Q G Sbjct: 148 LLGVLSDVDEEIVFFGGLLSDQMNERRITIDLAGHRMSRGFLAIVFVGEELHAKTQISFG 207 Query: 66 WQPLSRPMRITS-AQDTVVHTIEDKPAFDIYRHYLDLEDDEDFFVNALAFPLMIERDGDL 124 W+P ++IT A + + +++KPA + + HYL + + + FP+ ++R+G Sbjct: 208 WKPFGPEVQITRMADERTIVELDEKPASEFFSHYLGIRHCWESLASVETFPMCLKRNGAT 267 Query: 125 LARAPARVLANGALGFAADIKEGETFRLGFGDLDQITANVHQLHESVAQSSPQAIFLYSC 184 LAR + A+G + +AD++EGE R+ GD I + + H + + SP+A+F+ +C Sbjct: 268 LARRLMDIHADGCVYVSADLREGERLRIASGDPIAIISEAQRTHAELCEFSPEAVFIVNC 327 Query: 185 CVRRLLMQQDTDIETLPLQRIAPTFGFYTYGEYHGNR-KLNARNATLVAVTLREGEEALS 243 +++QQ+ E + R PT GFY+Y E+ ++ K N +V++ REGE + Sbjct: 328 MGHYIMLQQNNVYEYAAISRAVPTHGFYSYAEFFRSKGKFMKTNLMMVSIGFREGEPKEA 387 Query: 244 QNRDPQIATKAEVSARDPFKKKQIVMAARLTRFIRGVTDELESAHAELKKLAVTDTLTQL 303 P P +Q + A L F+ +T E ESAH++L LA D LT L Sbjct: 388 PIYKPV----------SPQFGEQTSIIAHLVHFVDAMTKEWESAHSKLVVLAERDALTGL 437 Query: 304 CNRMRLDHMLKDCQGQAQRYAIPFSVILLDIDHFKSVNDGHGHLVGDDVLRQVAAILRDN 363 NR ++ KD A IPF+V++LD+D FK +ND GH +GD+ L +A ILR + Sbjct: 438 MNRRAMERSFKDILHDALASDIPFAVMMLDMDDFKGINDTFGHAMGDEALVALADILRSS 497 Query: 364 TRNVDIAGRWGGEEFLVIVRNGRLEEARLLAEKLRQAIAGAHF--PVVNSVTASLGVACF 421 R+VDI RWGG+EF VI+ + A + E++ + + P SV S+GV Sbjct: 498 VRSVDIVSRWGGDEFFVILTHADRAAAERVVERIHRGASSLSLLMPDKRSVGLSIGVTLS 557 Query: 422 DPEESVSSLLDRADNALYAAKR-GGRNQVV 450 ++ ++ RAD ALY +KR G+N+V+ Sbjct: 558 SAHDTPETVFQRADAALYESKRTAGKNKVI 587 >ref|ZP_08160992.1| diguanylate cyclase (GGDEF) domain protein [Ruminococcus albus 8] gb|EGC01246.1| diguanylate cyclase (GGDEF) domain protein [Ruminococcus albus 8] Length = 575 Score = 243 bits (621), Expect = 4e-62, Method: Composition-based stats. Identities = 150/445 (33%), Positives = 235/445 (52%), Gaps = 33/445 (7%) Query: 16 DILFFGGGA-GDYATLENSFIF-HGEQFYRSGMIAVVFCGDDLHIASQDYLGWQPLSRPM 73 DI FGGGA ++S +F G F G++ + G++LHI S GW+PL + Sbjct: 152 DIQIFGGGAFAPDINAKSSIVFSKGNGFTDHGVVFRLLGGENLHITSTYVTGWKPLGKVF 211 Query: 74 RITSAQDTVVHTIEDKPAFDIYRHYLDLEDDEDFFVNALAFPLMIERDGDLLARAPARVL 133 +T ++ + ++ I+ PA+++YR YL++++DE FF + L FP + +G + RAP L Sbjct: 212 HVTRSEGSRLYEIDHTPAYEVYRKYLNIKNDEHFFNHTLEFPFLYLHNGINILRAPTESL 271 Query: 134 ANGALGFAADIKEGETFRLGFGDLDQITANVHQLHESVAQSSPQAIFLYSCCVRRLLM-Q 192 +G+L +D++ T +L +GD I +V + + + P+ + ++SC RR Sbjct: 272 PDGSLIMTSDMESDVTAQLAYGDPGTILESVREEGRKIYEFKPETVEIFSCAARRSFWGN 331 Query: 193 QDTDIETLPLQRIAPTFGFYTYGEY-HGNRKLNARNATLVAVTLREGEEALSQNRDPQIA 251 + E+ P Q IAPT+GFYT GE+ N +N N T+V V +REG D Sbjct: 332 SEISKESQPFQNIAPTYGFYTSGEFCRTNGHVNQHNVTMVLVGMREG--------DAPAG 383 Query: 252 TKAEVSARDPFKKKQIVMAARLTRFIRGVTDELESAHAELKKLAVTDTLTQLCNRMRLDH 311 AE+ D ++ + RL +I +LE A AVTD LT+L NR + Sbjct: 384 KTAELYVEDGEFTGKMALINRLANYINAAFRDLEEA-------AVTDGLTRLLNRAEIQR 436 Query: 312 MLKDCQGQAQRYAIPFSVILLDIDHFKSVNDGHGHLVGDDVLRQVAAILRDNTRNVDI-- 369 + G+ R P ++I++DID+FKSVND +GH GD+V+ +A +L + +D+ Sbjct: 437 RI----GERLRSGEPLTLIMIDIDNFKSVNDTYGHNEGDNVIVGLANMLH---KGIDVHN 489 Query: 370 ----AGRWGGEEFLVIVRNGRLEEARLLAEKLRQAIAGAHFPVVNSVTASLGVACFDPEE 425 AGRWGGEEF+V++ L A + A FP+ T S+GV PE+ Sbjct: 490 PSACAGRWGGEEFMVMMPYD-LVYTIPAARDMCSDFAALEFPLAGHRTISIGVTAAKPED 548 Query: 426 SVSSLLDRADNALYAAKRGGRNQVV 450 ++ LL R D+ALY AK G+N+ V Sbjct: 549 TLDELLIRVDSALYDAKHSGKNRFV 573 >ref|YP_003893130.1| diguanylate cyclase [Sulfurimonas autotrophica DSM 16294] gb|ADN10118.1| diguanylate cyclase [Sulfurimonas autotrophica DSM 16294] Length = 559 Score = 229 bits (584), Expect = 8e-58, Method: Composition-based stats. Identities = 134/436 (30%), Positives = 225/436 (51%), Gaps = 21/436 (4%) Query: 16 DILFFGGGAGDYATLENSFIFHGEQFYRSGMIAVVFCGDDLHIASQDYLGWQPLSRPMRI 75 +++ GG AGD + +++F E+ +G + +DL + S W + R M + Sbjct: 142 EMVIAGGRAGD-KEFKQTYVFTEEELTDNGCVIATISSNDLIVNSDYIFQWTAVGREMEV 200 Query: 76 TSAQDTVVHTIEDKPAFDIYRHYLDLEDDEDFFVNALAFPLMIERDGDLLARAPARVLAN 135 T +D V++ ++ P DIYR YL + ++ + + FPL++ ++ L+AR P V + Sbjct: 201 TKTKDNVLYELDGIPIIDIYRKYLGEDVVKNMPASCMPFPLVLNKEVLLVARDPVGVTND 260 Query: 136 GALGFAADIKEGETFRLGFGDLDQITANVHQLHESVAQSSPQAIFLYSCCVRRLLMQQDT 195 L F +EG+ R F +++ + +N+ E +A+++YSC R+ L+Q Sbjct: 261 NGLIFGGKFEEGDKVRFSFANIEDLISNLDVYFEKFQSIPAEAVYVYSCVARKALLQNKL 320 Query: 196 DIETLPLQRIAPTFGFYTYGEYHGNRKL-NARNATLVAVTLREGEEALSQNRDPQIATKA 254 E L +AP GF+T+GE+ +RK+ N T + L E S+ + K Sbjct: 321 MDEINILNSLAPAVGFFTFGEFFHSRKIVELLNVTTTFMMLSE-----SKKVLKKKLKKG 375 Query: 255 EVSARDPFKKKQIVMAARLTRFIRGVTDELESAHAELKKLAVTDTLTQLCNRMRLDHMLK 314 ++ DP +K LT ++ T ELE+ ++ D+LT L NR +L+ Sbjct: 376 ALNHFDPIRKA-------LTNLVKVTTQELEN-------ISTHDSLTSLYNRSEYKRILE 421 Query: 315 DCQGQAQRYAIPFSVILLDIDHFKSVNDGHGHLVGDDVLRQVAAILRDNTRNVDIAGRWG 374 AQRY F +I++DID FK VND +GH VGD+VL+ A+IL++ R D RWG Sbjct: 422 KKIKSAQRYGDKFGLIMMDIDFFKRVNDKYGHNVGDEVLKIFASILKEYVREDDFVARWG 481 Query: 375 GEEFLVIVRNGRLEEARLLAEKLRQAIAGAHFPVVNSVTASLGVACFDPEESVSSLLDRA 434 GEEF++I + +E L +KL++ IA F + AS G+ + ++ S+ R Sbjct: 482 GEEFIIIANHAGNKELEKLTKKLQKEIAKTSFAPAPQLCASFGLTAYIAGDTEESIFKRV 541 Query: 435 DNALYAAKRGGRNQVV 450 D+ALY AK+ GR++ + Sbjct: 542 DDALYMAKQTGRDKYI 557